Tag Archives: Neurodegenerative Disorders

Diagnosis of Primary Progressive Aphasia (JGCR / Journal of Neurology / ARUK)

Posted on April 2, 2018 by Dementia and Elderly Care News

A Journal of Geriatric Care and Research (JGCR) case report discusses the neuropsychological assessments preparatory to the differential diagnosis of Primary Progressive Aphasia (PPA). PPA is a rare form of non-Alzheimer’s dementia featuring language impairment with progressive decline in word … Continue reading →

Preventative Treatment to Reduce Risk of Alzheimer’s Disease, Using Non-Steroidal Anti-Inflammatory Drugs? (NHS Choices / Journal of Alzheimer’s Disease)

Posted on March 31, 2018 by Dementia and Elderly Care News

Summary A recent article suggests that use of nonsteroidal anti-inflammatory drugs (NSAIDs) might help to reduce the risk of developing Alzheimer’s Disease, if prescription were to be commenced years before clinical signs were to develop. An NHS Choices Behind the … Continue reading →

Posted in For Doctors (mostly), For Nurses and Therapists (mostly), For Researchers (mostly), In the News, International, NHS Choices, Pharmacological Treatments, Quick Insights, Universal Interest | Tagged Aβ42, Alzheimer Disease Anti-Inflammatory Prevention, Alzheimer’s Disease Biomarkers, Amyloid Beta (Aβ42), Amyloid Beta Protein, Amyloid Cascade Inflammatory Hypothesis, Amyloid-β (Aβ), Amyloidogenic and Inflammatory Pathways, Aurin Biotech, Aurin Biotech Inc. Ltd. (Vancouver), ß-amyloid, Bazian, Behind the Headlines, Biomarkers, Canada, Critical Appraisals, Dementia Risk Reduction and Prevention, Dementia Saliva Testing (Pilot Study), Diagnosis of Alzheimer's Disease Based on Salivary Amyloid-β Protein 42 Levels, ELISA Method to Determine Aβ42 Levels in Saliva, Fluid Biomarker Analysis, Ibuprofen, Ibuprofen and the Reduced Risk of Alzheimer’s Disease Link, Inflammation, Journal of Alzheimer's Disease, Long-Term Ibuprofen Use, Neurodegenerative Disease Research, Neurodegenerative Diseases, Neurodegenerative Disorders, Neurodegenerative Research, Neuroinflammation, Non-Invasive Biomarkers, Non-Steroidal Anti-Inflammatory Drugs (NSAIDS), NSAIDS: Non-Steroidal Anti-Inflammatory Drugs, Preclinical Biomarkers in Alzheimer's Disease, Preventative Interventions, Prevention, Saliva Tests, Salivary Amyloid-β Protein 42 Levels, Salivary Biomarkers | Leave a comment

Dementia Researchers Recognised and Rewarded (BBC News / Lundbeck Foundation)

Posted on March 7, 2018 by Dementia and Elderly Care News

Summary Four dementia researchers share the 2018 (€1 million Euro) Brain Prize (bestowed by the Lundbeck Foundation), in recognition of their joint work on the underlying neuropathological mechanisms thought to cause of Alzheimer’s Disease. Full Text Link Reference Roberts, M. … Continue reading →

Posted in BBC News, For Doctors (mostly), For Nurses and Therapists (mostly), For Researchers (mostly), In the News, International, Quick Insights, UK, Universal Interest | Tagged Abnormal Proteins, Abnormal Proteins (Tau), Alzheimer’s Disease, Alzheimer’s Disease and Dementia, Alzheimer’s Disease: Causes, Amyloid Beta Protein, Amyloid Cascade Hypothesis, Amyloid Proteins, Amyloid-β Protein, Annual €1 Million Brain Prize, Apolipoprotein E (APOE) Gene, Asymptomatic Alzheimer’s Disease, Cambridge University, Dementia Research, Dementia Research Careers, Dementia Research Funding, Genetic Research, Germany, Global Context, Global Dementia Research, Global Outlook, β-Amyloid Precursor Protein (APP), Lundbeck Foundation (Denmark), Neurodegeneration, Neurodegenerative Disease Research, Neurodegenerative Diseases, Neurodegenerative Disorders, Neuropathologic Disorders, Neuropathology, Pathophysiological Processes in Alzheimer’s Disease, Professor Bart De Strooper: Director of the UK Dementia Research Institute (UK DRI), Professor Christian Haass, Professor John Hardy, Professor Michael Goedert, The Brain Prize (Lundbeck Foundation), UK Dementia Research Institute, UK Dementia Research Institute (UK DRI), UK Dementia Research Institute at UCL, University College London, University of Munich | Leave a comment

The Most Significant Breakthrough in the Treatment of Neurodegenerative Diseases in Fifty Years? (BBC News / UCL)

Posted on December 15, 2017 by Dementia and Elderly Care News

Summary An experimental drug for the treatment of Huntington’s Disease shows early signs of being able to lower the level of misfolded proteins (safely) in the brains of patients, thereby having the potential to slow or halt the progression of … Continue reading →

