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Tag Archives: Genetic Variants
Further Confirmation of the Benefits of Education for Cognitive Reserve? (NHS Choices / BMJ)
Summary A detailed investigation into modifiable risk factors for Alzheimer’s Disease provides further confirmation that levels of educational attainment are associated with a reduced risk of developing Alzheimer’s Disease. The following NHS Choices Behind the Headlines critical appraisal provides a … Continue reading
Posted in Community Care, For Carers (mostly), For Doctors (mostly), For Nurses and Therapists (mostly), For Researchers (mostly), In the News, International, NHS Digital (Previously NHS Choices), Non-Pharmacological Treatments, Quick Insights, Statistics, Universal Interest
Tagged Access to Education, Additional Year of Education Associated With an 11% Reduction in Risk of Alzheimer's Disease, Alzheimer’s Disease Genetics Consortium (ADGC), Bazian, Behind the Headlines, Benefits of Education, BMJ, BMJ Publishing Group Ltd, Cognitive Reserve, Cognitive Reserve Hypothesis, Cohorts for Heart and Aging Research in Genomic Epidemiology Consortium (CHARGE), CoSTREAM Consortium, Dementia Risk Factors, Department of Clinical Neurosciences: University of Cambridge, Department of Public Health and Primary Care: University of Cambridge, Educational Attainment, Epidemiology, Epidemiology and Statistics, European Alzheimer's Disease Initiative (EADI), European Union's Horizon 2020, Formal Education and Complex Work (Cognitive Reserve), Genetic and Environmental Risk in Alzheimer’s Disease Consortium (GERAD), Genetic Risk Factors, Genetic Variants, German Centre for Neurodegenerative Diseases, German Centre for Neurodegenerative Diseases (DZNE), Germany, Institute for Stroke and Dementia Research: Klinikum der Universität München, Institute of Environmental Medicine: Karolinska Institutet (Sweden), International Genomics of Alzheimer's Project (IGAP), International Genomics of Alzheimer’s Project, Karolinska Institute, Karolinska Institutet, Klinikum der Universität München, Ludwig-Maximilian University, Ludwig-Maximilians University ( Munich), Mendelian Randomisation, Modifiable Risk Factors, MRC Biostatistics Unit: University of Cambridge, Munich, Munich Cluster for Systems Neurology (SyNergy): Germany, Overlapping Risk Factors, Potentially Modifiable Socio-Environmental Risk Factors, Potentially Modifiable Socio-Environmental Risk Factors for Dementia, Risk Factors for Alzheimer's Diseease, Socio-Environmental Risk Factors, Socio-Environmental Risk Factors for Dementia, Stroke Research Group: University of Cambridge, Sweden, Sweden; Karolinska Institutet, Swedish Brain Foundation, Unit of Nutritional Epidemiology: Karolinska Institutet (Sweden), University of Cambridge
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Genetic Mutation Which Delays Alzheimer’s Disease? (NHS Choices / Molecular Psychiatry)
Summary A study of 71 persons from an extended family (comprising around 5,000 people) in northern Colombia, who carry a mutation in a gene called PSEN1 (the so-called the Paisa mutation, which causes a rare, severe form of early-onset Alzheimer’s disease), … Continue reading
Posted in For Researchers (mostly), In the News, International, NHS Digital (Previously NHS Choices), Quick Insights, Statistics, Universal Interest
Tagged Alzheimer's Disease Susceptibility Genes, ApoE e4 Allele, APOE-4 Allele, Apoe-ε4 Allele, Apolipoprotein E (APOE) e4 Allele, Australia, Australian National University, Behind the Headlines, Biomolecular Resource Facility: Australian National University, Colombia, Department of Genome Sciences: Australian National University, Early Mammalian Development Laboratory: Australian National University, Early-Onset Alzheimer's Gene, Flinders University (Australia), Genetic Research, Genetic Susceptibility Loci, Genetic Triggers, Genetic Variants, Genetic Variation (APOE*E2 Allele), Genetics, Genetics of Alzheimer's Disease, Genome Diversity and Health Group: Australian National University, Genomics and Predictive Medicine Group: Australian National University, Germany, Hamburg, Hereditary Form of Early-Onset Alzheimer's Disease, Institute of Neuropathology: University Medical Center Hamburg-Eppendorf, John Curtin School of Medical Research: Australian