Tag Archives: Mayo Clinic: Rochester

Time for a Complete Reset in Alzheimer’s Disease / Dementia Drugs Research: Never Too Late? (BBC News / Brain / NHS Digital)

Posted on May 1, 2019 by Dementia and Elderly Care News

Summary A new type of dementia, previously misdiagnosed as Alzheimer’s Disease, has been discovered to be prevalent in the oldest of old persons. Perhaps a third of elderly people earlier thought to have Alzheimer’s Disease may have had Limbic-predominant age-related … Continue reading →

Posted in BBC News, Diagnosis, For Doctors (mostly), For Nurses and Therapists (mostly), For Researchers (mostly), In the News, International, NHS Digital (Previously NHS Choices), Pharmacological Treatments, Quick Insights, UK, Universal Interest | Tagged Amnestic MCI, Australia, Austria, Bazian, BBC Health News, Behind the Headlines, Brain (Journal), Central Clinical School Faculty of Medicine and Health (Sydney Australia), Clinical and Neurocognitive Features of LATE, Consensus Guidelines for LATE-NC Staging, Consensus Proposed LATE-NC TDP-43 Stages, Dementia-Related Misdiagnosis, Differential Diagnosis, Drug Trials, Drug Trials Failure Rate, Emory University (Atlanta), FTLD-TDP: Frontotemporal Lobar Degeneration With TDP-43 Proteinopathy, Harvard University, Hippocampal Atrophy, Illinois Institute of Technology, Institute of Neurology: Medical University of Vienna, Japan, LATE Biomarkers, LATE Neuropathological Change (LATE-NC), LATE Working Group, Limbic-Predominant Age-Related TDP-43 Encephalopathy (LATE), Mayo Clinic (Jacksonville), Mayo Clinic: Rochester, Medical University of Vienna, Misdiagnosis, Misdiagnosis (Potential), Neurodegenerative Disease Research, Neurodegenerative Diseases, Neurodegenerative Disorders, Neuropathology, Neuropathology in FTLD-tau and FTLD-TDP, Newcastle University, NHS Digital (Formerly NHS Choices), Oldest Old, Oldest Old Age, Oldest People With Dementia, Prevalence of Dementia in Oldest Old, Public Health Impact of LATE, Recommendations for Routine Autopsy Evaluation and Classification of LATE-NC, Rush University Medical Center, Stanford University, Subtypes of Dementia, Sweden, TDP-43 Protein, TDP-43 Proteinopathy, Tokyo Metropolitan Geriatric Hospital and Institute of Gerontology, United States, University of California, University of Cambridge, University of Kentucky, University of Minnesota, University of Pennsylvania, University of Southern California, University of Sydney Brain and Mind Centre, University of Texas Southwestern Medical Center, University of Washington, Uppsala University, USA | Leave a comment

Mid-Life Blood Test for Inflammation May Predict Later-Life Dementia Risk? (NHS Choices / Neurology)

Posted on November 5, 2017 by Dementia and Elderly Care News

Summary Higher inflammatory marker scores in middle age, based on five blood-based markers of inflammation (fibrinogen, albumin, von Willebrand factor, factor VIII and white blood cell count) appear to be associated with reduced brain volume (thought to be neurodegenerative “shrinkage”) … Continue reading →

Posted in For Doctors (mostly), For Nurses and Therapists (mostly), For Researchers (mostly), In the News, International, NHS Digital (Previously NHS Choices), Quick Insights, Universal Interest | Tagged AD Signature Region Volume (Shrinkage), Albumin, ARIC Study: Atherosclerosis Risk in Communities, Atherosclerosis Risk in Communities (ARIC) Study, Baylor College of Medicine, Bazian, Behind the Headlines, Biomarker Development, Biomarkers, Biomarkers for Inflammation, Biomarkers Research Programmes, Blood-Based Biomarkers, Blood-Based Biomarkers of Pre-Symptomatic Alzheimer’s Disease, Brain Shrinkage, Brain Volume, Center for Cardiovascular Disease Prevention: Houston Methodist DeBakey Heart and Vascular Center, Critical Appraisals, Department of Medicine: University of Mississippi Medical Center, Departments of Neurology and Epidemiology: Johns Hopkins University School of Medicine, Departments of Neurology and Radiology: Mayo Clinic (Rochester), Division of Epidemiology and Community Health: University of Minnesota, Factor VIII, Fibrinogen, Hippocampal Volume, Hippocampal Volume (Memory Related), Hippocampus (Shrinkage in Late Adulthood), Houston Methodist DeBakey Heart and Vascular Center (Texas), Immune System, Immune System and Neurodegenerative Diseases, Inflammation, Inflammation and Neurodegenerative Diseases, Inflammatory Response, Johns Hopkins University School of Medicine, Mayo Clinic, Mayo Clinic: Rochester, Neurodegenerative Disease Research, Neurodegenerative Diseases, Neurodegenerative Disorders, Neurology (Journal), Occipital Lobe Volume (Shrinkage), Plasma Biomarkers, Preclinical Biomarkers and Dementia, Preclinical Biomarkers in Alzheimer's Disease, School of Public Health: University of Minnesota, Section of Cardiology: Baylor College of Medicine, Section of Cardiology: Baylor College of Medicine. Baylor College of Medicine, Systemic Inflammation, Systemic Inflammation and Neurodegeneration, United States, University of Minnesota, University of Mississippi Medical Center, University of Mississippi Medical Centre, US National Heart Lung and Blood Institute, USA, von Willebrand Factor, White Blood Cell Count | Leave a comment

