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Tag Archives: Mad Cow Disease
No Room For Complacency Regarding Population Subclinical vCJD? (PLoS Pathogens)
Summary After a near-miss mini-epidemic of Variant Creutzfeldt-Jakob Disease (vCJD) in the 1990s, experts caution that: “It is essential that we do not become complacent and continue both surveillance and risk management strategies in both human and animal prion diseases”. … Continue reading
Posted in Universal Interest
Tagged Biomarkers, Biotechnology and Biological Sciences Research Council (BBSRC), Blood Organ and Tissue Donation, Blood Transfusions, Blood-Based Biomarkers, Bovine Spongiform Encephalopathy (BSE), BSE Exposure, Centre for Dementia Prevention: University of Edinburgh, CJD, CJD Risk Management, CJD Surveillance, Creutzfeldt-Jakob Disease (CJD), Creuzfeldt Jacob Disease (CJD), Decontamination of Surgical Instruments, Dementia Prevention, Diack and Manson Laboratories, Donor Blood, Edinburgh Neuroscience, Edinburgh Neuroscience: University of Edinburgh, Epidemiology, Epidemiology and Statistics, Hypothetical Prodromes of Dementia, Infectivity of vCJD Infection, Mad Cow Disease, Medical Instruments, Medical Procedures, Misfolded Prion Protein (PrP), National CJD Research and Surveillance Unit (NCJDRSU), National CJD Research and Surveillance Unit: University of Edinburgh, National Institute for Health Research (NIHR) Policy Research Programme, NCJDRSU: National CJD Research and Surveillance Unit, Neurodegeneration, Neurodegenerative Disease Research, Neurodegenerative Diseases, PLoS Pathogens, Prevalence of CJD, Prion Diseases, Prionics Blood Test, Public Health, Public Health Risk, Public Health Surveillance, Roslin Institute (Edinburgh), Roslin Institute [and] R(D)SVS: University of Edinburgh, Subclinical vCJD, UK Blood Supply, University of Edinburgh, Variant CJD and Blood, Variant Creutzfeldt-Jakob Disease, vCJD Blood Testing, vCJD Carriers in UK, vCJD Infection
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Minimising CJD and vCJD Transmission Risks in Healthcare and Community Settings (Department of Health)
Summary The Advisory Committee on Dangerous Pathogens’ Transmissible Spongiform Encephalopathy (ACDP TSE) Risk Management Subgroup has released updated guidance which aims to minimise the risks of transmission of CJD and vCJD in healthcare and other public settings. Full Text Link … Continue reading
Posted in Acute Hospitals, Department of Health, For Doctors (mostly), For Nurses and Therapists (mostly), For Researchers (mostly), Guidelines, Local Interest, Management of Condition, National, NHS, Person-Centred Care, Practical Advice, Quick Insights, Standards, UK, Universal Interest
Tagged Abnormal Proteins (Prions), ACDP TSE Ophthalmic Sub-Group, Advisory Committee on Dangerous Pathogens, Advisory Committee on Dangerous Pathogens (ACDP), Advisory Committee on Dangerous Pathogens (ACDP) Transmissible Spongiform Encephalopathy (TSE) Sub Group, Advisory Committee on Dangerous Pathogens. Transmissible Spongiform Encephalopathy Agents: Alert for Urological Surgeons Regarding Equipment Used for Patients At Risk of vCJD (Transrectal Prostatic Bi, Advisory Committee on the Safety of Blood, Advisory Committee on the Safety of Blood Tissues and Organs (SaBTO), Anaesthesia and Intensive Care, Association of Anaesthetists of Great Britain and Ireland (AAGBI), Bed Linen, Blood Organ and Tissue Donation, Blood Safety, Blood Transfusions, Bovine Spongiform Encephalopathy (BSE), Childbirth, CJD, CJD and vCJD Transmission Precautions, CJD and vCJD Transmission Routes, CJD Guidance For Ophthalmologists, CJD Risk Management, CJD Surveillance, Clinical Waste, Community Healthcare of CJD Patients, Contaminated Surgical Instruments, COSHH: Control of Substances Hazardous to Health Regulations 2002, Creutzfeldt-Jakob Disease (CJD), Creuzfeldt Jacob Disease (CJD), Decontamination of Surgical