Tag Archives: Neuroleptics

Pharmacological Treatment of Agitation in Persons With Dementia (British Journal of Clinical Pharmacology)

Posted on April 17, 2018 by Dementia and Elderly Care News

Summary A systematic review and meta‐analysis of pharmaceutical treatments for alleviating agitation in dementia has been performed. Regarding the efficacy and treatment acceptability of these medications, it is reported that: “Risperidone, SSRIs as a class and Dextromethorphan / Quinidine demonstrated … Continue reading →

Review of Non-Pharmacological Interventions for Dementia-Related Agitation: Including a Brief Analysis of the Risks and Benefits of Drug Treatments (Translational Psychiatry)

Posted on October 31, 2017 by Dementia and Elderly Care News

Summary A recently published literature review evaluates the best available evidence on the effectiveness of various non-pharmacological interventions for reducing dementia-related agitation. The author also briefly addresses current viewpoints on balancing the risks and benefits of pharmacotherapy in the management … Continue reading →

Posted in Acute Hospitals, Antipsychotics, For Carers (mostly), For Doctors (mostly), For Nurses and Therapists (mostly), For Researchers (mostly), Local Interest, Management of Condition, Mental Health, Models of Dementia Care, New Cross Hospital, Non-Pharmacological Treatments, Person-Centred Care, Personalisation, Pharmacological Treatments, Quick Insights, Royal Wolverhampton NHS Trust, Royal Wolverhampton NHS Trust Authorial Affiliation, Systematic Reviews, UK, Universal Interest, Wolverhampton | Tagged ACADIA Pharmaceuticals, Agitation, Agitation and Aggression, Alternatives to Antipsychotic Drugs, Animal Assisted Therapy, Antipsychotics, Antipsychotics and Risk of Venous Thromboembolism, Antipsychotics in Elderly People with Dementia, Antipsychotics Limitation in Dementia, Antipsychotics-Related Mortality Risks, Aromatherapy, Arts and Music in Dementia, Atypical Antipsychotics, Avanir Pharmaceuticals Inc (California), Behavioural Alternatives to Antipsychotic Drugs, Behavioural and Psychological Symptoms of Dementia (BPSD), Behavioural Problems, Behavioural Problems in People With Dementia, Behavioural Variant Frontotemporal Dementia (bvFTD), BPSD, BPSD: Behavioral and Psychological Symptoms of Dementia, Carbamazepine, Citalopram, Citalopram for Agitation in Alzheimer's Disease: CitAD Trial, Cognitive Behavioral Therapy, Dementia-Related Agitation, Department of Medicine: Royal Wolverhampton NHS Trust, Describe Investigate Create and Evaluate (DICE) Approach, East Kent Hospitals University NHS Foundation Trust, Electroconvulsive Therapy for Agitation and Aggression in Dementia, Improving the Quality of Life for People With Dementia, Interventions for BPSD, Intra-Cellular Therapies, Medication-Related Risks, Medications: Best Usage, Medicines Optimisation, Memantine, Mirtazapine, Mood Disturbances, Multisensory Stimulation, Music Therapy, Music Therapy for BPSD, Music-Based Therapeutic Interventions, Nature Publishing Group, Neuroleptic Discontinuation, Neuroleptics, Neuropsychiatric Symptoms (NPS), Neuropsychiatric Symptoms in People With Dementia, Non-Pharmacological Management of Symptoms, Non-Pharmacological Treatments, Otsuka Pharmaceuticals Limited, Pharmacological Treatments, Potential Harms of Antipsychotic Use, Potentially Inappropriate Medications (PIM), Potentially Inappropriate Prescribing (PIP), Potentially Inappropriate Prescribing in Advanced Dementia, Prescribing of Antipsychotic Drugs For People With Dementia, Quetiapine, Reducing Inappropriate Use of Antipsychotics in Dementia, Risperidone, Simulated Presence Therapy (SPT), Simulated Presence Therapy for BPSD, Targeted Interdisciplinary Model for Evaluation and Treatment of Neuropsychiatric Symptoms (TIME), Translational Psychiatry, Withdrawal of Neuroleptic Medications | Leave a comment

Historic Reduction in the Use of Antipsychotics for BPSD in UK General Practice? (Drug Safety)

Posted on August 23, 2017 by Dementia and Elderly Care News

Summary Data from 111,346 patients with dementia but without a concomitant diagnosis of psychosis indicates that prescribing of certain categories of antipsychotic drugs did reduce from 8.9% in 2001 to 1.4% in 2014. At face value, this reduction in inappropriate … Continue reading →

