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Tag Archives: Neurodegenerative Diseases
Further Research Backs Speculation Linking the Immune System and Parkinson’s Disease (BBC News / Nature)
Summary Further evidence has emerged suggesting that malfunctioning in the body’s immune system may contribute to the development and progression of Parkinson’s Disease. T-cells appear to attack alpha-synuclein – a protein which accumulates in Parkinson’s Disease – after confusing this … Continue reading
Posted in BBC News, For Nurses and Therapists (mostly), For Researchers (mostly), In the News, International, Parkinson's Disease, Quick Insights, Universal Interest
Tagged Abnormal Proteins (Alpha-Synuclein), Adrienne Helis Malvin Medical Research Foundation (New Orleans), Alpha-Synuclein Aggregation, Alpha-Synucleinopathies, Australia, Autoimmune Attacks, BBC Health News, Brain and Immune System, Columbia University, Cytotoxic T Cell Responses, Department of Microbiology and Immunology: University of Oklahoma, Department of Neurology: Columbia University, Department of Pharmacology and Molecular Sciences: Johns Hopkins University School of Medicine, Department of Pharmacology: Columbia University, Department of Physiology: Johns Hopkins University School of Medicine, Departments of Psychiatry: Columbia University, Division of Molcular Therapeutics: New York State Psychiatric Institute, Division of Vaccine Discovery: La Jolla Institute for Allergy and Immunology, Histocompatibility Complex Alleles, Immune System, Immune System and Parkinson's Disease, Inflammation, Inflammation and Neurodegenerative Diseases, Institute for Cell Engineering and the Department of Neurology: Johns Hopkins University School of Medicine, Institute for Immunology and Infectious Diseases: Murdoch University, α-Synuclein, α-Synuclein Aggregation, α-Synuclein Misfolds, α-Synuclein Peptides, Johns Hopkins University School of Medicine, La Jolla Institute for Allergy and Immunology, Murdoch University (Perth; Western Australia), Nature, Nervous System and Immune System, Neurodegeneration, Neurodegenerative Disease Research, Neurodegenerative Diseases, Neurodegenerative Disorders, Neurodegenerative Research, Neuroregeneration and Stem Cell Program: Johns Hopkins University School of Medicine, New York State Psychiatric Institute, Novel Targets in Neurodegeneration, Solomon H. Snyder Department of Neuroscience: Johns Hopkins University School of Medicine, T-Cells, United States, University of Oklahoma, USA
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Huntington’s Disease: a Blood Test “Speedometer”? (BBC News / Lancet Neurology)
Summary Early research shows promise that a protein biomarker in the blood, called neurofilament light chain (NFL), which is released from damaged brain cells in Huntington’s Disease, may be the basis for a blood test able to predict whether people … Continue reading
Posted in BBC News, Diagnosis, For Researchers (mostly), In the News, International, Quick Insights, UK, Universal Interest
Tagged BBC Health News, Biomarker Development, Biomarkers, Biomarkers Research Programmes, Blood Tests, Blood-Based Biomarkers, Blood-Based Biomarkers of Pre-Symptomatic Huntington’s Disease, Blood-Based NfL, Canada, Carver College of Medicine: University of Iowa, Cath Stanley: Chief Executive of Hungtington's Disease Association, Centre for Molecular Medicine and Therapeutics: University of British Columbia, CHDI Foundation, Department of Neurology: Leiden University, Department of Psychiatry and Neurochemistry: Sahlgrenska Academy; University of Gothenburg, Department of Psychiatry: University of Iowa, European Research Council, France, Genetics Department: Pitié-Salpêtrière University Hospital, HTT, HTT Mutation Carriers, Huntington Disease, Huntington's Disease Centre: UCL Institute of Neurology, Huntington’s Disease, INSERM, Institut du Cerveau et de la Moelle épinière (ICM), Institute of Neuroscience and Physiology: Sahlgrenska Academy (University of Gothenburg), Institute of Neuroscience and Physiology: Sahlgrenska Academy at University of Gothenburg, Knut and Alice Wallenberg Foundation, Lancet Neurology, Leiden University, Leonard Wolfson Experimental Neurology Centre: University College London, Medical Research Council (MRC), Mutant Huntingtin (mHTT), National Hospital for Neurology and Neurosurgery, National Institute for Health Research UCL Hospitals Biomedical Research Centre, Netherlands, Neurodegeneration, Neurodegenerative Disease Research, Neurodegenerative Diseases, Neurodegenerative Disorders, Neurofilament Light Chain (NFL), Neurofilament Light Protein (NF-L), Neurofilament Light Protein in Blood: Potential Biomarker of Huntington's Disease, Neurofilament Light Protein in Blood: Potential Biomarker of Neurodegeneration, Non-Invasive Biomarkers, Pitié-Salpêtrière University Hospital (Paris), Plasma Biomarkers, Plasma Neurofilament Light Chain, Preclinical Biomarkers in Huntington's Disease, Protein-Based Biomarkers in Blood May Deliver Accurate Diagnoses, Sahlgrenska Academy at the University of Gothenburg, Sahlgrenska University Hospital (Sweden), Serum Neurofilament Light Chain Protein, Sorbonne Universités, Surrogate Biomarkers of Neurodegeneration, Sweden; Clinical Neurochemistry Laboratory: Sahlgrenska University Hospital, Swedish Research Council, Torsten Söderberg Foundation, Transforming Research and Clinical Knowledge in Huntington's Disease (TRACK-HD), UCL Institute of Neurology, University College London (UCL), University of British Columbia, University of Gothenburg, University of Iowa, UPMC University Paris 06: INSERM