Instruments, Dental Instruments, Dentistry, Distribution of Transmissible Spongiform Encephalopathy Infectivity in Human Tissues and Body Fluids, Donor Blood, Engineering and Science Advisory Committee Into the Decontamination of Surgical Instruments Including Prion Removal (ESAC-Pr), Enhanced Surveillance: At Risk Individuals, FFI: Fatal Familial Insomnia, FSE: Feline Spongiform Encephalopathy, GSS: Gerstmann Sträussler Scheinker Disease, Guidelines for Handling Tissues From Patients With or At Risk of CJD or vCJD, Haematology, Haemovigilance, Health and Safety Management of Transmissible Spongiform Encephalopathy, HGH: Human Growth Hormone, Hospital Care of CJD Patients, Infection and Infectious Diseases, Infection Control of CJD vCJD and Other Human Prion Diseases in Healthcare and Community Settings, Joint United Kingdom Blood Transfusion and Tissue Transplantation Services Professional Advisory Committee (JPAC), Mad Cow Disease, Management of Instruments and Tissues From Brain Biopsy Procedures on Patients With Progressive Neurological Disorders, MBM: Meat and Bone Meal, Medical Instruments, Medical Procedures, Minimising CJD and vCJD Transmission Risks, Neurodegenerative Diseases, NHS Blood and Transplant (NHSBT), Novel Pathogens, Occupational Exposure, Parliament, Pathogens, Pregnancy, Public Health, Royal College of Ophthalmologists and the Advisory Committee on Dangerous Pathogens TSE Working Group: CJD Guidance For Ophthalmologists, Safe Working and the Prevention of Infection: Laboratory Containment and Control Measures, SBO: Specified Bovine Offal, Spillages, Standing Advisory Committee for Transfusion Transmitted Infections, Surgical Transmission of Prions, Surveillance, Tissues and Organs (SaBTO), TME: Transmissible Mink Encephalopathy, Transfusion-Transmitted Infection, Transmissible Spongiform Encephalopathies: Diagnostic Criteria, Transmissible Spongiform Encephalopathies: Distribution of Infectivity in Animal Tissue and Body Fluids, Transmissible Spongiform Encephalopathy (ACDP TSE) Risk Management Subgroup, Transmissible Spongiform Encephalopathy Agents, Transmissible Spongiform Encephalopathy Agents: Abbreviations, Transmissible Spongiform Encephalopathy Agents: After Death, Transmissible Spongiform Encephalopathy Agents: Assessment Before Surgery and or Endoscopy to Identify Patients With or At Risk of CJD or vCJD, Transmissible Spongiform Encephalopathy Agents: Endoscopy, Transmissible Spongiform Encephalopathy Agents: Frequently Asked Questions, Transmissible Spongiform Encephalopathy Agents: General Principles of Decontamination and Waste Disposal, Transmissible Spongiform Encephalopathy Agents: Guidelines for Pathologists and Pathology Laboratories, Transmissible Spongiform Encephalopathy Agents: Information Sheet for Funeral Directors Relatives and Others Following a CJD Death, Transmissible Spongiform Encephalopathy Agents: Managing CJD or vCJD Risk in Ophthalmology, Transmissible Spongiform Encephalopathy Agents: Managing vCJD Risk in General Surgery and Liver Transplantation, Transmissible Spongiform Encephalopathy Agents: Quarantining of Surgical Instruments, Transmissible Spongiform Encephalopathy Agents: Safe Working and the Prevention of Infection, Transmissible Spongiform Encephalopathy Agents: Transport of Transmissible Spongiform Encephalopathy-Infected Material, Transport of Transmissible Spongiform Encephalopathy-Infected Material, TSE Risk Assessment Subgroup of the Advisory Committee on Dangerous Pathogens, UK Blood Safety, UK Blood Services, UK Blood Services Joint Professional Advisory Committee, UK Blood Supply, Variant CJD and Blood, Variant Creutzfeldt-Jakob Disease, vCJD Blood Testing, vCJD Carriers in UK, vCJD Infection
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Evolutionary Mutation of Human Prion Protein May Prevent Prion Diseases? (NHS Choices / BBC News / Nature)
