Tag Archives: Microglia

Flashing Light: A Potential Alternative to Drug Treatment to Prevent Amyloid Plaque Formation? (BBC News / Nature)

Posted on December 12, 2016 by Dementia and Elderly Care News

Summary Animal research on genetically modified mice suggests that a specialised form of flashing light therapy might help slow the progression of Alzheimer’s Disease. It appears that shining a strobe light, flashing at a rate of 40Hz, into rodents’ eyes … Continue reading →

Possibly a Paradigm Shift in the Understanding of Parkinson’s Disease? (BBC News / Cell / NHS Choices)

Posted on December 5, 2016 by Dementia and Elderly Care News

Summary Animal research in the United States and Sweden suggests that Parkinson’s Disease may be caused by bacteria living in the gut. It appears likely that the certain gut bacteria (the “gut microbiome”) could be responsible for releasing chemicals (SCFAs) … Continue reading →

Posted in Animal Studies, BBC News, For Doctors (mostly), For Nurses and Therapists (mostly), For Researchers (mostly), In the News, International, NHS Digital (Previously NHS Choices), Parkinson's Disease, Quick Insights, Universal Interest | Tagged Abnormal Proteins (Alpha-Synuclein), Alpha-Synucleinopathies, Arizona State University, BBC Health News, Behind the Headlines, Biodesign Institute: Arizona State University, Biology and Biological Engineering Department: Chalmers University of Technology, California Institute of Technology, Cell (Journal), Chalmers University of Technology (Gothenburg), Chalmers University of Technology (Sweden), David Geffen School of Medicine at UCLA, Department of Computer Science and Engineering: University of California, Department of Internal Medicine: Rush University Medical Center, Department of Neurological Sciences: Rush University Medical Center, Department of Neurology: The David Geffen School of Medicine at UCLA, Department of Pediatrics: University of California, Division of Biology and Biological Engineering: California Institute of Technology, Division of Gastroenterology: Rush University Medical Center, Early Parkinson Disease, Genetically Engineered Mice, Gut Bacteria, Gut Microbes, Gut Microbiome, Gut Microbiota, Human Gut Microbiome: a Potential Risk Factor for Parkinson's Disease, Immune Cells (Microglia), Inflammation, Inflammation and Neurodegenerative Diseases, Intestinal Microbiota, α-Syn-Overexpressing Mice, α-Synuclein, α-Synuclein Aggregation, Knut and Alice Wallenberg Foundation, Mice, Microbiota Transplants, Microglia, Motor Deficits, Neuroinflammation, Parkinson’s Disease Pathogenesis, Risk Factors, Risk Factors for Parkinson's Disease, Rush University Medical Center, Rush University Medical Center: Chicago, Section of Movement Disorders: Rush University Medical Center, Short-Chain Fatty Acids (SFCAs), Sweden, Swedish Research Council, Swette Center for Environmental Biotechnology: Biodesign Institute, Synucleinopathies, United States, University of California, USA | Leave a comment

More on Inflammation, the Immune System and Neurodegenerative Diseases (NHS Choices / Frontiers in Neuroscience / BBC News)

Posted on June 19, 2016 by Dementia and Elderly Care News

Summary A review article was published last month, covering evidence suggesting that the body’s innate immune system may be involved in neurodegenerative conditions, including Alzheimer’s Disease and Parkinson’s Disease, associated with a cascade of progressive damage to brain cells. Further … Continue reading →

Targeting Brain Inflammation May Help Protect Against Alzheimer’s Disease? (BBC News / MRC / NHS Choices / Brain)

Posted on January 10, 2016 by Dementia and Elderly Care News

Summary Animal research at the University of Southampton, funded by the Medical Research Council (MRC) and Alzheimer’s Research UK indicates that blocking a receptor (CSF1R), which is responsible for regulating the production of new immune cells (microglia) in the brain, … Continue reading →

