Tag Archives: Nuffield Department of Clinical Neurosciences: University of Oxford

Cardiovascular Health in Old Age Associated With Reduced Risk of Cognitive Decline and Dementia (NHS Choices / JAMA)

Summary Fresh evidence from France suggests that favourable cardiovascular health metrics – measured using the American Heart Association (AHA)’s Life’s Simple 7 Metrics tool – and higher cardiovascular health scores, are associated with a lower risk of developing dementia and … Continue reading

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Aspirin: Stomach Bleeds Risk for Over-75s (BBC News / Lancet / NHS Choices)

Summary Persons aged over 75 taking daily aspirin following a stroke or heart attack are at higher risk of stomach bleeds than thought previously. The benefits of low dose aspirin still outweigh the risks, even in this age group. Co-prescription … Continue reading

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Another Recent Alzheimer’s Disease Drug Trial Disappointment (Lancet)

Summary Researchers aimed to discover whether LMTM [Leuco-methylthioninium bis(hydromethanesulfonate] might be safe and effective for slowing disease progression in patients with mild to moderate Alzheimer’s Disease. LMTM had previously been found to work as a selective inhibitor of tau protein … Continue reading

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Early Diagnosis of Parkinson’s Disease and DLB Using CSF Biomarker? (BBC News / Annals of Clinical and Translational Neurology)

Summary Research at the University of Edinburgh indicates that test for synuclein, which measures how sticky this protein molecule has become (i.e. alpha-synuclein aggregation), might be the key to diagnosing accurately the early stages of both Parkinson’s Disease and Dementia … Continue reading

Posted in BBC News, Diagnosis, For Doctors (mostly), For Nurses and Therapists (mostly), For Researchers (mostly), In the News, Parkinson's Disease, Scotland, UK, Universal Interest | Tagged , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , | Leave a comment

Blood Pressure: a Risk Factor for Vascular Dementia (Alzheimer’s Society / Stroke / BHF)

Summary Researchers at the George Institute for Global Health, following 4.28 million individuals, have shown a statistical association indicating that high blood pressure in middle age significantly increases the risk of developing vascular dementia (the second most common form of … Continue reading

Posted in Alzheimer's Society, For Doctors (mostly), For Nurses and Therapists (mostly), For Researchers (mostly), Hypertension, In the News, International, Quick Insights, Statistics, Stroke, UK, Universal Interest | Tagged , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , | Leave a comment

Researchers Advise Use of Aspirin Immediately After Minor Strokes (BBC News / Lancet)

Summary The benefits of taking aspirin immediately after a mini or minor stroke, to prevent or limit harm, have been hugely under-estimated. Full Text Link Reference Mundasad, S. (2016). ‘Immediate aspirin’ advice for minor stroke.  London: BBC Health News, May … Continue reading

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Hotly Debated Weekend Effect May Have Been A Statistical Mirage? (Journal of Health Services Research and Policy / BBC News / Lancet / BMJ)

Summary Research does not take place in a socio-political vacuum. The ongoing junior doctors’ dispute has supplied fertile ground for allegations of “spin” and politically-motivated distortion in the interpretation of the so-called “weekend effect”, and raises questions concerning the planned … Continue reading

Posted in Acute Hospitals, BBC News, Commissioning, For Doctors (mostly), For Nurses and Therapists (mostly), For Researchers (mostly), In the News, Integrated Care, National, NHS, Quick Insights, Standards, Statistics, UK, Universal Interest | Tagged , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , | Leave a comment

Possible Link Between Alzheimer’s Disease and Schizophrenia? (BBC News / PNAS)

Summary A “weak spot” in the brain, which may be play some common role(s) underlying both Alzheimer’s Disease and schizophrenia, appears to have been identified using functional Magnetic Resonance Imaging (fMRI) brain scans. The brain area in question has been … Continue reading

Posted in BBC News, For Doctors (mostly), For Nurses and Therapists (mostly), For Researchers (mostly), In the News, International, Mental Health, Quick Insights, UK, Universal Interest | Tagged , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , | Leave a comment

Further Dementia Diagnostic Test Accuracy Systematic Review Protocols (Cochrane Database)

Summary This is an additional list of diagnostic testing-related protocols, further to the Cochrane Dementia and Cognitive Improvement Group (CDCIG) Diagnostic Test Accuracy (DTA) protocols and protocol templates listed earlier in Generic Protocol(s) for Diagnostic Test Accuracy Reviews in Dementia … Continue reading

Posted in Diagnosis, For Doctors (mostly), For Nurses and Therapists (mostly), For Researchers (mostly), Models of Dementia Care, NIHR, Systematic Reviews, UK | Tagged , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , | Leave a comment

Alzheimer’s Disease-Related Gray Matter Atrophy Prevention Using B-Vitamin Treatment (NHS Choices / PNAS)

Summary Researchers explored the prevention of brain atrophy in areas related to cognitive decline and Alzheimer’s disease (AD) by lowering elevated plasma homocysteine using B vitamins. An earlier study on people with increased dementia risk had indicated that high-dose B-vitamin … Continue reading

Posted in For Researchers (mostly), In the News, International, NHS Digital (Previously NHS Choices), Nutrition, Pharmacological Treatments, Quick Insights, UK, Universal Interest | Tagged , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , | Leave a comment