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- Dementia-Friendly Communities Provision, Viewed as a Social Determinant of Health (JGCR / NHS England / WHO)
- International Perspectives on the Possible Impact of the COVID-19 Pandemic and Lockdown on Abuse of the Elderly (JGCR / American Journal of Geriatric Psychiatry / JAGS)
- Updates Relating to the Lancet Commission on Dementia Prevention, Intervention, and Care (Lancet / Alzheimer’s Research and Therapy / Alzheimer’s and Dementia)
- A Brief Review of How the COVID-19 Pandemic Relates to Elderly Care and Research (JGCR)
- Some Speculated / Potential Benefits of COVID-19 (JGCR / BBC Radio 4’s Rethink / BGS)
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Tag Archives: Karolinska Institute
Hormone Replacement Therapy Associated With Small Increased Risk of Developing Alzheimer’s Disease (BBC News / BMJ / NHS Digital)
Summary Research from Finland discovered a 9% to 17% increase in the risk of developing Alzheimer’s Disease in women taking hormone replacement therapy (HRT) for more than 10 years. The public has been advised not to be overly concerned, as absolute risk … Continue reading
Posted in BBC News, For Doctors (mostly), For Nurses and Therapists (mostly), For Researchers (mostly), In the News, International, NHS Digital (Previously NHS Choices), Pharmacological Treatments, Quick Insights, Statistics, Universal Interest
Tagged BBC Health News, Behind the Headlines, BMJ, BMJ Publishing Group Ltd, British Medical Journal (BMJ), Dementia Risk Factors, Dementia Risk Reduction and Prevention, Division of Family Medicine: Karolinska Institute, EPID Research Oy (Finland), Epidemiology, Epidemiology and Statistics, Estradiol, Finland, Folkhälsan Research Center (Finland), Helsinki University Hospital, Hormone Replacement Therapy, Hormone Therapy and Cognition, HRT, Jane and Aatos Erkko Foundation, Karolinska Institute, Karolinska Institute: Department of Neurobiology Care Sciences and Society, Medroxyprogesterone Acetate, Modifiable Risk Factors, National Institute for Health and Welfare (Finland), NHS Digital, NHS Digital (Formerly NHS Choices), Norethisterone Acetate, Obstetrics and Gynecology: University of Helsinki and Helsinki University Hospital, Oestrogen-Progestogen Therapy, Postmenopausal Hormone Therapy and Risk of Alzheimer’s Disease, Progestogens, Research Centre for Child Psychiatry: University of Turku, Risk Factors, Risk Factors and Preventive Interventions for Alzheimer Disease, Sweden, University of Helsinki and Helsinki University Hospital, University of Turku
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Further Confirmation of the Benefits of Education for Cognitive Reserve? (NHS Choices / BMJ)
Summary A detailed investigation into modifiable risk factors for Alzheimer’s Disease provides further confirmation that levels of educational attainment are associated with a reduced risk of developing Alzheimer’s Disease. The following NHS Choices Behind the Headlines critical appraisal provides a … Continue reading
Posted in Community Care, For Carers (mostly), For Doctors (mostly), For Nurses and Therapists (mostly), For Researchers (mostly), In the News, International, NHS Digital (Previously NHS Choices), Non-Pharmacological Treatments, Quick Insights, Statistics, Universal Interest
Tagged Access to Education, Additional Year of Education Associated With an 11% Reduction in Risk of Alzheimer's Disease, Alzheimer’s Disease Genetics Consortium (ADGC), Bazian, Behind the Headlines, Benefits of Education, BMJ, BMJ Publishing Group Ltd, Cognitive Reserve, Cognitive Reserve Hypothesis, Cohorts for Heart and Aging Research in Genomic Epidemiology Consortium (CHARGE), CoSTREAM Consortium, Dementia Risk Factors, Department of Clinical Neurosciences: University of Cambridge, Department of Public Health and Primary Care: University of Cambridge, Educational Attainment, Epidemiology, Epidemiology and Statistics, European Alzheimer's Disease Initiative (EADI), European Union's Horizon 2020, Formal Education and Complex Work (Cognitive Reserve), Genetic and Environmental Risk in Alzheimer’s Disease Consortium (GERAD), Genetic Risk