Tag Archives: National Institutes of Health (NIH)

Optimism Linked to Longevity (BBC News / PNAS / Bazian)

Posted on August 27, 2019 by Dementia and Elderly Care News

Summary Researchers in the United States, using data from the Nurses’ Health Study and the Veterans’ Health Study, have confirmed that optimists tend to live longer and are more likely to achieve “exceptional longevity” i.e. live to an age of … Continue reading →

Posted in BBC News, For Carers (mostly), For Doctors (mostly), For Nurses and Therapists (mostly), For Researchers (mostly), In the News, International, NHS Digital (Previously NHS Choices), Quick Insights, Statistics, Universal Interest | Tagged Bazian, BBC Health News, BBC UGC Hub, Behavioural Risk Factors, Behind the Headlines, Boston University School of Medicine, Boston University School of Public Health, Brigham and Women's Hospital, Channing Division of Network Medicine: Brigham and Women’s Hospital, Critical Appraisals, Department of Epidemiology: Boston University School of Public Health, Department of Epidemiology: Harvard T.H. Chan School of Public Health, Department of Population Medicine: Harvard Medical School, Department of Psychiatry: Boston University School of Medicine, Department of Social and Behavioral Sciences: Harvard T.H. Chan School of Public Health, Epidemiology, Epidemiology and Statistics, Exceptional Longevity, Fonds de Recherche en Santé–Quebec, Harvard Medical School, Harvard Pilgrim Health Care Institute, Harvard T.H. Chan School of Public Health, Human Longevity, Lee Kum Sheung Center for Health and Happiness: Harvard T.H. Chan School of Public Health, Life Orientation Test – Revised, Lifestyle Risk Factors, Longevity, Massachusetts Veterans Epidemiology Research and Information Center: Veterans Affairs Boston Healthcare System, Mental and Physical Health, Modifiable Risk Factors, National Center for Posttraumatic Stress Disorder: Veterans Affairs Boston Healthcare System, National Institutes of Health, National Institutes of Health (NIH), National Institutes of Health: Clinical Science Research and Development Service, Nurses’ Health Study, Nurses’ Health Study (NHS), Optimism, Optimism Associated With Longevity, Optimists, Physical Impacts of Mood, Positive Outlook, Positive Psychology, Positive Psychosocial Factors, Proceedings of the National Academy of Sciences (PNAS), Proceedings of the National Academy of Sciences of the United States of America (PNAS), Psychosocial Protective and Risk Factors, Reducing the Divide Between Mental and Physical Healthcare, Revised Optimism–Pessimism Scale from the Minnesota Multiphasic Personality Inventory-2, United States, US Department of Veterans Affairs, USA, User-Generated Content: the BBC UGC Hub, Veterans Affairs Boston Healthcare System, Veterans Affairs Normative Aging Study, Veterans Affairs Normative Aging Study (NAS), Wellbeing and Longevity | Leave a comment

Eye Tests for Early Detection of Alzheimer’s Disease? (NHS Digital / Ophthalmology Retina)

Posted on March 20, 2019 by Dementia and Elderly Care News

Summary Further discussion about the possibilities of using inexpensive eye tests to detect Alzheimer’s Disease, perhaps years before symptoms appear. This particular technique involves the examination of blood vessels and blood flow in the retina, as detected by Octa (Optical … Continue reading →

Posted in Diagnosis, For Doctors (mostly), For Nurses and Therapists (mostly), For Researchers (mostly), In the News, International, NHS Digital (Previously NHS Choices), Quick Insights, Universal Interest | Tagged Alzheimer's Disease: Diagnosis, Alzheimer’s Disease, Alzheimer’s Disease and Dementia, Alzheimer’s Disease Biomarkers, Assessment and Diagnosis, Bazian, Behind the Headlines, Biomarkers, Biomarkers Predicting Cognitive Decline and Alzheimer's Disease, Central Subfield Thickness (CST), Cognitive Impairment, Critical Appraisals, Dementia Case Finding, Dementia Diagnosis, Dementia Screening, Diagnosis, Diagnosis of Alzheimer's Disease, Diagnostics, Duke University in North Carolina, Early Diagnosis, Early Diagnosis of Alzheimer's Disease, Early Treatment Diabetic Retinopathy Study, Eye Examinations, Foveal Avascular Zone (FAZ) Area, Karen L. Wrenn Alzheimer's Disease Award, Macular Ganglion Cell-Inner Plexiform Layer (GC-IPL), MCI: Mild Cognitive Impairment, Mild Cognitive Impairment, National Institutes of Health, National Institutes of Health (NIH), National Institutes of Health (US), Neurodegeneration, Neurodegenerative Disease Research, Neurodegenerative Diseases, NHS Digital (Formerly NHS Choices), Non-Invasive Biomarkers, Octa: Optical Coherence Tomography Angiography, Ophthalmology Retina, Optical Coherence Tomography, Optical Coherence Tomography Angiography (OCTA), Preclinical Alzheimer's Disease, Rapid Screening, Research to Prevent Blindness Inc. (New York), Retina as Early Biomarker of Neurodegeneration, Retinal Biomarkers, Retinal Examination in Neurodegenerative Diseases, Retinal Microvascular and Neurodegenerative Changes in Alzheimer’s Disease, Retinal Microvascular and Neurodegenerative Changes in Mild Cognitive Impairment, Retinal Vessel Density (VD), Screening, Screening for Dementia, Timely Diagnosis, US National Institutes of Health (NIH), USA | Leave a comment

