Tag Archives: Drosophila melanogaster

Dementia Research Centre in Wales (BBC News)

Posted on October 26, 2018 by Dementia and Elderly Care News

Summary A brief piece, from BBC News, on the work and aims of the £20 million Dementia Research Institute at Cardiff University. Full Text Link Reference Clarke, O. (2018). Fruit flies’ brains studied to help crack dementia. London: BBC Health … Continue reading →

Posted in BBC News, For Researchers (mostly), In the News, National, Quick Insights, UK, Universal Interest, Wales | Tagged BBC Health News, BBC Wales News, Biomarkers Research Programmes, Bioscience Careers, Brain Research Imaging Centre at Cardiff University (CUBRIC), Cardiff University, Dementia Action Plan for Wales: 2018-2022, Dementia Research, Dementia Research Careers, Dementia Research Institute (Cardiff), Dementia Research Institute (DRI), Dementia Research Institute at Cardiff University, Drosophila melanogaster, Fruit Flies, Genetic Research, Immune Pathways and Stem Cell (iPSC) Models of Neurodegenerative Disease, Immunology, Inflammation, Inflammatory Response, National Dementia Vision for Wales, Neurodegenerative Disease Research, Neurodegenerative Diseases, Neurodegenerative Disorders, Neurodegenerative Research, Neurodevelopmental Disorders: Abnormal Brain Development, Neuroinflammation, Neuroinflammation Research Cluster, Neuroscience, Research and Development, Research and Innovation, Research Careers, Research Commitment, Research Culture, Research Funding, Transgenic Drosophila, Vaughan Gething: Welsh Health Secretary, Welsh Government, Welsh Government Dementia Oversight of Implementation and Impact Group (DOIIG) | Leave a comment

Lithium and Ageing? (BBC News / Cell Reports)

Posted on April 13, 2016 by Dementia and Elderly Care News

Summary Low doses of the drug lithium appear to have a potential impact on prolonging longevity, in short-lived fruit flies at least (and under laboratory conditions). Full Text Link Reference Lithium study helps scientists unlock ageing puzzle. London: BBC Health … Continue reading →

Posted in Animal Studies, BBC News, For Researchers (mostly), In the News, International, Quick Insights | Tagged Ageing Research, BBC Health News, Biological Ageing, Blocking of GSK-3 Chemical, Cell Ageing, Cell Reports, Cellular Level Ageing, Department of Genetics Evolution and Environment: University College London, Department of Molecular Neuroscience: University College London, Drosophila melanogaster, European Bioinformatics Institute (EMBL-EBI), European Molecular Biology Laboratory, Fruit Flies, Germany, GSK3/NRF2-Dependent Hormesis, Institute of Healthy Ageing: University College London, Institute of Neurology: University College London, Lithium, Lithium and Ageing, Lithium and Longevity, Max Planck Institute for Biology of Ageing, UCL Cancer Institute, UCL Institute of Healthy Ageing, University College London, Wellcome Trust Genome Campus (Cambridge) | Leave a comment

Frontotemporal Dementia: Basic Disease Processes Uncovered? (Alzheimer’s Society / Journal of Cell Biology)

Posted on April 1, 2015 by Dementia and Elderly Care News

Summary Researchers studying the connections between neurons in fruit flies may have identified mechanisms which are involved neurodegeneration in Frontotemporal Dementia (FTD). FTD affects the frontal and temporal lobes (in human brains). A protein called CHMP2B can cause neuronal connections … Continue reading →

