Tag Archives: Neurodegenerative Disorders

Medicine to Ease Enlarged Prostate Re-Purposed for Parkinson’s Disease? (BBC News / Journal of Clinical Investigation)

Summary Terazosin, a drug developed originally to treat benign prostatic hyperplasia (BPH), may slow the progression of Parkinson’s Disease. It is thought that Terazosin may help by activating an enzyme (PGK1) which prevents cell death in the relevant brain regions. … Continue reading

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Time for a Complete Reset in Alzheimer’s Disease / Dementia Drugs Research: Never Too Late? (BBC News / Brain / NHS Digital)

Summary A new type of dementia, previously misdiagnosed as Alzheimer’s Disease, has been discovered to be prevalent in the oldest of old persons. Perhaps a third of elderly people earlier thought to have Alzheimer’s Disease may have had Limbic-predominant age-related … Continue reading

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More on Possible Blood Tests for Pre-Symptomatic Alzheimer’s Disease (NHS Digital / Nature Medicine)

Summary People with a rare hereditary form of Alzheimer’s Disease (Dominantly Inherited Alzheimer’s Disease) have raised levels of a protein called neurofilament light chain (NfC) in their blood, arising from damage to previously healthy nerve cells. These elevated levels of … Continue reading

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Dementia Research Centre in Wales (BBC News)

Summary A brief piece, from BBC News, on the work and aims of the £20 million Dementia Research Institute at Cardiff University. Full Text Link Reference Clarke, O. (2018). Fruit flies’ brains studied to help crack dementia. London: BBC Health … Continue reading

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Pre-Eclampsia and Risk of Dementia (BMJ)

Summary Danish research indicates that pre-eclampsia is associated with a subsequent increased risk of dementia in later life, particularly with vascular dementia. Full Text Link Reference Basit, S. Wohlfahrt, J. [and] Boyd, HA. (2018). Pre-eclampsia and risk of dementia later … Continue reading

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Risk of Dementia in Patients Using Antidepressants? (Behavioural Neurology / BBC News)

Summary Evidence indicating that use of antidepressants is associated significantly with an increased risk of developing dementia: Full Text Link Reference Wang, YC. Tai, PA. [and] Poly, TN. [et al] (2018). Increased risk of dementia in patients with antidepressants: a … Continue reading

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Hallucinations and Delusions in Dementia With Lewy Bodies (Behavioural Neurology)

Summary Hallucinations and delusions are common in Dementia with Lewy Bodies (DLB). A study shows that DLB patients who experience delusional symptoms tend to have poorer cognitive function and more severe BPSD. Oddly, DLB patients with diabetes appear to be less … Continue reading

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