Tag Archives: Icahn School of Medicine at Mount Sinai

Big Data Portal for Alzheimer’s Dementia Drug Discovery (NIH / Synapse AMP-AD)

Posted on March 8, 2015 by Dementia and Elderly Care News

Summary The National Institutes of Health (NIH) in the USA has opened a public-private partnership online resource to facilitate neurodegenerative research and drug development. The launch of the Alzheimer’s Big Data Portal provides an open-source “public knowledge portal” for the … Continue reading →

Posted in Charitable Bodies, For Doctors (mostly), For Researchers (mostly), In the News, International, Pharmacological Treatments, Quick Insights | Tagged Academia-Industry Partnerships, Academia-Industry Synergies, Accelerating Alzheimer's Research and Drug Development, Accelerating Medicine Partnership for Alzheimer's Disease (NIA-AMP AD) Target Discovery and Preclinical Validation Project, Accelerating Medicines Partnership (AMP), Accelerating Medicines Partnership-Alzheimer's Disease (AMP-AD), Alfred P. Sloan Foundation, Alzheimer’s Disease Biomarkers, Alzheimer’s Disease Cooperative Study, Alzheimer’s Disease Neuroimaging Initiative (ADNI), AMP-AD Program, Big Data, Big Data Portal for Alzheimer’s Dementia Drug Discovery, Big Pharma, Biomarkers, Biopharmaceutical Companies, Broad Institute of MIT and Harvard, Collaboration, Collaborative Drug Discovery Programmes, Collaborative Projects, Cross-Sector Partnerships, Dementia Research, Drug Development for Alzheimer's Disease, Drug Discovery Programmes, Drug Identification, Drug Target Validation, Drug-Development Pipeline, Drugs for Treatment of Alzheimer’s Disease, Emory University, Foundation for the NIH (FNIH), Genetic Research, Genetic Testing, Genetic Triggers, Genetics of Alzheimer's Disease, Global Open Data Initiative, Human Epigenome Atlas, Icahn School of Medicine at Mount Sinai, Institute for Systems Biology (Seattle), International Alzheimer's Disease Research Portfolio (IADRP), International Collaborations, International Organisations, International Programmes, Market Failure (Dementia Research and Drug Development), Mayo Clinic in Jacksonville, Medical Research, Multidisciplinary Research Teams, National Institutes of Health (NIH), Neurodegeneration, Neurodegenerative Disease Research, Neurodegenerative Diseases, NIA Genetics of Alzheimer’s Data Storage Site (NIAGADS), NIH Big Data to Knowledge (BD2K) Initiative, NIH Network for Excellence in Neuroscience Clinical Trials, Non-Profit Collaborations, Novel Targets in Neurodegeneration, Open Data, Open Data and Big Data, Open Data in Health and Social Care, Open Data Learning Capacity and Culture, Open Data: Unlocking Innovation, Open Source Solutions, Pharmaceutical Industry, Pharmacological Research, Potential of Open Data in Health and Social Care, Pre-Competitive Collaboration, Precision Medicine Initiative, Preclinical Biomarkers in Alzheimer's Disease, Public-Private Partnership (PPP), Public-Private Partnerships, Research and Development, Research and Innovation, Research Commitment, Research Consortia, Research Culture, Research Networks, Research Programmes, Roadmap Epigenomics Project, Rush University Medical Center: Chicago, Sage Bionetworks, Synapse, Synapse Access and Compliance Team, Target Discovery and Preclinical Validation, Technology Transfer, Temporal Evolution of Alzheimer’s Disease Biomarkers, Therapeutic Target(s): Identification, Translational Research, Transparency and Open Data, United States, University of California, University of Florida, US National Institute of Aging, US National Institutes of Health (NIH), USA | Leave a comment

Primary Age Related Tauopathy (PART): A New Type / Cause of Cognitive Impairment?

Posted on November 18, 2014 by Dementia and Elderly Care News

Summary The authors of this article propose the introduction of a new term to describe a pathology found to be commonly present in the brains of aged persons; namely “Primary Age-Related Tauopathy (PART). Autopsy studies indicate brains with neurofibrillary tangles … Continue reading →

