Tag Archives: Neurodegenerative Diseases

More on the Association Between Brain Injury and Subsequent Dementia (BBC News / Lancet Psychiatry)

Posted on April 11, 2018 by Dementia and Elderly Care News

Summary A large-scale statistical study, based on Danish data, indicates that persons who suffer traumatic brain injury (TBI) tend to be 24% more likely to get dementia later on. The greatest risk appears to be for people who receive TBI … Continue reading →

Posted in BBC News, For Doctors (mostly), For Nurses and Therapists (mostly), For Researchers (mostly), In the News, International, NHS Choices, Quick Insights, Statistics, Universal Interest | Tagged Aarhus University Hospital, Aarhus University Hospital (Denmark), Bazian, BBC Health News, Behind the Headlines, Brain Injury, Cambridge Institute of Public Health, Cambridge Institute of Public Health: University of Cambridge, Cognitive Decline, Copenhagen University Hospital, Critical Appraisals, Danish Civil Registration System, Danish National Health Registry, Danish National Patient Register (NPR), Danish National Prescription Registry, Danish National Prescription Registry (DNPR), Danish Psychiatric Central Register, Dementia Risk Factors, Denmark, Department of Neurology: Aarhus University Hospital, Department of Psychiatry and Behavioral Sciences: University of Washington, Department of Public Health: Aarhus University, Epidemiology, Epidemiology and Statistics, Lancet Psychiatry, Lundbeck Foundation (Denmark), Mental Health Centre Copenhagen, National Patients Register (Danish NPR), Neurodegeneration, Neurodegenerative Diseases, Recall Bias (Potential), Research Unit for General Practice and Section for General Medical Practice: Aarhus University, Traumatic Brain Injury, Traumatic Brain Injury (TBI), Traumatic Brain Injury and Subsequent Dementia, United States, University of Washington, University of Washington (Seattle), USA | Leave a comment

Diagnosis of Primary Progressive Aphasia (JGCR / Journal of Neurology / ARUK)

Posted on April 2, 2018 by Dementia and Elderly Care News

A Journal of Geriatric Care and Research (JGCR) case report discusses the neuropsychological assessments preparatory to the differential diagnosis of Primary Progressive Aphasia (PPA). PPA is a rare form of non-Alzheimer’s dementia featuring language impairment with progressive decline in word … Continue reading →

Preventative Treatment to Reduce Risk of Alzheimer’s Disease, Using Non-Steroidal Anti-Inflammatory Drugs? (NHS Choices / Journal of Alzheimer’s Disease)

Posted on March 31, 2018 by Dementia and Elderly Care News

Summary A recent article suggests that use of nonsteroidal anti-inflammatory drugs (NSAIDs) might help to reduce the risk of developing Alzheimer’s Disease, if prescription were to be commenced years before clinical signs were to develop. An NHS Choices Behind the … Continue reading →

Posted in For Doctors (mostly), For Nurses and Therapists (mostly), For Researchers (mostly), In the News, International, NHS Choices, Pharmacological Treatments, Quick Insights, Universal Interest | Tagged Aβ42, Alzheimer Disease Anti-Inflammatory Prevention, Alzheimer’s Disease Biomarkers, Amyloid Beta (Aβ42), Amyloid Beta Protein, Amyloid Cascade Inflammatory Hypothesis, Amyloid-β (Aβ), Amyloidogenic and Inflammatory Pathways, Aurin Biotech, Aurin Biotech Inc. Ltd. (Vancouver), ß-amyloid, Bazian, Behind the Headlines, Biomarkers, Canada, Critical Appraisals, Dementia Risk Reduction and Prevention, Dementia Saliva Testing (Pilot Study), Diagnosis of Alzheimer's Disease Based on Salivary Amyloid-β Protein 42 Levels, ELISA Method to Determine Aβ42 Levels in Saliva, Fluid Biomarker Analysis, Ibuprofen, Ibuprofen and the Reduced Risk of Alzheimer’s Disease Link, Inflammation, Journal of Alzheimer's Disease, Long-Term Ibuprofen Use, Neurodegenerative Disease Research, Neurodegenerative Diseases, Neurodegenerative Disorders, Neurodegenerative Research, Neuroinflammation, Non-Invasive Biomarkers, Non-Steroidal Anti-Inflammatory Drugs (NSAIDS), NSAIDS: Non-Steroidal Anti-Inflammatory Drugs, Preclinical Biomarkers in Alzheimer's Disease, Preventative Interventions, Prevention, Saliva Tests, Salivary Amyloid-β Protein 42 Levels, Salivary Biomarkers | Leave a comment