Posted in Alzheimer's Society, Animal Studies, Charitable Bodies, For Doctors (mostly), For Researchers (mostly), International, Quick Insights, UK, Universal Interest | Tagged Activator Protein-1), Age-Related Neurodegenerative and Neurovascular Diseases, c-Jun N-terminal kinase (JNK), CHMP2B, Disease Modifying Treatment by 2025 (Aim), Drosophila melanogaster, Endosomal JNK-Scaffold POSH (Plenty-of-SH3s), ESCRT-III Dysfunction, Frontotemporal Dementia, Frontotemporal Dementia (FTD), Fruit Flies, Fruit Fly Model of Frontotemporal Dementia, JCB: Journal of Cell Biology, Journal of Cell Biology, Neurodegeneration, Neurodegenerative Disease Research, Neurodegenerative Diseases, Neurodegenerative Disorders, Neurodegenerative Research, Neurology, Novel Targets in Neurodegeneration, Pick’s Disease (Frontotemporal Dementia), POSH (Plenty-of-SH3s), Potential Drug Targets, RAB8 Deficiency, Rab8 POSH and TAK1 (Regulation of Synaptic Growth), RAB8 Protein, Synaptic Overgrowth and Endosomal Dysfunction, Transgenic Drosophila | Leave a comment

Ibuprofen for Longevity? (NHS Choices / PLOS Genetics)

Posted on January 4, 2015 by Dementia and Elderly Care News

Summary The following NHS Choices Behind the Headlines critical appraisal covers recent research involving yeast, microscopic worms and fruit flies, which has been misinterpreted in the press as implying that taking ibuprofen regularly might extend human lifespan (by inhibiting tryptophan … Continue reading →

Posted in Animal Studies, For Doctors (mostly), For Nurses and Therapists (mostly), For Researchers (mostly), In the News, International, NHS Digital (Previously NHS Choices), Quick Insights | Tagged Ageing, Aromatic Amino Acid Import, Bazian, Behind the Headlines, Buck Institute for Research on Aging, Caenorhabditis elegans, Cell Ageing, Cellular Level Ageing, Department of Biochemistry and Biophysics: Texas A&M University, Department of Pathology: University of Washington, Drosophila melanogaster, Enhanced Longevity by Ibuprofen, Fruit Flies, Ibuprofen, Ibuprofen and Longevity, Ibuprofen and the Reduced Risk of Alzheimer’s Disease Link, Ibuprofen and the Reduced Risk of Parkinson’s Disease Link, Ibuprofen Use and Reduced Risk of Parkinson Disease, Inhibition of Tryptophan Import, Institute of Biology of Komi Science Center of Ural Branch of RAS (Russia); Syktyvkar State University (Russia), Long-Term Ibuprofen Use, Longevity, Microscopic Worms, National Science Foundation, National Science Foundation (NSF), PLOS Genetics, Replicative Lifespan (RLS), Saccharomyces cerevisiae, Tat2p, Texas A&M University, Tryptophan, United States, University of Washington, US National Institutes of Health, US National Science Foundation, USA, Yeast | Leave a comment

Fungal Mould Implicated in Parkinson’s Disease? (NHS Choices / Proceedings of the National Academy of Sciences of the United States of America)

Posted on November 18, 2013 by Dementia and Elderly Care News

Summary A recent NHS Choices critical appraisal has covered research which has been misunderstood by the media as implying that living in mouldy environments can increase the risk of developing Parkinson’s Disease. Researchers exposed fruit flies to 1-octen-3-ol; a molecule … Continue reading →

Posted in Animal Studies, For Doctors (mostly), For Researchers (mostly), In the News, International, NHS Digital (Previously NHS Choices), Parkinson's Disease, Quick Insights | Tagged Behind the Headlines, Critical Appraisals, Department of Plant Biology and Pathology: Rutgers, Dopamine, Dopamine Neuron Degeneration, Drosophila melanogaster, Fruit Flies, Fungal Mould, Fungal-Derived Semiochemical 1-octen-3-ol, Human Plasma Membrane Dopamine Transporter (DAT), Mould, Mouldy Environments, National Institutes of Health (NIH), Neurodegeneration, New Brunswick and Emory University, Parkinsonism, Proceedings of the National Academy of Sciences (PNAS), Proceedings of the National Academy of Sciences of the United States of America (PNAS), Risk Factors, Rutgers University Research Fund, Rutgers: State University of New Jersey, Tyrosine Hydroxylase, United States, USA, Vesicular Monoamine Transporter (VMAT), VMAT2, Volatile Fungal Semiochemical 1-octen-3-ol | Leave a comment

