Tag Archives: Journal of Alzheimer’s Disease

Transcranial Electromagnetic Treatment in Alzheimer’s Disease: Early Promising Results? (JAD / Bazian)

Posted on September 25, 2019 by Dementia and Elderly Care News

Summary Transcranial Electromagnetic Treatment (TEMT) for persons with mild / moderate Alzheimer’s Disease, delivered ia a bathing cap-style head device called the MemorEM, appears to bring about various statistically significant improvements without any observable adverse effects. Benefits are said to include: “ …cognitive enhancement, changes to CSF / … Continue reading →

Posted in For Doctors (mostly), For Nurses and Therapists (mostly), For Researchers (mostly), In the News, International, Management of Condition, Models of Dementia Care, NHS Digital (Previously NHS Choices), Non-Pharmacological Treatments, Quick Insights, Universal Interest | Tagged 2DG-PET, ADAS-Cog: Alzheimer’s Disease Assessment Scale - Cognitive Subscale, Adverse Event Assessment, Aβ Accumulation, Aβ-Plaques, Alzheimer's Disease Assessment Scale Cognitive Subscale (ADAS-Cog), Alzheimer’s Disease Biomarkers, Alzheimer’s Disease Cooperative Study - Activities of Daily Living, Angel Investor Forum, Bazian, Behind the Headlines, Blood Proteins as Biomarkers of Disease Research, Blood-Based Biomarkers, Byrd Alzheimer's Institute (Tampa Florida), Cerebral Metabolic Rate for Glucose (Via 2DG-PET), Cerebrospinal Fluid (CSF), Cerebrospinal Fluid (CSF) Biomarkers, Clock Drawing Test, College of Pharmacy: University of South Florida, Critical Appraisals, CSF Biomarkers, Czech Republic, Department of Neurology: Charles University (Prague), Diffusion Tensor Imaging (DTI), Digit Span, FDG-PET Imaging, fMRI, Functional Magnetic Resonance Imaging (fMRI), Glass Charitable Foundation, Invicro (Boston USA), Journal of Alzheimer's Disease, Journal of Alzheimer’s Disease (JAD), Left Coast Engineering (Escondido California), MemorEM (Transcranial Electromagnetic Stimulation), Motol University Hospital (Prague), MRI Scans, National Institute of Neurological Disorders and Stroke (NINDS), NeuroEM Therapeutics Inc. (Phoenix Arizona), Ocotillo Electromagnetics Inc. (Chandler Arizona), olumbia Suicide Severity Rating Scale, Plasma Biomarkers, Rey Auditory Verbal Learning Test (Rey AVLT), Rey AVLT, RF Exposure Laboratory (San Marcos California), School of Aging Studies: University of South Florida, Transcranial Brain Stimulation, Transcranial Electromagnetic Treatment (TEMT), United States, University Diagnostic Institute (Tampa Florida), University of South Florida, University of South Florida Health / Byrd Alzheimer's Institute, USA | Leave a comment

Unexpected Results From the Dementia and Physical Activity (DAPA) Trial? (Pharmacoeconomics Open / JAD)

Posted on June 15, 2019 by Dementia and Elderly Care News

Summary Previous research has suggested that physical exercise has the potential to slow the progression of dementia in people with pre-existing mild cognitive impairment through to moderate dementia. Evidence for the cost-effectiveness of structured physical activity programmes has been lacking, … Continue reading →

Preventative Treatment to Reduce Risk of Alzheimer’s Disease, Using Non-Steroidal Anti-Inflammatory Drugs? (NHS Choices / Journal of Alzheimer’s Disease)

Posted on March 31, 2018 by Dementia and Elderly Care News

Summary A recent article suggests that use of nonsteroidal anti-inflammatory drugs (NSAIDs) might help to reduce the risk of developing Alzheimer’s Disease, if prescription were to be commenced years before clinical signs were to develop. An NHS Choices Behind the … Continue reading →

