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Tag Archives: Medication-Related Risks
Pharmacological Treatment of Agitation in Persons With Dementia (British Journal of Clinical Pharmacology)
Summary A systematic review and meta‐analysis of pharmaceutical treatments for alleviating agitation in dementia has been performed. Regarding the efficacy and treatment acceptability of these medications, it is reported that: “Risperidone, SSRIs as a class and Dextromethorphan / Quinidine demonstrated … Continue reading →
Posted in Antipsychotics, For Doctors (mostly), For Nurses and Therapists (mostly), For Researchers (mostly), International, Mental Health, Pharmacological Treatments, Quick Insights, Systematic Reviews
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Tagged Agitation, Agitation and Aggression, Antidepressants, Antidepressants for Agitation and Psychosis in Dementia, Antipsychotics in Elderly People with Dementia, Asian Centre for Evidence Synthesis in Population Implementation and Clinical Outcomes (PICO): Monash University Malaysia, Atypical Antipsychotics, Australia, Behavioural and Psychological Symptoms of Dementia (BPSD), Behavioural Problems, Behavioural Problems in People With Dementia, BPSD: Behavioral and Psychological Symptoms of Dementia, British Journal of Clinical Pharmacology, Center of Pharmaceutical Outcomes Research (CPOR): Naresuan University, Centre for Medicine Use and Safety: Monash University, Chulalongkorn University (Bangkok), Dementia-Related Agitation, Department of Clinical Pharmacy: Mahasarakham University, Department of Pharmacy Practice: Naresuan University, Department of Psychiatry: King Chulalongkorn Memorial Hospital, Dextromethorphan / Quinidine (DM/Q: Nuedexta™), Faculty of Medicine: Chulalongkorn University, Faculty of Pharmaceutical Sciences: Naresuan University, Faculty of Pharmacy and Pharmaceutical Sciences: Monash University, Haloperidol, Health and Well-being Cluster - Global Asia in the 21st Century (GA21) Platform: Monash University Malaysia, Interventions for BPSD, King Chulalongkorn Memorial Hospital, Kolling Institute of Medical Research: Royal North Shore Hospital, Mahasarakham University (Thailand), Malaysia, Managing Agitation, Medication-Related Risks, Medications: Best Usage, Medicines Optimisation, Monash University, Monash University Malaysia, Mood Disturbances, Naresuan University (Thailand), Neuroleptics, Neuropsychiatric Symptoms (NPS), Neuropsychiatric Symptoms in People With Dementia, Oxcarbazepine, Patient Safety, Potentially Inappropriate Medications (PIM), Potentially Inappropriate Prescribing (PIP), Potentially Inappropriate Prescribing in Advanced Dementia, Prescribing of Antipsychotic Drugs For People With Dementia, Psychotropic Drugs, Psychotropic Medication, Psychotropic Prescribing, Reducing Agitation and Distress, Risperidone, Royal North Shore Hospital (Australia), School of Pharmacy: Monash University Malaysia, Selective Serotonin Reuptake Inhibitors (SSRIs), SSRIs: Selective Serotonin Reuptake Inhibitors, Systematic Reviews and Meta-Analyses, Thailand, University of Sydney
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Review of Non-Pharmacological Interventions for Dementia-Related Agitation: Including a Brief Analysis of the Risks and Benefits of Drug Treatments (Translational Psychiatry)
Summary A recently published literature review evaluates the best available evidence on the effectiveness of various non-pharmacological interventions for reducing dementia-related agitation. The author also briefly addresses current viewpoints on balancing the risks and benefits of pharmacotherapy in the management … Continue reading →
Posted in Acute Hospitals, Antipsychotics, For Carers (mostly), For Doctors (mostly), For Nurses and Therapists (mostly), For Researchers (mostly), Local Interest, Management of Condition, Mental Health, Models of Dementia Care, New Cross Hospital, Non-Pharmacological Treatments, Person-Centred Care, Personalisation, Pharmacological Treatments, Quick Insights, Royal Wolverhampton NHS Trust, Royal Wolverhampton NHS Trust Authorial Affiliation, Systematic Reviews, UK, Universal Interest, Wolverhampton
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Tagged ACADIA Pharmaceuticals, Agitation, Agitation and Aggression, Alternatives to Antipsychotic Drugs, Animal Assisted Therapy, Antipsychotics, Antipsychotics and Risk of Venous Thromboembolism, Antipsychotics in Elderly People with Dementia, Antipsychotics Limitation in Dementia, Antipsychotics-Related Mortality Risks, Aromatherapy, Arts and Music in Dementia, Atypical Antipsychotics, Avanir Pharmaceuticals Inc (California), Behavioural Alternatives to Antipsychotic Drugs, Behavioural and Psychological Symptoms of Dementia (BPSD), Behavioural Problems, Behavioural Problems in People With Dementia, Behavioural Variant Frontotemporal Dementia (bvFTD), BPSD, BPSD: Behavioral and Psychological Symptoms of Dementia, Carbamazepine, Citalopram, Citalopram for Agitation in Alzheimer's Disease: CitAD Trial, Cognitive Behavioral Therapy, Dementia-Related Agitation, Department of Medicine: Royal Wolverhampton NHS Trust, Describe Investigate Create and Evaluate (DICE) Approach, East Kent Hospitals University NHS Foundation Trust, Electroconvulsive Therapy for Agitation and Aggression in Dementia, Improving the Quality of Life for People With Dementia, Interventions for BPSD, Intra-Cellular Therapies, Medication-Related Risks, Medications: Best Usage, Medicines Optimisation, Memantine, Mirtazapine, Mood Disturbances, Multisensory Stimulation, Music Therapy, Music Therapy for BPSD, Music-Based