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Recent Posts
- Dementia-Friendly Communities Provision, Viewed as a Social Determinant of Health (JGCR / NHS England / WHO)
- International Perspectives on the Possible Impact of the COVID-19 Pandemic and Lockdown on Abuse of the Elderly (JGCR / American Journal of Geriatric Psychiatry / JAGS)
- Updates Relating to the Lancet Commission on Dementia Prevention, Intervention, and Care (Lancet / Alzheimer’s Research and Therapy / Alzheimer’s and Dementia)
- A Brief Review of How the COVID-19 Pandemic Relates to Elderly Care and Research (JGCR)
- Some Speculated / Potential Benefits of COVID-19 (JGCR / BBC Radio 4’s Rethink / BGS)
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Tag Archives: New England Journal of Medicine
Football and Dementia Risk: Mortality From Neurodegenerative Disease Higher in Former Professional Soccer Players (BBC News / Drake Foundation / NEJM / Bazian)
Summary The Football’s InfluencE on Lifelong health and Dementia risk (FIELD) study, based at Glasgow University and supported by The Football Association and The Professional Footballers’ Association, found that former Scottish professional football players tend to be over 3.5 times more … Continue reading
Posted in BBC News, For Carers (mostly), For Doctors (mostly), For Nurses and Therapists (mostly), For Researchers (mostly), In the News, National, NHS Digital (Previously NHS Choices), Parkinson's Disease, Quick Insights, Scotland, Statistics, UK, Universal Interest
Tagged Alan Shearer, Bazian, BBC Health News, BBC News Hampshire and Isle of Wight, BBC Sport, Behind the Headlines, Chronic Traumatic Encephalopathy (CTE), Concussion Action Programme, Dementia in Retired Association Football (Soccer) Players, Dementia Risk Factors, Dementia Risk Prevention, Dementia Risk Reduction, Department of Neuropathology: Queen Elizabeth University Hospital (Glasgow), Drake Foundation, Epidemiology, Epidemiology and Statistics, Football Association, Football Association (FA), Football Brain Injury Research, Football Headers, Football’s InfluencE on Lifelong health and Dementia risk (FIELD) Study, Former Professional Soccer Players, Giffnock Soccer Centre, Glasgow Brain Injury Research Group, Glasgow University, Hampden Sports Clinic: Hampden Stadium (Glasgow), Heading Footballs Associated With Dementia / CTE: a New Category of Industrial Injury?, Heading Heavy Leather Footballs, HEADING Study (Health and Ageing Data IN the Game of football), Heading the Ball, Inside Out South (BBC), Institute of Cardiovascular and Medical Sciences: University of Glasgow, Institute of Health and Wellbeing: University of Glasgow, Institute of Neuroscience and Psychology: University of Glasgow, Iwan Roberts: Former Wales and Norwich City Footballer, Lifestyle Risk Factors, Modifiable Risk Factors, Neurodegenerative Disease Mortality in Former Professional Soccer Players, Neurodegenerative Disorders, Neurodegenerative Research, Neuropathology, New England Journal of Medicine, Norwich City, Professional Footballers, Professional Footballers' Association (PFA), Queen Elizabeth University Hospital (Glasgow), Repetitive Mild Traumatic Brain Injury (rTBI), Retired Soccer Players With Dementia, SCORES Project, SCORES Study: Screening Cognitive Outcomes After REpetitive Head Impact in Sport, Scottish Football Association, Scottish Football Association (Proposed Ban on Under-12s Heading Balls in Football Training), Soccer Heading, Sports Medicine, Sub-Concussive Head Impacts, Traumatic Brain Injury, University of East Anglia (UEA), University of East Anglia (UEA) Health and Social Care Partners, University of Glasgow
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A Question of Height: a New Dimension in Statistical and Genetic Risk Factors? (BBC News / NHS Choices / British Journal of Psychiatry / NEJM)
Summary A number of studies point to the unexpected potential influence of physical height in the risks of developing various diseases (which may or may not be related). It was found last year that decreasing height is associated statistically with … Continue reading
Posted in BBC News, For Doctors (mostly), For Nurses and Therapists (mostly), For Researchers (mostly), In the News, International, NHS Digital (Previously NHS Choices), Quick Insights, Scotland, Statistics, UK, Universal Interest