Summary A natural human mutation (called V127) in the gene encoding prion protein may offer resistance to CJD. A study using mice with this genetic mutation appears to confirm resistance to prion diseases. This finding may in future help in … Continue reading
Posted in Animal Studies, BBC News, For Doctors (mostly), For Researchers (mostly), In the News, International, NHS Digital (Previously NHS Choices), Quick Insights, Universal Interest
Tagged Abnormal Prion Protein, Abnormal Proteins (Prions), BBC Health News, Behind the Headlines, Bovine Spongiform Encephalopathy (BSE), Brain-Eating Cannibals (Mortuary Feasts), CJD, Colorado State University, Creutzfeldt Jacob Disease (CJD), Creutzfeldt-Jakob Disease (CJD), Department of Neurodegenerative Disease: UCL Institute of Neurology, Evolved Protection Against Human Prions, Familial or Inherited CJD, Fore People (Tribe in Papua New Guinea), Kuru, M129V, Mad Cow Disease, Medical Research Council (MRC), Mice With Prion Disease Similar to Cruetzfeldt-Jakob Disease (CJD), Misfolded Prion Protein (PrP), Misfolded Proteins, MRC Prion Unit, MRC Prion Unit: UCL Institute of Neurology, Nature, Neurodegeneration, Neurodegenerative Disease Research, Neurodegenerative Diseases, Neuroprotection, Neuroprotection Research, Papua New Guinea, Papua New Guinea Institute of Medical Research, Prion Diseases, Prion Protein, Prion Protein (PrP) Variant G127V, Prion Protein Gene, Prion Research Center: Colorado State University, Prion-Infected Mice, Prof John Collinge: Medical Research Council's Prion Unit at University College London, Protective Prion Protein Variant, Sporadic CJD, Transgenic Mice, UCL Institute of Neurology, United States, University College London (UCL), USA, V127 Gene: Resistance to Prion Diseases, Variant CJD, vCJD Infection
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Risks of Variant Creutzfeldt-Jakob Disease: UK Blood Safety (Department of Health)
Summary This document presents the Government’s response to the Science and Technology Select Committee’s “After the Storm?” report on blood safety. It sets out the government’s commitment to evidence-based and cost effective ways to reduce risks of infection from blood transfusions, … Continue reading
Posted in Acute Hospitals, Community Care, Department of Health, For Doctors (mostly), For Nurses and Therapists (mostly), For Researchers (mostly), In the News, National, NHS, Non-Pharmacological Treatments, Patient Care Pathway, Quick Insights, Standards, UK
Tagged Abnormal Proteins (Prions), Advisory Committee on Dangerous Pathogens, Advisory Committee on Dangerous Pathogens (ACDP), Advisory Committee on Dangerous Pathogens (ACDP) Transmissible Spongiform Encephalopathy (TSE) Sub Group, Advisory Committee on the Safety of Blood, Advisory Committee on the Safety of Blood Tissues and Organs (SaBTO), After the Storm?, Behavioural Deferrals for Potential Blood Donors, Blood Organ and Tissue Donation, Blood Safety, Blood Transfusions, Bovine Spongiform Encephalopathy (BSE), CJD, CJD Resource Centre Oversight Committee, CJD Risk Management, CJD Surveillance, Contaminated Surgical Instruments, Creutzfeldt-Jakob Disease (CJD), Creuzfeldt Jacob Disease (CJD), Decontamination of Surgical Instruments, Donor Blood, DuPont’s Rely+On Prion Inactivator, Enhanced Surveillance: At Risk Individuals, Epidemiology, Epidemiology and Statistics, Haematology, Haemovigilance, House of Commons, House of Commons Science and Technology Committee, Infection and Infectious Diseases, Joint United Kingdom Blood Transfusion and Tissue Transplantation Services Professional Advisory Committee (JPAC), Mad Cow Disease, Medical Instruments, Medical Procedures, Medicines and Healthcare Products Regulatory Agency (MHRA), Misfolded Prion Protein (PrP), MRC Prion Unit, MRC Prion Unit Blood Test, National CJD Research and Surveillance Unit (NCJDRSU), National Expert Panel on New and Emerging Infections, National Institute of