Dementia Medication De-Listed in France: Untruth, Half-Truth or Paternalistic News Blackout? (BBC News / Prescrire / ADI / Inside Health / JAMA Network Open)

Posted on October 18, 2018 by Dementia and Elderly Care News

Summary Early evening headlines yesterday, on BBC Radio 4 news, announced the “shocking” news that drugs for Alzheimer’s Disease / dementia had been de-listed in France. This story has not been followed-up, and appears to have been dropped quietly; although … Continue reading →

Posted in Alzheimer’s Disease International (ADI), Universal Interest | Tagged Adverse Drug Reactions, Adverse Effects, Alpha-7 Nicotinic Acetylcholine Receptor (α7nAChR), Alzheimer's Disease: Monotherapy Versus Combination Therapy, Alzheimer's Research and Therapy, Alzheimer’s Disease International (ADI), Alzheimer’s Disease International (ADI) Campaigns, American Family Physician, Anti-Dementia Medication, Augusta University, BBC Radio 4, BBC Radio 4's Inside Health Programme, BBC Radio 4’s PM Programme, Big Pharma, BMJ, BMJ Publishing Group Ltd, British Medical Journal (BMJ), Cambridge Institute of Public Health: University of Cambridge, Care of the Elderly Medicine Department: Royal Wolverhampton NHS Trust, Cholinergic-Nicotinic System, Choosing Wisely, Clinic for Medicine of the Elderly (Hannover), Conflict of Interests, Conflicts of Interest, Department of Behavioral Neuroscience and Drug Development: Polish Academy of Sciences, Department of Psychiatry and Behavioral Health: Marshfield Clinic Health System, Department of Psychiatry and Behavioral Sciences: George Washington University School of Medicine and Health Sciences, Department of Psychiatry and Health Behavior: Augusta University, Department of Public Health and Primary Care: University of Cambridge, Deprescribing, Donepezil, Donepezil-Memantine Combination, Donepezil-Memantine: Monotherapy Versus Combination Therapy, Drug Efficacy, Drug Side-Effects, Drugs Alleged to Raise False Hopes (Speculative Construct), Family Medicine Residency Program: Southern Illinois University School of Medicine, Family Physicians Inquiries Network (FPIN), Formindep: Non-Profit Organisation Promoting Independence From Industry Influence, France, France's National Authority for Health (HAS), French Ministry of Health and Solidarity, French National Dementia Guidelines, Galantamine, Galantamine-Memantine Combination Versus Donepezil-Memantine Combination, Galantamine-Memantine Drug Combination, George Washington University School of Medicine and Health Sciences, Germany, Glutamatergic Receptor Systems, Glutamatergic System, Harms of Too Much Medicine, Institute of Pharmacology: Polish Academy of Sciences, JAMA Network Open, Janssen Research and Development, Journal of Geriatric Care and Research (JGCR), Keck School of Medicine: University of Southern California, KYNA/3-HK, KYNA/KYN, KYNA/QUIN, Kynurenic Acid, Kynurenine Pathway, Marshfield Clinic Health System (USA), Medical College of Georgia: Augusta University, Memantine, Ministry of Health and Solidarity (France), Mismatch Negativity (MMN), Mount Sinai Medical Center (New York), National Institutes of Health (NIH), National Institutes of Health (US), Neurotransmitter Systems in Alzheimer’s Disease, New Cross Hospital, New Cross Hospital: Royal Wolverhampton NHS Trust, NMDA (N-Methyl-D-Aspartate), Over-Treatment, Oxidative Stress, Paola Barbarino: Alzheimer’s Disease International, Pharmaceutical Journal, Poland, Polish Academy of Sciences, Prescrire in English [the Prescriber] / Rev. Prescrire, Psychosocial Approaches to Dementia Support, Psychosocial Approaches to Dementia: Storytelling Music and Song, Reducing Waste in Dementia Care, Reducing Waste in the NHS, Rivastigmine, Royal Wolverhampton NHS Trust, Serge Gauthier: ADI’s Medical and Scientific Advisory Panel (MSAP), Society of Biological Psychiatry (SOBP), Southern Illinois University, Southern Illinois University School of Medicine, Synaptec Inc (Florida), Too Much Medicine, United States, University of Alabama at Birmingham, University of Cambridge, University of Southern California, USA | Leave a comment

