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Tag Archives: Immune System and Neurodegenerative Diseases
Early Research on Stress and Social Disadvantage as Potential Risk Factors (BBC News / AAIC)
Summary Early research findings presented at the Alzheimer’s Association International Conference in London suggest that stressful life events, and more generally the chronic stress of enduring social deprivation life-long, may age the brain. The researchers claim that extremely stressful experiences … Continue reading
Posted in BBC News, Charitable Bodies, Community Care, For Nurses and Therapists (mostly), For Researchers (mostly), For Social Workers (mostly), In the News, International, Quick Insights, UK, Universal Interest
Tagged 2017 Alzheimer’s Association International Conference (AAIC®2017), African Americans, Alzheimer’s Association AAIC Press Office, Alzheimer’s Association International Conference (AAIC®2017), Centre for the Study of Social Cohesion: University of Oxford, Cortisol, Dementia Risk Factors, Dementia Risk Prevention, Dementia Risk Reduction, Dementia Risk Reduction and Prevention, Environmental Risk Factors, Epidemiology, Epidemiology and Statistics, Ethnicity, Health Determinants, Health Improvement, Health Inequalities, Health Policy, Immune System, Immune System and Neurodegenerative Diseases, Improving Local Public Health, Improving Public Health, Inflammation, Inflammation and Neurodegenerative Diseases, Inflammatory Response, Lifestyle Risk Factors, Modifiable Risk Factors, Necroptosis, Neurodegenerative Disease Research, Neurodegenerative Diseases, Neurodegenerative Disorders, Neuroinflammation, Overlapping Risk Factors, Potentially Modifiable Socio-Environmental Risk Factors, Prevention, Prevention Agenda, Prevention of Dementia, Reducing Health Inequalities, Risk Factors, Social Epidemiology, Socio-Environmental Risk Factors, Stressful Life Experiences, University of Wisconsin School of Medicine, University of Wisconsin-Milwaukee
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Patterns in the Development of Alzheimer’s Disease? (NHS Choices / Science Advances)
Summary Patterns of gene activity (gene expression) in specific areas of the brain may help explain why Alzheimer’s Disease tends to start in certain regions before spreading further through the brain. “ …those regions of the brain in which tissues … Continue reading
Posted in For Doctors (mostly), For Researchers (mostly), In the News, NHS Digital (Previously NHS Choices), Quick Insights, UK, Universal Interest
Tagged Abnormal Proteins, Abnormal Proteins (Tau), Aβ Accumulation, Aβ Seeds, Aβ-Plaques, Allen Brain Atlas, Allen Brain Atlas: 3-D Digital Images of Gene Expression, Amyloid and Tau Imaging, Amyloid Beta Protein, Amyloid-β (Aβ), Amyloid-β (Aβ) Accumulation, Behind the Headlines, Braak Staging, Braak Staging of Alzheimer’s Disease, Department of Chemistry: University of Cambridge, Department of Molecular Biosciences: Northwestern University, Histopathological Staging of Alzheimer's Disease, Immune System, Immune System and Neurodegenerative Diseases, Levels of Genes Associated with Inflammation Mapped to Brain Areas, Mapping Brain Areas Affected in Early-Stage Alzheimer's Disease, Mapping Brain Areas Genetically Primed For Protein Overgrowth, Mapping Brain Areas Showing First Signs of Alzheimer's Disease, Mapping Brain Areas Susceptible to Protein Growth Due to Levels of Protein Expression, Mapping Brain Areas Vulnerable to Protein Overgrowth, Mapping Brain Areas: Allen Brain Atlas, Neurofibrillary Tangles, Northwestern University (USA), Pathological Staging, Patterns in the Development of Alzheimer’s Disease, Protein Aggregation, Protein Homeostasis, Protein Misfolding, Protein Overgrowth, Protein Plaques, Protein Seeds (Amyloid), Science Advances, Tau Aggregation, Tau Tangles, Tissue-Specific Progression of Alzheimer's Disease, University of Cambridge, USA, Vulnerability Patterns for Alzheimer's Disease
