Tag Archives: Pre-Dementia (MCI)

Cognitive Impairment in Parkinson’s Disease: the State of Current Understanding (NPJ Parkinson’s Disease)

Posted on July 9, 2018 by Dementia and Elderly Care News

Summary The following review summarises a recent conference on the topic of cognitive impairment encountered in Parkinson’s Disease. Full Text Link Reference Goldman, JG. Vernaleo, BA. [and] Camicioli, R. [et al] (2018). Cognitive impairment in Parkinson’s disease: a report from … Continue reading →

Posted in Acute Hospitals, Charitable Bodies, Community Care, Diagnosis, For Carers (mostly), For Doctors (mostly), For Nurses and Therapists (mostly), For Researchers (mostly), For Social Workers (mostly), Integrated Care, International, Management of Condition, Mental Health, Models of Dementia Care, Non-Pharmacological Treatments, Parkinson's Disease, Person-Centred Care, Quick Insights, Statistics, Universal Interest | Tagged Barrow Neurological Institute (Phoenix), Boston University, Boston University Medical Campus, Canada, Center for Neuromodulation: Barrow Neurological Institute, Center for Neurorehabilitation: Boston University, Charles E. Schmidt College of Medicine: Florida Atlantic University, Cognitive Decline, Cognitive Impairment, Cognitive Impairment in Parkinson's Disease, College of Health Sciences: Rush University Medical Center, Department of Clinical and Health Psychology: University of Florida, Department of Clinical Neuropsychology: Barrow Neurological Institute, Department of Clinical Nutrition: Rush University Medical Center, Department of Health and Aging: Rush University Medical Center, Department of Medicine: University of Alberta, Department of Medicine: University of Pennsylvania, Department of Neurological Sciences: Rush University Medical Center, Department of Neurology: Boston University Medical Campus, Department of Neurology: University of Iowa, Department of Neurology: University of Maryland School of Medicine, Department of Neurology: University of Miami, Department of Neurology: University of Pennsylvania, Department of Physical Therapy and Athletic Training: Boston University, Department of Psychiatry and Psychology: Mayo Clinic (Rochester), Department of Psychiatry: Rutgers The State University of New Jersey, Division of Neuropsychology: University of Miami, Edmond J Safra Program in Parkinson’s Disease: Toronto Western Hospital, Florida Atlantic University, Lewy Body Parkinson Disease, MCI: Mild Cognitive Impairment, Mediterranean-DASH Intervention for Neurodegenerative Delay: MIND, Memory Controllability Inventory (MCI), Mild Cognitive Impairment in Parkinson's Disease (MCI-PD), Morton and Gloria Shulman Movement Disorders Centre: Toronto Western Hospital, Movement Disorder Society (MDS) Task Forces for PDD and PD-MCI Diagnostic Criteria, Neurology Service: Iowa City, NPJ Parkinson’s Disease, Parkinson's Disease Foundation Community Choice Research Award Program, Parkinson's Foundation, Parkinson’s Dementia, Parkinson’s Disease Dementia, PD Cognitive Impairment, Pre-Dementia (MCI), Risk of Cognitive Impairment and Dementia, Rush University Medical Center, Rutgers The State University of New Jersey, Section of Parkinson Disease and Movement Disorders: Rush University Medical Center, Toronto Western Hospital, United States, University Health Network: University of Toronto, University of Alberta, University of Florida, University of Iowa, University of Maryland School of Medicine, University of Miami, University of Pennsylvania, University of South Florida, University of Toronto, Unmet Needs, USA, Veterans Affairs Health Care System (Iowa City) | Leave a comment

Spatial Navigation Tests For Disorientation May Identify Preclinical Alzheimer’s Disease? (BBC News / Science / JGCR / Brain)

Posted on October 26, 2015 by Dementia and Elderly Care News

Summary A German study indicates that persons with a high genetic risk of developing Alzheimer’s Disease might be identified early by monitoring their performance in tests involving navigation through a virtual maze. Full Text Link Reference Virtual reality maze ‘predicts … Continue reading →