Posted in Diagnosis, For Doctors (mostly), For Nurses and Therapists (mostly), For Researchers (mostly), In the News, International, Quick Insights, Systematic Reviews, Universal Interest | Tagged Acta Neuropathologica, Age and Ageing, Age-Related Pathologies, Ageing, Ageing and Dementia, Ageing Population, Amnestic MCI, Amnestic Mild Cognitive Impairment (a-MCI), Amnestic Mild Cognitive Impairment (aMCI), Banner Sun Health Research Institute, Biomarkers, Boston University, Civin Laboratory for Neuropathology: Banner Sun Health Research Institute, Cognitive Ageing, Cognitive Impairment, Columbia University, Columbia University Medical Center, Common Pathology Associated With Human Ageing, Department of Neuroscience: Mayo Clinic, Department of Pathology and Cell Biology: Columbia University Medical Center, Department of Pathology and Immunology: Washington University School of Medicine, Department of Physiology and Sanders-Brown Center on Aging: University of Kentucky, Departments of Pathology (Neuropathology) and Neurological Sciences: Rush University Medical Center, Division of Neuropathology: University of Pennsylvania, Emory University School of Medicine (Atlanta), Fishberg Department of Neuroscience and Friedman Brain Institute, Genetics and Pathology: Uppsala University, Harvard Medical School, Human Ageing Process, Icahn School of Medicine at Mount Sinai, Institute for Ageing and Health: Newcastle University, Institute of Clinical Neurobiology (Vienna), Kanazawa University Graduate School of Medical Sciences, Massachusetts General Hospital, Mayo Clinic, Mild Cognitive Impairment (MCI), Neurodegeneration, Neurodegenerative Disease Research, Neurodegenerative Diseases, Neurodegenerative Research, Neurofibrillary Tangles, Neurofibrillary Tangles (NFTs), Neuropathologic Disorders, Neuropathology, New York University School of Medicine, Newcastle University, NFT+/Aβ- Brains (Neurofibrillary Tangles Without Amyloid [Aβ] Plaques), Northwestern Cognitive Neurology and Alzheimer Disease Center: Northwestern University Feinberg School of Medicine, Northwestern University Feinberg School of Medicine, Oregon Health Sciences University, PART: Primary Age-Related Tauopathy, Primary Age Related Tauopathy (PART), Rush University Medical Center (US), Rush University Medical Center: Chicago, Sanders-Brown Center on Aging, Screening for Cognitive Impairment, Tau, Tau Pathology, Tau Protein, Taub Institute for Research on Alzheimer's Disease and the Aging Brain, Tauopathy, Tokyo Metropolitan Geriatric Hospital, University of British Columbia, University of California, University of Iowa Hospitals and Clinics, University of Kentucky, University of Pennsylvania, University of Pennsylvania Perelman School of Medicine, University of Pittsburgh Medical Center, University of São Paulo, University of Texas Southwestern Medical School, University of Ulm, University of Washington, Uppsala University, VA Medical Center and Boston University School of Medicine, Washington University School of Medicine | Leave a comment

Dementia Risk From Cooked Meats? (BBC News / NHS Choices / PNAS)

Posted on February 26, 2014 by Dementia and Elderly Care News

Summary Research at the Icahn School of Medicine at Mount Sinai (New York), investigating the effect of Advanced Glycation End (AGEs) on mice and people, suggests that browning meat produces chemicals which may increase the risk of developing dementia. Mice … Continue reading →

Posted in Animal Studies, BBC News, For Carers (mostly), For Doctors (mostly), For Nurses and Therapists (mostly), For Researchers (mostly), In the News, International, NHS Digital (Previously NHS Choices), Universal Interest | Tagged Advanced Glycation End (AGE), Amyloid Beta, Amyloid Beta Protein, Amyloid Proteins, Amyloid-β (Aβ), Amyloid-β (Aβ) Accumulation, Australasia, BBC Health News, Behind the Headlines, Beta-Amyloid, Beta-Amyloid Plaques, Broiling Meats, Browning Meat, Cooked Meats, Critical Appraisals, Department of Medicine: University of Pavia, Diabetes, Diet, Diet and Dementia, Dietary Choices, Food Advanced Glycation End Products (AGEs), Frying Meats, Frying Pans, George Institute: Sydney, Grilling Meats, Grills, High-AGEs Diets, Icahn School of Medicine at Mount Sinai, Insulin Sensitivity, Italy, β-amyloid, β-amyloid Deposition, Metabolic Syndrome, Methyl-Glyoxal Derivatives (MG), Mice, Modifiable Risk Factors, NAD+, Oral Glycotoxins, Ovens, Oxidation, PNAS, Proceedings of the National Academy of Sciences (PNAS), Proceedings of the National Academy of Sciences of the United States of America (PNAS), Risk Factors, Risk Factors for Alzheimer's Diseease, Roasting Meats, Searing Meats, SIRT1, SIRT1 Deficiency, UConn Center on Aging: University of Connecticut Health Center, United States, University of Connecticut, University of Connecticut Health Center, University of Pavia, US National Institute of Health | Leave a comment

Tag Archives: Icahn School of Medicine at Mount Sinai

Dementia Risk From Cooked Meats? (BBC News / NHS Choices / PNAS)

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