Tag Archives: Early-Onset Dementia

More on the Possible Role of Neuroinflammation in Frontotemporal Dementia (Bazian / Brain)

Posted on March 22, 2020 by Dementia and Elderly Care News

Summary Inflammation in the brain has been found to be present alongside (“co-localised” with) protein clusters in patients with frontotemporal dementia, suggesting that neuroinflammation may be involved as a potential cause of frontotemporal dementia. “The researchers found that both the … Continue reading →

Posted in For Doctors (mostly), For Nurses and Therapists (mostly), For Researchers (mostly), In the News, International, NHS Digital (Previously NHS Choices), Quick Insights, UK, Universal Interest | Tagged Association of British Neurologists, Bazian, Behavioural Frontotemporal Dementia (bvFTD), Behavioural Variant Frontotemporal Dementia (bvFTD), Behind the Headlines, Biomarker Development, Biomarkers, Biomarkers for Inflammation, Brain (Journal), Brain Autopsies, Brain Inflammation, C-PK-11195, C-PK-11195 (Biomarker for Inflammation), Cambridge Brain Bank, Cambridge Centre for Parkinson-Plus, Cambridge University Hospitals NHS Foundation Trust, Consiglio Nazionale delle Ricerche (CNR), Critical Appraisals, Degenerative Tauopathy, Department of Clinical Neurosciences: Cambridge University, Department of Neurology: Walton Centre (Liverpool), Department of Pathology: Cambridge University Hospitals NHS Foundation Trust, Department of Psychiatry: University of Cambridge, Division of Anaesthesia: University of Cambridge, Early-Onset Dementia, F-AV-1451, F-AV-1451 (Biomarker for Protein Clusters), Fronto-Temporal Dementia (FTD), Frontotemporal Dementia, Frontotemporal Dementia (FTD), FTD: Fronto-Temporal Dementia, FTLD-Pick’s, FTLD-TDP (A), FTLD-TDP (C), FTLD-TDP (Types A and C), FTLD-TDP-43, Immune Cells (Microglia), Inflammation, Inflammation and Neurodegenerative Diseases, Istituto di Bioimmagini e Fisiologia Molecolare (IBFM): Consiglio Nazionale delle Ricerche (CNR), Italy, Lundbeck Foundation (Denmark), Medical Research Council (MRC), Medical Research Council Cognition and Brain Sciences Unit: University of Cambridge, Microglia, Monoamine Oxidase (MAO), National Institute of Health Research, Neurodegenerative Disease Research, Neurodegenerative Diseases, Neurodegenerative Disorders, Neuroinflammation, Neuroinflammation and Frontotemporal Dementia, Neuroinflammation and Protein Aggregation, Neuromelanin, NIHR Dementias and Neurodegenerative Diseases Research Network, Non-Amyloid-β Protein Aggregation, Non-Fluent Variant Primary Progressive Aphasia (nfvPPA), Patrick Berthoud Charitable Trust, PET Scans, Pick’s Disease (Frontotemporal Dementia), Positron Emission Tomography (PET), Protein Aggregation, Protein Clusters, Semantic Variant Primary Progressive Aphasia (svPPA), Tauopathy, TDP-43, TDP-43 Pathology, TDP-43 Protein, TDP-43 Proteinopathy, University of Cambridge, Variants of Primary Progressive Aphasia (PPA), Wellcome Trust, Wolfson Brain Imaging Centre: University of Cambridge | Leave a comment

ESRC-NIHR Dementia Research Initiative: Funding or Four Dementia Research Projects (NIHR)

Posted on January 23, 2019 by Dementia and Elderly Care News

Summary The National Institute for Health Research (NIHR) and the Economic and Social Research Council (ESRC) have announced further funding for research projects aiming to improve the lives of people living with dementia and their carers. The four projects comprise … Continue reading →