Posted in BBC News, Diagnosis, For Doctors (mostly), For Researchers (mostly), In the News, International, Quick Insights, Universal Interest | Tagged APOE e4 Carriers, APOE-4 Allele, Apoe-ε4 Allele, APOE-ε4 Carriers, Apolipoprotein E (APOE) e4 Allele, Apolipoprotein E (Apoe)-ε4 Genotype, At-Genetic-Risk Alzheimer's Disease, BBC Health News, Behavioural Biomarkers, Big Data, Bonn, Brain (Journal), Center for Economics and Neuroscience: University of Bonn, Computer Games, Conversion to Dementia From Prodromal Disease, Dementia, Dementia Research, Department of Clinical Educational and Health Psychology: University College London, Department of Clinical Neurosciences: University of Cambridge, Department of Electrical Engineering: University College London, Department of Epileptology: University of Bonn, Department of Neuropsychology: Ruhr-University Bochum, Department of Psychiatry: University of Cambridge, Department of Psychology: Ulm University, Department of Psychology: University of Bonn, Diagnosis, Differential Diagnosis, Digital Diagnostic Tools, Disorientation, Donders Institute for Brain Cognition and Behaviour: Radboud University, Early Detection of Preclinical Disease, Early-Onset Alzheimer's Gene, Early-Onset Dementia, Entorhinal Cortex, Entorhinal Dysfunction in Adults at Genetic Risk for Alzheimer’s Disease, Gamification, German Center for Neurodegenerative Diseases (DZNE), German Centre for Neurodegenerative Diseases (Bonn), Germany, Germany. Department of Epileptology: University of Bonn, Grid-Cell-Like Representations, Grid-Cell-Like Representations in Adults at Genetic Risk for Alzheimer’s Disease, HTC Vive iVR Equipment, Information Technology, Institute of Cognitive Neuroscience: Ruhr-University Bochum, Institute of Cognitive Neuroscience: University College London, Journal of Geriatric Care and Research (JGCR), MRC Cognition and Brain Sciences Unit: University of Cambridge, Netherlands, Neurodegenerative Disease, Non-Invasive Biomarkers, Pre-Dementia (MCI), Preclinical Alzheimer's Disease, Preclinical Indicators and Dementia, Preclinical Indicators in Alzheimer's Disease, Prodromal Alzheimer's Disease, Radboud University, Risk Factors, Ruhr-University Bochum, Science (American Association for the Advancement of Science), Science Journal, Sea Hero Quest (SHQ) Game, Spatial Disorientation, Spatial Navigation Benchmarks, Spatial Navigation Tests of Disorientation, Ulm University, University College London, University of Bonn, University of Cambridge, Virtual Mazes | Leave a comment

Brief Introduction to the DIAN-TU Study (BBC News)

Posted on October 23, 2015 by Dementia and Elderly Care News

Summary The Dominantly Inherited Alzheimer Network Trials Unit (DIAN-TU) is based at University College Hospital in London, and has the aim of finding ways to prevent the development of Alzheimer’s Disease in people at high risk, before physical / clinical … Continue reading →

Posted in Alzheimer’s Research UK, BBC News, Diagnosis, For Doctors (mostly), For Nurses and Therapists (mostly), For Researchers (mostly), In the News, Pharmacological Treatments, Quick Insights, UK, Universal Interest | Tagged Alzheimer’s Disease Biomarkers, BBC Health News, Biomarkers, Conversion Rates, Conversion to Dementia, Conversion to Dementia From Prodromal Disease, Dementia Research, DIAN-TU Study, DIAN-TU Trial, Disease-Modifying Therapies, Disease-Modifying Therapies for Dementia, Dominantly Inherited Alzheimer Network Trials Unit (DIAN-TU), Early-Onset Alzheimer's Gene, Early-Onset Dementia, Immunotherapy Drugs, MCI: Mild Cognitive Impairment, Mild Cognitive Impairment (MCI), Neurological Research, Off-Label Drug Repurposing Trials, Potential Repurposing of Drugs to Slow Progression of Alzheimer’s Disease, Pre-Dementia (MCI), Preclinical Biomarkers and Dementia, Preclinical Biomarkers in Alzheimer's Disease, Prodromal Alzheimer's Disease, Rates of Conversion From Mild Cognitive Impairment to Dementia, Repurposing of Drugs, University College Hospital, University College Hospitals NHS Foundation Trust | Leave a comment

