Tag Archives: Immune System and Neurodegenerative Diseases

Mid-Life Blood Test for Inflammation May Predict Later-Life Dementia Risk? (NHS Choices / Neurology)

Posted on November 5, 2017 by Dementia and Elderly Care News

Summary Higher inflammatory marker scores in middle age, based on five blood-based markers of inflammation (fibrinogen, albumin, von Willebrand factor, factor VIII and white blood cell count) appear to be associated with reduced brain volume (thought to be neurodegenerative “shrinkage”) … Continue reading →

Posted in For Doctors (mostly), For Nurses and Therapists (mostly), For Researchers (mostly), In the News, International, NHS Digital (Previously NHS Choices), Quick Insights, Universal Interest | Tagged AD Signature Region Volume (Shrinkage), Albumin, ARIC Study: Atherosclerosis Risk in Communities, Atherosclerosis Risk in Communities (ARIC) Study, Baylor College of Medicine, Bazian, Behind the Headlines, Biomarker Development, Biomarkers, Biomarkers for Inflammation, Biomarkers Research Programmes, Blood-Based Biomarkers, Blood-Based Biomarkers of Pre-Symptomatic Alzheimer’s Disease, Brain Shrinkage, Brain Volume, Center for Cardiovascular Disease Prevention: Houston Methodist DeBakey Heart and Vascular Center, Critical Appraisals, Department of Medicine: University of Mississippi Medical Center, Departments of Neurology and Epidemiology: Johns Hopkins University School of Medicine, Departments of Neurology and Radiology: Mayo Clinic (Rochester), Division of Epidemiology and Community Health: University of Minnesota, Factor VIII, Fibrinogen, Hippocampal Volume, Hippocampal Volume (Memory Related), Hippocampus (Shrinkage in Late Adulthood), Houston Methodist DeBakey Heart and Vascular Center (Texas), Immune System, Immune System and Neurodegenerative Diseases, Inflammation, Inflammation and Neurodegenerative Diseases, Inflammatory Response, Johns Hopkins University School of Medicine, Mayo Clinic, Mayo Clinic: Rochester, Neurodegenerative Disease Research, Neurodegenerative Diseases, Neurodegenerative Disorders, Neurology (Journal), Occipital Lobe Volume (Shrinkage), Plasma Biomarkers, Preclinical Biomarkers and Dementia, Preclinical Biomarkers in Alzheimer's Disease, School of Public Health: University of Minnesota, Section of Cardiology: Baylor College of Medicine, Section of Cardiology: Baylor College of Medicine. Baylor College of Medicine, Systemic Inflammation, Systemic Inflammation and Neurodegeneration, United States, University of Minnesota, University of Mississippi Medical Center, University of Mississippi Medical Centre, US National Heart Lung and Blood Institute, USA, von Willebrand Factor, White Blood Cell Count | Leave a comment

Early Research on Stress and Social Disadvantage as Potential Risk Factors (BBC News / AAIC)

Posted on July 20, 2017 by Dementia and Elderly Care News

Summary Early research findings presented at the Alzheimer’s Association International Conference in London suggest that stressful life events, and more generally the chronic stress of enduring social deprivation life-long, may age the brain. The researchers claim that extremely stressful experiences … Continue reading →

Posted in BBC News, Charitable Bodies, Community Care, For Nurses and Therapists (mostly), For Researchers (mostly), For Social Workers (mostly), In the News, International, Quick Insights, UK, Universal Interest | Tagged 2017 Alzheimer’s Association International Conference (AAIC®2017), African Americans, Alzheimer’s Association AAIC Press Office, Alzheimer’s Association International Conference (AAIC®2017), Dementia Risk Factors, Dementia Risk Prevention, Dementia Risk Reduction, Dementia Risk Reduction and Prevention, Environmental Risk Factors, Epidemiology, Epidemiology and Statistics, Ethnicity, Health Determinants, Health Improvement, Health Inequalities, Health Policy, Immune System, Immune System and Neurodegenerative Diseases, Improving Local Public Health, Improving Public Health, Inflammation, Inflammation and Neurodegenerative Diseases, Inflammatory Response, Lifestyle Risk Factors, Modifiable Risk Factors, Necroptosis, Neurodegenerative Disease Research, Neurodegenerative Diseases, Neurodegenerative Disorders, Neuroinflammation, Overlapping Risk Factors, Potentially Modifiable Socio-Environmental Risk Factors, Prevention, Prevention Agenda, Prevention of Dementia, Reducing Health Inequalities, Risk Factors, Social Epidemiology, Socio-Environmental Risk Factors, Stressful Life Experiences, University of Wisconsin School of Medicine, University of Wisconsin-Milwaukee | Leave a comment

Patterns in the Development of Alzheimer’s Disease? (NHS Choices / Science Advances)

Posted on August 26, 2016 by Dementia and Elderly Care News

Summary Patterns of gene activity (gene expression) in specific areas of the brain may help explain why Alzheimer’s Disease tends to start in certain regions before spreading further through the brain. “ …those regions of the brain in which tissues … Continue reading →

Posted in For Doctors (mostly), For Researchers (mostly), In the News, NHS Digital (Previously NHS Choices), Quick Insights, UK, Universal Interest | Tagged Abnormal Proteins, Abnormal Proteins (Tau), Aβ Accumulation, Aβ Seeds, Aβ-Plaques, Allen Brain Atlas, Allen Brain Atlas: 3-D Digital Images of Gene Expression, Amyloid and Tau Imaging, Amyloid Beta Protein, Amyloid-β (Aβ), Amyloid-β (Aβ) Accumulation, Behind the Headlines, Braak Staging, Braak Staging of Alzheimer’s Disease, Department of Chemistry: University of Cambridge, Department of Molecular Biosciences: Northwestern University, Histopathological Staging of Alzheimer's Disease, Immune System, Immune System and Neurodegenerative Diseases, Levels of Genes Associated with Inflammation Mapped to Brain Areas, Mapping Brain Areas Affected in Early-Stage Alzheimer's Disease, Mapping Brain Areas Genetically Primed For Protein Overgrowth, Mapping Brain Areas Showing First Signs of Alzheimer's Disease, Mapping Brain Areas Susceptible to Protein Growth Due to Levels of Protein Expression, Mapping Brain Areas Vulnerable to Protein Overgrowth, Mapping Brain Areas: Allen Brain Atlas, Neurofibrillary Tangles, Northwestern University (USA), Pathological Staging, Patterns in the Development of Alzheimer’s Disease, Protein Aggregation, Protein Homeostasis, Protein Misfolding, Protein Overgrowth, Protein Plaques, Protein Seeds (Amyloid), Science Advances, Tau Aggregation, Tau Tangles, Tissue-Specific Progression of Alzheimer's Disease, University of Cambridge, USA, Vulnerability Patterns for Alzheimer's Disease | Leave a comment

More on Inflammation, the Immune System and Neurodegenerative Diseases (NHS Choices / Frontiers in Neuroscience / BBC News)

Posted on June 19, 2016 by Dementia and Elderly Care News

Summary A review article was published last month, covering evidence suggesting that the body’s innate immune system may be involved in neurodegenerative conditions, including Alzheimer’s Disease and Parkinson’s Disease, associated with a cascade of progressive damage to brain cells. Further … Continue reading →

Tag Archives: Immune System and Neurodegenerative Diseases

Patterns in the Development of Alzheimer’s Disease? (NHS Choices / Science Advances)

More on Inflammation, the Immune System and Neurodegenerative Diseases (NHS Choices / Frontiers in Neuroscience / BBC News)

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