Tag Archives: Inflammation

More on the Possible Role of Neuroinflammation in Frontotemporal Dementia (Bazian / Brain)

Posted on March 22, 2020 by Dementia and Elderly Care News

Summary Inflammation in the brain has been found to be present alongside (“co-localised” with) protein clusters in patients with frontotemporal dementia, suggesting that neuroinflammation may be involved as a potential cause of frontotemporal dementia. “The researchers found that both the … Continue reading →

Posted in For Doctors (mostly), For Nurses and Therapists (mostly), For Researchers (mostly), In the News, International, NHS Digital (Previously NHS Choices), Quick Insights, UK, Universal Interest | Tagged Association of British Neurologists, Bazian, Behavioural Frontotemporal Dementia (bvFTD), Behavioural Variant Frontotemporal Dementia (bvFTD), Behind the Headlines, Biomarker Development, Biomarkers, Biomarkers for Inflammation, Brain (Journal), Brain Autopsies, Brain Inflammation, C-PK-11195, C-PK-11195 (Biomarker for Inflammation), Cambridge Brain Bank, Cambridge Centre for Parkinson-Plus, Cambridge University Hospitals NHS Foundation Trust, Consiglio Nazionale delle Ricerche (CNR), Critical Appraisals, Degenerative Tauopathy, Department of Clinical Neurosciences: Cambridge University, Department of Neurology: Walton Centre (Liverpool), Department of Pathology: Cambridge University Hospitals NHS Foundation Trust, Department of Psychiatry: University of Cambridge, Division of Anaesthesia: University of Cambridge, Early-Onset Dementia, F-AV-1451, F-AV-1451 (Biomarker for Protein Clusters), Fronto-Temporal Dementia (FTD), Frontotemporal Dementia, Frontotemporal Dementia (FTD), FTD: Fronto-Temporal Dementia, FTLD-Pick’s, FTLD-TDP (A), FTLD-TDP (C), FTLD-TDP (Types A and C), FTLD-TDP-43, Immune Cells (Microglia), Inflammation, Inflammation and Neurodegenerative Diseases, Istituto di Bioimmagini e Fisiologia Molecolare (IBFM): Consiglio Nazionale delle Ricerche (CNR), Italy, Lundbeck Foundation (Denmark), Medical Research Council (MRC), Medical Research Council Cognition and Brain Sciences Unit: University of Cambridge, Microglia, Monoamine Oxidase (MAO), National Institute of Health Research, Neurodegenerative Disease Research, Neurodegenerative Diseases, Neurodegenerative Disorders, Neuroinflammation, Neuroinflammation and Frontotemporal Dementia, Neuroinflammation and Protein Aggregation, Neuromelanin, NIHR Dementias and Neurodegenerative Diseases Research Network, Non-Amyloid-β Protein Aggregation, Non-Fluent Variant Primary Progressive Aphasia (nfvPPA), Patrick Berthoud Charitable Trust, PET Scans, Pick’s Disease (Frontotemporal Dementia), Positron Emission Tomography (PET), Protein Aggregation, Protein Clusters, Semantic Variant Primary Progressive Aphasia (svPPA), Tauopathy, TDP-43, TDP-43 Pathology, TDP-43 Protein, TDP-43 Proteinopathy, University of Cambridge, Variants of Primary Progressive Aphasia (PPA), Wellcome Trust, Wolfson Brain Imaging Centre: University of Cambridge | Leave a comment

Dementia Research Centre in Wales (BBC News)

Posted on October 26, 2018 by Dementia and Elderly Care News

Summary A brief piece, from BBC News, on the work and aims of the £20 million Dementia Research Institute at Cardiff University. Full Text Link Reference Clarke, O. (2018). Fruit flies’ brains studied to help crack dementia. London: BBC Health … Continue reading →