Increasing Number of Volunteers for Dementia Research (BBC News / NIHR)

Posted on August 14, 2015 by Dementia and Elderly Care News

Summary The National Institute for Health Research has reported a significant increase in the number of people volunteering to participate in medical research into dementia. Roughly 22,000 people are taking part in 100 different studies into the degenerative brain diseases; … Continue reading →

Posted in Acute Hospitals, Alzheimer's Society, BBC News, Community Care, Diagnosis, For Carers (mostly), For Doctors (mostly), For Nurses and Therapists (mostly), For Researchers (mostly), In the News, Local Interest, Management of Condition, Mental Health, Models of Dementia Care, National, NIHR, Non-Pharmacological Treatments, Patient Care Pathway, Pharmacological Treatments, Quick Insights, Statistics, UK, Universal Interest | Tagged Ageing, Ageing and Dementia, BBC Health News, Dementia Challenge, Dementia Research, Join Dementia Research, Join Dementia Research National Service, Join Dementia Research: Clinical Trials Matchmaker Service, National Institute for Health Research (NIHR), Neurodegenerative Disease Research, Neurodegenerative Diseases, Neurodegenerative Disorders, Neurodegenerative Research, NIHR Dementia and Neurodegenerative Diseases Research Network (DeNDRoN), NIHR: National Institute for Health Research, Non-Invasive Biomarkers, Participation in Research, Participation in Research Studies, Patient Involvement in Research, Patient Participation Groups, Patient Participation Groups (PPGs), Practice Participation Groups, Pre-Dementia (MCI), Prime Minister's Challenge on Dementia, Public Involvement in Research, Public Participation in Research, Research Engagement and Involvement Activities, Science of Ageing | Leave a comment

Join Dementia Research: Clinical Trials Matchmaker Service (Department of Health / Dementia Challenge / BBC News / NIHR)

Posted on February 25, 2015 by Dementia and Elderly Care News

Summary The “Join Dementia Research” website assists people with dementia to learn about, and become involved in, dementia research. A new enhancement to this service allows people with dementia (or their families / carers for example, acting on their behalf) … Continue reading →

Posted in Acute Hospitals, Alzheimer's Society, Alzheimer’s Research UK, BBC News, Charitable Bodies, Community Care, Department of Health, Diagnosis, For Carers (mostly), For Doctors (mostly), For Nurses and Therapists (mostly), For Researchers (mostly), For Social Workers (mostly), In the News, Local Interest, Management of Condition, Mental Health, Models of Dementia Care, National, NHS, NHS England, NIHR, Non-Pharmacological Treatments, Patient Care Pathway, Patient Information, Personalisation, Pharmacological Treatments, Practical Advice, Quick Insights, UK, Universal Interest | Tagged Ageing, Ageing and Dementia, Alzheimer Scotland, Alzheimer's Research UK, Alzheimer's Society, BBC Health News, Clinical Research Network (NIHR' CRN), Clinical Research Network (NIHR), Dementia Challenge, Dementia Research, Dementia Research Centre (DRC) at University College London, Dementia Research Centre: University College London, Dementias and Neurodegenerative Diseases Research Network (DeNDRoN), Department of Public Health and Policy: University of Liverpool, Hilary Evans: Charity Director of Alzheimer’s Research UK, Join Dementia Research, Join Dementia Research National Service, Join Dementia Research: Clinical Trials Matchmaker Service, Join Dementia Research: Recruitment Onto Dementia Studies, MCI: Mild Cognitive Impairment, Mild Cognitive Impairment (MCI), National Institute for Health Research (NIHR), National Institute for Health Research (NIHR): History, National Institute for Health Research (NIHR): Origins, NIHR Clinical Research Network (CRN), NIHR Research Activity League Table, NIHR: National Institute for Health Research, NIHR’s Clinical Research Networks, Non-Invasive Biomarkers, Participation in Research, Participation in Research Studies, Patient Involvement in Research, Patient Participation Groups, Patient Participation Groups (PPGs), Practice Participation Groups, Pre-Dementia (MCI), Prime Minister's Challenge on Dementia, Professor Martin Rossor: Former Director of the NIHR Dementia and Neurodegenerative Disease Research Network (DeNDRoN), Professor Martin Rossor: NIHR National Director for Dementia Research, Professor Martin Rossor: UCL Institute of Neurology, Public Involvement in Research, Public Participation in Research, Research Activity League Table (NIHR CRN), Research Engagement and Involvement Activities, Science of Ageing, Small Business Research Initiative for Healthcare (SBRI) Healthcare Programme, UCL Partners, University College London, University College London (UCL), University of Liverpool | Leave a comment

