Tag Archives: Non-Invasive Biomarkers

Smell Test for Early Detection of Parkinson’s Disease (BBC News)

Posted on March 21, 2019 by Dementia and Elderly Care News

Summary Parkinson’s Disease has a distinctive odour for certain gifted individuals, which has been analysed chemically and may now be replicated for automated detection by machine. This may, in future, permit earlier diagnosis and open the possibilities for timely treatments … Continue reading →

Posted in BBC News, Diagnosis, For Doctors (mostly), For Nurses and Therapists (mostly), For Researchers (mostly), In the News, Parkinson's Disease, Quick Insights, Scotland, UK, Universal Interest | Tagged ACS Central Science (Journal), Anatune (Cambridge UK), BBC Health News, BBC Scotland News, Biomarkers, Biomarkers Predicting Parkinson's Disease, Department of Biochemistry: University of Liverpool, Department of Neurology: Salford Royal Foundation Trust, Early Diagnosis, Early Diagnosis of Parkinson’s Disease, Edinburgh University, Eicosane, Hyperosmic Super Smeller, Institute for Stem Cell Research: University of Edinburgh, Institute of Integrative Biology: University of Liverpool, Joy Milne, Les Milne, Manchester Academic Health Science Centre: University of Manchester, Neurodegeneration, Neurodegenerative Disease Research, Neurodegenerative Diseases, Non-Invasive Biomarkers, Odour, Parkinson's Disease Smell Test, Parkinson’s Disease Sebum Volatilome, Parkinson’s UK, Perillic Aldehyde, Rapid Screening, Salford Royal Foundation Trust, School of Biological Sciences: University of Edinburgh, Sebum, Smell Test for Parkinson's Disease Diagnosis, Timely / Preclinical Parkinson's Disease Diagnosis, Timely Diagnosis, University of Edinburgh, University of Liverpool, University of Manchester, Volatile Biomarkers of Parkinson’s Disease, Volatilome | Leave a comment

Eye Tests for Early Detection of Alzheimer’s Disease? (NHS Digital / Ophthalmology Retina)

Posted on March 20, 2019 by Dementia and Elderly Care News

Summary Further discussion about the possibilities of using inexpensive eye tests to detect Alzheimer’s Disease, perhaps years before symptoms appear. This particular technique involves the examination of blood vessels and blood flow in the retina, as detected by Octa (Optical … Continue reading →

Posted in Diagnosis, For Doctors (mostly), For Nurses and Therapists (mostly), For Researchers (mostly), In the News, International, NHS Digital (Previously NHS Choices), Quick Insights, Universal Interest | Tagged Alzheimer's Disease: Diagnosis, Alzheimer’s Disease, Alzheimer’s Disease and Dementia, Alzheimer’s Disease Biomarkers, Assessment and Diagnosis, Bazian, Behind the Headlines, Biomarkers, Biomarkers Predicting Cognitive Decline and Alzheimer's Disease, Central Subfield Thickness (CST), Cognitive Impairment, Critical Appraisals, Dementia Case Finding, Dementia Diagnosis, Dementia Screening, Diagnosis, Diagnosis of Alzheimer's Disease, Diagnostics, Duke University in North Carolina, Early Diagnosis, Early Diagnosis of Alzheimer's Disease, Early Treatment Diabetic Retinopathy Study, Eye Examinations, Foveal Avascular Zone (FAZ) Area, Karen L. Wrenn Alzheimer's Disease Award, Macular Ganglion Cell-Inner Plexiform Layer (GC-IPL), MCI: Mild Cognitive Impairment, Mild Cognitive Impairment, National Institutes of Health, National Institutes of Health (NIH), National Institutes of Health (US), Neurodegeneration, Neurodegenerative Disease Research, Neurodegenerative Diseases, NHS Digital (Formerly NHS Choices), Non-Invasive Biomarkers, Octa: Optical Coherence Tomography Angiography, Ophthalmology Retina, Optical Coherence Tomography, Optical Coherence Tomography Angiography (OCTA), Preclinical Alzheimer's Disease, Rapid Screening, Research to Prevent Blindness Inc. (New York), Retina as Early Biomarker of Neurodegeneration, Retinal Biomarkers, Retinal Examination in Neurodegenerative Diseases, Retinal Microvascular and Neurodegenerative Changes in Alzheimer’s Disease, Retinal Microvascular and Neurodegenerative Changes in Mild Cognitive Impairment, Retinal Vessel Density (VD), Screening, Screening for Dementia, Timely Diagnosis, US National Institutes of Health (NIH), USA | Leave a comment