Posted in BBC News, For Researchers (mostly), In the News, National, Quick Insights, UK, Universal Interest, Wales | Tagged BBC Health News, BBC Wales News, Biomarkers Research Programmes, Bioscience Careers, Brain Research Imaging Centre at Cardiff University (CUBRIC), Cardiff University, Dementia Action Plan for Wales: 2018-2022, Dementia Research, Dementia Research Careers, Dementia Research Institute (Cardiff), Dementia Research Institute (DRI), Dementia Research Institute at Cardiff University, Drosophila melanogaster, Fruit Flies, Genetic Research, Immune Pathways and Stem Cell (iPSC) Models of Neurodegenerative Disease, Immunology, Inflammation, Inflammatory Response, National Dementia Vision for Wales, Neurodegenerative Disease Research, Neurodegenerative Diseases, Neurodegenerative Disorders, Neurodegenerative Research, Neurodevelopmental Disorders: Abnormal Brain Development, Neuroinflammation, Neuroinflammation Research Cluster, Neuroscience, Research and Development, Research and Innovation, Research Careers, Research Commitment, Research Culture, Research Funding, Transgenic Drosophila, Vaughan Gething: Welsh Health Secretary, Welsh Government, Welsh Government Dementia Oversight of Implementation and Impact Group (DOIIG) | Leave a comment

Mediterranean Diets: Good for Mental Health? (BBC News / Molecular Psychiatry / NHS Choices)

Posted on September 26, 2018 by Dementia and Elderly Care News

Summary Mediterranean diets may help to prevent depression, according to a new meta-analysis of 41 earlier studies. More research is needed to confirm this suspected link. Full Text Link Reference Mediterranean diet ‘may help prevent depression’. London: BBC Health News, … Continue reading →

Posted in BBC News, Community Care, Depression, For Doctors (mostly), For Nurses and Therapists (mostly), For Researchers (mostly), In the News, International, Mental Health, NHS Digital (Previously NHS Choices), Non-Pharmacological Treatments, Quick Insights, Statistics, Systematic Reviews, UK, Universal Interest | Tagged Academy of Finland, Anti-Inflammatory Diets, Association Between Inflammation and Depression, Australia, Avoidance of Pro-Inflammatory Diets, Bazian, Beans, Behind the Headlines, Brown Rice It also contains moderate amounts of fish, Cereal Products, Cereals, CHU Clermont-Ferrand, Critical Appraisals, Deakin University, Dietary Approaches to Stop Hypertension (DASH), Dietary Behaviour, Dietary Factors, Dietary Indices, Dietary Inflammatory Index (DII), Dietary Patterns, Dietary Recommendations, Dietary Risk Factors, Epidemiology, Epidemiology and Statistics, Food and Diet, France, Fruit and Vegetables, Fruits, Gut Microbiome, Gut Microbiota, Healthy Eating, Healthy Eating Index (HEI), Human Gut Microbiome: a Potential Risk Factor for Depression, Human Gut Microbiome: a Potential Risk Factor for Mental Ill-Health, Inflammation, Inflammatory Potential of Diet, Medical Research Council, Mediterranean and DASH Diets, Mediterranean Diet, Mediterranean Diets: Bone Density, Mediterranean Diets: Frailty, Modifiable Risk Factors, Molecular Psychiatry (Journal), Nordforsk, NU-AGE Diet, NU-AGE Project, NU-AGE Trial, Nutrition, Nutrition and Depression, Nutrition and Mental Health, Nutrition and Wellbeing, Nutritional Needs, Olive Oil, Oxidative Stress, Pasta, Plant-Rich Diets, Prevention, Queen's University Belfast, Risk Factors for Depression, Science Foundation Ireland (SFI), Spain, Systematic Reviews and Meta-Analyses, Université Clermont Auvergne, University College Cork, University College London, University of Las Palmas de Gran Canaria, University of Montpellier, Wageningen University (Netherlands), White Meats, Wholegrain Bread | Leave a comment

Metabolic Syndrome and Cognitive Decline in the Elderly: a Possible Risk Factor? (PLoS One)

Posted on July 11, 2018 by Dementia and Elderly Care News

Summary The following review explores the uncertain evidence for the possible relationship(s) between Metabolic Syndrome (MetS) and increased risk of cognitive impairment in the elderly. Full Text Link Reference Assuncao, N. Sudo, FK. [and] Drummond, C. [et al] (2018). Metabolic … Continue reading →