National Screening for Dementia Not Recommended (UK NSC / AHRQ / Annals of Internal Medicine / Epidemiology / International Journal of Epidemiology)

Posted on January 19, 2015 by Dementia and Elderly Care News

Summary The UK National Screening Committee (UK NSC) has upheld previous recommendations against screening people aged 65 and over for dementia. This decision follows an extensive review of the evidence. The UK NSC has concluded that tests for dementia, which … Continue reading →

Promoting Awareness of Current Trials and Encouraging Public Engagement in Dementia Research (NIHR / Join Dementia Research)

Posted on December 30, 2014 by Dementia and Elderly Care News

Summary The “Join Dementia Research” website has been designed to assist people to learn more about dementia research which is ongoing, whether in their local areas or across the UK. This service offers the public opportunities to get involved in … Continue reading →

Posted in Alzheimer's Society, Alzheimer’s Research UK, Charitable Bodies, Diagnosis, For Carers (mostly), For Doctors (mostly), For Nurses and Therapists (mostly), For Social Workers (mostly), Local Interest, Management of Condition, Models of Dementia Care, National, NIHR, Non-Pharmacological Treatments, Northern Ireland, Parkinson's Disease, Patient Care Pathway, Patient Information, Pharmacological Treatments, Practical Advice, Quick Insights, UK, Universal Interest, Wales | Tagged 24 Days of Dementia Research: Advent Calendar 2014, Advent Calendar: 24 Days of Dementia Research (2014), AFFECT Study, Ageing, Ageing and Dementia, Amlodipine, Amyloid and Tau Imaging, Amyloid Beta, Amyloid Imaging, Amyloid Proteins, Amyloid-β (Aβ), “GE180” Study, Bangor University, Behavioural Frontotemporal Dementia (bvFTD), Behavioural Variant Frontotemporal Dementia (bvFTD), Beta-Amyloid, Beta-Amyloid Plaques, Biomarkers, Brain Beta Amyloid Load, Cognitive Rehabilitation, Cognitive Rehabilitation Therapies (CRTs), Cognitive Rehabilitation Therapy, DAPA - Dementia and Physical Activity Trial, DAPA Study, Dementia Research, Dementia Research Centre (DRC) at University College London, Dementia Research Centre: University College London, Dementia Risk Prevention, Dementias and neurodegeneration (DeNDRoN) Specialty, Dementias and Neurodegenerative Diseases Research Network (DeNDRoN), DeNDRoN: Dementias and Neurodegenerative Diseases Research Network, Diagnostic Testing, Down Syndrome, Dr Tamara Al-Janabi: University College London, Early-Onset Dementia, Environmental and Lifestyle Factors, Environmental Hazards, Environmental Issues, Epidemiology, Exercise, Exercise And Lifestyle For Older People, Exercise for Dementia, Exercise Medicine, Exercise Therapy, GE180, GE180 Tracer / Marker, Genetic Triggers, Genetics, Goal-Oriented Cognitive Rehabilitation in Early-Stage Alzheimer's Disease Trial (GREAT), GREAT Study: Goal-Oriented Cognitive Rehabilitation in EArly sTage Dementia, GREAT: Goal-Oriented Cognitive Rehabilitation in Early-Stage Alzheimer's Disease Trial, IDEAL Project, IDEAL Project: Research in Ageing and Cognitive Health at Bangor University, IDEAL Study, Imperial College London, Improving the Experience of Dementia and Enhancing Active Life (IDEAL), Inflammation, Institute of Psychiatry at King’s College London, Institute of Psychiatry: King's College London, Join Dementia Research, Join Dementia Research National Service, Join Dementia Research: Recruitment Onto Dementia Studies, Kings College London, Leuco-Methylthioninium (LMTM), Living Well with Dementia, Living Well With Memory Difficulties’ (GREAT Study), London Down Syndrome Consortium (LonDownS), MCI: Mild Cognitive Impairment, Mild Cognitive Impairment (MCI), National Institute for Health Research (NIHR), Neuroinflammation, Neuroinflammation and Amyloid Study, NIHR: National Institute for Health Research, Non-Invasive Biomarkers, Participation in Research, Participation in Research Studies, Patient Involvement in Research, Patient Participation Groups, Patient Participation Groups (PPGs), Physical Activity, Physical Activity Programmes, Physical Exercise, Practice Participation Groups, Pre-Dementia (MCI), PREVENT Study, Prevention, Prevention of Vascular Dementia, Professor Simon Lovestone: King’s College London’s Department of Old Age Psychiatry, Prophylaxis, PROTECT Study, Public Health, Public Involvement in Research, Public Participation in Research, Regular Exercise, Research Engagement and Involvement Activities, Science of Ageing, Subcortical Ischemic Vascular Dementia (SIVD), Subcortical Vascular Dementia, Talking Therapies, University College London, University College London (UCL), University of Warwick, University of Warwick Medical School, Vascular Dementia: Prevention, Warwick Medical School: University of Warwick, Young Onset Alzheimer’s Disease (YOAD) Study, Young Onset Dementia (YOD), Young-Onset Dementia | Leave a comment