Posted in For Doctors (mostly), For Nurses and Therapists (mostly), For Researchers (mostly), In the News, International, NHS Digital (Previously NHS Choices), Pharmacological Treatments, Quick Insights, Universal Interest | Tagged Aβ42, Alzheimer Disease Anti-Inflammatory Prevention, Alzheimer’s Disease Biomarkers, Amyloid Beta (Aβ42), Amyloid Beta Protein, Amyloid Cascade Inflammatory Hypothesis, Amyloid-β (Aβ), Amyloidogenic and Inflammatory Pathways, Aurin Biotech, Aurin Biotech Inc. Ltd. (Vancouver), ß-amyloid, Bazian, Behind the Headlines, Biomarkers, Canada, Critical Appraisals, Dementia Risk Reduction and Prevention, Dementia Saliva Testing (Pilot Study), Diagnosis of Alzheimer's Disease Based on Salivary Amyloid-β Protein 42 Levels, ELISA Method to Determine Aβ42 Levels in Saliva, Fluid Biomarker Analysis, Ibuprofen, Ibuprofen and the Reduced Risk of Alzheimer’s Disease Link, Inflammation, Journal of Alzheimer's Disease, Long-Term Ibuprofen Use, Neurodegenerative Disease Research, Neurodegenerative Diseases, Neurodegenerative Disorders, Neurodegenerative Research, Neuroinflammation, Non-Invasive Biomarkers, Non-Steroidal Anti-Inflammatory Drugs (NSAIDS), NSAIDS: Non-Steroidal Anti-Inflammatory Drugs, Preclinical Biomarkers in Alzheimer's Disease, Preventative Interventions, Prevention, Saliva Tests, Salivary Amyloid-β Protein 42 Levels, Salivary Biomarkers | Leave a comment

Earlier Diagnosis of Alzheimer’s Disease Using Saliva Test? (NHS Choices / JAD)

Posted on May 25, 2017 by Dementia and Elderly Care News

Summary Pilot research indicates that a chemical in the saliva can be used to differentiate, with relatively high accuracy, between persons who are currently healthy, those with mild cognitive impairment (MCI), and others with Alzheimer’s Disease. Potentially, salivary biomarkers could … Continue reading →

Posted in Diagnosis, For Doctors (mostly), For Nurses and Therapists (mostly), For Researchers (mostly), In the News, International, NHS Digital (Previously NHS Choices), Quick Insights, Universal Interest | Tagged 1H NMR-Based Metabolomics, Alzheimer’s Disease Biomarkers, Alzheimer’s Early Screening, Beaumont Health, Beaumont Research Institute: Beaumont Health, Behind the Headlines, Biomarker Development, Biomarkers, Biomarkers Predicting Cognitive Decline and Alzheimer's Disease, Canada, Dementia Saliva Testing (Pilot Study), Dementia Screening, Departments of Biological and Computing Sciences: University of Alberta, Early Diagnosis, Early Diagnosis of Alzheimer's Disease, Early Diagnosis of Alzheimer’s Disease Using Saliva, Fred A. and Barbara M. Erb Family Foundation, JAD, Journal of Alzheimer's Disease, MCI: Mild Cognitive Impairment, Metabolomics, Mild Cognitive Impairment (MCI), NHS Digital (Previously NHS Choices), Non-Invasive Biomarkers, Nuclear Magnetic Resonance Spectroscopy (NMR), Oakland University, Potential for Metabolomics and Saliva in Early Diagnosis of Alzheimer’s Disease, Preclinical Biomarkers and Dementia, Preclinical Biomarkers in Alzheimer's Disease, Saliva, Saliva Tests, Salivary Biomarkers, Screening, Screening for Dementia, Screening Tests, Surrogate Biomarkers of Neurodegeneration, United States, University of Alberta, USA, William Beaumont School of Medicine: Oakland University | Leave a comment

On the Benefits of Supportive Social Networks (Journal of Alzheimers Disease / JGCR)

Posted on May 16, 2017 by Dementia and Elderly Care News

Summary Data from the English Longitudinal Study of Ageing (ELSA) has been used to demonstrate that positive social support from friends, family etc. is associated statistically with a reduced risk of developing dementia. Conversely, negative social support appears to increase … Continue reading →