National University, Mental Health Research Center at Eastern State Hospital: University of Kentucky, Molecular Psychiatry (Journal), Nathan Kline Institute for Psychiatric Research, Nathan Kline Institute for Psychiatric Research (USA), Neurodegeneration, Neurodegenerative Disease Research, Neurodegenerative Diseases, Neuroscience Research Group: University of Antioquia, New York University, Northern Colombia, NYU Child Study Center: NYU Langone Medical Center, NYU Langone Medical Center, Paisa Mutation: Mutated PSEN1 Gene, Presenilin 1 (PSEN1), Presenilin 1 Mutation (PSEN1), PSEN1 E280A Alzheimer's Disease, PSEN1 E280A Carriers, PSEN1: Presenilin 1 Mutation, Rare Unusual Hereditary Form of Alzheimer’s Disease, Research School of Biology: Australian National University, School of Medicine: Flinders University, South Australian Health and Medical Research Institute and Department of Psychiatry: Flinders University, University Medical Center Hamburg-Eppendorf, University of Antioquia (Colombia), University of Antioquia in Colombia, University of Kentucky, USA
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Genetic / Biological Foundations of Mental Processing Speed Discovered? (BBC News / Molecular Psychiatry)
Summary A large international epidemiological study of data from 30,000 people may have identified underlying genetic variants linked to individual differences in the ability to process information. Genetic differences might explain why some people are quicker thinkers in middle age … Continue reading
Posted in BBC News, For Doctors (mostly), For Researchers (mostly), In the News, International, Quick Insights, Scotland, UK, Universal Interest
Tagged Australia, BBC Health News, CADM2 Gene, Cell Adhesion Molecule Two (CADM2) Gene, CHARGE (Cohorts for Heart and Aging Research in Genomic Epidemiology) Consortium, Croatia, Digit Symbol Substitution Test (DSST), DTNBP1, Edinburgh University, Executive Function and Processing Speed, Finland, Gamma-Aminobutyric Acid (GABA) Transport, Genetic / Biological Foundations of Mental Processing Speed, Genetic Research, Genetic Variants, Genetics, Genome-Wide Association Studies (GWAS), Glutamate Signalling, Holland, Letter Digit Coding Test (LDCT), Letter-Digit Substitution Task (LDST), Mental Processing Speed, Molecular Psychiatry (Journal), Neuron Cell-Cell Adhesion, Quick Thinkers, Scotland, Single Nucleotide Polymorphisms (SNPs), Stroop Card 2 (Colour Card), Stroop Card 3 (Colour Word Card), Symbol Digit Modalities Test (SDMT), Thinking Efficiency, Thinking Speed, Trail Making Test Part A (Trail A), Trail Making Test Part B (Trail B), TRIB3, WDR72 Gene
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Alzheimer’s Disease Facts and Figures 2014 (Alzheimer’s Association / Lancet)
Summary A recent report from the US Alzheimer’s Association provides a statistical summary of United States data concerning Alzheimer’s Disease. While this report is geared primarily to the United States it is of wider interest internationally for a review of … Continue reading
Posted in For Doctors (mostly), For Nurses and Therapists (mostly), For Researchers (mostly), International, Mental Health, Models of Dementia Care, Patient Care Pathway, Statistics, Systematic Reviews, Universal Interest
Tagged Alzheimer's Association, Alzheimer’s Disease Facts and Figures 2014, ApoE and Genetics of Alzheimer's Disease, Attitudes About Alzheimer’s Disease and Dementia (US), Burden of Alzheimer’s Disease, Deaths from Alzheimer’s Disease (US), Duration of Caregiving (US), Epidemiology, Epidemiology and Statistics, Genetic Triggers, Genetic Variants, Geriatric Health Care Professionals in the United States, Home Health Aids (US), Hospice Care, Incidence of Alzheimer’s Disease, Lancet, Lifetime Risk of Alzheimer’s Disease, Long-Term Care (LTC), Modern Diagnosis of Alzheimer’s Disease: Proposed Criteria, Morbidity, Mortality, Paid Caregivers, Prevalence of Alzheimer’s Disease and Other Dementias, Prevalence of Dementia, Public Health Impact of Deaths from Alzheimer’s Disease (US), Risk Factors, Risk Factors for Alzheimer's Diseease, Sandwich Generation Caregivers, Treatment of Alzheimer's Disease, United States, Unpaid Caregivers (Carers), Unpaid Carers, USA, Women and Alzheimer’s Disease
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