More on International Comparisons in Life Expectancy: The Impact of Austerity? (BBC News / ONS / BMJ / NHS Choices / King’s Fund)

Posted on August 13, 2018 by Dementia and Elderly Care News

Summary Increases in life expectancy in the UK may be slowing down; possibly at the fastest rate among the top twenty leading world economies. This slowdown effect was most apparent in women, where the rate of rising life expectancy fell … Continue reading →

Posted in BBC News, Charitable Bodies, Community Care, For Doctors (mostly), For Nurses and Therapists (mostly), For Researchers (mostly), In the News, International, King's Fund, National, NHS Digital (Previously NHS Choices), Statistics, Universal Interest | Tagged Ageing Population, Ageing Research, Ageing Society, Austerity, Australia, Austria, Bazian, BBC Health News, BBC's Life Expectancy Calculator, Behind the Headlines, Belgium, Canada, Changing Trends in Mortality in England and Wales: 1990 to 2017, Changing Trends in Mortality: Cross-UK Comparison - 1981 to 2016 (ONS), Changing Trends in Mortality: International Comparisons, Critical Appraisals, Declines in Life Expectancy, Denmark, Finland, Germany, Health Equity in England: The Marmot Review 10 Years On, Health Inequalities, Health Inequalities in England, Human Mortality Database, Human Mortality Database (HMD), Increasing Life Expectancy: Trends and Comparisons, International Comparisons, Italy, Japan, Leonard Davis School of Gerontology and Department of Sociology: University of Southern California, Life Expectancy, Life Expectancy by Neighbourhood, Life Expectancy Gaps, Life Expectancy of Poorest Women, Life Expectancy: Inequalities, London School of Hygiene and Tropical Medicine, Marmot Review (2020): Ten Years On, Mortality Data from the Office for National Statistics, National Institutes of Health (NIH), National Institutes of Health (US), Netherlands, Norway, Office for National Statistics (ONS), Office of Population Research and Department of Sociology: Princeton University, PHE Review of Recent Trends in Mortality in England, Poorest Women’s Life Expectancy, Portugal, Princeton University, Professor Martin McKee: European Public Health at London School of Hygiene and Tropical Medicine, Public Health England (PHE), Robert Cuffe: BBC News Head of Statistics, Robert Wood Johnson Foundation (RWJF), Sir Steve Webb: Former Liberal Democrat Pensions Minister, Spain, Sweden, Switzerland, Trends in Life Expectancy: International Comparisons, Trends in Longevity in England, Trends in Mortality in England, United Kingdom, United States, University of Southern California, US National Institutes of Health, USA | Leave a comment

Future Director of the UK Dementia Research Institute (MRC / Guardian / JAMA Neurology)

Posted on December 14, 2016 by Dementia and Elderly Care News

Summary Professor Bart De Strooper has been appointed as the Director of the UK Dementia Research Institute (UK DRI). Prof. De Strooper currently leads the Laboratory for the Research of Neurodegenerative Diseases at the University of Leuven and is scientific … Continue reading →