Immovable Antipsychotic Prescribing Practices in Care Homes? (BMJ Open)

Posted on September 23, 2016 by Dementia and Elderly Care News

Summary Incredible as it may seem, and contrary to years of high-level campaigning plus the circulation of awareness raising reports and guidelines, antipsychotic prescribing in long-term residential care in England did not, in fact, decline measurably during the four years … Continue reading →

Posted in Antipsychotics, Commissioning, Community Care, For Carers (mostly), For Doctors (mostly), For Nurses and Therapists (mostly), For Researchers (mostly), For Social Workers (mostly), In the News, International, Management of Condition, Mental Health, Models of Dementia Care, Pharmacological Treatments, Quick Insights, Standards, Statistics, UK, Universal Interest | Tagged Alternatives to Antipsychotic Drugs, Alternatives to Antipsychotic Medication, Antipsychotic Drugs, Antipsychotic Prescribing in Care Homes, Antipsychotics, Antipsychotics and Risk of Venous Thromboembolism, Antipsychotics in Elderly People with Dementia, Antipsychotics Limitation in Dementia, Antipsychotics-Related Mortality Risks, Atypical Antipsychotics, Avoidable Harm, Avoidable Mortality, Behavioural and Psychological Symptoms of Dementia (BPSD), BMJ Open, BMJ Publishing Group Ltd, BPSD, BPSD: Behavioral and Psychological Symptoms of Dementia, City University London, Coventry, Coventry University, Department Mathematics and Statistics: Lancaster University, Discontinuation of Antipsychotics, English National Dementia Strategy, Faculty of Health and Life Sciences: Coventry University, Inappropriate Use of Antipsychotics in Dementia, Institute for Employment Research: University of Warwick, Invatech Health Ltd, Lancaster, Lancaster University, Management of Medicines, National Dementia Strategy, Neuroleptic Discontinuation, Neuroleptics, Norwich Medical School: University of East Anglia, Potential Harms of Antipsychotic Use, Prescribing of Antipsychotic Drugs For People With Dementia, Psychological Symptoms of Dementia (BPSD), Qualitative Research, Reducing Antipsychotic Prescriptions in Dementia, Reducing Inappropriate Use of Antipsychotics in Dementia, School of Health Sciences: City University London, University of East Anglia, University of Warwick, Withdrawal of Neuroleptic Medications | 1 Comment

Reducing Antipsychotic Prescribing for BPSD (BMJ / JAMA / JAMA Psychiatry / BJCP)

Posted on November 6, 2014 by Dementia and Elderly Care News

Summary This BMJ “Change page” article discusses the potential harms associated with use of antipsychotics in people with dementia, and covers guidelines recommending restrictions in their use. Risperidone is the antipsychotic recommended for use in the treatment of aggression associated … Continue reading →