Biological Standards and Controls (NIBSC), NCJDRSU: National CJD Research and Surveillance Unit, Neurodegeneration, Neurodegenerative Disease Research, Neurodegenerative Diseases, NHS Blood and Transplant (NHSBT), Novel Pathogens, Parliament, Pathogens, PHE: Public Health England, Population-Level Risk Assessment, Prevalence of CJD, Prion Diseases, Prion Filtration, Prion Inactivation, ProMetic’s P-Capt Prion Filter, Public Health, Public Health England (PHE), Public Health Surveillance, Rapid Review Panel (RRP), Science and Technology Committee (House of Commons), Scientific Advisory Committee (SAC), Scottish National Blood Transfusion Service (SNBTS), Serious Hazards of Transfusion (SHOT), Spongiform Encephalopathy Advisory Committee (SEAC), Standing Advisory Committee for Transfusion Transmitted Infections, Surgical Transmission of Prions, Surveillance, Tissues and Organs (SaBTO), Transfusion-Transmitted Infection, UK Blood Safety, UK Blood Services, UK Blood Services Joint Professional Advisory Committee, UK Blood Supply, UK Parliament, United Kingdom Haemophilia Centre Doctors’ Organisation (UKHCDO), Variant CJD and Blood, Variant Creutzfeldt-Jakob Disease, vCJD Blood Testing, vCJD Carriers in UK, vCJD Clinical Governance Advisory Group, vCJD Infection
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Potential Transmission of vCJD (BBC News / House of Commons Science and Technology Committee / SaBTO)
Summary The House of Commons Science and Technology Committee has asserted that the government has a too casual approach to the human form of mad cow disease. Roughly one in 2,000 people in the UK could be a carrier of … Continue reading
Posted in BBC News, Department of Health, Department of Health and Social Care (DHSC), In the News, National, NHS, Quick Insights, Standards, Statistics, UK, Universal Interest
Tagged Abnormal Proteins (Prions), Advisory Committee on Dangerous Pathogens, Advisory Committee on Dangerous Pathogens (ACDP), Advisory Committee on Dangerous Pathogens (ACDP) Transmissible Spongiform Encephalopathy (TSE) Sub Group, Advisory Committee on the Safety of Blood, Advisory Committee on the Safety of Blood Tissues and Organs (SaBTO): Paediatric Components Working Group (PCWG), After the Storm?, Apheresis Platelets, BBC Health News, Behavioural Deferrals for Potential Blood Donors, Blood Organ and Tissue Donation, Blood Transfusions, Bovine Spongiform Encephalopathy (BSE), BSE Exposure, CJD, CJD Risk Management, CJD Surveillance, Creutzfeldt-Jakob Disease (CJD), Creuzfeldt Jacob Disease (CJD), Decontamination of Surgical Instruments, Department of Health and Social Care, Donor Blood, DuPont’s Rely+On Prion Inactivator, Enhanced Surveillance: At Risk Individuals, Epidemiology, Epidemiology and Statistics, House of Commons, House of Commons Science and Technology Committee, Importation of Plasma and Provision of Apheresis Platelets, Infection and Infectious Diseases, Mad Cow Disease, Medical Instruments, Medical Procedures, Medical Research Council's Prion Unit at University College London, Medicines and Healthcare Products Regulatory Agency (MHRA), Misfolded Prion Protein (PrP), MRC Prion Unit, MRC Prion Unit and Department of Neurodegenerative Disease: UCL Institute of Neurology, MRC Prion Unit Blood Test, National CJD Research and Surveillance Unit (NCJDRSU), National Expert Panel on New and Emerging Infections, National Institute of Biological Standards and Controls (NIBSC), NCJDRSU: National CJD Research and Surveillance Unit, Neurodegeneration, Neurodegenerative Disease Research, Neurodegenerative Diseases, Neurological Disorders, OctaplasLG, Paediatric Components Working Group (PCWG) of Advisory Committee on the Safety of Blood Tissues and Organs (SaBTO), Parliament, Prevalence of CJD, Prion Diseases, Prion Filtration, Prion Protein Gene, Prion Unit Institute of Neurology: University College London, Prionics Blood Test, ProMetic’s