Tag Archives: Perelman School of Medicine: University of Pennsylvania

Holistic Consideration of Apathy in Dementia (Journal of the American Geriatrics Society)

Summary A recent review of apathy proposes an integrative (holistic) model for understanding the condition, in common with other forms of BPSD. “As with other BPSD, …neural mechanisms alone do not completely account for the syndrome – individual, caregiver and … Continue reading

Posted in Depression, For Carers (mostly), For Doctors (mostly), For Nurses and Therapists (mostly), For Researchers (mostly), Integrated Care, International, Mental Health, Models of Dementia Care, Non-Pharmacological Treatments, Person-Centred Care, Pharmacological Treatments, Quick Insights, Systematic Reviews, Universal Interest | Tagged , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , | Leave a comment

Dementia with Lewy Bodies: Updated DLB Consortium Diagnosis and Management Consensus Report (Neurology)

Summary The Dementia with Lewy Bodies (DLB) Consortium has published an updated set of recommendations on diagnosis and management of DLB. Clinical features and diagnostic biomarkers are covered, with guidance on their interpretation. Previously omitted aspects of Lewy-related pathology are … Continue reading

Posted in Antipsychotics, Diagnosis, For Doctors (mostly), For Nurses and Therapists (mostly), For Researchers (mostly), International, Management of Condition, Mental Health, Models of Dementia Care, Non-Pharmacological Treatments, Person-Centred Care, Quick Insights, UK | Tagged , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , | Leave a comment

Cognitive Reserve: the Benefits of Mentally Challenging Occupations and Bilingualism (Daily Mail / Neurology / CMAJ / Neuropsychology)

Summary Research published in the Neurology journal suggests that having a challenging occupation can potentially halve the rate of decline in memory and thinking capacity in later life, compared to pursuing mentally undemanding work. Workers performing complex jobs (such as … Continue reading

Posted in For Doctors (mostly), For Nurses and Therapists (mostly), For Researchers (mostly), In the News, International, Quick Insights, Statistics, UK, Universal Interest | Tagged , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , | Leave a comment

Common Medicines Associated With Dementia Risk (BBC News / JAMA Internal Medicine)

Summary A US study, published in JAMA Internal Medicine, concerning long-term use of anticholinergic-type drugs (those which block the neurotransmitter acetylcholine), in older people, has discovered an association with the risk of developing dementia. Higher doses and prolonged use of … Continue reading

Posted in BBC News, For Carers (mostly), For Doctors (mostly), For Nurses and Therapists (mostly), For Researchers (mostly), In the News, International, NHS Digital (Previously NHS Choices), Pharmacological Treatments, Practical Advice, Quick Insights, Statistics, Universal Interest | Tagged , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , | Leave a comment

Reducing Antipsychotic Prescribing for BPSD (BMJ / JAMA / JAMA Psychiatry / BJCP)

Summary This BMJ “Change page” article discusses the potential harms associated with use of antipsychotics in people with dementia, and covers guidelines recommending restrictions in their use. Risperidone is the antipsychotic recommended for use in the treatment of aggression associated … Continue reading

Posted in Acute Hospitals, Antipsychotics, Community Care, For Doctors (mostly), For Nurses and Therapists (mostly), For Researchers (mostly), International, Management of Condition, Mental Health, Models of Dementia Care, Non-Pharmacological Treatments, Person-Centred Care, Pharmacological Treatments, Practical Advice, Quick Insights, Standards, Statistics, UK | Tagged , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , | Leave a comment

Stroke Mortality and Weekend Working (BBC News / PLoS Medicine)

Summary A recent study indicates that stroke survival is associated with the number of nurses available at weekends, but not the frequency of doctors’ ward rounds. The importance of the so-called “weekend effect” is widely recognised across many areas of … Continue reading

Posted in Acute Hospitals, BBC News, For Doctors (mostly), For Nurses and Therapists (mostly), For Researchers (mostly), In the News, Quick Insights, Standards, Stroke, UK, Universal Interest | Tagged , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , | Leave a comment

Neuropsychiatric Symptoms and Cognition in Patients with a Recent Diagnosis of Parkinson Disease (BBC News / Neurology)

Summary People with newly diagnosed Parkinson’s Disease appear to be twice as likely to suffer from depression and anxiety than the general population. Depression in Parkinson’s patients appears to remain under-recognised and often untreated. Full Text Link Reference Depression ‘more … Continue reading

Posted in BBC News, Depression, For Carers (mostly), For Doctors (mostly), For Nurses and Therapists (mostly), For Researchers (mostly), In the News, International, Mental Health, Parkinson's Disease, Quick Insights, Statistics, Universal Interest | Tagged , , , , , , , , , , , , , , , , , , , , , , , , , | Leave a comment

BBC’s Day of the Body Clock (BBC News / PNAS / Science / NHS Choices / Lancet / Heart)

Summary Cancer, heart disease, type-2 diabetes, infections and obesity have been linked to insufficient and / or disrupted sleep. Full Text Link Reference Gallagher, J. (2014). ‘Arrogance’ of ignoring need for sleep. London: BBC Health News, May 12th 2014. Irregular … Continue reading

Posted in Animal Studies, BBC News, For Doctors (mostly), For Nurses and Therapists (mostly), For Researchers (mostly), In the News, International, NHS Digital (Previously NHS Choices), Quick Insights, UK, Universal Interest | Tagged , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , | Leave a comment

Brain Cell Death Resulting From Sleep Deprivation? (BBC News / Journal of Neuroscience)

Summary There is some evidence to indicate that prolonged lack of sleep in mice may result in 25% permanent loss of certain brain cells. Full Text Link Reference Briggs, H. (2014). Lost sleep leads to loss of brain cells, study … Continue reading

Posted in Animal Studies, BBC News, For Researchers (mostly), In the News, International, Mental Health, Quick Insights, Universal Interest | Tagged , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , | Leave a comment

Alzheimer’s Disease: Genetics Research Breakthrough (BBC News / NHS Choices / Nature Genetics)

Summary An international collaboration of geneticists from 145 academic institutions investigating Alzheimer’s Disease have performed a meta-analysis of data about the DNA of 17,000 patients and 37,000 healthy people. Their analysis of genome-wide association studies (GWAS) has identified 21 genetic … Continue reading

Posted in BBC News, For Doctors (mostly), For Nurses and Therapists (mostly), For Researchers (mostly), In the News, International, NHS Digital (Previously NHS Choices), Quick Insights, Universal Interest | Tagged , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , | Leave a comment