More on Possible Blood Tests for Pre-Symptomatic Alzheimer’s Disease (NHS Digital / Nature Medicine)

Posted on January 28, 2019 by Dementia and Elderly Care News

Summary People with a rare hereditary form of Alzheimer’s Disease (Dominantly Inherited Alzheimer’s Disease) have raised levels of a protein called neurofilament light chain (NfC) in their blood, arising from damage to previously healthy nerve cells. These elevated levels of … Continue reading →

Posted in Diagnosis, For Doctors (mostly), For Nurses and Therapists (mostly), For Researchers (mostly), In the News, International, NHS Digital (Previously NHS Choices), Quick Insights, Universal Interest | Tagged APP or PSEN Mutations, Australia, Basel, Bazian, Behind the Headlines, Biomarkers, Biomarkers Predicting Cognitive Decline and Alzheimer's Disease, Blood Proteins as Biomarkers of Disease Research, Blood-Based Biomarkers, Blood-Based Biomarkers of Pre-Symptomatic Alzheimer’s Disease, Columbia University Medical Center, Dementia Research Centre, Dementia Research Centre: University College London, Department of Biomedical Sciences: Macquarie University, Department of Cellular Neurology: Hertie Institute for Clinical Brain Research, Department of Neurodegeneration: Queen Square Institute of Neurology, Department of Neurology: Columbia University Medical Center, Department of Neurology: Keck School of Medicine at USC, Department of Neurology: Ludwig-Maximilians-Universität München, Department of Neurology: Massachusetts General Hospital, Department of Neurology: Mayo Clinic Jacksonville, Department of Neurology: Washington University School of Medicine, Department of Neuroscience: Icahn School of Medicine at Mount Sinai, Department of Psychiatry and Psychotherapy: University of Tübingen, Department of Radiology: Washington University School of Medicine, Departments of Medicine Biomedicine and Clinical Research: University Hospital Basel, Division of Biostatistics: Washington University School of Medicine, Dominantly Inherited Alzheimer Network, Dominantly Inherited Alzheimer Network (DIAN), Dominantly Inherited Alzheimer's Disease, Early Diagnosis, Early Diagnosis of Alzheimer's Disease, Edith Cowan University: Western Australia, Florey Institute of Neuroscience and Mental Health: University of Melbourne, German Center for Neurodegenerative Diseases, German Center for Neurodegenerative Diseases (DZNE), Germany, Harvard Medical School, Hereditary Alzheimer's Disease, Hertie Institute for Clinical Brain Research, Icahn School of Medicine at Mount Sinai (New York), Indiana Alzheimer Disease Center and Department of Pathology and Laboratory Medicine: Indiana University School of Medicine, Indiana University School of Medicine, Ludwig-Maximilians-Universität München, Macquarie University, Macquarie University (New South Wales), Massachusetts General Hospital, National Institute on Aging, National Institute on Aging (NIA), National Institute on Aging (US), Nature Medicine, Neurodegeneration Division: The Florey Institute of Neuroscience and Mental Health, Neurodegenerative Disease Research, Neurodegenerative Diseases, Neurodegenerative Disorders, Neurofilament Light Chain (NfC), Neurofilament Light Chain (NFL), Neurofilament Light Protein (NF-L), Neurofilament Light Protein in Blood: Potential Biomarker of Neurodegeneration, Neurologic Clinic and Policlinic: University Hospital Basel, Neuroscience Research Australia, Non-Invasive Biomarkers, Plasma Biomarkers, Preclinical Alzheimer's Disease, Preclinical Biomarkers and Dementia, Preclinical Biomarkers in Alzheimer's Disease, Protein-Based Biomarkers in Blood May Deliver Accurate Diagnoses, School of Medical Health and Sciences: Edith Cowan University, School of Medical Sciences: University of New South Wales, Serum Neurofilament Light Chain Protein, Switzerland, Taub Institute for Research on Alzheimer's Disease and the Aging Brain: Columbia University Medical Center, United States, University College London, University Hospital Basel, University of Basel, University of Melbourne, University of New South Wales, University of Tübingen, US National Institute on Aging, USA, Warren Alpert Medical School of Brown University, Washington University School of Medicine | Leave a comment