Factors, Genetic Variants, German Centre for Neurodegenerative Diseases, German Centre for Neurodegenerative Diseases (DZNE), Germany, Institute for Stroke and Dementia Research: Klinikum der Universität München, Institute of Environmental Medicine: Karolinska Institutet (Sweden), International Genomics of Alzheimer's Project (IGAP), International Genomics of Alzheimer’s Project, Karolinska Institute, Karolinska Institutet, Klinikum der Universität München, Ludwig-Maximilian University, Ludwig-Maximilians University ( Munich), Mendelian Randomisation, Modifiable Risk Factors, MRC Biostatistics Unit: University of Cambridge, Munich, Munich Cluster for Systems Neurology (SyNergy): Germany, Overlapping Risk Factors, Potentially Modifiable Socio-Environmental Risk Factors, Potentially Modifiable Socio-Environmental Risk Factors for Dementia, Risk Factors for Alzheimer's Diseease, Socio-Environmental Risk Factors, Socio-Environmental Risk Factors for Dementia, Stroke Research Group: University of Cambridge, Sweden, Sweden; Karolinska Institutet, Swedish Brain Foundation, Unit of Nutritional Epidemiology: Karolinska Institutet (Sweden), University of Cambridge
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Parkinson’s Disease Awareness Week 2017 (BBC News / Nature Biotechnology / Parkinson’s UK)
Summary Researchers hope one day to be able to replace the damaged dopamine-producing neurons at the root-cause of by Parkinson’s Disease by injecting new replacement brain cells, possibly derived from re-programmed astrocytes. Full Text Link Reference Brain cell therapy ‘promising’ … Continue reading
Posted in Animal Studies, BBC News, Charitable Bodies, In the News, International, Person-Centred Care, Quick Insights, UK, Universal Interest
Tagged Ageing Population, Astrocytes, Austria, Awareness and Campaigns, Awareness and Understanding, Awareness Campaigns, Awareness Raising, BBC Health News, Biomedical Research Institute of Malaga (IBIMA), Cell Replacement Therapy for Neurodegenerative Diseases, Center for Brain Research: Medical University of Vienna, Department of Medical Biochemistry and Biophysics: Karolinska Institutet, Department of Molecular Neurosciences: Medical University of Vienna, Department of Neuroscience: Karolinska Institutet, Department of Pharmacology: Malaga University, Dopamine, Dopamine Neuron Degeneration, Faculty of Medicine: Malaga University, Induced Dopamine Neurons (iDANs), Induced Neurons (iNs), Induced Pluripotent Stem (iPS) Cells, Karolinska Institute, Karolinska Institute in Stockholm, Karolinska Institutet, Laboratory of Molecular Neurobiology: Karolinska Institutet, Malaga University, Medical University of Vienna, Midbrain Dopamine Neurons (mDAs), Nature Biotechnology (Journal), Neurodegenerative Disease Research, Neurodegenerative Diseases, Neurodegenerative Disorders, Parkinson's Awareness Month, Parkinson's Awareness Week, Parkinson’s Awareness Week (2017), Parkinson’s Disease Awareness Week (2017), Parkinson’s UK, Parkinson’s UK (Parkinsons Disease Society), Professor David Dexter: Parkinson's UK, Spain Institute for Stem Cell Biology and Regenerative Medicine: Stanford University, Stanford University, Substantia Nigra, Sweden, United States, USA, World Parkinson’s Day
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More on Blood-Based Biomarkers of Pre-Symptomatic Alzheimer’s Disease (BBC News / Translational Psychiatry)
Summary A further possibly significant step forwards towards developing a blood test which might be able to predict the risk of Alzheimer’s Disease has been reported. Full Text Link Reference Gallagher, J. (2015). Blood chemical predicts brain decline. London: BBC … Continue reading
Posted in BBC News, Diagnosis, For Doctors (mostly), For Nurses and Therapists (mostly), For Researchers (mostly), In the News, International, Quick Insights, Universal Interest