Phase III Gantenerumab Trial for Prodromal Alzheimer’s Disease Discontinued (Biospace Inc)

Posted on December 23, 2014 by Dementia and Elderly Care News

Summary The Scarlet RoAD study (a Phase III trial), researching the anti-amyloid drug Gantenerumab for the possible treatment of prodromal (pre-dementia) Alzheimer’s Disease, has been abandoned following disappointing results. Gantenerumab-related research (in a different Phase III investigation) is still underway … Continue reading →

Posted in For Doctors (mostly), For Researchers (mostly), In the News, International, Pharmacological Treatments, Quick Insights | Tagged Amyloid, Amyloid Beta Protein, Amyloid Proteins, Amyloid-β (Aβ), Anti-Amyloid Therapies, Antidementia Drugs, Big Pharma, Biospace, Clinical Trials (Phase I Through Phase III), Crenezumab, Drug Trials, Drug Trials Failure Rate, Drug-Development Pipeline, Gantenerumab, MorphoSys, Pharmaceutical Industry, Pharmaceuticals, Phase III MARIANNE Study (Breast Cancer), Pre-Dementia (MCI), Prodromal Alzheimer's Disease, RG1577, Roche, Scarlet RoAD Study | Leave a comment

Mild Cognitive Impairment: Diagnosis and Management (JAMA)

Posted on December 18, 2014 by Dementia and Elderly Care News

Summary Mild cognitive impairment (MCI), defined as the “pre-dementia stage on the continuum of cognitive decline, characterized by objective impairment in cognition that is not severe enough to require help with usual activities of daily living”, tends to occur in … Continue reading →

Posted in Community Care, For Nurses and Therapists (mostly), For Researchers (mostly), International, Non-Pharmacological Treatments, Pharmacological Treatments, Quick Insights, Systematic Reviews, Universal Interest | Tagged Aerobic Exercise, Cognitive Activity, Cognitive Decline, Department of Internal Medicine, Department of Neurology and Stroke Program: University of Michigan, Institute for Healthcare Policy and Innovation: University of Michigan, Institute for Social Research: University of Michigan, Institute of Gerontology: University of Michigan, JAMA, Late-Life Cognitive Decline, MCI, MCI: Mild Cognitive Impairment, Mental Wellbeing, Mild Cognitive Impairment, Mild Cognitive Impairment (MCI), Mild Cognitive Impairment More Prevalent in Men, National Institute on Aging (NIA), Physical Activity, Physical Activity as a Protective Factor for Cognitive Decline and Dementia, Pre-Dementia (MCI), Primary Care, Progression of Mild Cognitive Impairment to Dementia, Rates of Conversion From Mild Cognitive Impairment to Dementia, Risk and Protective Factors for Cognitive Decline and Dementia, Social Engagement, Social Inclusion, United States, University of Michigan, USA, Veterans Affairs Center for Clinical Management Research: Michigan | Leave a comment

