Tag Archives: Nature

New Uncertainties Around Irreversible Brain Cell Death Following Oxygen Deprivation? (BBC News / Nature)

Summary Conventional medical wisdom holds that brain cells and working brain circuitry are prone to irreversible damage following merely minutes of interrupted blood flow and disrupted oxygen supply. Researchers at Yale University used an extracorporeal pulsatile-perfusion system to restore circulation in … Continue reading

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Blood Test for Pre-Symptomatic Alzheimer’s Disease Likely to Arrive Soon? (BBC News / Nature)

Summary A blood test developed by researchers in Australia and Japan appears to be able to predict the risk of developing Alzheimer’s Disease, with 90% accuracy. Detection of amyloid beta in the blood may be taken as a biomarker for … Continue reading

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Structure of Tau Filaments in Alzheimer’s Disease Discovered (MRC / BBC News / Nature / NHS Choices)

Summary Research at the MRC Laboratory of Molecular Biology has taken advantage of a “resolution revolution” in microscopy to uncover the atomic structure of Tau filaments (one of the two types of the abnormal tangles associated with Alzheimer’s Disease). “Tau forms … Continue reading

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Chief Medical Officer’s Generation Genome Report (BBC News / Department of Health / Bazian / Nature)

Summary The latest annual report from Professor Dame Sally Davies, the Chief Medical Officer (CMO) for England unveils a “genomic dream” vision, whereby whole genome screening (WGS) might soon become standard practice in the NHS, much like blood tests and biopsies. … Continue reading

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Further Research Backs Speculation Linking the Immune System and Parkinson’s Disease (BBC News / Nature)

Summary Further evidence has emerged suggesting that malfunctioning in the body’s immune system may contribute to the development and progression of Parkinson’s Disease. T-cells appear to attack alpha-synuclein – a protein which accumulates in Parkinson’s Disease – after confusing this … Continue reading

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The Reproducibilty Problem / Replication Crisis in Science: a Pervasive Issue in Medicine? (BBC News / Nature / Elife)

Summary It has been estimated that between 65% and 90% of researchers typically fail to reproduce fellow scientists’ research results. The Reproducibility Project: Cancer Biology has raised awareness of the prevalence of this problem in biomedical science. The issues are … Continue reading

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Flashing Light: A Potential Alternative to Drug Treatment to Prevent Amyloid Plaque Formation? (BBC News / Nature)

Summary Animal research on genetically modified mice suggests that a specialised form of flashing light therapy might help slow the progression of Alzheimer’s Disease. It appears that shining a strobe light, flashing at a rate of 40Hz, into rodents’ eyes … Continue reading

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A Natural Limit to Human Life Expectancy? (BBC News / Nature)

Summary Despite recent historical trends in the seemingly endless increase in human life expectancy, researchers analysing global demographic data believe they may have detected signs that the maximum lifespan may be limited to around 115 years “Our results strongly suggest … Continue reading

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Memories Lost in Alzheimer’s Disease: Potentially Retrievable? (NHS Choices / Nature)

Summary Research on transgenic mice suggests that memories are not destroyed irretrievably by Alzheimer’s Disease; there appears to be problems recalling these lost memories. Lost memories may be retrievable, under experimental conditions, by exposing “Engram Cells” with bright blue light … Continue reading

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Potential Risk of Alzheimer’s Disease Transmission (BBC News / NHS Choices / Nature / MRC)

Summary There may be a theoretical risk of Alzheimer’s Disease being transmissible during surgical procedures, in the manner of Creutzfeldt-Jakob disease (CJD). This hypothesis has arisen as a result of the examination of the brains of eight patients who had … Continue reading

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