Tag Archives: Mild Alzheimer’s Disease

Another Recent Alzheimer’s Disease Drug Trial Disappointment (Lancet)

Summary Researchers aimed to discover whether LMTM [Leuco-methylthioninium bis(hydromethanesulfonate] might be safe and effective for slowing disease progression in patients with mild to moderate Alzheimer’s Disease. LMTM had previously been found to work as a selective inhibitor of tau protein … Continue reading

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Alzheimer’s Disease: Solanezumab Drug Trial Flops (BBC News / Alzheimer’s and Dementia)

Summary The phase 3 EXPEDITION3 trial has been abandoned, as Solanezumab failed to slow cognitive decline in tests on around 2,000 patients with Alzheimer’s Disease. Several other amyloid-clearance drugs are going through trials apparently. Full Text Link Reference Walsh, F. … Continue reading

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Use of NICE Appraised Medicines in the NHS in England (HSCIC)

Summary The Health and Social Care Information Centre (HSCIC) estimates that national figures for Alzheimer’s Disease medicine use have been underestimated by around five per cent. Section 3.1 in this report relates to Alzheimer’s Disease medicines: donepezil, galantamine, rivastigmine and memantine. … Continue reading

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