Tag Archives: Neuroimaging Tools

Limited Usefulness of MRI for Improving the Prediction of Dementia? (BMJ)

Summary Research indicates that MRI does not significantly improve the prediction of dementia. It does have some value in differential diagnosis. Full Text Link Reference Stephan, BC. Tzourio, C. [and] Auriacombe, S. [et al] (2015). Usefulness of data from magnetic … Continue reading

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Glasgow Coma Scale Update (Nursing Times / BBC News / PLoS Computational Biology / Nature Communications)

Summary The Glasgow Coma Scale has been updated forty years after its initial implementation. This Nursing Times article reviews the variations in technique which have developed since then, the scale’s current composition and application and the “structured approach” to the … Continue reading

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UK Biobank: Ambitious Imaging Data Collection (BBC News / European Psychiatry)

Summary Around 100,000 of the 500,000 adults aged 40-69 and currently enrolled in UK Biobank are to be invited to take part in detailed imaging of their brain, heart and other major organs. This will be the world’s biggest scanning … Continue reading

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Alzheimer’s Disease Biomarkers: Updated Hypothetical Model (Lancet Neurology)

Summary A hypothetical model of the major biomarkers of Alzheimer’s Disease, published by the same authors in 2010, has been updated in the light of new evidence. Full Text Link Reference Jack, CR. Jr. Knopman, DS. [and] Jagust, WJ. [et … Continue reading

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Appropriate Use of Neuroimaging in Dementia Diagnosis (Ontario Health Technology Assessment Series / BBC News)

Summary This economic literature review and cost-effectiveness analysis investigated neuroimaging for diagnostic purposes, and in particular examined whether computed tomography (CT) or magnetic resonance imaging (MRI) should be used. It was not possible to answer the specific research questions with … Continue reading

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Biomarker Assessments in Alzheimer’s Disease Clinical Trials (Quintiles / Frontiers in Aging Neuroscience)

Summary Accurate and sensitive tools are required for the early detection / diagnosis of Alzheimer’s Disease, particularly to assist research. Alzheimer’s Disease clinical trials make increasing use of biomarkers, particularly neuroimaging markers and cerebrospinal fluid (CSF) biomarkers obtained via invasive … Continue reading

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Brain Scans for Alzheimer’s Disease Detect tau Protein (BBC News)

Summary Innovative brain imaging techniques, which are understood to be better at detecting the build-up of tau protein (linked to Alzheimer’s Disease), have been developed by Japanese scientists. Read more: BBC News: Alzheimer’s brain scan detects tau protein. Reference Gallagher, J. (2013). Alzheimer’s brain scan detects tau protein. … Continue reading

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Computerised Cognitive Testing: Cutting Delays in Dementia Assessments (Cambridge Cognition and IXICO)

Summary Cambridge Cognition (a leading British developer of neuropsychological tests) and IXICO (a leading brain imaging specialist), have developed tools which promise to assist in achieving more accurate and rapid dementia assessments. Their innovations consist of (i) the Dementia Friendly GP … Continue reading

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Neuroimaging for Early Diagnosis of Neurodegenerative Disease

Summary The roles of magnetic resonance and radionuclide imaging in the early diagnosis and pre-clinical detection of dementia and parkinsonism are reviewed. Structural imaging has traditionally been used to exclude alternate diagnoses, but recent advances in magnetic resonance and multimodal … Continue reading

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PET in Dementia Diagnosis and Treatment (Applied Radiology)

[A brief reference to this item appears in: Dementia and Elderly Care: the Latest Evidence Newsletter (RWHT), Volume 3 Issue 3, October 2012]. Summary The role of PET in the diagnosis and management of dementia is ex­pected to increase in … Continue reading

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