Posted in For Researchers (mostly), In the News, International, Models of Dementia Care, National, Quick Insights, UK, Universal Interest | Tagged Ageing Population, Belgium, Biomarker Development, Biomarkers, Biomarkers Research Programmes, Brain Imaging, Dementia and Alzheimer's Disease: Leading Cause of Death in 2015, Dementia Challenge 2020, Dementia Research, Dementia Research Careers, Dementia Research Institute (DRI), Dementia Research: Roadmap for the Next Decade, Department of Neuroscience: Mayo Clinic Florida, Diagnostic Imaging, Diagnostics, Disease Modifying Treatment by 2025 (Aim), Disease-Modifying Therapies, Disease-Modifying Therapies for Dementia, Drug Discovery Programmes, Environmental Risk Factors, Epidemiology, G8 Dementia Summit Declaration, Genetics, Global Action Against Dementia, Global Context, Global Leadership, Guardian, Guardian (Newspaper), International Dementia Research, International Dementia Research Inventories, JAMA Neurology, Jo Johnson: Universities and Science Minister, Johns Hopkins University, Laboratory for the Research of Neurodegenerative Diseases: University of Leuven, Laboratory of Neurogenetics: National Institute on Aging, Lifestyle Risk Factors, Mayo Clinic Florida, Medical Research Council (MRC), Medical Research Council (UK), Michael Arthur: UCL President and Provost Professor, MRC: Medical Research Council, National Institutes of Health (NIH), National Institutes of Health (US), National Institutes of Health / National Institutes on Aging, Neurodegenerative Disease Research, Neurodegenerative Diseases, Neurodegenerative Disorders, Neurodegenerative Research, Neuroimaging of Dementia, Neurology, Neuromuscular Diseases Research Section: National Institute on Aging, Neuroscience, Overlapping Risk Factors, Potential Drug Targets, Preclinical Biomarkers and Dementia, Professor Bart De Strooper: Director of the UK Dementia Research Institute (UK DRI), Recruitment of Research Leaders / Rising Stars, Research and Development, Research and Innovation, Research Commitment, Sir John Savill: Chief Executive of the Medical Research Council, UCL DRI Hub, UK Dementia Research Institute, UK Dementia Research Institute (UK DRI), United States, University College London (UCL), University of Leuven, US National Institutes of Health, US National Institutes of Health (NIH), USA, VIB (Belgium), VIB-K.U.Leuven | Leave a comment

Developments in Dementia Research: From the Horses’ Mouths (NHS England / NIHR)

Posted on August 25, 2016 by Dementia and Elderly Care News

Summary Professor Alistair Burns (NHS England’s National Clinical Director for Dementia and Older Peoples’ Mental Health), and Professor Martin Rossor (NIHR National Director for Dementia Research), discuss current issues and new approaches in dementia research, touching briefly upon some of … Continue reading →

Posted in For Doctors (mostly), For Nurses and Therapists (mostly), For Researchers (mostly), International, Mental Health, Models of Dementia Care, National, NHS England, NIHR, Pharmacological Treatments, Quick Insights, UK, Universal Interest | Tagged 100000 Genomes Project, A4 Study, Alistair Burns: Honorary Consultant Old Age Psychiatrist in the Manchester Mental Health and Social Care Trust (MMHSCT), Alistair Burns: NHS England’s National Clinical Director for Older People’s Mental Health, Alistair Burns: Professor of Old Age Psychiatry at University of Manchester, Alzheimer's Prevention Initiative, Alzheimer’s Disease Biomarkers, Alzheimer’s Prevention Initiative Study, Anti-Amyloid Treatment in Asymptomatic Alzheimer’s Study (A4 Study), APP and Presenilin, Asymptomatic Alzheimer’s Disease, Banner Alzheimer's Institute, Biomarkers, Chance Genetic Mutations, Colombia, Colombian Alzheimer's Prevention Initiative Registry in Medellín Antioquia, DIAN-TU Study, DIAN-TU Trial, Disease Modifying Treatment by 2025 (Aim), Disease-Modifying Therapies, Disease-Modifying Therapies for Dementia, Dominantly Inherited Alzheimer Network Trials Unit (DIAN-TU), Early Detection of Alzheimer’s Disease, Early Detection of Preclinical Disease, Genentech, Genomics, Genomics England, Genomics in the NHS, Genomics-Based Medicine, Global Outlook, Identification of People At Risk of Dementia, International Collaborations, International Programmes, International Research, Medellin (Colombia), Monoclonal Antibodies, MRC Neurochemical Pharmacology Unit, Mutational Signatures, National Clinical Director for Dementia, National Institute for Health Research (NIHR), National Institutes of Health (NIH), National Institutes of Health (US), Neurodegeneration, Neurodegenerative Disease Research, Neurodegenerative Diseases, Neurodegenerative Disorders, Neurodegenerative Research, NIHR Clinical Research Network, NIHR Dementia Translational Research Collaboration, NIHR National Director for Dementia Research, NIHR Translational Research Collaboration, Overcoming Barriers, Participation in Research, Participation in Research Studies, Preclinical Alzheimer's Disease, Presenilin, Prodromal Alzheimer's Disease, Professor Alistair Burns, Professor Martin Rossor: Director of the NIHR Queen Square Dementia Biomedical Research Unit, Professor Martin Rossor: Former Director of the NIHR Dementia and Neurodegenerative Disease Research Network (DeNDRoN), Professor Martin Rossor: Former President of the Association of British Neurologists (2011-2013), Professor Martin Rossor: Honorary Consultant Neurologist at National Hospital for Neurology and Neurosurgery, Professor Martin Rossor: National Hospital (Queen Square), Professor Martin Rossor: NIHR National Director for Dementia Research, Professor Martin Rossor: UCL Institute of Neurology, Promisary Science, Reducing Downstream Effects of Disease, Research and Development, Research and Innovation, Research Commitment, Research Culture, Research Mapping, Research Networks, Research Promotion, Sharing Knowledge and Information, Slowing Progression of Disease (Stabilisation), Solanezumab (Sola or Solab), Solanezumab: Humanised Monoclonal Antibody, Therapeutic Nihilism (Avoiding), Translational Research, UK Genomes Project: Genomics England, University of Southern California’s Alzheimer’s Therapeutic Research Institute, Washington University School of Medicine | Leave a comment