Posted in Universal Interest | Tagged and consequences of INequalities in people with Dementia and their family carers, APPLE Tree Programme: Active Prevention in People at risk of dementia through Lifestyle, Australia, Bangor University, bEhaviour change and Technology to build REsiliEnce, Brighton and Sussex Medical School, Brighton and Sussex Medical School: University of Sussex, Canterbury Christ Church University, care and costs, Caregiver Burden, Caregivers, Caregiving (Carers), Carer Awareness, Carer Burden in Dementia, Carer Experience, Carer Fatigue, Carer Friendly Communities, Carer Friendly Policies, Carer Friendly Society, Carer Isolation, Carer Support, Carer Support Services, Carer's Needs, Carers, Carers and Families, Caring for Carers, Caroline Dinenage MP: Minister of State for Care, Dementia Research, Dementia Research Centre: University College London, Dementia Research Initiative, Dementia Support Groups, DETERMIND: DETERMinants of quality of life, Early-Onset Dementia, Economic and Social Research Council (ESRC), EMpowering Better End of life Dementia Care (EMBED-Care Programme), ESRC-NIHR Dementia Research Initiative 2018, Family Carers, France, Frontotemporal Dementia, Inequalities in Service Use and Outcomes for People With Dementia, INSERM (Institut National de la Santé et de la Recherche Médicale), Kings College London, Lifestyle Behaviour Change and Technology for Prevention of Dementia in People at Risk, London School of Economics (LSE), Multicomponent Support Groups for Persons Living With Rare Dementias, National Institute for Health Research (NIHR), Newcastle University, North East London NHS Foundation Trust, Online Support Groups, Palliative Care for Dementia, Posterior Cortical Atrophy, Rare Dementia Support (London), Rare Dementias, UK Dementia Research Topics and Subtopics: Frontotemporal Dementia, UK Dementia Research Topics and Subtopics: Posterior Cortical Atrophy, United States, University College of London (UCL), University of Cambridge, University of East Anglia, University of Exeter, University of Michigan, University of New South Wales, University of Sussex, University of York, Unmet Needs of Family Carers, USA, Young Onset Dementia (YOD) | Leave a comment

Investigations Into the Early Signs, Symptoms and Family Experiences of Alzheimer’s Disease (BMJ Open / International Psychogeriatrics)

Posted on May 23, 2018 by Dementia and Elderly Care News

Summary A literature review analyses the sequence / timing of the early signs and symptoms of Alzheimer’s Disease. The authors distinguish between the early signs of late-onset Alzheimer’s Disease (LOAD) and those of early-onset Alzheimer’s Disease (EOAD). Full Text Link … Continue reading →

Posted in Community Care, Depression, Diagnosis, For Carers (mostly), For Doctors (mostly), For Nurses and Therapists (mostly), For Researchers (mostly), For Social Workers (mostly), International, Mental Health, Models of Dementia Care, Quick Insights, Systematic Reviews, UK, Universal Interest | Tagged Aberrant Motor Behaviour, Acalculia, Agitation, Alexia, Anomia, Anosognosia, Anxiety, Apathy, Australia, BMJ Open, BMJ Publishing Group Ltd, Box Hill Hospital (Victoria), Cognitive Impairment, Conversion to Dementia From Prodromal Disease, Disinhibition, Early Detection of Preclinical Disease, Early Signs and Symptoms of Alzheimer's Disease, Early-Onset Alzheimer’s Disease (EOAD), Early-Onset Dementia, Eastern Cognitive Disorders Clinic: Box Hill Hospital, Experiences, Experiences of the Transition to Dementia, Family and Caregiver Experiences, Family Members' Experiences of Pre-Diagnostic Phase of Dementia, Hallucination, Initial Onset and Diagnosis, Institute for Health Research: University of Bedfordshire, International Psychogeriatrics, Irritability, Late Onset Dementia, Late-Onset Alzheimer's Disease, Late-Onset Alzheimer's Disease (LOAD), Melbourne School of Psychological Sciences: University of Melbourne, Neuroscience Department: Box Hill Hospital, Olfactory Disturbances, Patient and Carer Experiences, Patient Experiences, Pre-Diagnostic Phase of Dementia, Preclinical Alzheimer's Disease, Preclinical Indicators in Alzheimer's Disease, Preclinical Phase of Dementia, Prodromal Alzheimer's Disease, School of Life Sciences: University of Hull, Signs and Symptoms of Alzheimer's Disease, University of Bedfordshire, University of Hull, University of Melbourne, Weight Loss, Young Onset Dementia (YOD), Young-Onset Dementia | Leave a comment

Heavy Drinking: an Under-Appreciated Dementia Risk Factor? (BBC News / Lancet Public Health)

Posted on February 21, 2018 by Dementia and Elderly Care News

Summary Research based in France has discovered an association between alcohol use disorders and dementia risk, particularly regarding the risk of developing early-onset dementia (i.e. with onset at an age less than 65 years). Full Text Link Reference Alcohol and … Continue reading →

