Tag Archives: Johns Hopkins University School of Medicine

Mid-Life Blood Test for Inflammation May Predict Later-Life Dementia Risk? (NHS Choices / Neurology)

Summary Higher inflammatory marker scores in middle age, based on five blood-based markers of inflammation (fibrinogen, albumin, von Willebrand factor, factor VIII and white blood cell count) appear to be associated with reduced brain volume (thought to be neurodegenerative “shrinkage”) … Continue reading

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Further Research Backs Speculation Linking the Immune System and Parkinson’s Disease (BBC News / Nature)

Summary Further evidence has emerged suggesting that malfunctioning in the body’s immune system may contribute to the development and progression of Parkinson’s Disease. T-cells appear to attack alpha-synuclein – a protein which accumulates in Parkinson’s Disease – after confusing this … Continue reading

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Update on Overuse: Further Information on the Potential Costs and Risks of Over-Diagnosis and Over-Treatment (JAMA Internal Medicine)

Summary An updated systematic review indicates a growing awareness and debate concerning overuse of medical care. The literature on a broadly Too Much Medicine and / or a Less is More theme has grown rapidly, whereby reviewers found 821 relevant … Continue reading

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Recent Reviews on the Association Between Type 2 Diabetes Mellitus and Dementia (Clinical Interventions in Aging / WJD)

Summary There is growing awareness of the relationships between Type 2 Diabetes mellitus, Alzheimer’s Disease and other forms of dementia. Full Text Link Reference Li, X. Song, D. [and] Leng, SX. (2015). Link between type 2 diabetes and Alzheimer’s Disease: … Continue reading

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Infographic on Hearing Loss and Dementia (MD Hearing Aid / Digital Third Coast / JAMA / Neuropsychology / Archives of Neurology)

Summary Hearing loss is thought to be a contributing factor to dementia. Hearing loss has some symptoms in common with dementia and can be misdiagnosed. The following resource from the United States presents a simplified (“infographic”) examination of the possible … Continue reading

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Recent Systematic Reviews and Meta-Analyses on Delirium

Access to the full-text of these articles may require a suitable Athens password, a journal subscription or payment. Gore, RL. Vardy, ER. O’Brien, JT. (2014). Delirium and dementia with Lewy bodies: distinct diagnoses or part of the same spectrum? Journal of … Continue reading

Posted in Acute Hospitals, Delirium, Diagnosis, For Doctors (mostly), For Nurses and Therapists (mostly), For Researchers (mostly), International, Mental Health, Systematic Reviews | Tagged , , , , , , , , , , , , , , | Leave a comment

Little Evidence of Saturated Fats Increasing Risks of Coronary Disease; or of Presumed Cardioprotective Effect of Polyunsaturated Fats (BBC News / NHS Choices / Annals of Internal Medicine)

Summary A recent systematic review of data from 72 studies, involving more than 600,000 participants, indicates that – contrary to earlier official guidance – there is little evidence that changing the type of fat consumed from “bad” saturated fat to “healthier” … Continue reading

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