Dementia Researchers Recognised and Rewarded (BBC News / Lundbeck Foundation)

Posted on March 7, 2018 by Dementia and Elderly Care News

Summary Four dementia researchers share the 2018 (€1 million Euro) Brain Prize (bestowed by the Lundbeck Foundation), in recognition of their joint work on the underlying neuropathological mechanisms thought to cause of Alzheimer’s Disease. Full Text Link Reference Roberts, M. … Continue reading →

Posted in BBC News, For Doctors (mostly), For Nurses and Therapists (mostly), For Researchers (mostly), In the News, International, Quick Insights, UK, Universal Interest | Tagged Abnormal Proteins, Abnormal Proteins (Tau), Alzheimer’s Disease, Alzheimer’s Disease and Dementia, Alzheimer’s Disease: Causes, Amyloid Beta Protein, Amyloid Cascade Hypothesis, Amyloid Proteins, Amyloid-β Protein, Annual €1 Million Brain Prize, Apolipoprotein E (APOE) Gene, Asymptomatic Alzheimer’s Disease, Cambridge University, Dementia Research, Dementia Research Careers, Dementia Research Funding, Genetic Research, Germany, Global Context, Global Dementia Research, Global Outlook, β-Amyloid Precursor Protein (APP), Lundbeck Foundation (Denmark), Neurodegeneration, Neurodegenerative Disease Research, Neurodegenerative Diseases, Neurodegenerative Disorders, Neuropathologic Disorders, Neuropathology, Pathophysiological Processes in Alzheimer’s Disease, Professor Bart De Strooper: Director of the UK Dementia Research Institute (UK DRI), Professor Christian Haass, Professor John Hardy, Professor Michael Goedert, The Brain Prize (Lundbeck Foundation), UK Dementia Research Institute, UK Dementia Research Institute (UK DRI), UK Dementia Research Institute at UCL, University College London, University of Munich | Leave a comment

Deep Brain Stimulation for Improving Symptoms in Alzheimer’s Disease (BBC News)

Posted on January 30, 2018 by Dementia and Elderly Care News

Summary A brief BBC News item explores the potential of deep brain stimulation (DBS) therapy for improving wellbeing and cognitive function in patients with Alzheimer’s Disease and other forms of dementia. “Although we are not talking about treating the Alzheimer’s … Continue reading →

Posted in BBC News, For Carers (mostly), For Doctors (mostly), For Nurses and Therapists (mostly), For Researchers (mostly), In the News, International, Management of Condition, Mental Health, Models of Dementia Care, Non-Pharmacological Treatments, Quick Insights, Universal Interest | Tagged Alzheimer's Disease, Andres Lozano (Neurosurgeon), Brain Imaging, Canada, Deep Brain Stimulation, Deep Brain Stimulation (DBS), Deep Brain Stimulation for the Treatment of Alzheimer Disease, Deep Brain Stimulation for the Treatment of Dementia, Deep Brain Stimulation of Nucleus Basalis of Meynert (NBM DBS), Dr Carol Routledge: Alzheimer's Research UK, LaVonne Moore, Neurodegeneration, Neurodegenerative Diseases, Neurological Disease, Nucleus Basalis of Meynert, Nucleus Basalis of Meynert (NBM), Ohio State University Wexner Medical Center, Parkinson’s Dementia, Parkinson’s Disease Dementia, Treatment of Alzheimer's Disease, United States, USA, Wexner Medical Center: Ohio State University | Leave a comment

No Room For Complacency Regarding Population Subclinical vCJD? (PLoS Pathogens)

Posted on January 22, 2018 by Dementia and Elderly Care News

Summary After a near-miss mini-epidemic of Variant Creutzfeldt-Jakob Disease (vCJD) in the 1990s, experts caution that: “It is essential that we do not become complacent and continue both surveillance and risk management strategies in both human and animal prion diseases”. … Continue reading →