Posted in For Doctors (mostly), For Nurses and Therapists (mostly), For Researchers (mostly), International, Quick Insights, Systematic Reviews, Universal Interest | Tagged Abdominal Obesity, Blood Triglyceride Levels, Brazil, Cardiometabolic Risk Factors, Cardiovascular Risk Factors, Components of Metabolic Syndrome, D'Or Institute for Research and Education (Rio de Janeiro), Dementia Risk Factors, Department of Psychiatry and Forensic Medicine: Federal University of Rio de Janeiro, Department of Psychology: Pontifical Catholic University of Rio de Janeiro, Department of Speech and Hearing Pathology: Federal University of Rio de Janeiro, Diseases and Medical Conditions Associated With Increased Dementia Risk: High Blood Pressure, Epidemiological Links Between T2DM Obesity Hyperinsulinemia and Metabolic Syndrome With Alzheimer's Disease, Epidemiology, Federal University of Rio de Janeiro, High Blood Pressure, High Blood Sugar, High Density Lipoproteins (HDL), High Serum Triglycerides, Hyperglycemia, Hypertension, Impaired Glucose Tolerance (IGT), Inflammation, Institute of Biomedical Sciences-Morphological Sciences Program, Institute of Medical Biochemistry Leopoldo de Meis: Federal University of Rio de Janeiro, Institute of Psychiatry: Federal University of Rio de Janeiro, Low High-Density Lipoprotein (HDL) Cholesterol Levels, Memory Clinic: D'Or Institute for Research and Education, Metabolic Syndrome, Metabolic Syndrome (MetS), Metabolic Syndrome and Cognitive Decline in the Elderly, Metabolic Syndrome: Cognitive Decline and Risk of Dementia, MetS Components and Cognitive Impairment, Midlife and Late-Life Hypertension, Non-Diabetic Hyperglycaemia (Pre-Diabetes), Nutritional and Metabolic Disorders, Obesity, Obesity - Burden of Ill-Health Links, Obesity and Risk of Neurodegeneration, Obesity Risk Factor, Overlapping Risk Factors, PLoS One, Pontifical Catholic University of Rio de Janeiro, Pre-Diabetes, Prediabetes, Risk Factors, Systematic Reviews, Systemic Inflammation and Neurodegeneration, T2DM-Related Conditions, Triglycerides Levels, Type 2 Diabetes Mellitus (T2DM) | Leave a comment

Preventative Treatment to Reduce Risk of Alzheimer’s Disease, Using Non-Steroidal Anti-Inflammatory Drugs? (NHS Choices / Journal of Alzheimer’s Disease)

Posted on March 31, 2018 by Dementia and Elderly Care News

Summary A recent article suggests that use of nonsteroidal anti-inflammatory drugs (NSAIDs) might help to reduce the risk of developing Alzheimer’s Disease, if prescription were to be commenced years before clinical signs were to develop. An NHS Choices Behind the … Continue reading →

Posted in For Doctors (mostly), For Nurses and Therapists (mostly), For Researchers (mostly), In the News, International, NHS Digital (Previously NHS Choices), Pharmacological Treatments, Quick Insights, Universal Interest | Tagged Aβ42, Alzheimer Disease Anti-Inflammatory Prevention, Alzheimer’s Disease Biomarkers, Amyloid Beta (Aβ42), Amyloid Beta Protein, Amyloid Cascade Inflammatory Hypothesis, Amyloid-β (Aβ), Amyloidogenic and Inflammatory Pathways, Aurin Biotech, Aurin Biotech Inc. Ltd. (Vancouver), ß-amyloid, Bazian, Behind the Headlines, Biomarkers, Canada, Critical Appraisals, Dementia Risk Reduction and Prevention, Dementia Saliva Testing (Pilot Study), Diagnosis of Alzheimer's Disease Based on Salivary Amyloid-β Protein 42 Levels, ELISA Method to Determine Aβ42 Levels in Saliva, Fluid Biomarker Analysis, Ibuprofen, Ibuprofen and the Reduced Risk of Alzheimer’s Disease Link, Inflammation, Journal of Alzheimer's Disease, Long-Term Ibuprofen Use, Neurodegenerative Disease Research, Neurodegenerative Diseases, Neurodegenerative Disorders, Neurodegenerative Research, Neuroinflammation, Non-Invasive Biomarkers, Non-Steroidal Anti-Inflammatory Drugs (NSAIDS), NSAIDS: Non-Steroidal Anti-Inflammatory Drugs, Preclinical Biomarkers in Alzheimer's Disease, Preventative Interventions, Prevention, Saliva Tests, Salivary Amyloid-β Protein 42 Levels, Salivary Biomarkers | Leave a comment

