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Tag Archives: MCI
Mild Cognitive Impairment: Diagnosis and Management (JAMA)
Summary Mild cognitive impairment (MCI), defined as the “pre-dementia stage on the continuum of cognitive decline, characterized by objective impairment in cognition that is not severe enough to require help with usual activities of daily living”, tends to occur in … Continue reading
Posted in Community Care, For Nurses and Therapists (mostly), For Researchers (mostly), International, Non-Pharmacological Treatments, Pharmacological Treatments, Quick Insights, Systematic Reviews, Universal Interest
Tagged Aerobic Exercise, Cognitive Activity, Cognitive Decline, Department of Internal Medicine, Department of Neurology and Stroke Program: University of Michigan, Institute for Healthcare Policy and Innovation: University of Michigan, Institute for Social Research: University of Michigan, Institute of Gerontology: University of Michigan, JAMA, Late-Life Cognitive Decline, MCI, MCI: Mild Cognitive Impairment, Mental Wellbeing, Mild Cognitive Impairment, Mild Cognitive Impairment (MCI), Mild Cognitive Impairment More Prevalent in Men, National Institute on Aging (NIA), Physical Activity, Physical Activity as a Protective Factor for Cognitive Decline and Dementia, Pre-Dementia (MCI), Primary Care, Progression of Mild Cognitive Impairment to Dementia, Rates of Conversion From Mild Cognitive Impairment to Dementia, Risk and Protective Factors for Cognitive Decline and Dementia, Social Engagement, Social Inclusion, United States, University of Michigan, USA, Veterans Affairs Center for Clinical Management Research: Michigan
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Two Sides of the Dementia Case-Finding Debate (BMJ)
Summary The UK government is introducing incentives for general practitioners to check for dementia in patients aged 75 and older, with the intention that timely diagnosis facilitates earlier support for patients with dementia. Critics of this policy allege that this … Continue reading
Posted in Acute Hospitals, Community Care, Diagnosis, For Doctors (mostly), For Nurses and Therapists (mostly), For Researchers (mostly), For Social Workers (mostly), Models of Dementia Care, National, NHS, Patient Care Pathway, Quick Insights, Standards, UK, Universal Interest
Tagged BMJ, British Medical Journal (BMJ), Case Finding for Patients with Dementia, Commissioning for Quality and Innovation (CQUIN) Indicators, Dementia Case Finding, Dementia Case Finding Scheme, Dementia Commissioning for Quality and Innovation (CQUIN), Early Diagnosis, Early Diagnosis of Alzheimer's Disease, Early Screening, Ethical Issues of Dementia Care, Ethics and Decision-Making, General Practice, GPs, Head to Head Debates, Incident Dementia, Mandate to the NHS Commissioning Board, MCI, MCI: Mild Cognitive Impairment, Mental Health Care, National Dementia CQUIN, National Screening Committee, NHS Mandate, Prime Minister's Challenge on Dementia, Screening, Screening for Dementia, Timely Diagnosis, UK National Screening Committee
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Alzheimer’s Disease-Related Gray Matter Atrophy Prevention Using B-Vitamin Treatment (NHS Choices / PNAS)
Summary Researchers explored the prevention of brain atrophy in areas related to cognitive decline and Alzheimer’s disease (AD) by lowering elevated plasma homocysteine using B vitamins. An earlier study on people with increased dementia risk had indicated that high-dose B-vitamin … Continue reading
Posted in For Researchers (mostly), In the News, International, NHS Digital (Previously NHS Choices), Nutrition, Pharmacological Treatments, Quick Insights, UK, Universal Interest
Tagged Alzheimer's Disease, Atrophy and Cognition, B vitamins (Folate B6 and B12), B-Vitamin Supplementation, B-Vitamin Treatments, Behind the Headlines, Brain Atrophy, Critical Appraisals, Diet and Alzheimer's Brain Changes, Dietary Choices, Folic Acid, Functional Magnetic Resonance Imaging of the Brain (FMRIB) Centre: University of Oxford, Gray Matter Atrophy, Homocysteine, John Radcliffe Hospital: Oxford, Magnetic Resonance Imaging (MRI), MCI, Medial Temporal Lobe, Mild Cognitive Impairment (MCI), MRI, MRI Brain Imaging, MRI Scans, Neuropsychological Tests, Nuffield Department of Clinical Neurosciences: University of Oxford, Plasma Homocysteine, PNAS, Proceedings of the National Academy of Sciences of the United States of America (PNAS), Regional Brain Atrophy, University of Oxford, Vitamin B Slows the Progression of Alzheimer’s Disease, Vitamin B12, Vitamin B6
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Systematic Review of Treatments to Prevent Cognitive Decline (CMAJ: Journal of the Canadian Medical Association)
Summary This systematic review examined the best 32 randomised controlled trials (RCTs) investigating treatments for cognitive decline, including drug treatments, hormone therapies, nutritional supplements, physical activity and cognitive exercises. The authors looked comprehensively at pharmacological treatments and non-pharmacological treatments in healthy … Continue reading