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Conservative Manifesto on Social Care: Wiggle Room Re-Discovered to Avoid Toxic Dementia Tax (BBC News)
Summary Call it a re-balancing of emphasis, or call it a U-turn, there has been a welcome decision to consider setting an absolute maximum limit on the amount that individuals may have to contribute to their social care needs. The … Continue reading
Posted in BBC News, Community Care, For Carers (mostly), For Nurses and Therapists (mostly), For Researchers (mostly), For Social Workers (mostly), In the News, Management of Condition, National, Person-Centred Care, UK, Universal Interest
Tagged Adult Social Care, Adult Social Care Funding, Adult Social Care in England, Adult Social Care Services, Ageing and Dementia, Ageing and Society, Ageing Policy in the UK, Ageing Population, BBC Health News, BBC News Election 2017 Reality Check, BBC News Reality Check, Care Costs: Cap and Means Test, Care Funding, Care Home Costs, Care Home Fees, Care Tax (So-Called Dementia Tax), Caring and Family Finances, Catastrophic Care Costs, Conservative Manifesto (2017), Conservative Party’s 2017 Election Manifesto, Cost of Social Care for Older People, Dementia Tax, Dementia Tax (Alzheimer's Society), Dilnot Commission Recommendations, Dilnot Commission Report on Funding of Care and Support, Financial Constraints, Financial Context, Financial Issues, Financial Planning, Funding of Care and Support (Dilnot Commission), Health and Social Care Services, Home and Community Care Services, Home Care, Home Care Services, Long-Term Care (LTC), Long-Term Care and Support, Long-Term Conditions (LTCs), Means Test, Neurodegenerative Diseases, Neurodegenerative Disorders, Patient Safety Bill, Queen's Speech 2017, Self-Funders Subsidising the Social Care System, Self-Funding, Sir Andrew Dilnot, Social Care Crisis, State Funded Social Care, Stealth Death Tax: Chargable Against Families' Property Assets, Stealth Taxes, Sustainability, Theresa May Social Care U-Turn (2017), Tory Social Care Plans (2017)
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Earlier Diagnosis of Glaucoma – and Possibly Many Neurodegenerative Diseases – By Retinal Examination? (BBC News / NHS Choices / Brain)
Summary A fluorescent dye injected into the bloodstream may, in future, provide a convenient method of detecting glaucoma earlier – perhaps a decade before more overt symptoms and damage have had the opportunity to develop – by identifying changes in … Continue reading
Posted in BBC News, Diagnosis, For Doctors (mostly), For Nurses and Therapists (mostly), For Researchers (mostly), In the News, NHS Choices, Parkinson's Disease, Quick Insights, UK, Universal Interest
Tagged Annexin 5 Labelled With Fluorescent Dye DY-776 (ANX776), ANX776 Pharmacokinetics and Pharmacodynamics, ANX776-Positive Fluorescent Cells, Apoptosis, Apoptotic Cells in Neurodegenerative Diseases, Apoptotic Neural Cell Death, Assessment and Diagnosis, BBC Health News, Behind the Headlines, Bethan Hughes: Wellcome Trust, Brain (Journal), Centre for Medical Image Computing: University College London, DARC: Detection of Apoptosing Retinal Cells, Dementia Diagnosis, Department of Visual Neuroscience: UCL Institute of Ophthalmology, Detection of Apoptosing Retinal Cells (DARC), Diagnostic Imaging, Diagnostic Markers, Diagnostic Testing, Drusen (Spots on Retina), Early Diagnosis, Early Diagnosis of Alzheimer's Disease, Early Diagnosis of Parkinson’s Disease, Eye Cells, Eye Examinations, Glaucoma, Glaucoma and Retinal Neurodegeneration Group: UCL Institute of Ophthalmology, Glaucomatous Neurodegeneration, Imperial College London, Imperial College Ophthalmic Research Group (ICORG), Intravenous ANX776, Levels of Apoptosis (DARC Count), London, Neurodegeneration, Neurodegenerative Disease Research, Neurodegenerative Diseases, Neuronal Cell Apoptosis in Patients With Glaucoma, Neuronal Loss, Ocular Neurodegenerative Conditions, Potential of DARC as Surrogate Biomarker. Retinal Ganglion Cell Apoptosis, Retinal Assessments Using DARC (Detection of Apoptosing Retinal Cells), Retinal Cell Apoptosis, Retinal Ganglion Cell Layer, Retinal Nerve Fibre Layer (RNFL), Timely Diagnosis, Translational Imaging Group: University College London, UCL Institute of Ophthalmology, University College London, Western Eye Hospital, Western Eye Hospital: Imperial College Healthcare NHS Trust, Western Eye Hospital: Imperial College Healthcare NHS Trust (ICHNT)
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