Animal Study Explores the Potential of a Novel Diabetes Drug for Reducing Memory Loss in Dementia – In Mice (NHS Choices / Brain Research)

Posted on January 13, 2018 by Dementia and Elderly Care News

Summary Early animal research indicates that a new drug designed for the future treatment of diabetes may (one day) have an alternative re-use for reducing the memory-loss symptoms of Alzheimer’s Disease. Mice given a modified version of a so-called triple … Continue reading →

Posted in Alzheimer's Society, Animal Studies, Charitable Bodies, For Researchers (mostly), In the News, International, NHS Digital (Previously NHS Choices), Pharmacological Treatments, Quick Insights, Universal Interest | Tagged Alzheimer's Society, Alzheimer’s Disease and Diabetes, Amyloid Plaque Load, APP/PS1 Transgenic Mouse Model, Bazian, BDNF Levels in Hippocampus of APP/PS1 Mice, BDNF: Brain-Derived Neurotrophic Factor, Behind the Headlines, Biomedical and Life Science: Lancaster University, Brain Research, Brain Research (Journal), Brain-Derived Neurotrophic Factor (BDNF), China, Critical Appraisals, Department of Human Anatomy: Shaoyang University, Diabetes Drugs, Faculty of Health and Medicine: Lancaster University, GIP Receptor Agonists, GLP-1/GIP Dual Agonists, Glucagon-Like Peptide-1 (GLP-1) Analogs, Incretin Hormones, Incretin Mimetics, Inflammation, β-Amyloid Plaques, Key Laboratory of Cellular Physiology: Shanxi Medical University, Lancaster University, Medical College: Shaoyang University, Memory Loss, Ministry of Human Resources and Social Security (Shanxi Scholarship Council of China), Morris Water Maze Test, Mouse Model of Alzheimer’s Disease, Mouse Models of Alzheimer's Disease, Neuroprotection, Neuroprotection Research, Neuroprotective Agents, Neuroprotective Effects of Triple GLP-1/GIP/Glucagon Receptor Agonist, Novel GLP-1/GIP/Gcg Receptor Agonist, Off-Label Drug Repurposing Trials, Oxidative Stress, People's Republic of China, Potential Repurposing of Drugs to Slow Progression of Alzheimer’s Disease, Repurposing GLP-1 Agonists, Repurposing of Drugs, Second Hospital Neurology Department: Shanxi Medical University, Shanxi Medical University, Shanxi Medical University (China), Shanxi Scholarship Council of China, Shaoyang University, Shaoyang University (China), Synaptophysin (SYN) Levels, Transgenic Mice, Triple GLP-1/GIP/Glucagon Receptor Agonist, Triple GLP-1/GIP/Glucagon Receptor Agonists, Triple Receptor Agonist (TA) Drugs, Type 2 Diabetes, Type 2 Diabetes Drugs Development and Re-Purposing, Type 2 Diabetes Mellitus (T2DM), Water Maze Test | Leave a comment

Septicaemia Associated with Increased Dementia Risk (Oncotarget)

Posted on November 27, 2017 by Dementia and Elderly Care News

Summary There appears to be a statistically significant association between septicemia and a subsequent increased risk of developing dementia (of the non-Alzheimer’s Disease varieties). Full Text Link Reference Chou, CH. Lee, JT. [and] Lin, CC. [et al] (2017). Septicemia is … Continue reading →

Posted in Statistics, Universal Interest | Tagged Acute Sepsis, Blood Infections, China, China Medical University (Taiwan), China Medical University Hospital (Taiwan), China Medical University: China Medical University (Taiwan), Cognitive Impairment, Dementia Risk Factors, Dementia Risk Reduction, Department of Internal Medicine: China Medical University (Taiwan), Department of Neurology: Tri-Service General Hospital (Taiwan), Department of Nuclear Medicine China Medical University (Taiwan) China Medical University (Taiwan), Diseases and Medical Conditions Associated With Dementia Risk, Division of Kidney Disease: China Medical University (Taiwan), Epidemiology, Epidemiology and Statistics, Evidence for Risk Factors of Dementia, Graduate Institute of Clinical Medical Science: China Medical University (Taiwan), Graduate Institute of Medical Sciences: National Defense Medical Center (Taiwan), Infection Induced Immune Activation, Inflammation, Inflammatory Response, Institute of Population Health Sciences: National Health Research Institutes, LHID: Longitudinal Health Insurance Database (Taiwan), Longitudinal Health Insurance Database (LHID), Management Office for Health Data: China Medical University Hospital, National Defense Medical Center (Taiwan), National Health Research Institutes (Taiwan), Overlapping Risk Factors, People's Republic of China, Risk Factors, Sepsis, Septicaemia, Septicemia, Systemic Infection and Cognitive Impairment, Taiwan, Tri-Service General Hospital: National Defense Medical Center (Taiwan) | Leave a comment