Posted in Community Care, For Carers (mostly), For Nurses and Therapists (mostly), For Researchers (mostly), Mental Health, Quick Insights, Statistics, UK, Universal Interest | Tagged Activities of Daily Living (ADL) Scale, Activities of Daily Living (ADLs), ADL Among Hospitalised Elderly Patients, Benefits of Supportive Social Networks, Centre for Primary Health and Social Care: London Metropolitan University, Dementia Risk Factors, Department of Applied Health Research: University College London, Department of Epidemiology and Public Health (University College London), Emotional and Social Isolation, English Longitudinal Study of Ageing (ELSA), Epidemiology, Epidemiology and Statistics, Feelings Relating to Social Relationships, Functional Dependence and Perceived Social Support, India, Indirect Pathways by Which Social Connections Influence Disease Morbidity and Mortality, Influence of Social Connections on Disease Morbidity and Mortality, Institute of Mental Health: University of Nottingham, Involvement in Social Relationships, Journal of Alzheimer's Disease, Journal of Geriatric Care and Research (JGCR), Lifestyle Risk Factors, London, London Metropolitan University, Loneliness and Social Isolation, Modifiable Risk Factors, Multi-Dimensional Scale of Perceived Social Support (MSPSS), National Institute of Nursing Education (NINE); Chandigarh (India), Negative Social Support, Norwich, Norwich Medical School: University of East Anglia, Nottingham, Perceived Social Support of Hospitalised Elderly Patients, Personalised Social Interaction, Positive Social Support, Post-Graduate Institute of Medical Education and Research (PGIMER); Chandigarh (India), Potentially Modifiable Socio-Environmental Risk Factors for Dementia, Professor Martin Orrell, Promoting Independence in Dementia (PRIDE) Programme, Psychosocial and Lifestyle-Related Risk Factors, Psychosocial Protective and Risk Factors, Satisfaction with Social Relationships and / or Participation, Social Connectedness, Social Epidemiology, Social Interaction, Social Isolation, Social Isolation: Social Economic and Environmental Determinant (SEED) of Health, Social Networks, Social Relationships, Social Support, Socio-Environmental Risk Factors for Dementia, Structural and / or Functional Aspects of Social Relationships, Supportive Social Networks, Supportive Social Relationships, University College London, University of East Anglia, University of Nottingham | Leave a comment

People With Dementia Living Alone in the Community (Journal of Alzheimer’s Disease)

Posted on February 18, 2017 by Dementia and Elderly Care News

Summary Research, based on experiences and outcomes concerning people with dementia living alone (with and without help from an informal caregiver) in Germany, indicates that it is possible – provided adequate support services are available – to survive without significant … Continue reading →

Posted in Commissioning, Community Care, Depression, Falls Prevention, For Nurses and Therapists (mostly), For Researchers (mostly), For Social Workers (mostly), Integrated Care, International, Management of Condition, Models of Dementia Care, Non-Pharmacological Treatments, Person-Centred Care, Quick Insights, Statistics, Universal Interest | Tagged Bayer Activities of Daily Living Scale (B-ADL), Challenges of Living with Dementia, Community-Based Care, Community-Based Interventions, Community-Based Services, Community-Based Support, Community-Dwelling Older Adults, Community-Dwelling Older People with Dementia, Control and Independence, Culture Change in Health and Care, Dementia Care Management (DCM), DemTect, Department of Psychiatry and Psychotherapy: University Medicine Greifswald, Dignified Independent Living With Care, Evaluating Integrated and Community-Based Care, German Center for Neurodegenerative Diseases (DZNE), Germany, Health and Care of Older People, Help With Medication, Home Care, Home Support for People Living With Dementia, Home-Delivered Meals, Housekeeping Assistance, Improving Outcomes for People Living With Dementia, Improving the Quality of Life for People With Dementia, Independence, Independence and Wellbeing, Independence at Home, Independence in Older Adults, Independent Living, Informal Care, Informal Caregiving, Informal Carers, Institute for Community Medicine: University Medicine Greifswald, Integrated and Community-Based Care, Integration of Health and Care, International Comparisons, Journal of Alzheimer's Disease, Living Independently At Home, Living Well with Dementia, Living Well With Dementia: German Statistics, Living with Dementia, Living With Neurological Conditions, Maintaining Independence, Measures of Living Arrangements and Informal Care, People With Dementia Living Alone, Quality of Life-AD (QoL-AD), Screening For Dementia in GP Practices, Staying Independent, Support For Living Independently At Home, Sustainable Health and Care Services, Transforming Participation in Health and Care, University Medicine Greifswald, Unmet Needs of Community-Dwelling Primary Care Patients With Dementia in Germany, Utilization of Health and Nursing Care Services, What Works Resource Pack: Involving People Living with Dementia | Leave a comment