Posted in Alzheimer’s Research UK, Animal Studies, BBC News, For Doctors (mostly), For Researchers (mostly), In the News, NHS Digital (Previously NHS Choices), Quick Insights, UK | Tagged APP/PS1 Transgenic Mouse Model, BBC Health News, Behind the Headlines, Brain and Immune System, Brain Inflammation, Brain: a Journal of Neurology, Centre for Biological Sciences: University of Southampton, Colony-Stimulating Factor 1 Receptor (CSF1R), CSF1R Inhibition in Models of Alzheimer's Disease, CSF1R Receptor, CSF1R-Dependent Pro-Mitogenic Cascade, CSF1R-Inhibition Strategies, Dementia Consortium, Division of Biomedical and Life Sciences: Lancaster University, Faculty of Health and Medicine: Lancaster University, Genetically Engineered Mice, GW2580, Immune Suppression, Immune System, Improved Performance in Memory and Behavioural Tasks, Inflammation, Institute for Life Sciences: University of Southampton, Lancaster, Lancaster University, Medical Research Council (MRC), Mice, Microglia, Microglial Multiplication, Microglial Proliferation, Modification of CSF1R Activation to Reduce Microglial Activation, Mouse Model of Alzheimer's Disease, MRC New Investigator Research Grant (NIRG), MRC: Medical Research Council, Neurodegeneration, Neurodegenerative Disease Research, Neurodegenerative Disorders, Neuroimmunology, Neuroinflammation, Novel Targets in Neurodegeneration, Pharmacological Targeting of CSF1R, Prevention of Synaptic Degeneration, Southampton, Transgenic Mice, Tyrosine Kinase Inhibitor (GW2580), University of Southampton | Leave a comment

Drug Alteration to Brain’s Immune System Prevents Mice Developing Alzheimer’s Dementia? (BBC News / Journal of Neuroscience)

Posted on April 17, 2015 by Dementia and Elderly Care News

Summary Latest research evidence, from Duke University in the US, suggests that the immune system plays a part in the development of Alzheimer’s Disease (in mice). It appears that immune cells which attack nutrients in the brain may be an … Continue reading →

Posted in Animal Studies, BBC News, For Doctors (mostly), For Nurses and Therapists (mostly), For Researchers (mostly), In the News, International, Quick Insights, Universal Interest | Tagged Alzheimer's Disease, Amino Acid Deprivation, Arginase, Arginine, Arginine Catabolism, Arginine Deprivation, BBC Health News, Causes of Alzheimer's Disease, CVN-AD Mouse Model of Alzheimer’s Disease, Department of Immunology: Duke University Medical Center, Department of Laboratory Medicine: University of Washington, Department of Medicine: Duke University Medical Center, Department of Neurobiology and Anatomy: West Virginia University School of Medicine, Department of Neurology: Duke University Medical Center, Duke University, Duke University Medical Center, Duke University Medical Center (North Carolina), Extracellular Arginase, Immune Suppression, Immune System, Immunohistochemistry, Immunology, Immunosuppressive CD11c+ Microglia, Inflammation, Inhibition of Arginase, Journal of Neuroscience, Local Immune Suppression, Local Immune-Mediated Amino Acid Catabolism, Mice, Microglia, Mouse Model of Alzheimer's Disease, Neuroinflammation, Ornithine Decarboxylase, Potential Cause for Alzheimer’s Disease: Arginine Deprivation, Proinflammatory Factors, United States, University of Washington, USA, West Virginia University School of Medicine | Leave a comment

Tag Archives: Microglia

Flashing Light: A Potential Alternative to Drug Treatment to Prevent Amyloid Plaque Formation? (BBC News / Nature)

Possibly a Paradigm Shift in the Understanding of Parkinson’s Disease? (BBC News / Cell / NHS Choices)

More on Inflammation, the Immune System and Neurodegenerative Diseases (NHS Choices / Frontiers in Neuroscience / BBC News)

Targeting Brain Inflammation May Help Protect Against Alzheimer’s Disease? (BBC News / MRC / NHS Choices / Brain)

Drug Alteration to Brain’s Immune System Prevents Mice Developing Alzheimer’s Dementia? (BBC News / Journal of Neuroscience)

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