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More on Inflammation, the Immune System and Neurodegenerative Diseases (NHS Choices / Frontiers in Neuroscience / BBC News)
Summary A review article was published last month, covering evidence suggesting that the body’s innate immune system may be involved in neurodegenerative conditions, including Alzheimer’s Disease and Parkinson’s Disease, associated with a cascade of progressive damage to brain cells. Further … Continue reading
Posted in For Doctors (mostly), For Nurses and Therapists (mostly), For Researchers (mostly), In the News, International, NHS Digital (Previously NHS Choices), Parkinson's Disease, Quick Insights, Systematic Reviews, Universal Interest
Tagged Aging Cell (Journal), AGS: Aicardi-Goutieres Syndrome, ALS: Amyotrophic Lateral Sclerosis, Apoptosis, Australia, Australian National Health and Medical Research Council, Autophagy, BBC Health News, Behind the Headlines, Birmingham, Brain and Immune System, Brain Inflammation, Cascade of Inflammation and Brain Cell Death, CD33, Cellular Clearance Mechanisms Implicated in Innate Surveillance Response, Centre for Molecular Pathology: University of Adelaide, Centre of Human and Aerospace Physiological Sciences: King's College London, Colony-Stimulating Factor 1 Receptor (CSF1R), CSF1R Receptor, Cycling, dAMPs: Damage Associated Molecular Patterns, DAMPs: Danger Associated Molecular Patterns, Danger (DAMP) and Damage (dAMP) Associated Molecular Patterns, Danger Associated Molecular Patterns (DAMPs), Department of Genetics and Evolution: University of Adelaide, Discipline of Psychiatry: University of Adelaide, Drosomycin, Endoplasmic Reticulum Associated Degradation (ERAD), Endoplasmic Reticulum Stress Unfolded Protein Response, Exercise in Old Age and Prevention of Immune System Decline, Frontiers in Neuroscience, FTD: Fronto-Temporal Dementia, Granulophagy, Heat Shock Response (HSR), HMG-B1, immune Senescence, Immune System, Immune System and Neurodegenerative Diseases, Immunesenescence, Inflammation, Inflammation and Neurodegenerative Diseases, Inflammatory Response, Innate Surveillance Mediated Cell Death, Institute of Inflammation and Ageing: University of Birmingham, Kings College London, MDA-5 (IFIH1), Microglia, Microglial Multiplication, Microglial Proliferation, Mitochondrial Unfolded Protein Response (UPRmt), Modification of CSF1R Activation to Reduce Microglial Activation, MRC-Arthritis Research UK Centre for Musculoskeletal Ageing Research: University of Birmingham, MyD88, National Ataxia Foundation, Necroptosis, Neurodegenerative Disease Research, Neurodegenerative Diseases, Neurodegenerative Disorders, Neuroimmunology, Neuroinflammation, Neuroinflammatory and Neurodegenerative Diseases, NIHR Biomedical Research Centre in Inflammation: University Hospital Birmingham, Nonsense Mediated Decay (NMD), Other-Optosis, PAMP: Pathogen Associated Molecular Pattern, Pathogen Associated Molecular Patterns (PAMPs), Pattern Recognition Receptors (PRRs), Physical Activity Improves Immune System, Programmed Cell Death, PRR: Pattern Recognition Receptor, Pyroptosis, RLR: RIG-I-Like Receptor, RNA Exosome (SKIV2L), Robinson Research Institute: University of Adelaide, School of Biological Sciences: University of Adelaide, School of Medicine: University of Adelaide, School of Paediatrics and Reproductive Health: University of Adelaide, Sentinels (Pattern Recognition Receptors: PRRs), Serpin5, The Enemy Within: Innate Immune Surveillance System (Hypothesis), Thymic Output, Thymus, TLR4, TLR: Toll-Like Receptor, TNF, Toll and Spätzle, TREM2, Ubiquitin-Proteosome System (UPS), Unfolded Protein Response (UPR), University Hospital Birmingham, University Hospital Birmingham NHS Foundation Trust, University of Adelaide, University of Birmingham, XBP-1
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