Altered Humour Predicts Behavioural Variant Frontotemporal Dementia? (BBC News / MRC / JAD / Cortex)

Posted on November 12, 2015 by Dementia and Elderly Care News

Summary Researchers at University College London are interested in whether sense of humour changes might help predict frontotemporal dementia (FTD). Their latest paper suggests that changes in sense of humour can be an early sign of this type of dementia, … Continue reading →

Posted in BBC News, Diagnosis, For Doctors (mostly), For Nurses and Therapists (mostly), For Researchers (mostly), In the News, Quick Insights, UK, Universal Interest | Tagged Altered Humour, Altered Sense of Humour, Alzheimer's Research UK, BBC Health News, Behavioural Frontotemporal Dementia (bvFTD), Behavioural Variant Frontotemporal Dementia (bvFTD), BV-FTD, Canadian Institutes of Health Research, Changes in Humour, Cortex (Journal), Dementia Research Centre: University College London, Dementia Research Centre: University College London: UCL Institute of Neurology: University College London, Frankly Inappropriate Humour Responses, Fronto-Temporal Dementia (FTD), Frontotemporal Dementia (FTD), Frontotemporal Lobar Degeneration, Frontotemporal Lobar Degeneration (FTLD), FTLD: Frontotemporal Lobar Degeneration, Humour in Dementia, Humour Processing in Frontotemporal Lobar Degeneration, JAD, Journal of Alzheimer's Disease, Medical Research Council (MRC), MRC, Neurodegeneration, Neurodegenerative Disease Research, Neurodegenerative Diseases, Neurodegenerative Disorders, Neurodegenerative Research, Neurology, NIHR Queen Square Dementia Biomedical Research Unit, Semantic Dementia, UCL Institute of Neurology: University College London, University College London, Wellcome Trust | Leave a comment

Systematic Review of Blood Biomarkers for Alzheimer’s Disease Onset and Progression (Journal of Alzheimer’s Disease)

Posted on April 7, 2014 by Dementia and Elderly Care News

Summary Blood-based protein biomarkers to predict the onset and progression of Alzheimer’s Disease (AD) would assist in timely diagnosis and would also be beneficial for clinical trials in helping with the selection of subjects for preventative trials. This systematic review … Continue reading →

Posted in Diagnosis, For Doctors (mostly), For Researchers (mostly), International, Systematic Reviews, UK | Tagged AddNeuroMed (ANM), Alzheimer's Research UK, Apolipoprotein E, Aristotle University, Biological Networks Gene Ontology tool (BINGO), Biomarker Assessments in Alzheimer’s Disease Clinical Trials, Biomarkers, Biomarkers Predicting Cognitive Decline and Alzheimer's Disease, Biomedical Research Unit for Dementia: South London and Maudsley NHS Foundation, Blood Proteins as Biomarkers of Disease Research, Blood-Based Biomarkers, Candidate Blood Proteome Markers, Complement C3, Database for Annotation, Department of Neurobiology: Karolinska Institutet-Stockholm University, France, Gene Ontology (GO), Greece, INSERM, INSERM: University of Toulouse, Institute of Psychiatry: King's College London, Italy, α-1-antitrypsin, α-2-macroglobulin, Journal of Alzheimer's Disease, Karolinska Institutet, King's Health Partners (ARUK/DCR) Research Cohorts, Kings College London, Kuopio University Hospital, Kyoto Encyclopedia of Genes and Genomes (KEGG), Maudsley BRC Dementia Case Registry, Medical University of Lodz, NIHR Biomedical Research Centre for Mental Health, Non-Invasive Biomarkers, Plasma Biomarkers, Poland, Protein-Based Biomarkers in Blood May Deliver Accurate Diagnoses, SomaLogic (Boulder Colorado), SomaLogic's SOMAscan Proteomics, South London and Maudsley NHS Foundation, Sweden, University of Eastern Finland, University of Perugia, USA, Visualization and Integrated Discovery (DAVID) | Leave a comment

Cognitive and Neuroimaging Predictors of Progression from Mild Cognitive Impairment to Dementia (NHS Choices / Journal of Alzheimer’s Disease)