Mid-Life Blood Test for Inflammation May Predict Later-Life Dementia Risk? (NHS Choices / Neurology)

Posted on November 5, 2017 by Dementia and Elderly Care News

Summary Higher inflammatory marker scores in middle age, based on five blood-based markers of inflammation (fibrinogen, albumin, von Willebrand factor, factor VIII and white blood cell count) appear to be associated with reduced brain volume (thought to be neurodegenerative “shrinkage”) … Continue reading →

Posted in For Doctors (mostly), For Nurses and Therapists (mostly), For Researchers (mostly), In the News, International, NHS Digital (Previously NHS Choices), Quick Insights, Universal Interest | Tagged AD Signature Region Volume (Shrinkage), Albumin, ARIC Study: Atherosclerosis Risk in Communities, Atherosclerosis Risk in Communities (ARIC) Study, Baylor College of Medicine, Bazian, Behind the Headlines, Biomarker Development, Biomarkers, Biomarkers for Inflammation, Biomarkers Research Programmes, Blood-Based Biomarkers, Blood-Based Biomarkers of Pre-Symptomatic Alzheimer’s Disease, Brain Shrinkage, Brain Volume, Center for Cardiovascular Disease Prevention: Houston Methodist DeBakey Heart and Vascular Center, Critical Appraisals, Department of Medicine: University of Mississippi Medical Center, Departments of Neurology and Epidemiology: Johns Hopkins University School of Medicine, Departments of Neurology and Radiology: Mayo Clinic (Rochester), Division of Epidemiology and Community Health: University of Minnesota, Factor VIII, Fibrinogen, Hippocampal Volume, Hippocampal Volume (Memory Related), Hippocampus (Shrinkage in Late Adulthood), Houston Methodist DeBakey Heart and Vascular Center (Texas), Immune System, Immune System and Neurodegenerative Diseases, Inflammation, Inflammation and Neurodegenerative Diseases, Inflammatory Response, Johns Hopkins University School of Medicine, Mayo Clinic, Mayo Clinic: Rochester, Neurodegenerative Disease Research, Neurodegenerative Diseases, Neurodegenerative Disorders, Neurology (Journal), Occipital Lobe Volume (Shrinkage), Plasma Biomarkers, Preclinical Biomarkers and Dementia, Preclinical Biomarkers in Alzheimer's Disease, School of Public Health: University of Minnesota, Section of Cardiology: Baylor College of Medicine, Section of Cardiology: Baylor College of Medicine. Baylor College of Medicine, Systemic Inflammation, Systemic Inflammation and Neurodegeneration, United States, University of Minnesota, University of Mississippi Medical Center, University of Mississippi Medical Centre, US National Heart Lung and Blood Institute, USA, von Willebrand Factor, White Blood Cell Count | Leave a comment

More On the Association Between Periodontitis and the Risk of Developing Alzheimer’s Disease (NHS Choices / Alzheimer’s Research and Therapy)

Posted on August 25, 2017 by Dementia and Elderly Care News

Summary Analysis of data from the National Health Insurance Research Database (NHIRD) of Taiwan indicates that patients with chronic gum disease (periodontitis) are at higher risk of developing Alzheimer’s Disease. “These findings highlight the need to prevent progression of periodontal disease… … Continue reading →