Posted in For Carers (mostly), For Doctors (mostly), For Nurses and Therapists (mostly), For Researchers (mostly), In the News, International, NHS Digital (Previously NHS Choices), Non-Pharmacological Treatments, Pharmacological Treatments, Quick Insights, Systematic Reviews
Tagged Behind the Headlines, Brain Training, Canada, Canadian Medical Association Journal, Cholinesterase Inhibitors, CMAJ: Canadian Medical Association Journal, Cognitive Activity and Cognitive Decline, Cognitive Decline, Cognitive Decline Studies, Cognitive Exercises, Cognitive Impairment, Cognitive Stimulation Therapy, Cognitive Training, Cognitive Training Exercises, DHEA (Synthetic Version of Hormone Produced by Adrenal Glands), Divisions of Geriatric Medicine and General Internal Medicine: University of Toronto, Estrogens, Exercise, Exercise for Cognitive Impairment, Exercise Regimens, Fatty Acids, Fish Oil, Fish-Oil Supplements, Ginkgo Biloba Extract, Hormonal Therapies, Hormone Therapy (HT), Journal de l'Association Medicale Canadienne, MCI, MCI: Mild Cognitive Impairment, Mild Cognitive Impairment, Mild Cognitive Impairment (MCI), Moderate Exercise, NMDA (N-Methyl-D-Aspartate), Nutritional Supplements, Oestrogens, Omega-3 Fatty Acids, Omega-3 PUFA Supplementation (Dietary), Oral Nutritional Supplements, Oral Nutritional Supplements (ONS), Polyunsaturated Fatty Acids (PUFA), Prevention, Prophylaxis, PUFA: Polyunsaturated Fatty Acids, Sudoku, Testosterone, University of Toronto, Vitamin Pills
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Exploring the Potential of Deep Brain Stimulation (TED Talk by Neurosurgeon Andres Lozano)
Summary Neurosurgeon Andres Lozano discusses recent developments in the potential uses of deep brain stimulation (DBS) for the alleviation of symptoms across many different neurological / neuropsychological conditions, including Parkinson’s Disease, dystonia, depression and other mental illnesses, and possibly even … Continue reading
Posted in Depression, International, Mental Health, Non-Pharmacological Treatments, Parkinson's Disease, Quick Insights, Universal Interest
Tagged Alzheimer's Disease, Andres Lozano (Neurosurgeon), Brain Imaging, Deep Brain Stimulation (DBS), Deep Brain Stimulation for the Treatment of Alzheimer Disease, Deep Brain Stimulation for the Treatment of Dementia, Dystonia, Fornix, Lewy Body Society, Magnetic Resonance Imaging (MRI), MCI, MCI: Mild Cognitive Impairment, Mild Cognitive Impairment (MCI), MRI, MRI Scans, Neurodegeneration, Neurodegenerative Diseases, Neuroimaging, Neuroimaging of Dementia, Neurological Disease, Neurology, Neuropsychology, Nucleus Basalis of Meynert, Pre-Dementia (MCI), TED Conference, TED Talks, TEDTalks, TEDxCaltech, Toronto, Toronto Western Hospital, Treatment of Alzheimer's Disease, University of Toronto, YouTube
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Neuroimaging for Early Diagnosis of Neurodegenerative Disease
Summary The roles of magnetic resonance and radionuclide imaging in the early diagnosis and pre-clinical detection of dementia and parkinsonism are reviewed. Structural imaging has traditionally been used to exclude alternate diagnoses, but recent advances in magnetic resonance and multimodal … Continue reading
Posted in Diagnosis, For Doctors (mostly), For Researchers (mostly), Parkinson's Disease
Tagged 123I-FP-CIT (Dopamine Transporter) Single Photon Emission Computed Tomography Neuroimaging, Alzheimer's Disease, Canada, DAT SPECT, Dopamine Transporter (DAT) Ligand, Early Detection of Preclinical Disease, Early Diagnosis, Early Differential Diagnosis, FDG-PET Imaging, Fluorodeoxyglucose (FDG) PET, fMRI, Functional Brain Imaging, Functional Magnetic Resonance Imaging (fMRI), Magnetic Resonance Imaging (MRI), Magnetic Resonance Imaging (MRI) Scan, MCI, MCI: Mild Cognitive Impairment, Mild Cognitive Impairment (MCI), MRI, MRI Brain Imaging, Multimodal Imaging, Neurodegenerative Diseases, Neuroimaging, Neuroimaging of Dementia, Neuroimaging Tools, Pacific Parkinson's Research Centre, Parkinsonism, Pathology and Imaging Studies, Scans Without Evidence of Dopamine Deficiency (SWEDD), Single Photon Emission Computed Tomography (SPECT), University of British Columbia and Vancouver Coastal Health, Volumetric Analysis of Regional Tissue Loss
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Pre-Dementia More Common in Men than Women (BBC Health News)
[A version of this item appears in: Dementia: the Latest Evidence Newsletter (RWHT), Volume 2 Issue 7, February 2012]. Summary Men show a higher risk of developing the earliest signs of dementia, namely mild cognitive impairment (MCI), whereas women are more likely to … Continue reading
Posted in BBC News, For Researchers (mostly), In the News, International, Quick Insights, Universal Interest
Tagged Mayo Clinic, Mayo Clinic Alzheimer’s Disease Research Center, Mayo Clinic Study of Aging, MCI, MCI: Mild Cognitive Impairment, Men vs. Women (Diseease Prevalence), Mild Cognitive Impairment (MCI), National Institute on Aging (US), Olmsted County: Minnesota, Pre-Dementia (MCI), Robert Wood Johnson Foundation, US National Institute on Aging
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