Tag Archives: Misfolded Proteins

Potential Risk of Alzheimer’s Disease Transmission (BBC News / NHS Choices / Nature / MRC)

Summary There may be a theoretical risk of Alzheimer’s Disease being transmissible during surgical procedures, in the manner of Creutzfeldt-Jakob disease (CJD). This hypothesis has arisen as a result of the examination of the brains of eight patients who had … Continue reading

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New Hopes for Disease-Modifying Pharmacological Dementia Treatment (BBC News / AAIC / ARUK)

Summary Trials of the drug Solanezumab were abandoned in apparent failure in 2012. More detailed examination of the data has since revealed evidence that this medication may have a role in slowing the pace of progression in Alzheimer’s Disease slightly, … Continue reading

Posted in Alzheimer’s Research UK, BBC News, Charitable Bodies, Diagnosis, For Doctors (mostly), For Nurses and Therapists (mostly), For Researchers (mostly), In the News, International, Management of Condition, Models of Dementia Care, Patient Care Pathway, Pharmacological Treatments, Quick Insights, Statistics, UK, Universal Interest | Tagged , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , | Leave a comment

Evolutionary Mutation of Human Prion Protein May Prevent Prion Diseases? (NHS Choices / BBC News / Nature)

Summary A natural human mutation (called V127) in the gene encoding prion protein may offer resistance to CJD. A study using mice with this genetic mutation appears to confirm resistance to prion diseases. This finding may in future help in … Continue reading

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Early Diagnosis of Alzheimer’s Disease Using Spinal Fluid? (NHS Choices / Cell Reports)

Summary A recent diagnostic study has investigated the possibility of diagnosing Alzheimer’s Disease, years before disease onset, using cerebrospinal fluid (CSF). The technique for identifying people with Alzheimer’s Disease would be based on detecting very small amounts of abnormal (misfolded) … Continue reading

Posted in Diagnosis, For Doctors (mostly), For Researchers (mostly), In the News, International, NHS Digital (Previously NHS Choices), Quick Insights, Universal Interest | Tagged , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , | Leave a comment

Giant Steps: Re-Tracing the Development of a Promising Research Approach

Summary Following the announcement earlier this week of a probable (if still early-stage) historic breakthrough in finding a potential approach to preventing neurodegeneration across Alzheimer’s, Parkinson’s and Huntington’s Diseases, readers may be interested in viewing the publication history of research … Continue reading

Posted in For Doctors (mostly), For Researchers (mostly), In the News, International, NIHR, Parkinson's Disease, Quick Insights, UK | Tagged , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , | Leave a comment

Breakthrough Discovery of Chemical to Prevent Neurodegeneration Across Alzheimer’s, Parkinson’s and Huntington’s Diseases (BBC News / NHS Choices / Science Translational Medicine)

Summary A chemical substance has been identified which shows signs of being able to halt a range of neurodegenerative diseases in mice. This may well be a historic event in research, although more research is required; the development of drug treatments … Continue reading

Posted in Animal Studies, BBC News, For Carers (mostly), For Doctors (mostly), For Researchers (mostly), In the News, NHS Digital (Previously NHS Choices), Parkinson's Disease, Quick Insights, UK, Universal Interest | Tagged , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , | Leave a comment