Tag Archives: Mouse Model of Alzheimer’s Disease

Vitamin D May Not Offer Protection Against Neurological Diseases? (NHS Choices / Nutritional Neuroscience / BJPsych Open)

Summary A recent systematic review of studies into the role of Vitamin D exposure levels / deficiency or supplementation in four neurodegenerative diseases (Alzheimer’s Disease, Motor Neurone Disease, Multiple Sclerosis (MS) and Parkinson’s Disease) found little conclusive evidence for any … Continue reading

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Memories Lost in Alzheimer’s Disease: Potentially Retrievable? (NHS Choices / Nature)

Summary Research on transgenic mice suggests that memories are not destroyed irretrievably by Alzheimer’s Disease; there appears to be problems recalling these lost memories. Lost memories may be retrievable, under experimental conditions, by exposing “Engram Cells” with bright blue light … Continue reading

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Targeting Brain Inflammation May Help Protect Against Alzheimer’s Disease? (BBC News / MRC / NHS Choices / Brain)

Summary Animal research at the University of Southampton, funded by the Medical Research Council (MRC) and Alzheimer’s Research UK indicates that blocking a receptor (CSF1R), which is responsible for regulating the production of new immune cells (microglia) in the brain, … Continue reading

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Novel Approach to Prevention of Alzheimer’s Disease Explored in Laboratory (Express / PloS One)

Summary Researchers at the University of California, San Diego, have explored a different approach to mainstream research into the prevention of Alzheimer’s Disease. It is believed that Alzheimer’s Disease develops when amyloid precursor protein (APP) gets cut-up by enzymes and … Continue reading

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Drug Alteration to Brain’s Immune System Prevents Mice Developing Alzheimer’s Dementia? (BBC News / Journal of Neuroscience)

Summary Latest research evidence, from Duke University in the US, suggests that the immune system plays a part in the development of Alzheimer’s Disease (in mice). It appears that immune cells which attack nutrients in the brain may be an … Continue reading

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Use of Anti-Depressants to Slow Alzheimer’s Disease Onset? (BBC News / Science Translational Medicine / PNAS)

Summary Recent research into transgenic mice (and early, small-scale investigations with people) suggests that the anti-depressant citalopram could be used to slow the onset of Alzheimer’s Disease. This work in the United States appears to show that citalopram may counteract … Continue reading

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Future Dementia Diagnosis or Prediction Via Eye Examinations? (BBC News / US Society for Neuroscience Conference)

Summary The retina is a direct extension of the brain. Early research has discovered that mice genetically engineered to have a version of Alzheimer’s Disease show a corresponding loss thickness in a layer of specific cells in the retina, and … Continue reading

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