Posted in BBC News, For Carers (mostly), For Doctors (mostly), For Nurses and Therapists (mostly), For Researchers (mostly), In the News, Parkinson's Disease, Quick Insights, UK, Universal Interest | Tagged Alzheimer's Disease, Amyloid Beta, Amyloid Beta Protein, Amyloid Proteins, Antisense Oligonucleotides (ASO), Biomedical Research Centres (NIHR), Canada, Clinical Trial NCT02519036, Gene Silencing to Suppress Transcription and Translation of Huntingtin, Gene-Silencing, Genetic Research, Genetics, Germany, Huntingtin Protein, Huntingtin Protein (HTT), Huntington Disease, Huntington's Disease (HD): an Autosomal-Dominant Inherited Neurodegenerative Disorder, Huntington's Disease Centre: UCL Institute of Neurology, Huntington’s Disease, Ionis Pharmaceuticals, IONIS-HTTRx: Huntingtin-Lowering Drug, α-Synuclein, α-Synuclein Aggregation, Leonard Wolfson Experimental Neurology Centre (LWENC), Leonard Wolfson Experimental Neurology Centre: University College London, Misfolded Proteins, Mutant HTT (mHTT) Protein, Mutant Huntingtin (mHTT), National Institute for Health Research (NIHR), Neurodegeneration, Neurodegenerative Disease Research, Neurodegenerative Diseases, Neurodegenerative Disorders, Neuronal Loss, Neuroprotection, Prof. Giovanna Mallucci, Professor Sarah Tabrizi: IONIS-HTTRx Global Chief Investigator, Professor Sarah Tabrizi: UCL Institute of Neurology, Protein Misfolding, Roche, Synucleinopathy, Tau, Tau Protein, Tauopathy, University College London (UCL), University College London Hospitals Biomedical Research Centre, University College London Hospitals NHS Foundation Trust, University College London Hospitals NHS Foundation Trust / University College London (NIHR) Biomedical Research Centre | Leave a comment

Mid-Life Blood Test for Inflammation May Predict Later-Life Dementia Risk? (NHS Choices / Neurology)

Posted on November 5, 2017 by Dementia and Elderly Care News

Summary Higher inflammatory marker scores in middle age, based on five blood-based markers of inflammation (fibrinogen, albumin, von Willebrand factor, factor VIII and white blood cell count) appear to be associated with reduced brain volume (thought to be neurodegenerative “shrinkage”) … Continue reading →

Posted in For Doctors (mostly), For Nurses and Therapists (mostly), For Researchers (mostly), In the News, International, NHS Choices, Quick Insights, Universal Interest | Tagged AD Signature Region Volume (Shrinkage), Albumin, ARIC Study: Atherosclerosis Risk in Communities, Atherosclerosis Risk in Communities (ARIC) Study, Baylor College of Medicine, Bazian, Behind the Headlines, Biomarker Development, Biomarkers, Biomarkers for Inflammation, Biomarkers Research Programmes, Blood-Based Biomarkers, Blood-Based Biomarkers of Pre-Symptomatic Alzheimer’s Disease, Brain Shrinkage, Brain Volume, Center for Cardiovascular Disease Prevention: Houston Methodist DeBakey Heart and Vascular Center, Critical Appraisals, Department of Medicine: University of Mississippi Medical Center, Departments of Neurology and Epidemiology: Johns Hopkins University School of Medicine, Departments of Neurology and Radiology: Mayo Clinic (Rochester), Division of Epidemiology and Community Health: University of Minnesota, Factor VIII, Fibrinogen, Hippocampal Volume, Hippocampal Volume (Memory Related), Hippocampus (Shrinkage in Late Adulthood), Houston Methodist DeBakey Heart and Vascular Center (Texas), Immune System, Immune System and Neurodegenerative Diseases, Inflammation, Inflammation and Neurodegenerative Diseases, Inflammatory Response, Johns Hopkins University School of Medicine, Mayo Clinic, Mayo Clinic: Rochester, Neurodegenerative Disease Research, Neurodegenerative Diseases, Neurodegenerative Disorders, Neurology (Journal), Occipital Lobe Volume (Shrinkage), Plasma Biomarkers, Preclinical Biomarkers and Dementia, Preclinical Biomarkers in Alzheimer's Disease, School of Public Health: University of Minnesota, Section of Cardiology: Baylor College of Medicine, Section of Cardiology: Baylor College of Medicine. Baylor College of Medicine, Systemic Inflammation, Systemic Inflammation and Neurodegeneration, United States, University of Minnesota, University of Mississippi Medical Center, University of Mississippi Medical Centre, US National Heart Lung and Blood Institute, USA, von Willebrand Factor, White Blood Cell Count | Leave a comment

Research Towards a World Without Dementia: Marking World Alzheimer’s Day / World Alzheimer’s Month 2017 (Alzheimer’s Disease International / Department of Health)

