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- Dementia-Friendly Communities Provision, Viewed as a Social Determinant of Health (JGCR / NHS England / WHO)
- International Perspectives on the Possible Impact of the COVID-19 Pandemic and Lockdown on Abuse of the Elderly (JGCR / American Journal of Geriatric Psychiatry / JAGS)
- Updates Relating to the Lancet Commission on Dementia Prevention, Intervention, and Care (Lancet / Alzheimer’s Research and Therapy / Alzheimer’s and Dementia)
- A Brief Review of How the COVID-19 Pandemic Relates to Elderly Care and Research (JGCR)
- Some Speculated / Potential Benefits of COVID-19 (JGCR / BBC Radio 4’s Rethink / BGS)
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Tag Archives: Mayo Clinic: Rochester
Time for a Complete Reset in Alzheimer’s Disease / Dementia Drugs Research: Never Too Late? (BBC News / Brain / NHS Digital)
Summary A new type of dementia, previously misdiagnosed as Alzheimer’s Disease, has been discovered to be prevalent in the oldest of old persons. Perhaps a third of elderly people earlier thought to have Alzheimer’s Disease may have had Limbic-predominant age-related … Continue reading →
Posted in BBC News, Diagnosis, For Doctors (mostly), For Nurses and Therapists (mostly), For Researchers (mostly), In the News, International, NHS Digital (Previously NHS Choices), Pharmacological Treatments, Quick Insights, UK, Universal Interest
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Tagged Amnestic MCI, Australia, Austria, Bazian, BBC Health News, Behind the Headlines, Brain (Journal), Central Clinical School Faculty of Medicine and Health (Sydney Australia), Clinical and Neurocognitive Features of LATE, Consensus Guidelines for LATE-NC Staging, Consensus Proposed LATE-NC TDP-43 Stages, Dementia-Related Misdiagnosis, Differential Diagnosis, Drug Trials, Drug Trials Failure Rate, Emory University (Atlanta), FTLD-TDP: Frontotemporal Lobar Degeneration With TDP-43 Proteinopathy, Harvard University, Hippocampal Atrophy, Illinois Institute of Technology, Institute of Neurology: Medical University of Vienna, Japan, LATE Biomarkers, LATE Neuropathological Change (LATE-NC), LATE Working Group, Limbic-Predominant Age-Related TDP-43 Encephalopathy (LATE), Mayo Clinic (Jacksonville), Mayo Clinic: Rochester, Medical University of Vienna, Misdiagnosis, Misdiagnosis (Potential), Neurodegenerative Disease Research, Neurodegenerative Diseases, Neurodegenerative Disorders, Neuropathology, Neuropathology in FTLD-tau and FTLD-TDP, Newcastle University, NHS Digital (Formerly NHS Choices), Oldest Old, Oldest Old Age, Oldest People With Dementia, Prevalence of Dementia in Oldest Old, Public Health Impact of LATE, Recommendations for Routine Autopsy Evaluation and Classification of LATE-NC, Rush University Medical Center, Stanford University, Subtypes of Dementia, Sweden, TDP-43 Protein, TDP-43 Proteinopathy, Tokyo Metropolitan Geriatric Hospital and Institute of Gerontology, United States, University of California, University of Cambridge, University of Kentucky, University of Minnesota, University of Pennsylvania, University of Southern California, University of Sydney Brain and Mind Centre, University of Texas Southwestern Medical Center, University of Washington, Uppsala University, USA
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Mid-Life Blood Test for Inflammation May Predict Later-Life Dementia Risk? (NHS Choices / Neurology)
Summary Higher inflammatory marker scores in middle age, based on five blood-based markers of inflammation (fibrinogen, albumin, von Willebrand factor, factor VIII and white blood cell count) appear to be associated with reduced brain volume (thought to be neurodegenerative “shrinkage”) … Continue reading →
Posted in For Doctors (mostly), For Nurses and Therapists (mostly), For Researchers (mostly), In the News, International, NHS Digital (Previously NHS Choices), Quick Insights, Universal Interest
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Tagged AD Signature Region Volume (Shrinkage), Albumin, ARIC Study: Atherosclerosis Risk in Communities, Atherosclerosis Risk in Communities (ARIC) Study, Baylor College of Medicine, Bazian, Behind the Headlines, Biomarker Development, Biomarkers, Biomarkers for Inflammation, Biomarkers Research Programmes, Blood-Based Biomarkers, Blood-Based Biomarkers of Pre-Symptomatic Alzheimer’s Disease, Brain Shrinkage, Brain Volume, Center for Cardiovascular Disease Prevention: Houston Methodist DeBakey Heart and Vascular Center, Critical Appraisals, Department of Medicine: University of Mississippi Medical Center, Departments of Neurology and Epidemiology: Johns Hopkins University School of Medicine, Departments of Neurology and Radiology: Mayo