Summary of Recent Progress in Alzheimer’s Disease Prevention Trials (CTAD / JPAD)

Posted on October 1, 2018 by Dementia and Elderly Care News

Summary The following article summarises a round-up of present understanding and developments reflected in current and planned prevention trials, as discussed at a EU / US / Clinical Trials in Alzheimer’s Disease (CTAD) Task Force meeting, as of December 2016-7. … Continue reading →

Screening for Dementia at the Opticians? (BBC News / NHS Choices / JAMA Neurology)

Posted on July 31, 2018 by Dementia and Elderly Care News

Summary A simple eye test, at high street opticians, for thinning of the retinal nerve fibre layer (RNFL) could in future help predict which persons are at risk of developing dementia. Full Text Link Reference Optician’s eye test ‘could spot … Continue reading →

Posted in BBC News, Diagnosis, For Doctors (mostly), For Nurses and Therapists (mostly), For Researchers (mostly), In the News, NHS Digital (Previously NHS Choices), Quick Insights, Scotland, UK, Universal Interest | Tagged Alzheimer's Disease Related Retinal Degeneration, Bazian, BBC Health News, Behind the Headlines, Biomarker Development, Biomarkers, Biomarkers Predicting Cognitive Decline and Alzheimer's Disease, Biomarkers Research Programmes, Centre for Medical Informatics: University of Edinburgh, Critical Appraisals, Dementia Screening, Dementia Screening Debate, Department of Psychiatry: University of Oxford, Early Diagnosis, Early Screening, Institute of Cognitive Neuroscience: University College London, International Glaucoma Association, JAMA Neurology, Moorfields Eye Hospital NHS Foundation Trust NHS Foundation Trust, National Institute for Health Research (NIHR), National Institute for Health Research Biomedical Research Centre, Neurodegeneration, Neurodegenerative Disease Research, Neurodegenerative Diseases, Neuronal Loss, Non-Invasive Biomarkers, Ocular Manifestations in Neurodegenerative Diseases, Ocular Manifestations of Alzheimer's Disease, Ocular Manifestations of Dementia, Ocular Manifestations of Neurodegenerative Disease, Ocular Neurodegenerative Conditions, Ocular Neurodegenerative Pathologies, Ocupharm Diagnostics SL (Madrid), Optical Coherence Tomography, Retina as Early Biomarker of Neurodegeneration, Retinal Biomarkers, Retinal Examination in Neurodegenerative Diseases, Retinal Ganglion Cell Layer, Retinal Nerve Fibre Layer (RNFL), Retinal Neuronal Loss, Retinal Thickness, Spain, Timely Diagnosis, Topcon Healthcare Solutions Research and Development, UCL Institute of Ophthalmology, UK Biobank, UK Biobank: Eye and Vision Consortium, Universidad Alfonso X (Madrid), Universidad Complutense de Madrid, University College London, University College London Institute of Ophthalmology, University of Edinburgh, University of Oxford, Usher Institute for Population Health Sciences and Informatics: University of Edinburgh, Visual System Pathological and Functional Alterations in Alzheimer’s Disease, Visual System Pathological and Functional Alterations in Dementia, Visual System Pathological and Functional Alterations in Neurological Diseases | Leave a comment

Preventative Treatment to Reduce Risk of Alzheimer’s Disease, Using Non-Steroidal Anti-Inflammatory Drugs? (NHS Choices / Journal of Alzheimer’s Disease)

Posted on March 31, 2018 by Dementia and Elderly Care News

Summary A recent article suggests that use of nonsteroidal anti-inflammatory drugs (NSAIDs) might help to reduce the risk of developing Alzheimer’s Disease, if prescription were to be commenced years before clinical signs were to develop. An NHS Choices Behind the … Continue reading →

