Tag Archives: Off-Label Drug Repurposing Trials

Animal Study Explores the Potential of a Novel Diabetes Drug for Reducing Memory Loss in Dementia – In Mice (NHS Choices / Brain Research)

Summary Early animal research indicates that a new drug designed for the future treatment of diabetes may (one day) have an alternative re-use for reducing the memory-loss symptoms of Alzheimer’s Disease. Mice given a modified version of a so-called triple … Continue reading

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Parkinson’s Disease in Adults: Updated Guidance (NICE / BBC News / NHS Choices / Lancet)

Summary The National Institute for Health and Care Excellence recently released an updated guideline on the diagnosis and management of Parkinson’s Disease in patients aged over 18 years. This guidance updates and replaces their earlier “NG35 – Parkinson’s disease in … Continue reading

Posted in BBC News, Commissioning, Diagnosis, For Doctors (mostly), For Nurses and Therapists (mostly), For Researchers (mostly), In the News, Integrated Care, International, Management of Condition, National, NHS Digital (Previously NHS Choices), NICE Guidelines, Non-Pharmacological Treatments, Parkinson's Disease, Person-Centred Care, Pharmacological Treatments, Quick Insights, Standards, UK | Tagged , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , | Leave a comment

Repurposing of Existing Drugs to Prevent Dementia? (BBC News / Science Advances /Alzheimer’s Research UK)

Summary A number of drugs, already approved as safe for the treatment of other conditions, and which could help protect against Alzheimer’s Disease, are said to have been detected and short-listed for further investigation. Full Text Link Reference Alzheimer’s preventative … Continue reading

Posted in Alzheimer's Society, Alzheimer’s Research UK, Animal Studies, BBC News, Charitable Bodies, For Doctors (mostly), For Nurses and Therapists (mostly), For Researchers (mostly), In the News, International, NHS Digital (Previously NHS Choices), Pharmacological Treatments, Quick Insights, UK, Universal Interest | Tagged , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , | Leave a comment

Brief Introduction to the DIAN-TU Study (BBC News)

Summary The Dominantly Inherited Alzheimer Network Trials Unit (DIAN-TU) is based at University College Hospital in London, and has the aim of finding ways to prevent the development of Alzheimer’s Disease in people at high risk, before physical / clinical … Continue reading

Posted in Alzheimer’s Research UK, BBC News, Diagnosis, For Doctors (mostly), For Nurses and Therapists (mostly), For Researchers (mostly), In the News, Pharmacological Treatments, Quick Insights, UK, Universal Interest | Tagged , , , , , , , , , , , , , , , , , , , , , , , , , , , | Leave a comment

Cancer Drugs to Assist Nerve Regeneration? (BBC News / Brain)

Summary Researchers at Imperial College London have suggested that cancer drugs called nutlins may influence mechanisms with the potential for enabling certain aspects of CNS nerve regeneration (at least in animal studies involving severed spinal cords): Full Text Link Reference … Continue reading

Posted in Animal Studies, BBC News, For Doctors (mostly), For Nurses and Therapists (mostly), For Researchers (mostly), In the News, International, Quick Insights, UK | Tagged , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , | Leave a comment

Innovation Via Untested Medicines / Repurposing of Approved Drugs? (BBC News / BMJ)

Summary The law may soon be changed in England and Wales to allow untested medicines to be used under certain conditions. People dying from cancer might one day be allowed to be treated voluntarily with unlicensed drugs, under the Medical … Continue reading

Posted in BBC News, For Doctors (mostly), For Researchers (mostly), In the News, National, Pharmacological Treatments, Quick Insights, Standards, UK, Universal Interest | Tagged , , , , , , , , , , , , , , , , , | Leave a comment

Use of Anti-Depressants to Slow Alzheimer’s Disease Onset? (BBC News / Science Translational Medicine / PNAS)

Summary Recent research into transgenic mice (and early, small-scale investigations with people) suggests that the anti-depressant citalopram could be used to slow the onset of Alzheimer’s Disease. This work in the United States appears to show that citalopram may counteract … Continue reading

Posted in Animal Studies, BBC News, For Researchers (mostly), In the News, International, Quick Insights, Universal Interest | Tagged , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , | Leave a comment