Posted in BBC News, Community Care, For Carers (mostly), For Doctors (mostly), For Nurses and Therapists (mostly), For Researchers (mostly), For Social Workers (mostly), In the News, International, Mental Health, Quick Insights, Statistics, Universal Interest | Tagged Alcohol, Alcohol Abuse, Alcohol and Dementia, Alcohol Consumption, Alcohol Dependence, Alcohol Misuse, Alcohol Services, Alcohol Use Disorders (AUDs), Alcohol Use Disorders and Cognitive Impairment Risk, Alcohol-Related Dementia, Alcohol-Related Harm, Alcoholic Dementia, BBC Health News, Behavioural Risk Factors, Binge Drinking, Bordeaux University Hospital, Campbell Family Mental Health Research Institute (Toronto), Canada, Cardiovascular Risk Factors (CVRF), Centre for Addiction and Mental Health (Toronto), Centre INSERM U1219-Bordeaux Population Health, Dalla Lana School of Public Health: University of Toronto, Dementia Risk Factors, Department of Psychiatry: University of Toronto, Early-Onset Dementia, Epidemiology, Epidemiology and Statistics, France, French National Hospital Discharge Database (Programme de Médicalisation des Systèmes d'Information), Germany, Harmful Alcohol Use, Infection Antimicrobials Modeling and Evolution: INSERM–Université Paris Diderot, INSERM, INSERM–Université Paris Diderot, Institute for Clinical Psychology and Psychotherapy: Technical University Dresden, Institute for Mental Health Policy Research (Toronto), Institute of Medical Science: University of Toronto, ISPED-Bordeaux School of Public Health, Lancet Public Health, Lifestyle Risk Factors, Medical Information Service (Bordeaux), Modifiable Risk Factors, Overlapping Risk Factors, Psychosocial and Lifestyle-Related Risk Factors, Public Health, Public Health Department (Bordeaux), Public Health Policy, Public Health Policy Against Alcohol-Related Harms, QalyDays Study Group, Risk Factors, Sorbonne Paris Cité, Technical University Dresden, Translational Health Economics Network (Paris), University of Bordeaux, University of Toronto, Vascular Cognitive Impairment, Vascular Dementia, Vascular Risk Factors | Leave a comment

Heading Footballs Associated With Dementia / CTE / Depression? (BBC News / Acta Neuropathologica / NHS Choices)

Posted on February 15, 2017 by Dementia and Elderly Care News

Summary Further evidence has emerged concerning a potential association between the practice of heading footballs and a heightened risk of long-term brain damage. This research is based on examination of the brains of small numbers of (mostly) professional footballers who … Continue reading →

Posted in BBC News, Depression, Diagnosis, For Researchers (mostly), In the News, NHS Digital (Previously NHS Choices), Quick Insights, Scotland, UK, Universal Interest, Wales | Tagged 1946 Birth Cohort, Acta Neuropathologica, Alan Shearer, Association Between Recent Concussion or Subconcussive Impacts and Depressive Symptoms in Male Australian Footballers, Australia, BBC Health News, BBC Tayside and Central Scotland, Behind the Headlines, Blood Organ and Tissue Donation, BMJ Open Sport and Exercise Medicine, Brain Bank Network (MRC), Brain Banking, Brain Donations, Cardiff University, CBD Solutions, Cefn Coed Hospital (Swansea), Chronic Traumatic Encephalopathy (CTE), Critical Appraisals, Dementia in Retired Association Football (Soccer) Players, Dementia Risk Factors, Dementia Risk Prevention, Dementia Risk Reduction, Department of Cellular Pathology: Cardiff University, Department of Clinical Neuroscience: UCL Institute of Neurology, Department of Molecular Neuroscience, Depressive Symptoms, Depressive Symptoms and Head-Related Trauma, Dr Charlotte Cowie: The Football Association (FA), Drake Foundation, Early-Onset Dementia, Edith Cowan University: Western Australia, England’s 1966 World Cup Winning Team, Exercise Medicine Research Institute: Edith Cowan University, Football Association, Football Association (FA), Football Brain Injury Research, Football Headers, Former Professional Soccer Players, Glasgow Brain Injury Research Group, Glasgow TBI Archive, Glasgow Traumatic Brain Injury Archive, Gordon Taylor: Professional Footballers' Association, Greater Glasgow and Clyde Health Board Bio-Repository, Heading Footballs Associated With Dementia / CTE: a New Category of Industrial Injury?, Heading Heavy Leather Footballs, Heading the Ball, Heading the Ball (Soccer / Soccer Practice), Institute for Health Research: University of Notre Dame Australia, Institute of Occupational Medicine, Jeff Astle: Former England Professional Football Player, Lifestyle Risk Factors, London School of Hygiene and Tropical Medicine (LSHTM), Male Semi-Professional West Australian Football League (WAFL) Players, Medical Research Council (MRC), Medical Research Council (UK), Mixed Brain Pathologies in Dementia, Modifiable Risk Factors, Neurodegenerative Disorders, Neurodegenerative Research, Neuropathology, Post-Mortem Studies, Professional Footballers, Professional Footballers' Association (PFA), QSBB: Queen Square Brain Bank for Neurological Disorders (UCL Institute of Neurology), Queen Mary University of London, Queen Square Brain Bank, Queen Square Brain Bank for Neurological Disorders, Queen's Square Brain Bank (London), Queens University Hospital Glasgow, Repetitive Mild Traumatic Brain Injury (rTBI), Reta Lila Weston Institute for Neurological Studies, Reta Lila Weston Institute for Neurological Studies: UCL Institute of Neurology, Retired Soccer Players With Dementia, Routine Soccer Heading, School of Health Sciences: University of Notre Dame Australia, School of Medical and Health Sciences: Edith Cowan University, Scotland, Semi-Professional Male Australian Football Players, Soccer Heading, Sports Medicine, Sub-Concussive Head Impacts, Traumatic Brain Injury, UCL Institute of Neurology, UK Brain Banks Network, University College London, University of Notre Dame (Australia), WAFL Injury Report Survey, WAFL Injury Report Survey (WIRS), West Australian Football League (WAFL), West Bromwich Albion, Western Australia | Leave a comment