Posted on September 23, 2017 by Dementia and Elderly Care News

Summary Information is available from Alzheimer’s Disease International (ADI) concerning World Alzheimer’s Month (September) and World Alzheimer’s Day 2017, which was on September 21st 2017. The theme for this year’s World Alzheimer’s Month campaign is again “Remember Me”. The UK … Continue reading →

Posted in Charitable Bodies, Commissioning, Department of Health, Diagnosis, In the News, Integrated Care, International, Management of Condition, Mental Health, Models of Dementia Care, National, NHS, Non-Pharmacological Treatments, Person-Centred Care, Pharmacological Treatments, Quick Insights, Standards, UK, Universal Interest | Tagged 70th World Health Assembly Adopted Global Action Plan on Dementia, Ageing Population, Awareness, Awareness Campaigns, Awareness Raising, Carey Mulligan, Carey Mulligan: UK Global Dementia Friends Ambassador, Collaborative Research, Collaborative Working, Community and Voluntary Sector, Dementia Awareness Campaigns, Dementia Awareness Raising, Dementia Friends, Dementia Friends Programme, Dementia Research, Dementia Research Institute (DRI), Dementia-Friendly Communities, Dementia-Friendly Environments, Dementia-Friendly Organisations, Disease-Modifying Therapies, Disease-Modifying Therapies for Dementia, Drug Discovery Programmes, First G8 Dementia Summit, G8 Dementia Summit, G8 Dementia Summit Declaration, G8 Dementia Summit: Global Action Against Dementia, Global Action Against Dementia, Global Action Plan on Dementia, Global Alzheimer’s and Dementia Action Alliance, Global Alzheimer’s and Dementia Action Alliance (GADAA), Global Context, Global Dementia Friends Ambassadors, Global Leadership, Health Secretary Jeremy Hunt, International Collaborations, International Dementia Research, Leadership for Compassionate Care, Neurodegenerative Disease Research, Neurodegenerative Diseases, Neurodegenerative Disorders, Neurodegenerative Research, Partnership Working, Reducing Stigma, Research and Development, Research and Innovation, Research Commitment, Rt Hon Jeremy Hunt MP: Secretary of State for Health, Stigma of Dementia, Stigma-Free Environments, UK Dementia Research Institute, UK Dementia Research Institute (UK DRI), Voluntary Organisations, WHO Global Action Plan on the Public Health Response to Dementia 2017-2025, World Alzheimer's Month 2017 (Remember Me), World Alzheimer’s Day 2017, World Alzheimer’s Month 2017, Yuichiro Miura: Japan’s Dementia Supporters Ambassador | Leave a comment

Early Research on Stress and Social Disadvantage as Potential Risk Factors (BBC News / AAIC)

Posted on July 20, 2017 by Dementia and Elderly Care News

Summary Early research findings presented at the Alzheimer’s Association International Conference in London suggest that stressful life events, and more generally the chronic stress of enduring social deprivation life-long, may age the brain. The researchers claim that extremely stressful experiences … Continue reading →

Posted in BBC News, Charitable Bodies, Community Care, For Nurses and Therapists (mostly), For Researchers (mostly), For Social Workers (mostly), In the News, International, Quick Insights, UK, Universal Interest | Tagged 2017 Alzheimer’s Association International Conference (AAIC®2017), African Americans, Alzheimer’s Association AAIC Press Office, Alzheimer’s Association International Conference (AAIC®2017), Dementia Risk Factors, Dementia Risk Prevention, Dementia Risk Reduction, Dementia Risk Reduction and Prevention, Environmental Risk Factors, Epidemiology, Epidemiology and Statistics, Ethnicity, Health Determinants, Health Improvement, Health Inequalities, Health Policy, Immune System, Immune System and Neurodegenerative Diseases, Improving Local Public Health, Improving Public Health, Inflammation, Inflammation and Neurodegenerative Diseases, Inflammatory Response, Lifestyle Risk Factors, Modifiable Risk Factors, Necroptosis, Neurodegenerative Disease Research, Neurodegenerative Diseases, Neurodegenerative Disorders, Neuroinflammation, Overlapping Risk Factors, Potentially Modifiable Socio-Environmental Risk Factors, Prevention, Prevention Agenda, Prevention of Dementia, Reducing Health Inequalities, Risk Factors, Social Epidemiology, Socio-Environmental Risk Factors, Stressful Life Experiences, University of Wisconsin School of Medicine, University of Wisconsin-Milwaukee | Leave a comment

Tag Archives: Neurodegenerative Disorders

Preventative Treatment to Reduce Risk of Alzheimer’s Disease, Using Non-Steroidal Anti-Inflammatory Drugs? (NHS Choices / Journal of Alzheimer’s Disease)

Dementia Researchers Recognised and Rewarded (BBC News / Lundbeck Foundation)

The Most Significant Breakthrough in the Treatment of Neurodegenerative Diseases in Fifty Years? (BBC News / UCL)

Research Towards a World Without Dementia: Marking World Alzheimer’s Day / World Alzheimer’s Month 2017 (Alzheimer’s Disease International / Department of Health)

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