Tagged Adult Height, Alzheimer Scotland Dementia Research Centre: University of Edinburgh, Atherosclerosis, Atherosclerosis (Hardening of the Arteries), Australia, BBC Health News, Behind the Headlines, British Heart Foundation, British Journal of Psychiatry, Cancer, Cancer Risk Factors, Centre for Cognitive Ageing and Cognitive Epidemiology: University of Edinburgh, Charles Perkins Centre and Exercise and Sport Sciences: University of Sydney, Coronary Artery Disease, Coronary Artery Disease (CAD), Coronary Heart Disease (CHD), Department of Epidemiology and Public Health (University College London), Division of Psychiatry: University of Edinburgh; Department of Epidemiology and Public Health: University College London, Epidemiology, Epidemiology and Statistics, ESPE: European Society for Paediatric Endocrinology, European Society for Paediatric Endocrinology Conference (2015), Genetic Risk Factors, Genetically Determined Height, Genetically Determined Height and Coronary Artery Disease, Health Survey for England, Health Survey for England (HSE), Height, Height and Cancer Risk, Height and Dementia Death, Karolinska Institute in Stockholm, Karolinska Institutet, Leducq Foundation, National Health Service (NHS) Scotland, National Institute for Health Research (NIHR), New England Journal of Medicine, Overlapping Risk Factors, Risk Factors, Risk of Coronary Artery Disease, Scottish Dementia Clinical Research Network, Scottish Health Survey, Short Stature and Dementia, Skin Cancer, Stature, Sweden, Sweden. Epidemiology, University College London, University of Cambridge, University of Edinburgh, University of Leicester, University of Sydney
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Malignant Melanoma: Increasing Incidence of Skin Cancer in the UK (BBC News / CRUK)
Summary It is estimated that 5,700 over-65s are diagnosed with malignant melanoma each year, compared to 600 in the mid-1970s. The over-65s were the first generation to “benefit” from cheaper foreign holidays and suntan salons. Risks of developing this condition … Continue reading
Posted in BBC News, Charitable Bodies, In the News, Practical Advice, Quick Insights, Statistics, UK, Universal Interest
Tagged ABCDE Checklist, Advanced Melanoma: Improving Survival Rates, Aix-Marseille University, Arm Mole Count: Skin Cancer Risk, Awareness and Campaigns, Awareness and Understanding, Awareness Raising, Baby-Boomer Generation, BBC Health News, Bristol-Myers Squibb, British Association of Dermatologists (BAD), Cancer Research UK, Cancer Research UK (CRUK), Combination Immunotherapy, Combination Nivolumab Plus Ipilimumab, Cross Cancer Institute (Canada) Maria Sklodowska-Curie Memorial Cancer Center and Institute of Oncology, CRUK: Cancer Research UK, CTLA-4, Dana-Farber Cancer Institute (Boston), Department of Medical Oncology: Royal Marsden Hospital, Drug Side-Effects, Epidemiology, Epidemiology and Statistics, European Cancer Congress (2016), European Institute of Oncology, European Society for Medical Oncology, Gill Nuttall: Melanoma UK, Hôpital de La Timone, Healthy Lifestyles, Hospital General Universitario Gregorio Marañón (Madrid), Immunotherapy, Immunotherapy Drugs, Incidence of Malignant Melanoma, Ipilimumab, Istituto Nazionale Tumori Fondazione Pascale, Lifestyle, Lifestyle Advice, Lifestyle Factors, Lifestyle Risk Factors, Malignant Melanoma, Melanoma Institute Australia, Memorial Sloan Kettering Cancer Center, Merck, Netherlands Cancer Institute, New England Journal of Medicine, Nivolumab, Odense University Hospital, Package Holiday Boom, PD-1, Pembrolizumab, Peter MacCallum Cancer Centre and University of Melbourne, Prof Carole Longson: National Institute for Health and Care Excellence (NICE), Public Health, Risk Factors for Malignant Melanoma, Royal Marsden Hospital, Sammons Cancer Center (Dallas); University of Michigan, Singleton Hospital (Swansea), Skin Cancer, Skin Cancer Statistics, Smilow Cancer Hospital of the Yale-New Haven Hospital, South West Wales Cancer Institute, Sunburn, Tasman Oncology Research: Southport Gold Coast, Unhealthy Lifestyles, United Kingdom and Ireland Association of Cancer Registries, University Hospital of Siena, University of Colorado, University of Essen, University of Sydney, University of Utah, University of Zürich Hospital, Unresectable Stage III or IV Melanoma, Untreated Melanoma, Veneto Region Oncology Research Institute, Weill Cornell Medical College, Yale Cancer Center, Yale University School of Medicine
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Bapineuzumab Trials Results in Mild-to-Moderate Alzheimer’s Disease (New England Journal of Medicine)
Summary Bapineuzumab is an anti-amyloid-beta monoclonal antibody, which had shown promise for the treatment of Alzheimer’s Disease. Two double-blind, randomised, placebo-controlled, phase 3 trials have been conducted, involving 2204 patients with mild-to-moderate Alzheimer’s disease. One trial involved 1121 carriers of … Continue reading
