Tag Archives: Neuropsychiatric Inventory (NPI)

Young Blood Infusion Recapitulates Folklore: Vampire Therapy for Dementia? (Telegraph / CTAD / JPAD)

Summary A small trial to check the safety and tolerability of youthful blood infusions for the treatment or amelioration of Alzheimer’s Disease has detected early signs of improvement in activities of daily living. Randomly selected individuals from just 18 over-65 … Continue reading

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Pharmacological Treatment for Agitation in Alzheimer’s Disease? (JAMA)

Summary Combination dextromethorphan-quinidine shows early signs of being a safe and effective treatment option for Alzheimer’s Disease-related agitation. Full Text Link Reference Cummings, JL. Lyketsos, CG. [and] Peskind, ER. [et al] (2015). Effect of dextromethorphan-quinidine on agitation in patients with … Continue reading

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Latrepirdine for Alzheimer’s Disease: Systematic Review (Cochrane Database of Systematic Reviews)

Summary This systematic review investigated the potential of Latrepirdine as a disease-modifying intervention for Alzheimer’s Disease. The evidence suggests, so far, that Latrepirdine has no beneficial effect on cognition and / or function in patients. The authors of this review … Continue reading

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The CAREDEM Case Management Modelling and Feasibility Study (HTA)

Summary The CAREDEM Case Management Study adapted a promising case management project from the USA (the PREVENT Study) and attempted to test the feasibility and acceptability of this approach to case management for dementia support in English general practice. The … Continue reading

Posted in Commissioning, Community Care, For Doctors (mostly), For Nurses and Therapists (mostly), For Researchers (mostly), For Social Workers (mostly), Integrated Care, International, Management of Condition, Models of Dementia Care, NIHR, Non-Pharmacological Treatments, Patient Care Pathway, Person-Centred Care, Personalisation, Quick Insights, Systematic Reviews, UK | Tagged , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , | Leave a comment

Statins for the Treatment of Vascular Dementia or Alzheimer’s Disease (Cochrane Database)

Summary This Cochrane systematic review assesses the clinical efficacy and safety of statins for the treatment of Alzheimer’s Disease and vascular dementia. No studies exist yet assessing role of statins in treatment of vascular dementia. Analysis of four studies concerning … Continue reading

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Pharmacological Treatments for Neuropsychiatric Symptoms in Alzheimer’s Disease (Journal of Neurology Neurosurgery and Psychiatry)

Summary This systematic review investigates the efficacy and safety of various pharmacological treatments for neuropsychiatric symptoms in Alzheimer’s Disease patients. It concludes that cholinesterase inhibitors (ChEIs) and atypical antipsychotics could improve neuropsychiatric symptoms in these patients, but with poor patient … Continue reading

Posted in Antipsychotics, Depression, For Doctors (mostly), For Researchers (mostly), International, Management of Condition, Mental Health, Models of Dementia Care, Pharmacological Treatments, Systematic Reviews | Tagged , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , | Leave a comment

Individual Cognitive Stimulation Therapy for Dementia (iCST): RCT Study Protocol (Trials)

Summary Although the Department of Health favours improving access to psychological therapies many people with dementia are unable to access psychological interventions which could improve their quality of life, and that of their carers. Cognitive Stimulation Therapy (CST) groups can improve … Continue reading

Posted in Community Care, For Carers (mostly), For Nurses and Therapists (mostly), For Researchers (mostly), For Social Workers (mostly), Management of Condition, Mental Health, Models of Dementia Care, Non-Pharmacological Treatments, Patient Care Pathway, Person-Centred Care, Practical Advice, Quick Insights, UK, Universal Interest | Tagged , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , | Leave a comment

Dementia with Lewy Bodies and Alzheimer’s Disease: Comparison of Cognitive Decline Cohort Study (UCL)

Summary Dementia with Lewy Bodies (DLB) accounts for 10%-15% of dementia cases and has distinct clinical features associated with earlier institutionalisation and a higher level of carer distress than in Alzheimer’s disease (AD). Understanding more about the rate of decline of cognitive … Continue reading

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