Clinic (Rochester), Division of Epidemiology and Community Health: University of Minnesota, Factor VIII, Fibrinogen, Hippocampal Volume, Hippocampal Volume (Memory Related), Hippocampus (Shrinkage in Late Adulthood), Houston Methodist DeBakey Heart and Vascular Center (Texas), Immune System, Immune System and Neurodegenerative Diseases, Inflammation, Inflammation and Neurodegenerative Diseases, Inflammatory Response, Johns Hopkins University School of Medicine, Mayo Clinic, Mayo Clinic: Rochester, Neurodegenerative Disease Research, Neurodegenerative Diseases, Neurodegenerative Disorders, Neurology (Journal), Occipital Lobe Volume (Shrinkage), Plasma Biomarkers, Preclinical Biomarkers and Dementia, Preclinical Biomarkers in Alzheimer's Disease, School of Public Health: University of Minnesota, Section of Cardiology: Baylor College of Medicine, Section of Cardiology: Baylor College of Medicine. Baylor College of Medicine, Systemic Inflammation, Systemic Inflammation and Neurodegeneration, United States, University of Minnesota, University of Mississippi Medical Center, University of Mississippi Medical Centre, US National Heart Lung and Blood Institute, USA, von Willebrand Factor, White Blood Cell Count
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Fourth Annual Deep Brain Stimulation (DBS) Think Tank (Frontiers in Integrative Neuroscience / International Journal of Neuroscience)
Summary An annual round-up of developments in the field of Deep Brain Stimulation (DBS). (x3). Full Text Link Reference Deeb, W. Giordano, JJ. [and] Rossi, PJ. [et al] (2016). Proceedings of the Fourth Annual Deep Brain Stimulation Think Tank: a … Continue reading →
Posted in Depression, For Doctors (mostly), For Researchers (mostly), International, Mental Health, Non-Pharmacological Treatments, Parkinson's Disease, Quick Insights
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Tagged Allegheny General Hospital Pittsburgh, Alpert Medical School: Brown University Providence, Alzheimer's Disease, Asia Pacific Centre for Neuromodulation: Queensland Brain Institute, Barrow Neurological Institute: St. Joseph's Hospital and Medical Center, Basolateral Nucleus of the Amygdala, Baylor College of Medicine Houston, Brown University Providence, Center for Movement Disorders and Neurorestoration: University of Florida, Center for Neuromodulation: New York University Langone Medical Center New York, Centers for Medicare and Medicaid Services, Centromedian Thalamus, Clinical Assessment and Management of Tremor, Closed Loop Systems, Closed-Loop DBS, Crayton Pruitt Family Department of Biomedical Engineering: University of Florida, DARPA-SUBNETS: Defense Advanced Research Projects Agency - Systems-Based Neurotechnology for Emerging Therapies, Deep Brain Stimulation, Deep Brain Stimulation (DBS), Deep Brain Stimulation for the Treatment of Alzheimer Disease, Deep Brain Stimulation for the Treatment of Dementia, Deep Brain Stimulation in Parkinson's Disease, Defense Advanced Research Projects Agency (Darpa), Department of Bioengineering, Department of Biomedical Engineering: Duke University, Department of Neurology and Neuroethics Studies Program: Georgetown University Medical Center Washington, Department of Neurology: Alpert Medical School Brown University Providence, Department of Neurology: Baylor College of Medicine Houston, Department of Neurology: Mayo Clinic (Rochester), Department of Neurology: New York University Langone Medical Center New York, Department of Neurology: University Clinic of Würzburg, Department of Neurology: University of California San Francisco, Department of Neurology: University of Florida, Department of Neurosurgery: New York University Langone Medical Center New York, Department of Neurosurgery: University of Kentucky Chandler Medical Center Lexington, Department of Psychiatry: Massachusetts General Hospital Boston, Departments of Neurological Sciences: Rush University Medical Center Chicago, Diffusion Tensor Imaging, Drug Addiction, Duke University, Electrical Current Shaping, Electrocorticogram, Emory University School of Medicine (Atlanta), Epilepsy, Fludeoxyglucose, Focused Ultrasound, Food and Drug Administration, Fourth Annual Deep Brain Stimulation (DBS) Think Tank, Frontiers in Integrative Neuroscience, Georgetown University Medical Center Washington, Germany, High Frequency Stimulation, Humanitarian Device Exemption, International Deep Brain Stimulation Registry and Database for Gilles de la Tourette Syndrome, International Journal of Neuroscience, Investigational Device Exemption, Johns Hopkins Bayview Medical Center, Johns Hopkins School of Medicine Baltimore, Johns Hopkins University School of Medicine Baltimore, Kavli Institute for Fundamental Neuroscience: University of California, Local Field Potential, Local Field Potentials (LFPs), Low Frequency Stimulation, Massachusetts General Hospital (Boston), Mayo Clinic: Rochester, MCI: Mild Cognitive Impairment, Medial Prefrontal Cortex, Medtronic Modulation Minneapolis (USA), Mild Cognitive Impairment (MCI), Movement Disorders Program: Alpert Medical School, National Neurotechnology Initiative, Netherlands, Neurodegeneration, Neurodegenerative Diseases, Neuroimaging, Neuroimaging of Dementia, Neurological Disease, Neurological Information Non-Discrimination Act, Neurology, Neuropsychology, New York University: Langone Medical Center New York, NSF Engineering Research Center for Sensorimotor Neural Engineering (Seattle), Obesity, Obsessive-Compulsive Disorder, Pellegrino Center for Clinical Bioethics: Georgetown University Medical Center Washington, Post-Traumatic Stress Disorder, Psychiatry and Behavioral Sciences: Johns Hopkins Bayview Medical Center, Queensland Brain Institute: University of Queensland Brisbane, Responsive Neurostimulator, Rhode Island Hospital, Rush University Medical Center: Chicago, Scientific Computing and Imaging Institute: University of Utah Salt Lake City, Second Annual Deep Brain Stimulation (DBS) Think Tank, St. Joseph's Hospital and Medical Center, Stanford University, Stroke, Subcallosal Cingulate, Subthalamic Nucleus, Third Annual Deep Brain Stimulation (DBS) Think Tank, Tourette Syndrome (TS), Transdiagnostic Restoration of Affective Networks by System Identification and Function Oriented Real-Time Modeling in Deep Brain Stimulation, Treatment Resistant Depression, United States, University of Alabama at Birmingham, University of Amsterdam, University of California, University of California San Francisco, University of Florida, University of Kentucky Chandler Medical Center Lexington, University of Queensland Brisbane, University of Utah Salt Lake City, University of Washington (Seattle), USA, VA Greater Los Angeles Healthcare System, Viability of a DBS Industry Roadmap and Consortium
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Alzheimer’s Disease Biomarkers: Updated Hypothetical Model (Lancet Neurology)
Summary A hypothetical model of the major biomarkers of Alzheimer’s Disease, published by the same authors in 2010, has been updated in the light of new evidence. Full Text Link Reference Jack, CR. Jr. Knopman, DS. [and] Jagust, WJ. [et … Continue reading →
Posted in Diagnosis, For Doctors (mostly), For Researchers (mostly), International, Systematic Reviews
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Tagged Aβ, Aβopathy, Aβopathy Acceleration of Antecedent Tauopathy, Alzheimer's Disease: Hypothetical Model(s), Alzheimer’s Disease Biomarkers, Amyloid, Amyloid Beta, Amyloid Beta Protein, Amyloid Proteins, Amyloid-β (Aβ), Apolipoprotein E, Beta-Amyloid, Beta-Amyloid Plaques, Biomarker Assessments in Alzheimer’s Disease, Biomarkers, Biomarkers Predicting Cognitive Decline and Alzheimer's Disease, Brain Beta Amyloid Load, Brain Deposition of Amyloid, Cerebrospinal Fluid, Cerebrospinal Fluid (CSF), Clearance of Amyloid Beta Protein, Cognitive Impairment, Cognitive Response to Progression of Pathophysiology, CSF Aβ, CSF Biomarkers, CSF Tau, Department of Biomedical Statistics and Informatics: Mayo Clinic (Rochester), Department of Neurology: Mayo Clinic (Rochester), Department of Neurosciences: University of California-San Diego, Department of Radiology: Mayo Clinic (Rochester), Early Detection of Alzheimer’s Disease, Early Diagnosis of Alzheimer's Disease, Fluid and Imaging Biomarkers, Indexing Subjects by Time, Inter-Subject Variability, β-amyloid, β-Amyloid 1-42 (Aβ42), Lancet Neurology, Longitudinal Population Studies of Diagnostic Biomarkers, Mayo Clinic: Rochester, Metabolic FDG-PET, Molecular PIB-PET, Neurodegeneration, Neurofibrillary Tangles (NFTs), Neuroimaging, Neuroimaging of Dementia, Neuroimaging Tools, Ordering of Alzheimer's Disease Biomarkers, Pathophysiological Processes in Alzheimer’s Disease, Positron Emission Tomography (PET), Preclinical Alzheimer's Disease, Prodromal Alzheimer's Disease, Proteinopathies, School of Public Health and Helen Wills Neuroscience Institute: University of California, Sequence of Pathological Events in Alzheimer’s Disease, Structural MRI, Tau, Tau Pathology, Tau Protein, Temporal Evolution of Alzheimer’s Disease Biomarkers, Temporal Ordering of Biomarkers, Test to Detect Early-Stage Alzheimer’s Disease, United States, University of California, University of Pathology and Laboratory Medicine and Institute on Aging: University of Pennsylvania, University of Pennsylvania School of Medicine, USA, Veterans Affairs and University of California
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