Screening to Identify People at Risk of Dementia (JRCPE)

Posted on April 11, 2014 by Dementia and Elderly Care News

Summary This article in the Journal of the Royal College of Physicians of Edinburgh presents a balanced account of both sides of the argument with regards to whether screening for dementia might be beneficial, and concerning the recent controversy on … Continue reading →

Posted in Acute Hospitals, Alzheimer's Society, Community Care, Diagnosis, For Carers (mostly), For Doctors (mostly), For Nurses and Therapists (mostly), For Researchers (mostly), National, Patient Care Pathway, Quick Insights, Scotland, UK, Universal Interest | Tagged Best Interest Decisions, Best Interests, Best Interests of Patients, Blood Pressure, Cardiovascular Risk, Cardiovascular Risk Factors and Cognitive Decline, Case Finding for Patients with Dementia, Cochrane-Registered Prevention Reviews, Complex Best Interests Decision Making, Conflicts of Interests, Continuum of Cognitive Impairment, Dementia Case Finding, Dementia Case Finding Scheme, Dementia Challenge, Dementia Diagnosis, Dementia Screening Debate, Diagnosis and Referral, Diagnosis and Support, Diagnosis of Dementia, Diagnosis Rates, Diagnosis Rates (Regional UK), Diet, Difficult Conversations, Doctor-Patient Relationships, Early Diagnosis, Early Diagnosis of Alzheimer's Disease, Early Screening, Ethical Considerations, Ethical Dilemmas, Ethical Issues of Dementia Care, Ethics and Decision-Making, Exercise, General Practice, GPs, Improving Diagnosis, Incentive Payments, Incentives, Journal of the Royal College of Physicians of Edinburgh, JRCPE: Journal of the Royal College of Physicians of Edinburgh, MCI: Mild Cognitive Impairment, Medical Ethics, Mild Cognitive Impairment (MCI), Misdiagnosis, Modifiable Risk Factors, Montreal Cognitive Assessment (MoCA), NAPC, National Association of Primary Care, National Association of Primary Care (NAPC), NHS Health Check, NHS Health Checks Programme, Norwich Medical School, Obesity, Over-Diagnosis, Perverse Incentives, Physical Activity, Physical Exercise, Post-Diagnosis Support, Post-Diagnostic Dementia Support, Post-Diagnostic Support, Potential Harms of Diagnosis, Pre-Dementia (MCI), Preventable Dementia (Public Health England), Preventative Care, Prevention, Preventive Care, Prime Minister's Challenge on Dementia, Prime Minister’s Dementia Challenge, Regular Exercise, Risk Factors, Screening, Screening for Dementia, Smoking, Target-Driven Priorities, Timely Diagnosis, University of East Anglia, Vascular Risk Factors, Vested Interests, Watling Medical Centre (UK), Western University: London Health Sciences Centre | Leave a comment

Tag Archives: Pre-Dementia (MCI)

Spatial Navigation Tests For Disorientation May Identify Preclinical Alzheimer’s Disease? (BBC News / Science / JGCR / Brain)

Brief Introduction to the DIAN-TU Study (BBC News)

Increasing Number of Volunteers for Dementia Research (BBC News / NIHR)

National Screening for Dementia Not Recommended (UK NSC / AHRQ / Annals of Internal Medicine / Epidemiology / International Journal of Epidemiology)

Phase III Gantenerumab Trial for Prodromal Alzheimer’s Disease Discontinued (Biospace Inc)

Screening to Identify People at Risk of Dementia (JRCPE)

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