Posted in For Doctors (mostly), For Researchers (mostly), International, Pharmacological Treatments
Tagged Alzheimer's Disease Assessment Scale (ADAS-Cog11), Amyloid, Amyloid Beta, Amyloid Beta Protein, Amyloid Proteins, Amyloid-β (Aβ), Amyloid-β (Aβ) Accumulation, Apolipoprotein E, Apolipoprotein E (APOE) e4 Allele, Apolipoprotein E (APOE) Gene, Bapineuzumab 301, Bapineuzumab 302, Bapineuzumab for Mild-to-Moderate Alzheimer's Disease, Bapineuzumab Trials, Beta-Amyloid, Beta-Amyloid Plaques, Brigham and Women's Hospital: Boston, Butler Hospital, Cerebrospinal Fluid Phosphorylated Tau (Phospho-Tau) Concentrations, Cleo Roberts Center for Clinical Research, Clinical Trials Number NCT00574132, Clinical Trials Number NCT00575055, Columbia University, Disability Assessment for Dementia-DAD, EudraCT Number 2009-012748-17, Institute of Neurology: University College London, Janssen Alzheimer Immunotherapy and Pfizer, Janssen Alzheimer Immunotherapy Research and Development, New England Journal of Medicine, New York University Langone Medical Center, Pfizer, Pittsburgh Compound B (PIB-PET), Sahlgrenska University Hospital, Sun Health Research Institute, Sweden, University College London, University of California, University of Göteborg, University of Pittsburgh, University of Rochester School of Medicine and Dentistry, Veterans Affairs Medical Center
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Solanezumab Trials Results for Mild-to-Moderate Alzheimer’s Disease (New England Journal of Medicine)
Summary Solanezumab is a monoclonal antibody which binds soluble amyloid preferentially and had shown some promise of promoting better clearance of amyloid-beta from the brain in pre-clinical studies. Two placebo controlled trials (EXPEDITION 1 and EXPEDITION 2) of 1012 and … Continue reading
Posted in For Doctors (mostly), For Researchers (mostly), International, Pharmacological Treatments
Tagged Alzheimer's Disease and Memory Disorders Center: Baylor College of Medicine (Houston), Alzheimer's Disease Assessment Scale (ADAS-Cog11), Alzheimer's Disease Cooperative Study Steering Committee, Alzheimer's Disease Cooperative Study-Activities of Daily Living scale (ADCS-ADL), Alzheimer's Disease Cooperative Study: University of California at San Diego, Amyloid, Amyloid Beta, Amyloid Beta Protein, Amyloid Proteins, Amyloid-β (Aβ), Amyloid-β (Aβ) Accumulation, Baylor College of Medicine, Beta-Amyloid, Beta-Amyloid Plaques, Center for Human Experimental Therapeutics: University of Rochester Medical Center, Centre Hospitalier Universitaire Toulouse, Clinical Trials Number: NCT00904683, Clinical Trials Number: NCT00905372, Department of Neuropathology: University of Tokyo, Eli Lilly, Gerontopole: Unité Mixte de Recherche, Gliosis, Indiana Alzheimer Disease Center: Indiana University, Indiana University, β-amyloid, Neurofibrillary Tangles, Neuronal Loss, New England Journal of Medicine, Solanezumab for Mild-to-Moderate Alzheimer’s Disease, Solanezumab Study Group, Solanezumab Trials, Solanezumab: Humanised Monoclonal Antibody, University of California at San Diego, University of Pennsylvania, University of Rochester Medical Center
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Monetary Costs of Dementia in the United States (New England Journal of Medicine / RAND)
Summary The societal cost of dementia in the United States has been estimated to range from $157 billion to $215 billion annually according to RAND economists, making the disease more costly than heart disease or cancer. Read more: Cost of Dementia Tops $157 … Continue reading
Posted in For Researchers (mostly), In the News, International, Patient Care Pathway, Quick Insights, Statistics, Universal Interest
Tagged Age and Ageing, Ageing, Aging Demographics and Memory Study (ADAMS), Aging Parents, Alzheimer's Association, Annual Monetary Costs of Dementia in the United States, Burden of Dementia, Burden of Disease, Caregivers, Cost of Dementia (United States), Disease Burden, Economic Burden of Health Care, Geriatrics, Health and Retirement Study (HRS), Health Care Costs, HRS: Health and Retirement Study, Informant Questionnaire on Cognitive Decline in the Elderly (IQCODE), Medicare, Monetary Costs of Dementia in the United States, National Alzheimer's Project Act, National Bureau of Economic Research, National Institute on Aging, Network for Studies on Pensions Aging and Retirement, New England Journal of Medicine, Prevalence of Dementia, RAND Corporation, Social Security Administration, Telephone Interview for Cognitive Status (TICS), United States, University of Michigan, Yearly Cost per Person Attributed to Dementia
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