Therapeutic Interventions, Nature Publishing Group, Neuroleptic Discontinuation, Neuroleptics, Neuropsychiatric Symptoms (NPS), Neuropsychiatric Symptoms in People With Dementia, Non-Pharmacological Management of Symptoms, Non-Pharmacological Treatments, Otsuka Pharmaceuticals Limited, Pharmacological Treatments, Potential Harms of Antipsychotic Use, Potentially Inappropriate Medications (PIM), Potentially Inappropriate Prescribing (PIP), Potentially Inappropriate Prescribing in Advanced Dementia, Prescribing of Antipsychotic Drugs For People With Dementia, Quetiapine, Reducing Inappropriate Use of Antipsychotics in Dementia, Risperidone, Simulated Presence Therapy (SPT), Simulated Presence Therapy for BPSD, Targeted Interdisciplinary Model for Evaluation and Treatment of Neuropsychiatric Symptoms (TIME), Translational Psychiatry, Withdrawal of Neuroleptic Medications
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MATCH-D: Medication Appropriateness Tool for Comorbid Health Conditions in Dementia (Internal Medicine Journal / BMJ Open)
Summary The Medication Appropriateness Tool for Comorbid Health conditions in Dementia (MATCH-D) criteria were developed to provide consensus guidance on the use of medications for people with dementia. Full Text Link Reference Page, AT. Potter, K. Clifford, RM. [et al] … Continue reading →
Posted in Acute Hospitals, Antipsychotics, Commissioning, Community Care, For Doctors (mostly), For Nurses and Therapists (mostly), For Researchers (mostly), Integrated Care, International, Management of Condition, Models of Dementia Care, Person-Centred Care, Pharmacological Treatments, Quick Insights, Universal Interest
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Tagged Australia, BMJ Open, BMJ Publishing Group Ltd, Brighton and Sussex Medical School: University of Sussex, Centre for Education and Research on Ageing: University of Sydney, Comorbid Health Conditions in Dementia, Comorbidity, Comorbidity and Dementia, Complex Comorbidities, Concord Hospital (Sydney Australia), Dementia and Comorbidity, Dementia Comorbidities, Deprescribing, Drug-Drug Interactions, Faculty of Pharmacy: University of Sydney, Healthcare Provision for People With Dementia and Comorbidity, Inappropriate Prescribing, Internal Medicine Journal, Ireland, Managing Comorbidity and Complexity, MATCH-D: Medication Appropriateness Tool for Comorbid Health conditions in Dementia, Medication Appropriateness Tool for Comorbid Health conditions in Dementia (MATCH-D), Medication Management, Medication-Related Risks, Medications: Best Usage, Medicines Optimisation, Multiple Comorbidities, Multiple Medications (Polypharmacy), New South Wales (Australia), Optimising Medications for Older People With Multiple Comorbidities, Optimising Prescribing and Deprescribing in Older Adults With Dementia, Over-Medication, Potentially Inappropriate Prescribing, Potentially Inappropriate Prescribing in Advanced Dementia, Royal College of Surgeons in Ireland, School of Allied Health: University of Western Australia, School of Medicine: University of Western Australia, School of Pharmacy: Royal College of Surgeons in Ireland, University of Sussex, University of Sydney, University of Western Australia, Western Australian Centre for Health and Ageing: University of Western Australia
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Common Medicines Associated With Dementia Risk (BBC News / JAMA Internal Medicine)
Summary A US study, published in JAMA Internal Medicine, concerning long-term use of anticholinergic-type drugs (those which block the neurotransmitter acetylcholine), in older people, has discovered an association with the risk of developing dementia. Higher doses and prolonged use of … Continue reading →
Posted in BBC News, For Carers (mostly), For Doctors (mostly), For Nurses and Therapists (mostly), For Researchers (mostly), In the News, International, NHS Digital (Previously NHS Choices), Pharmacological Treatments, Practical Advice, Quick Insights, Statistics, Universal Interest
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Tagged Acetylcholine, Anticholinergic Drugs, Anticholinergics, Bazian, BBC Health News, Behind the Headlines, Benadryl, Branta Foundation, Chlorpheniramine Maleate, Cumulative Anticholinergic Use (Dementia Risk Factor), Dementia Risk Factors, Dementia Risk Reduction, Department of Biostatistics and Epidemiology: Perelman School of Medicine, Department of Biostatistics: University of Washington, Department of Epidemiology: University of Washington, Diphenhydramine (Sleep Aid), Ditropan (Incontinence Drug), Division of General Internal Medicine: University of Washington, Division of Geriatric Medicine: University of Pittsburgh, Doxepin (Antidepressant), Doxepin Hydrochloride, Drug Side-Effects, Epidemiology, Epidemiology and Statistics, Group Health Research Institute: Seattle, Hay-Fever Treatments, JAMA Internal Medicine, Meclizine Hydrochloride, Medication-Related Risks, Modifiable Risk Factors, National Institute on Aging (NIA), National Institutes of Health (NIH), National Institutes of Health (US), Nytol, Olanzapine, Oxybutynin (Urinary Incontinence Drug), Perelman School of Medicine: University of Pennsylvania, Piriton (Antihistamine), Risk Factors, Risk Factors for Alzheimer's Diseease, School of Pharmacy: University of Washington, Seroxat (Antidepressant), Sleep Aids, Strong Anticholinergics Association With Incident Dementia, Total Standardised Daily Doses (TSDDs): Cumulative Exposure, United States, University of Pittsburgh, University of Washington, USA, Xybutynin Chloride
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