Tag Archives: Magnetic Resonance Imaging (MRI)

Dementia Biomarkers Re-Explored? (General Psychiatry / JGCR)

Summary A recent systematic review examines biomarkers, as strictly defined, for neurodegenerative diseases. “Vast improvements in neuroimaging techniques have led to newly discovered biomarkers and diagnostics”. p.5 Behavioural biomarkers are mentioned hardly at all. Full Text Link Reference Maclin, JMA. … Continue reading

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Middle-Age Obesity and Accelerated Brain Ageing (BBC News / Neurobiology of Aging)

Summary Researchers at the Cambridge Centre for Ageing and Neuroscience, examining the loss of white matter in the brains of lean and overweight persons, have discovered that the brains of overweight people tend to resemble those of leaner people who … Continue reading

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Glasgow Coma Scale Update (Nursing Times / BBC News / PLoS Computational Biology / Nature Communications)

Summary The Glasgow Coma Scale has been updated forty years after its initial implementation. This Nursing Times article reviews the variations in technique which have developed since then, the scale’s current composition and application and the “structured approach” to the … Continue reading

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Blood Test Potentially Able to Predict Alzheimer’s Disease Onset (BBC News / Alzheimer’s & Dementia)

Summary Research published in the Alzheimer’s & Dementia: the Journal of the Alzheimer’s Association may indicate a significant step forwards in developing a blood test which could be able to predict the risk of Alzheimer’s Disease onset with 87% accuracy. Research … Continue reading

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UK Biobank: Ambitious Imaging Data Collection (BBC News / European Psychiatry)

Summary Around 100,000 of the 500,000 adults aged 40-69 and currently enrolled in UK Biobank are to be invited to take part in detailed imaging of their brain, heart and other major organs. This will be the world’s biggest scanning … Continue reading

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Appropriate Use of Neuroimaging in Dementia Diagnosis (Ontario Health Technology Assessment Series / BBC News)

Summary This economic literature review and cost-effectiveness analysis investigated neuroimaging for diagnostic purposes, and in particular examined whether computed tomography (CT) or magnetic resonance imaging (MRI) should be used. It was not possible to answer the specific research questions with … Continue reading

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Biomarker Assessments in Alzheimer’s Disease Clinical Trials (Quintiles / Frontiers in Aging Neuroscience)

Summary Accurate and sensitive tools are required for the early detection / diagnosis of Alzheimer’s Disease, particularly to assist research. Alzheimer’s Disease clinical trials make increasing use of biomarkers, particularly neuroimaging markers and cerebrospinal fluid (CSF) biomarkers obtained via invasive … Continue reading

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Recent Systematic Reviews and Meta-Analyses on Brain Imaging

Summary Recent reviews and meta-analyses on imaging-related topics are listed below. Some of these articles are available freely. Obtaining the full-text of the other articles requires a suitable Athens password, a journal subscription or payment per access. The Bibliographic Citations … Continue reading

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Cognitive and Neuroimaging Predictors of Progression from Mild Cognitive Impairment to Dementia (NHS Choices / Journal of Alzheimer’s Disease)

Summary The detection of pre-clinical Alzheimer’s Disease appears to be accomplished best by the use of a combination of information, taken from targeted neuroimaging and complementary neuropsychological assessments of cognitive functioning. This combination of approaches may be necessary in order to … Continue reading

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