Tag Archives: Genetic Risk Factors

Healthy Lifestyles May Partially Help Offset Genetic Risk Factors for Dementia (BBC News / JAMA / Bazian)

Summary Persons in the UK Biobank study were followed over time to discover whether pursuing a healthy lifestyle (not smoking, regular physical activity, healthy diet and moderate alcohol consumption) might be associated with lower risk of developing dementia regardless of predisposing genetic risk factors. Statistically, favourable (“healthy”) lifestyles … Continue reading

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No Safe or Protective Level of Alcohol Consumption? (BBC News / Lancet)

Summary Light-to-moderate drinking increases blood pressure and the risk of stroke. “I have always been reasonably convinced that moderate alcohol consumption was protective for cardiovascular disease, but now I am having my doubts”. Professor David Spiegelhalter: Winton Professor for the … Continue reading

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Further Confirmation of the Benefits of Education for Cognitive Reserve? (NHS Choices / BMJ)

Summary A detailed investigation into modifiable risk factors for Alzheimer’s Disease provides further confirmation that levels of educational attainment are associated with a reduced risk of developing Alzheimer’s Disease. The following NHS Choices Behind the Headlines critical appraisal provides a … Continue reading

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Practical Tests to Determine Individual Biological Age? (BBC News / Genome Biology)

Summary Researchers at King’s College London (and internationally) have developed techniques promising to accurately measure a person’s “biological age”. People of the same chronological age vary in their rates of “biological ageing” – sometimes by margins of up to 15 … Continue reading

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Recent Reviews on the Association Between Type 2 Diabetes Mellitus and Dementia (Clinical Interventions in Aging / WJD)

Summary There is growing awareness of the relationships between Type 2 Diabetes mellitus, Alzheimer’s Disease and other forms of dementia. Full Text Link Reference Li, X. Song, D. [and] Leng, SX. (2015). Link between type 2 diabetes and Alzheimer’s Disease: … Continue reading

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A Question of Height: a New Dimension in Statistical and Genetic Risk Factors? (BBC News / NHS Choices / British Journal of Psychiatry / NEJM)

Summary A number of studies point to the unexpected potential influence of physical height in the risks of developing various diseases (which may or may not be related). It was found last year that decreasing height is associated statistically with … Continue reading

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Possible Link Between Alzheimer’s Disease and Schizophrenia? (BBC News / PNAS)

Summary A “weak spot” in the brain, which may be play some common role(s) underlying both Alzheimer’s Disease and schizophrenia, appears to have been identified using functional Magnetic Resonance Imaging (fMRI) brain scans. The brain area in question has been … Continue reading

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