Dementia Evidence Toolkit Launched (PSSRU at LSE / MODEM / NIHR)

Posted on August 9, 2016 by Dementia and Elderly Care News

Summary The new Dementia Evidence Toolkit has been built on a database of 3,000 journal articles and 700 reviews of research studies. This ambitious and world-leading online resource aims to offer a one-stop “hub” from which to access the latest evidence … Continue reading →

Posted in Acute Hospitals, Antipsychotics, Assistive Technology, Commissioning, Community Care, Delirium, Depression, End of Life Care, Falls, Falls Prevention, For Carers (mostly), For Doctors (mostly), For Nurses and Therapists (mostly), For Researchers (mostly), For Social Workers (mostly), Guidelines, Hip Fractures, Hypertension, In the News, Integrated Care, Management of Condition, Mental Health, Models of Dementia Care, National, NIHR, Non-Pharmacological Treatments, Nutrition, Pain, Parkinson's Disease, Patient Information, Person-Centred Care, Personalisation, Quick Insights, Standards, Systematic Reviews, Telecare, Telehealth, UK, Universal Interest | Tagged ADLs/IADLs, Advance Care Planning (ACP), Ageing Population, Alzheimer’s Disease, Care Home Admission Delay, Carer Burden, Carer Outcomes (Financial Burden and More), Carers’ Mental Health, Carers’ Physical Health, Choice in Health and Social Care, Co-Morbidities, Cognition, Cognitive Stimulation Therapy (CST), Community Settings, Consumer Experiences of Health and Social Care, Day Care, Dementia (General / Unspecified), Dementia Evidence Toolkit, Dementia Evidence Toolkit (MODEM): Evidence Database, Dementia Evidence Toolkit (MODEM): Evidence Summaries, Dementia Research, Dementia: What Works?, Depression and Anxiety, Early-Onset Dementia, Economic and Social Research Council (ESRC), Education and Staff Training, ESCR and NIHR’s Improving Dementia Care Initiative, Extra Care Housing, Fronto-Temporal Dementia, Global Leadership, Health and Social Care, Health and Social Care Services, Hospital Inpatient Care, Hospital Outpatient Care, Hospital Use Reduction, Huntingtons, Innovation in Health and Social Care, Instruments Measuring Carer Burden, Lewy Body Dementia, London School of Economics and Political Science (LSE), Long Term Residential Care Without Medically Trained Staff, LSE's Personal Social Services Research Unit (PSSRU), Maintenance Cognitive Stimulation Therapy (CST), Memory Clinics, Mild Cognitive Impairment (MCI), Modelling the Outcome and Cost Impacts of Interventions for Dementia Project (MODEM), MODEM, MODEM (Modelling the Outcome and Cost Impacts of Interventions for Dementia) Project, Museums, Music Therapy, National Institute for Health Research (NIHR), National Institute for Health Research (NIHR)’s Improving Dementia Care Initiative, Nursing Homes, Outcomes, Parkinson’s Dementia, Personal Social Services Research Unit (PSSRU), Personal Social Services Research Unit (PSSRU): London School of Economics and Political Science, Physical Health, Pick’s Disease, Prevention and/or Management of Co-morbidities, Primary Care, Professor Martin Knapp: Director of the Personal Social Services Research Unit at the London School of Economics and Political Science (LSE), PSSRU at LSE, Quality of Life of Carers, Quality Of Life Of Person With Dementia, Satisfaction With Care/services, Service Cost Reductions, Service Use, Specialist Dementia Centre Care / Memory Clinics, Staff Training, Staff Training in Assisted Living Residences (STAR), START: STrAtegies for RelaTives, STrAtegies for RelaTives (START), Supporting People with Dementia and Their Carers in Health and Social Care, Types of Dementia, Vascular Dementia, Workforce Training | Leave a comment

