Tag Archives: Dreaming in Dementia: REM Sleep Behaviour Disorder and Synucleinopathy

Lancet Seminar on Parkinson’s Disease (Lancet / Advances in Integrative Medicine / Translational Proteomics / Parkinson’s UK / BBC News)

Summary Coinciding with Parkinson’s Awareness Week 2015 (April 20th – 26th 2015), the following Lancet review / seminar covers the clinical features, risk factors, pathology, genetics, pathogenesis, diagnosis and treatment of Parkinson’s Disease. Full Text Link (Note: This article requires … Continue reading

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SPECT Imaging of Suspected Dementia with Lewy Bodies (BMJ Open)

Summary This article reviews progress in the use of Single-Photon Emission Computed Tomography (SPECT) for the diagnosis of Dementia with Lewy Bodies (DLB). The authors conclude that systematic visual analyses of ((123)I)FP-CIT SPECT images may be used to detect people … Continue reading

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REM Sleep Behaviour Disorder: an Early Window on Neurodegeneration (Tremor and Other Hyperkinetic Movements)

Summary Rapid eye movement (REM) sleep behaviour disorder (RBD), involving loss of the normal atonia during REM sleep and causing patients to “act out” their dreams, offers several promising research opportunities. Patients with RBD are at high risk of developing synuclein-mediated … Continue reading

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Rapid Eye Movement (REM) Sleep Behaviour Disorder May Predict Development of Dementia With Lewy Bodies (Mayo Clinic News)

Summary Rapid eye movement (REM) sleep behaviour disorder is caused by the loss of the normal muscle paralysis during REM sleep. This tendency to “act out dreams” can appear three decades or more before a formal diagnosis of dementia with Lewy bodies in males, … Continue reading

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