Posted in For Carers (mostly), For Doctors (mostly), For Nurses and Therapists (mostly), For Researchers (mostly), In the News, International, NHS Digital (Previously NHS Choices), Parkinson's Disease, Quick Insights, Universal Interest | Tagged Alzheimer's Disease and Chronic Periodontitis, Alzheimer's Research and Therapy, Behind the Headlines, Chronic Periodontitis, Chung Shan Medical University (Taiwan), Chung Shan Medical University Hospital (Taiwan), Dementia Risk Factors, Dental and Oral Health, Dental Health, Dental Healthcare, Dental Hygiene, Dental Status, Department of Dentistry: Chung Shan Medical University Hospital, Department of Physical Medicine and Rehabilitation: Tri-Service General Hospital (Taiwan), Epidemiology, Epidemiology and Statistics, Gum Disease (Periodontitis), Inflammation, Inflammation and Neurodegenerative Diseases, Inflammatory Response, Lifestyle Risk Factors, Modifiable Risk Factors, National Defense Medical Center (Taiwan), National Health Insurance Research Database (NHIRD) of Taiwan, Oral Health, Oral Health and Cognitive Function, Oral Healthcare, Oral Hygiene, Parkinson's Disease and Chronic Periodontitis, PeerJ, Periodontal Inflammatory Disease, Periodontitis, Periodontitis and Risk of Developing Alzheimer’s Disease, Risk Factors, Risk Factors and Preventive Interventions for Alzheimer Disease, Risk Factors for Alzheimer's Diseease, Risk Factors for Parkinson's Disease, School of Dentistry: Chung Shan Medical University, School of Medicine: National Defense Medical Center, Section of Dentistry: Zuoying Branch of Kaohsiung Armed Forces General Hospital, Taiwan, Zuoying Branch of Kaohsiung Armed Forces General Hospital (Taiwan) | Leave a comment

Early Research on Stress and Social Disadvantage as Potential Risk Factors (BBC News / AAIC)

Posted on July 20, 2017 by Dementia and Elderly Care News

Summary Early research findings presented at the Alzheimer’s Association International Conference in London suggest that stressful life events, and more generally the chronic stress of enduring social deprivation life-long, may age the brain. The researchers claim that extremely stressful experiences … Continue reading →

Posted in BBC News, Charitable Bodies, Community Care, For Nurses and Therapists (mostly), For Researchers (mostly), For Social Workers (mostly), In the News, International, Quick Insights, UK, Universal Interest | Tagged 2017 Alzheimer’s Association International Conference (AAIC®2017), African Americans, Alzheimer’s Association AAIC Press Office, Alzheimer’s Association International Conference (AAIC®2017), Centre for the Study of Social Cohesion: University of Oxford, Cortisol, Dementia Risk Factors, Dementia Risk Prevention, Dementia Risk Reduction, Dementia Risk Reduction and Prevention, Environmental Risk Factors, Epidemiology, Epidemiology and Statistics, Ethnicity, Health Determinants, Health Improvement, Health Inequalities, Health Policy, Immune System, Immune System and Neurodegenerative Diseases, Improving Local Public Health, Improving Public Health, Inflammation, Inflammation and Neurodegenerative Diseases, Inflammatory Response, Lifestyle Risk Factors, Modifiable Risk Factors, Necroptosis, Neurodegenerative Disease Research, Neurodegenerative Diseases, Neurodegenerative Disorders, Neuroinflammation, Overlapping Risk Factors, Potentially Modifiable Socio-Environmental Risk Factors, Prevention, Prevention Agenda, Prevention of Dementia, Reducing Health Inequalities, Risk Factors, Social Epidemiology, Socio-Environmental Risk Factors, Stressful Life Experiences, University of Wisconsin School of Medicine, University of Wisconsin-Milwaukee | Leave a comment

Tag Archives: Inflammation

More on the Possible Role of Neuroinflammation in Frontotemporal Dementia (Bazian / Brain)

Dementia Research Centre in Wales (BBC News)

Mediterranean Diets: Good for Mental Health? (BBC News / Molecular Psychiatry / NHS Choices)

Preventative Treatment to Reduce Risk of Alzheimer’s Disease, Using Non-Steroidal Anti-Inflammatory Drugs? (NHS Choices / Journal of Alzheimer’s Disease)

Septicaemia Associated with Increased Dementia Risk (Oncotarget)

More On the Association Between Periodontitis and the Risk of Developing Alzheimer’s Disease (NHS Choices / Alzheimer’s Research and Therapy)

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