Spatial Navigation Tests For Disorientation May Identify Preclinical Alzheimer’s Disease? (BBC News / Science / JGCR / Brain)

Posted on October 26, 2015 by Dementia and Elderly Care News

Summary A German study indicates that persons with a high genetic risk of developing Alzheimer’s Disease might be identified early by monitoring their performance in tests involving navigation through a virtual maze. Full Text Link Reference Virtual reality maze ‘predicts … Continue reading →

Posted in BBC News, Diagnosis, For Doctors (mostly), For Researchers (mostly), In the News, International, Quick Insights, Universal Interest | Tagged APOE e4 Carriers, APOE-4 Allele, Apoe-ε4 Allele, APOE-ε4 Carriers, Apolipoprotein E (APOE) e4 Allele, Apolipoprotein E (Apoe)-ε4 Genotype, At-Genetic-Risk Alzheimer's Disease, BBC Health News, Behavioural Biomarkers, Big Data, Bonn, Brain (Journal), Center for Economics and Neuroscience: University of Bonn, Computer Games, Conversion to Dementia From Prodromal Disease, Dementia, Dementia Research, Department of Clinical Educational and Health Psychology: University College London, Department of Clinical Neurosciences: University of Cambridge, Department of Electrical Engineering: University College London, Department of Epileptology: University of Bonn, Department of Neuropsychology: Ruhr-University Bochum, Department of Psychiatry: University of Cambridge, Department of Psychology: Ulm University, Department of Psychology: University of Bonn, Diagnosis, Differential Diagnosis, Digital Diagnostic Tools, Disorientation, Donders Institute for Brain Cognition and Behaviour: Radboud University, Early Detection of Preclinical Disease, Early-Onset Alzheimer's Gene, Early-Onset Dementia, Entorhinal Cortex, Entorhinal Dysfunction in Adults at Genetic Risk for Alzheimer’s Disease, Gamification, German Center for Neurodegenerative Diseases (DZNE), German Centre for Neurodegenerative Diseases (Bonn), Germany, Germany. Department of Epileptology: University of Bonn, Grid-Cell-Like Representations, Grid-Cell-Like Representations in Adults at Genetic Risk for Alzheimer’s Disease, HTC Vive iVR Equipment, Information Technology, Institute of Cognitive Neuroscience: Ruhr-University Bochum, Institute of Cognitive Neuroscience: University College London, Journal of Geriatric Care and Research (JGCR), MRC Cognition and Brain Sciences Unit: University of Cambridge, Netherlands, Neurodegenerative Disease, Non-Invasive Biomarkers, Pre-Dementia (MCI), Preclinical Alzheimer's Disease, Preclinical Indicators and Dementia, Preclinical Indicators in Alzheimer's Disease, Prodromal Alzheimer's Disease, Radboud University, Risk Factors, Ruhr-University Bochum, Science (American Association for the Advancement of Science), Science Journal, Sea Hero Quest (SHQ) Game, Spatial Disorientation, Spatial Navigation Benchmarks, Spatial Navigation Tests of Disorientation, Ulm University, University College London, University of Bonn, University of Cambridge, Virtual Mazes | Leave a comment

Tag Archives: Early-Onset Dementia

More on the Possible Role of Neuroinflammation in Frontotemporal Dementia (Bazian / Brain)

Spatial Navigation Tests For Disorientation May Identify Preclinical Alzheimer’s Disease? (BBC News / Science / JGCR / Brain)

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