Alzheimer’s Research UK’s Virtual Lab Tour (Alzheimer’s Research UK / Department of Health: Dementia Challenge)

Posted on July 18, 2013 by Dementia and Elderly Care News

Summary Alzheimer’s Research UK has launched a virtual laboratory tour, entitled “The Lab”, which explains the purpose, funding and ongoing achievements of dementia research. Read more: Alzheimer’s Research UK launches virtual lab tour. Reference Alzheimer’s Research UK launches virtual lab tour. London: Department of Health, June 23rd … Continue reading →

Posted in Alzheimer’s Research UK, Animal Studies, BBC News, Charitable Bodies, For Carers (mostly), For Researchers (mostly), In the News, National, Non-Pharmacological Treatments, Patient Care Pathway, Patient Information, Quick Insights, UK, Universal Interest | Tagged Alzheimer's Research UK, Alzheimer’s Research UK's Virtual Lab Tour, Animal Research, Animals (Scientific Procedures) Act 1986, BBC Health News, Brain Imaging, Dementia Research, Drosophila melanogaster, Genetic Tests, Genetics of Alzheimer's Disease, Innovation in Genetics, Magnetic Resonance Imaging (MRI), Medical Research, MRI Brain Imaging, Research and Development, Research and Innovation, Research Funding, Three Rs of Animal Research: Replacement Refinement and Reduction, Tilt, Transgenic Drosophila, Translational Research, Virtual Lab: Alzheimer’s Research UK | Leave a comment

Structure of Neurodegenerative Disease Molecule Mapped (NHS Choices / Nature / Mancunian Matters)

Posted on April 15, 2013 by Dementia and Elderly Care News

Summary Researchers from the University of Manchester, the University of Leicester and institutions in Portugal, France and Germany have performed early-stage research into the structure of an enzyme (Kynurenine 3-Monooxygenase, or KMO) which has been implicated in the development of … Continue reading →

Posted in Animal Studies, For Doctors (mostly), For Researchers (mostly), In the News, International, NHS Digital (Previously NHS Choices), Quick Insights, UK, Universal Interest | Tagged Alzheimer's Disease, Behind the Headlines, Cell and Molecular Neuroscience Unit, Center for Nanoscale Microscopy and Molecular Physiology of the Brain: University Medical Center Göttingen, Department of Genetics: University of Leicester, Department of Neurodegeneration and Restorative Research; Center for Nanoscale Microscopy and Molecular Physiology of the Brain: University Medical Center Göttingen, Drosophila melanogaster, Faculdade de Medicina da Universidade de Lisboa: Portugal, France, Germany, Huntington’s Disease, Institut de Chimie Organique et Analytique: Université d’Orléans, Instituto de Fisiologia; Faculdade de Medicina da Universidade de Lisboa: Portugal, Instituto de Medicina Molecular; Lisboa: Portugal, Kynurenine 3-Monooxygenase (KMO), Manchester Institute of Biotechnology: University of Manchester, Mancunian Matters, Nature, Neurodegeneration, Neurodegenerative Disease Research, Neurodegenerative Diseases, Parkinson’s Disease, Portugal, Saccharomyces cerevisiae, Université d’Orléans, University Medical Center Göttingen, University of Leicester, University of Manchester, UPF 648 | Leave a comment

Tag Archives: Drosophila melanogaster

Dementia Research Centre in Wales (BBC News)

Lithium and Ageing? (BBC News / Cell Reports)

Ibuprofen for Longevity? (NHS Choices / PLOS Genetics)

Fungal Mould Implicated in Parkinson’s Disease? (NHS Choices / Proceedings of the National Academy of Sciences of the United States of America)

Alzheimer’s Research UK’s Virtual Lab Tour (Alzheimer’s Research UK / Department of Health: Dementia Challenge)

Structure of Neurodegenerative Disease Molecule Mapped (NHS Choices / Nature / Mancunian Matters)

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