Tag Archives: DLB

Dementia with Lewy Bodies: Updated DLB Consortium Diagnosis and Management Consensus Report (Neurology)

Summary The Dementia with Lewy Bodies (DLB) Consortium has published an updated set of recommendations on diagnosis and management of DLB. Clinical features and diagnostic biomarkers are covered, with guidance on their interpretation. Previously omitted aspects of Lewy-related pathology are … Continue reading

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Exploring Disease-Modifying Treatments for Lewy-Body Dementia (Frontiers in Neuroscience)

Summary The authors of this review remind readers that there are currently no disease-modifying therapies for Dementia with Lewy bodies (DLB). DLB accounts for perhaps 25% of all dementia cases. This review covers therapeutic directions which have been explored for … Continue reading

Posted in Acute Hospitals, Community Care, For Doctors (mostly), For Nurses and Therapists (mostly), For Researchers (mostly), International, Mental Health, Models of Dementia Care, Quick Insights, Systematic Reviews | Tagged , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , | Leave a comment

SPECT Imaging of Suspected Dementia with Lewy Bodies (BMJ Open)

Summary This article reviews progress in the use of Single-Photon Emission Computed Tomography (SPECT) for the diagnosis of Dementia with Lewy Bodies (DLB). The authors conclude that systematic visual analyses of ((123)I)FP-CIT SPECT images may be used to detect people … Continue reading

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REM Sleep Behaviour Disorder: an Early Window on Neurodegeneration (Tremor and Other Hyperkinetic Movements)

Summary Rapid eye movement (REM) sleep behaviour disorder (RBD), involving loss of the normal atonia during REM sleep and causing patients to “act out” their dreams, offers several promising research opportunities. Patients with RBD are at high risk of developing synuclein-mediated … Continue reading

Posted in For Doctors (mostly), For Researchers (mostly), International, Quick Insights, Universal Interest | Tagged , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , | 1 Comment

Review and Timeline of Lewy Pathology (Nature Reviews. Neurology)

Summary This article traces developments in Lewy pathology since Fritz Heinrich Lewy’s 1912 discovery of the protein aggregates underlying Parkinson Disease (PD) in brain regions other than the substantia nigra. It was Konstantin Nikolaevich Tretiakoff who in 1919 found similar … Continue reading

Posted in For Doctors (mostly), For Researchers (mostly), International, Parkinson's Disease, Quick Insights, Systematic Reviews, UK, Universal Interest | Tagged , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , | Leave a comment

Rapid Eye Movement (REM) Sleep Behaviour Disorder May Predict Development of Dementia With Lewy Bodies (Mayo Clinic News)

Summary Rapid eye movement (REM) sleep behaviour disorder is caused by the loss of the normal muscle paralysis during REM sleep. This tendency to “act out dreams” can appear three decades or more before a formal diagnosis of dementia with Lewy bodies in males, … Continue reading

Posted in Diagnosis, For Doctors (mostly), For Researchers (mostly), International, Quick Insights, Universal Interest | Tagged , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , | Leave a comment

Government Announces £22 Million For Dementia Research (Alzheimer’s Society / Department of Health / NIHR)

[A version of this item features in Dementia and Elderly Care: the Latest Evidence Newsletter (RWNHST), Volume 3 Issue 5, January 2013]. Summary Health Secretary Jeremy Hunt has announced that Government spending on dementia research will be boosted by two-thirds, with a £22 … Continue reading

Posted in Alzheimer's Society, Alzheimer’s Research UK, Delirium, Department of Health, Diagnosis, End of Life Care, Falls, Falls Prevention, For Researchers (mostly), Hypertension, In the News, Management of Condition, National, NIHR, Pain, Patient Care Pathway, Person-Centred Care, Telecare, UK, Universal Interest | Tagged , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , | Leave a comment