Early Indications Suggest Zika Virus Might Damage Adult Brains Resulting in Long-Term Neurological Conditions (NHS Choices / Cell Stem Cell)

Posted on August 20, 2016 by Dementia and Elderly Care News

Summary The Zika virus has been linked with microcephaly in human babies, and has also – more tentatively – been linked to Guillain-Barre Syndrome (GBS), but until now was not thought likely to affect the adult population beyond minor short-term … Continue reading →

Posted in Animal Studies, For Doctors (mostly), For Nurses and Therapists (mostly), For Researchers (mostly), In the News, International, NHS Digital (Previously NHS Choices), Quick Insights, Universal Interest | Tagged Aging and Stem Cell Regeneration: Sanford Burnham Prebys Discovery Institute, Apoptosis and Reduced Cellular Proliferation, Apoptotic Neural Cell Death, Behind the Headlines, California Institute of Regenerative Medicine, Caribbean Countries, Cell Stem Cell (Journal), Central America, Central Nervous System Abnormalities, CNS Infections, Del. E. Webb Center for Neuroscience: Sanford Burnham Prebys Discovery Institute, Dementia Risk Factors, Dengue Virus, Department of Neurosciences: University of California, Division of Inflammation Biology: La Jolla Institute for Allergy and Immunology, Environmental Risk Factors, Flaviviruses, Genetically Engineered Mice, Guillain-Barré Syndrome, Guillain-Barre Syndrome (GBS), Hippocampus, Hippocampus-Based Cognitive Processes, Howard Hughes Medical Institute, Howard Hughes Medical Institute: Rockefeller University, Infection, Infection and Infectious Diseases, La Jolla Institute for Allergy and Immunology, La Jolla Institute for Genomic Medicine, Laboratory for Pediatric Brain Diseases: Howard Hughes Medical Institute, Long Term Neurological Conditions, Microcephaly, National Institutes of Health (NIH), National Institutes of Health (US), Neural Progenitor Cells (NPCs), Neurobiology of ZIKV and Potential Neuropsychiatric Manifestations, Neurogenesis, Neurological Complications, Neurological Conditions, Neurological Disease, Neurological Disorders, Pathogenesis, Rady Children’s Institute for Genomic Medicine: University of California, Risk Factors, Risks to Immunocompromised Adults, Rockefeller University, Sanford Burnham Prebys Discovery Institute, Simons Foundation of Autism Research Initiative, South America, Subgranular Zone (SGZ) of Hippocampus, Subventricular Zone (SVZ) of Anterior Forebrain, Systemic ZIKV Can Infect Neural Progenitor Cells in the Adult Brain, The Americas, TKO Mice (Mice With Immune Cells Knocked Out), United States, University of California, USA, World Health Organization (WHO): Zika Public Health Emergency of International Concern, Zika Fever, Zika Infection Leading to Neural Cell Death and Reduced Cell Division, Zika Virus, Zika Virus (ZIKV) Infection, Zika Virus Epidemiology and Recent Epidemics, Zika Virus Infection: Public Health Issues, Zika Virus Outbreaks in the Americas, ZIKV Pandemic | Leave a comment

Tag Archives: National Institutes of Health (NIH)

Eye Tests for Early Detection of Alzheimer’s Disease? (NHS Digital / Ophthalmology Retina)

Dementia Medication De-Listed in France: Untruth, Half-Truth or Paternalistic News Blackout? (BBC News / Prescrire / ADI / Inside Health / JAMA Network Open)

More on International Comparisons in Life Expectancy: The Impact of Austerity? (BBC News / ONS / BMJ / NHS Choices / King’s Fund)

Future Director of the UK Dementia Research Institute (MRC / Guardian / JAMA Neurology)

Early Indications Suggest Zika Virus Might Damage Adult Brains Resulting in Long-Term Neurological Conditions (NHS Choices / Cell Stem Cell)

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