Tag Archives: Lewy Body Degeneration

Hallucinations and Delusions in Dementia With Lewy Bodies (Behavioural Neurology)

Summary Hallucinations and delusions are common in Dementia with Lewy Bodies (DLB). A study shows that DLB patients who experience delusional symptoms tend to have poorer cognitive function and more severe BPSD. Oddly, DLB patients with diabetes appear to be less … Continue reading

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Dementia with Lewy Bodies: Updated DLB Consortium Diagnosis and Management Consensus Report (Neurology)

Summary The Dementia with Lewy Bodies (DLB) Consortium has published an updated set of recommendations on diagnosis and management of DLB. Clinical features and diagnostic biomarkers are covered, with guidance on their interpretation. Previously omitted aspects of Lewy-related pathology are … Continue reading

Posted in Antipsychotics, Diagnosis, For Doctors (mostly), For Nurses and Therapists (mostly), For Researchers (mostly), International, Management of Condition, Mental Health, Models of Dementia Care, Non-Pharmacological Treatments, Person-Centred Care, Quick Insights, UK | Tagged , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , | Leave a comment

Early Diagnosis of Parkinson’s Disease and DLB Using CSF Biomarker? (BBC News / Annals of Clinical and Translational Neurology)

Summary Research at the University of Edinburgh indicates that test for synuclein, which measures how sticky this protein molecule has become (i.e. alpha-synuclein aggregation), might be the key to diagnosing accurately the early stages of both Parkinson’s Disease and Dementia … Continue reading

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Exploring Disease-Modifying Treatments for Lewy-Body Dementia (Frontiers in Neuroscience)

Summary The authors of this review remind readers that there are currently no disease-modifying therapies for Dementia with Lewy bodies (DLB). DLB accounts for perhaps 25% of all dementia cases. This review covers therapeutic directions which have been explored for … Continue reading

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Information Resource on Lewy Body Dementia (National Institute on Aging: USA)

Summary More than 1 million Americans may be affected by Lewy Body Dementia (LBD). This information resource from the National Institute on Aging (NIA) / National Institutes of Health (NIH) in the USA has been written to assist people with … Continue reading

Posted in Antipsychotics, Charitable Bodies, Diagnosis, For Carers (mostly), For Doctors (mostly), For Nurses and Therapists (mostly), For Researchers (mostly), For Social Workers (mostly), International, Management of Condition, Non-Pharmacological Treatments, Parkinson's Disease, Patient Care Pathway, Patient Information, Person-Centred Care, Pharmacological Treatments, Practical Advice, Quick Insights, Universal Interest | Tagged , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , | Leave a comment

Treatment of Visual Hallucinations in Neurodegenerative Diseases (Future Neurology)

Summary Treatment of visual hallucinations in neurodegenerative disorders is at an early stage of development due to the underlying mechanisms being imperfectly understood. The authors consider various potential approaches to developing treatments, but caution readers that any single treatment is … Continue reading

Posted in Acute Hospitals, Antipsychotics, Community Care, For Carers (mostly), For Doctors (mostly), For Nurses and Therapists (mostly), For Researchers (mostly), Management of Condition, Mental Health, Models of Dementia Care, NHS, Non-Pharmacological Treatments, Patient Care Pathway, Pharmacological Treatments, Quick Insights, UK, Universal Interest | Tagged , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , | Leave a comment

SPECT Imaging of Suspected Dementia with Lewy Bodies (BMJ Open)

Summary This article reviews progress in the use of Single-Photon Emission Computed Tomography (SPECT) for the diagnosis of Dementia with Lewy Bodies (DLB). The authors conclude that systematic visual analyses of ((123)I)FP-CIT SPECT images may be used to detect people … Continue reading

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REM Sleep Behaviour Disorder: an Early Window on Neurodegeneration (Tremor and Other Hyperkinetic Movements)

Summary Rapid eye movement (REM) sleep behaviour disorder (RBD), involving loss of the normal atonia during REM sleep and causing patients to “act out” their dreams, offers several promising research opportunities. Patients with RBD are at high risk of developing synuclein-mediated … Continue reading

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Review and Timeline of Lewy Pathology (Nature Reviews. Neurology)

Summary This article traces developments in Lewy pathology since Fritz Heinrich Lewy’s 1912 discovery of the protein aggregates underlying Parkinson Disease (PD) in brain regions other than the substantia nigra. It was Konstantin Nikolaevich Tretiakoff who in 1919 found similar … Continue reading

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Rapid Eye Movement (REM) Sleep Behaviour Disorder May Predict Development of Dementia With Lewy Bodies (Mayo Clinic News)

Summary Rapid eye movement (REM) sleep behaviour disorder is caused by the loss of the normal muscle paralysis during REM sleep. This tendency to “act out dreams” can appear three decades or more before a formal diagnosis of dementia with Lewy bodies in males, … Continue reading

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