P-Capt Prion Filter, Public Health, Public Health Surveillance, Rapid Review Panel (RRP), Risk Reduction Measures for Variant Creutzfeldt-Jakob Disease (PCWG Report), SaBTO’s Relationship With Government, Science and Technology Committee (House of Commons), Scientific Advisory Committee (SAC), Surgical Transmission of Prions, Surveillance, Thrombotic Thrombocytopenic Purpura (TTP), Tissues and Organs (SaBTO), UK Blood Services Joint Professional Advisory Committee, UK Blood Supply, UK Parliament, Variant CJD and Blood, Variant Creutzfeldt-Jakob Disease, vCJD Blood Testing, vCJD Carriers in UK, vCJD Infection
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Blood Donation and Transmission of vCJD: Inquiry Required? (BBC News)
Summary The Commons Science and Technology Committee has called for an independent inquiry to check the safety of donor blood arising from the hidden risk of infection from variant CJD (the human form of “mad cow disease”). A recent study revealed one in 2,000 Britons … Continue reading
Posted in BBC News, In the News, National, NHS, Quick Insights, UK, Universal Interest
Tagged Abnormal Proteins (Prions), BBC Health News, Blood Organ and Tissue Donation, Blood Transfusions, Bovine Spongiform Encephalopathy (BSE), CJD, Creutzfeldt-Jakob Disease (CJD), Creuzfeldt Jacob Disease (CJD), Donor Blood, Epidemiology, Epidemiology and Statistics, House of Commons Science and Technology Committee, Mad Cow Disease, Medical Instruments, Medical Procedures, Misfolded Prion Protein (PrP), Neurodegeneration, Neurodegenerative Disease Research, Neurodegenerative Diseases, NHS Blood and Transplant (NHSBT), Prevalence of CJD, Prion Diseases, Public Health, Public Health England (PHE), Public Health Surveillance, Surveillance, Variant CJD and Blood, Variant Creutzfeldt-Jakob Disease, vCJD Carriers in UK, vCJD Infection
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Estimates of vCJD Carriers in UK Double (BBC News / NHS Choices / BMJ)
Summary A study of 32,000 human appendix samples from 41 hospitals in the UK indicates that 1 in 2,000 British people may be carrying the abnormal prions associated with variant CJD (the human form of “mad cow” disease). It is … Continue reading
Posted in Acute Hospitals, BBC News, Community Care, For Carers (mostly), For Doctors (mostly), For Nurses and Therapists (mostly), For Researchers (mostly), In the News, National, NHS Digital (Previously NHS Choices), Quick Insights, Statistics, UK, Universal Interest
Tagged Abnormal Proteins (Prions), Animal Health and Veterinary Laboratories Agency, BBC Health News, Behind the Headlines, Blood Transfusions, BMJ, Bovine Spongiform Encephalopathy (BSE), British Medical Journal (BMJ), CJD, Creutzfeldt-Jakob Disease (CJD), Creuzfeldt Jacob Disease (CJD), Department of Neurodegenerative Disease: UCL Institute of Neurology, Derriford Hospital, Division of Neuropathology: UCL Institute of Neurology, Epidemiology, Epidemiology and Statistics, Mad Cow Disease, Misfolded Prion Protein (PrP), MRC Prion Unit and Department of Neurodegenerative Disease: UCL Institute of Neurology, National Centre for Infectious Disease Surveillance and Control: Public Health England, National CJD Research and Surveillance Unit (NCJDRSU), National Creutzfeldt-Jakob Disease Research and Surveillance Unit, National Hospital for Neurology and Neurosurgery: UCL Institute of Neurology, NCJDRSU: National CJD Research and Surveillance Unit, Neurodegeneration, Neurodegenerative Disease Research, Neurodegenerative Diseases, Prevalence of CJD, Prion Diseases, Public Health England (PHE), TSE Risk Assessment Subgroup of the Advisory Committee on Dangerous Pathogens, UCL Institute of Neurology, University College London Institute of Neurology, University of Edinburgh, Variant CJD and Blood, Variant Creutzfeldt-Jakob Disease, vCJD Carriers in UK, vCJD Infection
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