Posted in For Doctors (mostly), For Nurses and Therapists (mostly), For Researchers (mostly), In the News, International, NHS Digital (Previously NHS Choices), Pharmacological Treatments, Quick Insights, Universal Interest | Tagged Aβ42, Alzheimer Disease Anti-Inflammatory Prevention, Alzheimer’s Disease Biomarkers, Amyloid Beta (Aβ42), Amyloid Beta Protein, Amyloid Cascade Inflammatory Hypothesis, Amyloid-β (Aβ), Amyloidogenic and Inflammatory Pathways, Aurin Biotech, Aurin Biotech Inc. Ltd. (Vancouver), ß-amyloid, Bazian, Behind the Headlines, Biomarkers, Canada, Critical Appraisals, Dementia Risk Reduction and Prevention, Dementia Saliva Testing (Pilot Study), Diagnosis of Alzheimer's Disease Based on Salivary Amyloid-β Protein 42 Levels, ELISA Method to Determine Aβ42 Levels in Saliva, Fluid Biomarker Analysis, Ibuprofen, Ibuprofen and the Reduced Risk of Alzheimer’s Disease Link, Inflammation, Journal of Alzheimer's Disease, Long-Term Ibuprofen Use, Neurodegenerative Disease Research, Neurodegenerative Diseases, Neurodegenerative Disorders, Neurodegenerative Research, Neuroinflammation, Non-Invasive Biomarkers, Non-Steroidal Anti-Inflammatory Drugs (NSAIDS), NSAIDS: Non-Steroidal Anti-Inflammatory Drugs, Preclinical Biomarkers in Alzheimer's Disease, Preventative Interventions, Prevention, Saliva Tests, Salivary Amyloid-β Protein 42 Levels, Salivary Biomarkers | Leave a comment

Blood Test for Pre-Symptomatic Alzheimer’s Disease Likely to Arrive Soon? (BBC News / Nature)

Posted on February 1, 2018 by Dementia and Elderly Care News

Summary A blood test developed by researchers in Australia and Japan appears to be able to predict the risk of developing Alzheimer’s Disease, with 90% accuracy. Detection of amyloid beta in the blood may be taken as a biomarker for … Continue reading →

Posted in BBC News, Diagnosis, For Carers (mostly), For Doctors (mostly), For Nurses and Therapists (mostly), For Researchers (mostly), In the News, International, Quick Insights, Universal Interest | Tagged Alzheimer’s Disease, Amyloid Beta, Amyloid-β (Aβ), Austin Health: Australia, Australia, ß-amyloid, BBC Health News, Beta-Amyloid, Biomarkers, Biomarkers Predicting Cognitive Decline and Alzheimer's Disease, Blood Proteins as Biomarkers of Disease Research, Blood-Based Biomarkers, Blood-Based Biomarkers of Pre-Symptomatic Alzheimer’s Disease, Center for Development of Advanced Medicine for Dementia:: National Center for Geriatrics and Gerontology (Japan), Conversion to Dementia From Prodromal Disease, CSIRO (Brisbane), Edith Cowan University: Western Australia, Florey Institute: University of Melbourne, Health and Biosecurity: CSIRO (Brisbane), Japan, Koichi Tanaka Mass Spectrometry Research Laboratory: Shimadzu Corporation, Koichi Tanaka Mass Spectrometry Research Laboratory: Shimadzu Corporation (Kyoto), Laboratory of Neuropathology and Neuroscience: University of Tokyo, National Center for Geriatrics and Gerontology (Japan), Nature, Non-Invasive Biomarkers, Plasma Amyloid-β Biomarkers for Alzheimer’s Disease, Plasma Biomarkers, Preclinical Biomarkers in Alzheimer's Disease, Protein-Based Biomarkers in Blood May Deliver Accurate Diagnoses, Shimadzu Corporation, Shimadzu Corporation (Kyoto), Tokyo Metropolitan Institute of Gerontology, University of Melbourne, University of Tokyo | Leave a comment

Tag Archives: Non-Invasive Biomarkers

Smell Test for Early Detection of Parkinson’s Disease (BBC News)

Eye Tests for Early Detection of Alzheimer’s Disease? (NHS Digital / Ophthalmology Retina)

More on Possible Blood Tests for Pre-Symptomatic Alzheimer’s Disease (NHS Digital / Nature Medicine)

Preventative Treatment to Reduce Risk of Alzheimer’s Disease, Using Non-Steroidal Anti-Inflammatory Drugs? (NHS Choices / Journal of Alzheimer’s Disease)

Blood Test for Pre-Symptomatic Alzheimer’s Disease Likely to Arrive Soon? (BBC News / Nature)

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