Fourth Annual Deep Brain Stimulation (DBS) Think Tank (Frontiers in Integrative Neuroscience / International Journal of Neuroscience)

Posted on December 15, 2016 by Dementia and Elderly Care News

Summary An annual round-up of developments in the field of Deep Brain Stimulation (DBS). (x3). Full Text Link Reference Deeb, W. Giordano, JJ. [and] Rossi, PJ. [et al] (2016). Proceedings of the Fourth Annual Deep Brain Stimulation Think Tank: a … Continue reading →

Alzheimer’s Disease Biomarkers: Updated Hypothetical Model (Lancet Neurology)

Posted on April 18, 2014 by Dementia and Elderly Care News

Summary A hypothetical model of the major biomarkers of Alzheimer’s Disease, published by the same authors in 2010, has been updated in the light of new evidence. Full Text Link Reference Jack, CR. Jr. Knopman, DS. [and] Jagust, WJ. [et … Continue reading →

Posted in Diagnosis, For Doctors (mostly), For Researchers (mostly), International, Systematic Reviews | Tagged Aβ, Aβopathy, Aβopathy Acceleration of Antecedent Tauopathy, Alzheimer's Disease: Hypothetical Model(s), Alzheimer’s Disease Biomarkers, Amyloid, Amyloid Beta, Amyloid Beta Protein, Amyloid Proteins, Amyloid-β (Aβ), Apolipoprotein E, Beta-Amyloid, Beta-Amyloid Plaques, Biomarker Assessments in Alzheimer’s Disease, Biomarkers, Biomarkers Predicting Cognitive Decline and Alzheimer's Disease, Brain Beta Amyloid Load, Brain Deposition of Amyloid, Cerebrospinal Fluid, Cerebrospinal Fluid (CSF), Clearance of Amyloid Beta Protein, Cognitive Impairment, Cognitive Response to Progression of Pathophysiology, CSF Aβ, CSF Biomarkers, CSF Tau, Department of Biomedical Statistics and Informatics: Mayo Clinic (Rochester), Department of Neurology: Mayo Clinic (Rochester), Department of Neurosciences: University of California-San Diego, Department of Radiology: Mayo Clinic (Rochester), Early Detection of Alzheimer’s Disease, Early Diagnosis of Alzheimer's Disease, Fluid and Imaging Biomarkers, Indexing Subjects by Time, Inter-Subject Variability, β-amyloid, β-Amyloid 1-42 (Aβ42), Lancet Neurology, Longitudinal Population Studies of Diagnostic Biomarkers, Mayo Clinic: Rochester, Metabolic FDG-PET, Molecular PIB-PET, Neurodegeneration, Neurofibrillary Tangles (NFTs), Neuroimaging, Neuroimaging of Dementia, Neuroimaging Tools, Ordering of Alzheimer's Disease Biomarkers, Pathophysiological Processes in Alzheimer’s Disease, Positron Emission Tomography (PET), Preclinical Alzheimer's Disease, Prodromal Alzheimer's Disease, Proteinopathies, School of Public Health and Helen Wills Neuroscience Institute: University of California, Sequence of Pathological Events in Alzheimer’s Disease, Structural MRI, Tau, Tau Pathology, Tau Protein, Temporal Evolution of Alzheimer’s Disease Biomarkers, Temporal Ordering of Biomarkers, Test to Detect Early-Stage Alzheimer’s Disease, United States, University of California, University of Pathology and Laboratory Medicine and Institute on Aging: University of Pennsylvania, University of Pennsylvania School of Medicine, USA, Veterans Affairs and University of California | Leave a comment

Tag Archives: Mayo Clinic: Rochester

Fourth Annual Deep Brain Stimulation (DBS) Think Tank (Frontiers in Integrative Neuroscience / International Journal of Neuroscience)

Alzheimer’s Disease Biomarkers: Updated Hypothetical Model (Lancet Neurology)

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