Posted in Universal Interest | Tagged Biomarkers, Biotechnology and Biological Sciences Research Council (BBSRC), Blood Organ and Tissue Donation, Blood Transfusions, Blood-Based Biomarkers, Bovine Spongiform Encephalopathy (BSE), BSE Exposure, Centre for Dementia Prevention: University of Edinburgh, CJD, CJD Risk Management, CJD Surveillance, Creutzfeldt-Jakob Disease (CJD), Creuzfeldt Jacob Disease (CJD), Decontamination of Surgical Instruments, Dementia Prevention, Diack and Manson Laboratories, Donor Blood, Edinburgh Neuroscience, Edinburgh Neuroscience: University of Edinburgh, Epidemiology, Epidemiology and Statistics, Hypothetical Prodromes of Dementia, Infectivity of vCJD Infection, Mad Cow Disease, Medical Instruments, Medical Procedures, Misfolded Prion Protein (PrP), National CJD Research and Surveillance Unit (NCJDRSU), National CJD Research and Surveillance Unit: University of Edinburgh, National Institute for Health Research (NIHR) Policy Research Programme, NCJDRSU: National CJD Research and Surveillance Unit, Neurodegeneration, Neurodegenerative Disease Research, Neurodegenerative Diseases, PLoS Pathogens, Prevalence of CJD, Prion Diseases, Prionics Blood Test, Public Health, Public Health Risk, Public Health Surveillance, Roslin Institute (Edinburgh), Roslin Institute [and] R(D)SVS: University of Edinburgh, Subclinical vCJD, UK Blood Supply, University of Edinburgh, Variant CJD and Blood, Variant Creutzfeldt-Jakob Disease, vCJD Blood Testing, vCJD Carriers in UK, vCJD Infection | Leave a comment

The Most Significant Breakthrough in the Treatment of Neurodegenerative Diseases in Fifty Years? (BBC News / UCL)

Posted on December 15, 2017 by Dementia and Elderly Care News

Summary An experimental drug for the treatment of Huntington’s Disease shows early signs of being able to lower the level of misfolded proteins (safely) in the brains of patients, thereby having the potential to slow or halt the progression of … Continue reading →

Posted in BBC News, For Carers (mostly), For Doctors (mostly), For Nurses and Therapists (mostly), For Researchers (mostly), In the News, Parkinson's Disease, Quick Insights, UK, Universal Interest | Tagged Alzheimer's Disease, Amyloid Beta, Amyloid Beta Protein, Amyloid Proteins, Antisense Oligonucleotides (ASO), Biomedical Research Centres (NIHR), Canada, Clinical Trial NCT02519036, Gene Silencing to Suppress Transcription and Translation of Huntingtin, Gene-Silencing, Genetic Research, Genetics, Germany, Huntingtin Protein, Huntingtin Protein (HTT), Huntington Disease, Huntington's Disease (HD): an Autosomal-Dominant Inherited Neurodegenerative Disorder, Huntington's Disease Centre: UCL Institute of Neurology, Huntington’s Disease, Ionis Pharmaceuticals, IONIS-HTTRx: Huntingtin-Lowering Drug, α-Synuclein, α-Synuclein Aggregation, Leonard Wolfson Experimental Neurology Centre (LWENC), Leonard Wolfson Experimental Neurology Centre: University College London, Misfolded Proteins, Mutant HTT (mHTT) Protein, Mutant Huntingtin (mHTT), National Institute for Health Research (NIHR), Neurodegeneration, Neurodegenerative Disease Research, Neurodegenerative Diseases, Neurodegenerative Disorders, Neuronal Loss, Neuroprotection, Prof. Giovanna Mallucci, Professor Sarah Tabrizi: IONIS-HTTRx Global Chief Investigator, Professor Sarah Tabrizi: UCL Institute of Neurology, Protein Misfolding, Roche, Synucleinopathy, Tau, Tau Protein, Tauopathy, University College London (UCL), University College London Hospitals Biomedical Research Centre, University College London Hospitals NHS Foundation Trust, University College London Hospitals NHS Foundation Trust / University College London (NIHR) Biomedical Research Centre | Leave a comment

Tag Archives: Neurodegenerative Diseases

More on the Association Between Brain Injury and Subsequent Dementia (BBC News / Lancet Psychiatry)

Preventative Treatment to Reduce Risk of Alzheimer’s Disease, Using Non-Steroidal Anti-Inflammatory Drugs? (NHS Choices / Journal of Alzheimer’s Disease)

Dementia Researchers Recognised and Rewarded (BBC News / Lundbeck Foundation)

Deep Brain Stimulation for Improving Symptoms in Alzheimer’s Disease (BBC News)

No Room For Complacency Regarding Population Subclinical vCJD? (PLoS Pathogens)

The Most Significant Breakthrough in the Treatment of Neurodegenerative Diseases in Fifty Years? (BBC News / UCL)

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