Posted in Acute Hospitals, Antipsychotics, Community Care, For Doctors (mostly), For Nurses and Therapists (mostly), For Researchers (mostly), International, Management of Condition, Mental Health, Models of Dementia Care, Non-Pharmacological Treatments, Person-Centred Care, Pharmacological Treatments, Practical Advice, Quick Insights, Standards, Statistics, UK | Tagged Adverse Drug Reactions (ADRs), Adverse Drug Reactions (ADRs): Type A (Potentially Avoidable and Associated With Commonly Prescribed Medications), Adverse Drug Reactions in the Elderly, Adverse Effects, Aggression, Aggressive Behaviour, Alternatives to Antipsychotics, Antidepressants, Antihypertensives, Antipsychotic Drugs, Antipsychotics, Antipsychotics and Risk of Venous Thromboembolism, Antipsychotics Limitation in Dementia, Antipsychotics Side Effects, Antipsychotics-Related Mortality Risks, Antipsychotics: Absolute Mortality Risk Increase, Antipsychotics: Neuroleptic Sensitivity, Antipsychotics: Number Needed to Harm (NNH), Atypical Antipsychotics, Behavioural and Psychological Symptoms of Dementia (BPSD), Benzodiazepines, BMJ, BPSD, BPSD: Behavioral and Psychological Symptoms of Dementia, Brief Psychosocial Treatment, British Journal of Clinical Pharmacology, British Medical Journal (BMJ), Campbell Institute (CAMH): University of Toronto, Cardiff University, Center for Clinical Management Research: Veterans Affairs Ann Arbor Healthcare System (Michigan), Center for Statistical Consultation and Research: University of Michigan, CitAD Research Group, Citalopram for Agitation in Alzheimer's Disease: CitAD Trial, Clinical Biotechnology Research Institute: Roper St Francis Healthcare (Charleston: South Carolina), College of Physicians and Surgeons of Columbia University, DART-AD: Dementia Antipsychotic Withdrawal Trial (DART-AD), Dementia Antipsychotic Withdrawal Trial (DART-AD), Department of Psychiatry: University of Michigan, Department of Psychiatry: University of Southern California, Discontinuation of Antipsychotics, Effect of Citalopram on Agitation in Alzheimer Disease (CitAD Randomized Clinical Trial), Falls Prevention, Hotchkiss Brain Institute: University of Calgary, Inappropriate Prescribing, Inappropriate Use of Antipsychotics in Dementia, International Conference on Harmonization, JAMA, JAMA Psychiatry, Johns Hopkins Bayview and Johns Hopkins School of Medicine, Johns Hopkins Bloomberg School of Public Health: Baltimore, Kings College London, Medication Reviews, National Institute for Health Research (NIHR): Mental Health Biomedical Research Centre and Dementia Unit, NEST Approach, Neuroleptic Discontinuation, Neuroleptics, New York State Psychiatric Institute, Patients’ Needs and the Environment Stimulation and Techniques (NEST), Perelman School of Medicine: University of Pennsylvania, Personalised Social Interaction, Pharmacokinetics, Polypharmacy, Potential Harms of Antipsychotic Use, Prescribing Anti-Psychotic Drugs to People with Dementia, Reducing Agitation and Distress, Reducing Antipsychotic Medication in Care Homes, Reducing Antipsychotic Prescriptions in Dementia, Reducing Inappropriate Use of Antipsychotics in Dementia, Reducing Violence and Aggression, Risperidone, Seattle Protocols, Simulated Presence Therapy, South London and Maudsley NHS Foundation Trust, Stanford University School of Medicine, United States, University Hospital Llandough (Cardiff), University of Calgary, University of Manchester, University of Michigan, University of Pennsylvania, University of Rochester School of Medicine and Dentistry, University of Southern California, University of Southern California Keck School of Medicine, University of Toronto, Violence and Aggression, Wolfson Centre for Age-Related Diseases: King’s College London | Leave a comment

Discontinuation of Antipsychotics in Patients with Dementia (Dementia and Geriatric Cognitive Disorders)

Posted on January 3, 2014 by Dementia and Elderly Care News

Summary The authors performed a systematic review and meta-analysis of randomised controlled studies comparing the outcomes of antipsychotics discontinuation (versus their continuation) in people with dementia. Changes to the severity of behavioural and psychological symptoms of dementia (BPSD) was the … Continue reading →

Neuroleptic, Sedative and Analgesic Prescription in Dementia Patients Admitted into an Acute Hospital (Royal Wolverhampton NHS Trust / Nursing Standard / YouTube)

Posted on November 8, 2012 by Dementia and Elderly Care News

Summary The aim of the research reported in this conference poster presentation was to assess the use of neuroleptics, sedatives and analgesics in patients with dementia at the Royal Wolverhampton NHS Trust. Drug charts of 51 patients were examined to … Continue reading →

Posted in Acute Hospitals, For Doctors (mostly), For Nurses and Therapists (mostly), International, Local Interest, Management of Condition, Models of Dementia Care, New Cross Dementia Project, New Cross Hospital, NHS, Pain, Pharmacological Treatments, Practical Advice, Quick Insights, Royal Wolverhampton NHS Trust, Royal Wolverhampton NHS Trust Authorial Affiliation, UK, Wolverhampton | Tagged American Geriatric Society Conference (Arizona) October 2012, American Geriatrics Society, Antipsychotic Drugs, Antipsychotics, Antipsychotics and Risk of Venous Thromboembolism, Antipsychotics in Elderly People with Dementia, Antipsychotics-Related Mortality Risks, Arizona Geriatrics Society (AzGS), Behavioral and Psychological Symptoms of Dementia (BPSD), BPSD, BPSD: Behavioral and Psychological Symptoms of Dementia, Call to Action on Antipsychotic Drugs (Dementia Action Alliance), Dementia Action Week, Dementia Action Week (2018), Differemtial Antipsychotic-Related Mortality Risks, Neuroleptics, OUCH! Campain: Observe Understand Communicate and Help, OUCH! Mnemonic, Pain Control and Dementia in the Acute Hospital, Pain Management, Pain Relief, Painkillers, Prescribing of Antipsychotic Drugs For People With Dementia, Treatment of Pain to Reduce Behavioural Disturbances, Untreated Pain, YouTube | Leave a comment

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