Posted on December 27, 2013 by Dementia and Elderly Care News

Summary The detection of pre-clinical Alzheimer’s Disease appears to be accomplished best by the use of a combination of information, taken from targeted neuroimaging and complementary neuropsychological assessments of cognitive functioning. This combination of approaches may be necessary in order to … Continue reading →

Posted in Acute Hospitals, Community Care, Diagnosis, For Doctors (mostly), For Nurses and Therapists (mostly), For Researchers (mostly), In the News, International, NHS Digital (Previously NHS Choices), Patient Care Pathway, Quick Insights, Universal Interest | Tagged 1Institut Universitaire de Gériatrie de Montréal, Behind the Headlines, Canada, Canadian Institutes of Health Research, Canadian Institutes of Health Research (CIHR), Cortical Thickness, Cortical Thinning, Critical Appraisals, Detection of Incipient Dementia, Heart and Stroke Foundation of Canada, Hippocampal Volume, Institut Universitaire de Gériatrie de Montréal, Journal of Alzheimer's Disease, Magnetic Resonance Imaging (MRI), MCI: Mild Cognitive Impairment, Middle Frontal Gyri, Mild Cognitive Impairment, Mild Cognitive Impairment (MCI), Montréal, MRI, MRI Brain Imaging, MRI Scans, Neuroimaging, Neuropsychological Measures, Progression of Mild Cognitive Impairment to Dementia, Right Anterior Cingulate, Transition from Cognitive Impairment to Dementia, Université de Montréal, White Matter Hyperintensities | Leave a comment

Two Recent “Behind the Headlines” Critical Appraisals (NHS Choices / Evolution, Medicine and Public Health / Journal of Alzheimer’s Disease)

Posted on October 2, 2013 by Dementia and Elderly Care News

Summary The NHS Choices “Behind the Headlines” service produces regular critical appraisals of recent research into dementia-related topics which have appeared in the news. Here are two of these: The Association Between Economic Development, Sanitation, Cleanliness and the Estimated Prevalence of … Continue reading →

Posted in For Doctors (mostly), For Researchers (mostly), In the News, International, NHS Digital (Previously NHS Choices), Statistics, Universal Interest | Tagged Alzheimer’s Disease Disability Adjusted Life Year (AD DALY), Alzheimer’s Disease Disability Adjusted Life Years, Behind the Headlines, Challenged SVGp12 Cells, Chronic Oral-Pathogen-Related Virulence Factor: University of Central Lancashire, Cleanliness, Critical Appraisals, Dental Health, Dental Sciences Research Group: University of Central Lancashire, Dental Status, Economic and Social Research Council, Economic Development, Evolution Medicine and Public Health (Journal), Global Burden of Disease, Gonville & Caius College: Cambridge, Gum Bacteria (Lipopolysaccharides), Gum Disease, Hygiene Hypothesis, Immunofluorescence, Immunofluorescence Labeling, Inflammation, Journal of Alzheimer's Disease, Lipopolysaccharides, McMaster University: Canada, Oral Health, Oral Healthcare, Pathogens, Periodontal Disease Bacteria, Periodontopathic Virulence Factors, Porphyromonas gingivalis, Sanitation, School of Postgraduate Medical and Dental Education, Tannerella forsythia, Treponema denticola, University of Cambridge, University of Central Lancashire, University of Glasgow, University of Utah, World Health Organization (WHO) Global Burden of Disease Database, World Health Organization’s Global Burden of Disease | Leave a comment

Tag Archives: Journal of Alzheimer’s Disease

Transcranial Electromagnetic Treatment in Alzheimer’s Disease: Early Promising Results? (JAD / Bazian)

Preventative Treatment to Reduce Risk of Alzheimer’s Disease, Using Non-Steroidal Anti-Inflammatory Drugs? (NHS Choices / Journal of Alzheimer’s Disease)

Earlier Diagnosis of Alzheimer’s Disease Using Saliva Test? (NHS Choices / JAD)

Altered Humour Predicts Behavioural Variant Frontotemporal Dementia? (BBC News / MRC / JAD / Cortex)

Systematic Review of Blood Biomarkers for Alzheimer’s Disease Onset and Progression (Journal of Alzheimer’s Disease)

Cognitive and Neuroimaging Predictors of Progression from Mild Cognitive Impairment to Dementia (NHS Choices / Journal of Alzheimer’s Disease)

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