Tag Archives: Diagnostic Markers

Earlier Diagnosis of Glaucoma – and Possibly Many Neurodegenerative Diseases – By Retinal Examination? (BBC News / NHS Choices / Brain)

Summary A fluorescent dye injected into the bloodstream may, in future, provide a convenient method of detecting glaucoma earlier – perhaps a decade before more overt symptoms and damage have had the opportunity to develop – by identifying changes in … Continue reading

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Skin Cells: A New Non-Invasive Biomarker? (BBC News / American Academy of Neurology)

Summary Skin may be a good candidate biomarker for detecting hidden brain disorders earlier. Abnormal proteins which accumulate in the brain in neurodegenerative disorders such as Alzheimer’s Disease and Parkinson’s Disease can be found in the skin too. Research is … Continue reading

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Dementia Diagnosis and Prediction Using Eye Examinations? (BBC News)

Summary A £1.1m three year study involving researchers from Dundee University and Edinburgh will investigate whether eye tests can aid non-invasive diagnosis by providing an “early warning” of Alzheimer’s Disease and other conditions. It is thought that changes in the eye … Continue reading

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Future Dementia Diagnosis or Prediction Via Eye Examinations? (BBC News / US Society for Neuroscience Conference)

Summary The retina is a direct extension of the brain. Early research has discovered that mice genetically engineered to have a version of Alzheimer’s Disease show a corresponding loss thickness in a layer of specific cells in the retina, and … Continue reading

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Blood Test Could Assist Early Diagnosis of Alzheimer’s Disease (BBC News)

Summary Researchers at the University of Nottingham are developing a quick and easy blood test to detect proteins linked strongly with Alzheimer’s Disease, such as amyloid and APOE, in combination with other markers linked to inflammation. The test has not been fully validated yet, and could be … Continue reading

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Brain Scans Distinguish Between Dementia Types (BBC News / Neurology)

Summary Scientists at the University of Pennsylvania believe they may have discovered how to distinguish between different types of dementia without the need for invasive lumbar puncture tests to obtain cerebrospinal fluid (csf).  Alzheimer’s and frontotemporal dementia share similar features and symptoms and can … Continue reading

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Brain Functional Networks as Diagnostic Markers (Future Directions in the Diagnosis and Assessment of Dementia?)

Abstract This article reviews various non-invasive biomarkers which might be used to detect Alzheimer’s Disease in its earliest pre-dementia stages. The feasibility of neuroimaging tools, such as MR, SPECT, and FDG-PET imaging are examined, as are neurophysiological measurements using EEG. … Continue reading

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