Tag Archives: Mild Cognitive Impairment

Risk of Cognitive Impairment in Diabetes Patients Associated with Metformin (Diabetes Care)

Summary Metformin use is associated with impaired cognitive performance. Vitamin B12 and calcium supplements may alleviate metformin-induced vitamin B12 deficiency, and might improve cognitive outcomes. Full Text Link (Note: This article requires a suitable Athens password, a journal subscription or … Continue reading

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Cognitive and Neuroimaging Predictors of Progression from Mild Cognitive Impairment to Dementia (NHS Choices / Journal of Alzheimer’s Disease)

Summary The detection of pre-clinical Alzheimer’s Disease appears to be accomplished best by the use of a combination of information, taken from targeted neuroimaging and complementary neuropsychological assessments of cognitive functioning. This combination of approaches may be necessary in order to … Continue reading

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Rates of Conversion From Mild Cognitive Impairment to Alzheimer’s Dementia (Dementia and Geriatric Cognitive Disorders Extra)

Summary This systematic review examines and summarises published estimates for the rate(s) of conversion from mild cognitive impairment or amnestic mild cognitive impairment to Alzheimer’s Disease / dementia. Wide variations in conversion rates are observed. Full Text Link Reference Ward, … Continue reading

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Recent Systematic Reviews and Meta-Analyses on Non-Pharmacological Treatments

Some of the following articles are available freely, while the full-text of the other articles may need a suitable Athens password, a journal subscription or payment for access. The Bibliographic Citations Defina, P.A. Moser, R.S. Glenn, M. [et al]. (2013). … Continue reading

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NICE Eyes on Evidence: Cumulative Index 2013 (NICE Evidence)

Summary The NICE Evidence‘s Eyes on Evidence service covers significant new evidence across a range of topics. Here is an alphabetical list of the items, which have appeared so far this year, of broad interest to readers of this information … Continue reading

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Centrally Acting ACE Inhibitors Reduce Rate of Cognitive Decline in Dementia? (BMJ Open)

Summary It has been found that taking angiotensin-converting enzyme (ACE) inhibitors, a class of drugs which help to reduce blood pressure by relaxing the walls of blood vessels, may help to slow mental decline in people diagnosed with dementia. The … Continue reading

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Systematic Review of Treatments to Prevent Cognitive Decline (CMAJ: Journal of the Canadian Medical Association)

Summary This systematic review examined the best 32 randomised controlled trials (RCTs) investigating treatments for cognitive decline, including drug treatments, hormone therapies, nutritional supplements, physical activity and cognitive exercises. The authors looked comprehensively at pharmacological treatments and non-pharmacological treatments in healthy … Continue reading

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Vitamin E for Alzheimer’s Dementia and Mild Cognitive Impairment (Cochrane Database)

Summary This systematic review assessed the efficacy of Vitamin E in the treatment of Alzheimer’s dementia (AD) and for the prevention of progression of mild cognitive impairment (MCI) to dementia. The authors found no evidence for Vitamin E being of … Continue reading

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Prevalence: 25% People with Parkinson’s Disease Without Dementia Have Mild Cognitive Impairment

[This abstract first appeared in: Dementia: the Latest Evidence Newsletter RWHT Volume 1 Issue 7 February 2011]. Abstract This international study investigated the frequency of mild cognitive impairment (MCI) in people with Parkinson’s disease (PD) without dementia. Although different tests of cognitive assessment … Continue reading

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