Tagged AddNeuroMed (ANM) SOMAscan Data Set, Alzheimer’s Disease Biomarkers, APOE Genotyping, Aristotle University, BBC Health News, Biomarkers, Biomarkers Predicting Cognitive Decline and Alzheimer's Disease, Blood Proteins as Biomarkers of Disease Research, Blood-Based Biomarkers, Blood-Based Biomarkers of Pre-Symptomatic Alzheimer’s Disease, CANTAB™ Neuropsychological Tests, Conversion to Dementia From Prodromal Disease, Department of Internal Medicine and Geriatric Medicine: INSERM University of Toulouse, Department of Neurobiology Care Sciences and Society: Karolinska Instituet, Department of Neurology: Aristotle University, Department of Old Age Psychiatry and Psychotic Disorders, Department of Old Age Psychiatry: King's College London, Department of Psychiatry: Oxford University, Department of Twin Research and Genetic Epidemiology: King’s College London, Finland, France, Greece, INSERM: University of Toulouse, Institute of Clinical Medicine: University of Eastern Finland, Institute of Gerontology and Geriatrics: University of Perugia, Institute of Psychiatry Psychology and Neuroscience: King’s College London, Italy, Karolinska Instituet (Stockholm Sweden), Karolinska Institute, Kings College London, MAPKAPK5, MAPKAPK5 and MAP2K4, Medical University of Tódź, Mitogen-Activated Protein Kinase (MAPK) MAPKAPK5 Protein, Monozygotic Twins, MRC Social Genetic and Developmental Psychiatry Centre: King’s College London, NeuroCenter Kuopio University Hospital, NIHR Biomedical Research Centre for Mental Health and Biomedical Research Unit for Dementia: South London and Maudsley NHS Foundation, Non-Invasive Biomarkers, Oxford University, Plasma Biomarkers, Plasma Protein Markers of MRI Measures in Asymptomatic Individuals, Poland, Preclinical Biomarkers in Alzheimer's Disease, Protein MAPKAPK5, Protein-Based Biomarkers in Blood May Deliver Accurate Diagnoses, Proteomic Analysis, Proteomics, SomaLogic (USA), SomaLogic's SOMAscan Proteomics, Translational Psychiatry, TwinsUK, University of Perugia, USA, Warneford Hospital: Oxford
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Northern Countries: Environmental Risk Factors Behind Geographical Variations in Dementia Risk? (BBC News / Epidemiology)
Summary People living further north appear to be more likely to develop dementia. Scientists mapped prevalence of dementia in Scotland among 37,000 people born in 1921. A second study involved over 26,000 Swedish twins living in different parts of that … Continue reading
Posted in BBC News, For Doctors (mostly), For Nurses and Therapists (mostly), For Researchers (mostly), In the News, International, Quick Insights, Scotland, Statistics, UK, Universal Interest
Tagged 1932 Scottish Mental Health Survey, 1932 Scottish Mental Survey, Alzheimer Scotland Dementia Research Centre: University of Edinburgh, BBC Health News, Centre for Cognitive Ageing and Cognitive Epidemiology: University of Edinburgh, Clustering, Dementia Risk Factors, Dementia Risk Reduction, Department of Epidemiology and Public Health (University College London), Department of Epidemiology and Public Health: UCL, Department of Medical Epidemiology and Biostatistics: Karolinska Institutet, Department of Psychology: University of Southern California, Edinburgh, Environmental Factors in Scotland, Environmental Factors in Sweden, Environmental Risk Factors, Epidemiology, Epidemiology and Statistics, Geographical Clustering, Geographical Clustering of Dementia in Scotland, Geographical Variation in Dementia, Geographical Variations in Dementia Risk, Glasgow, Greater Glasgow and Clyde Nursing Homes Medical Practice, Higher Latitudes, Karolinska Institute, Karolinska Institute in Stockholm, Karolinska Institutet, Late-Onset Dementia in the 1932 Scottish Mental Survey Cohort, Latitude (Potential Risk Factor), Los Angeles, NHS Greater Glasgow and Clyde, NHS National Services Scotland, NHS Scotland, Northern Countries, Overlapping Risk Factors, Potentially Modifiable Socio-Environmental Risk Factors for Dementia, Public Health and Intelligence: NHS National Services Scotland, Risk Factors, Scottish Dementia Clinical Research Network, Scottish Mental Survey Study, Socio-Environmental Risk Factors for Dementia, Stockholm, Sweden. Epidemiology, Sweden; Karolinska Institutet, Swedish Twin Registry, University College London (UCL), University of Edinburgh, University of Southern California, Vitamin D, Vitamin D Deficiency
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