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Tag Archives: Pre-Dementia (MCI)
Increasing Number of Volunteers for Dementia Research (BBC News / NIHR)
Summary The National Institute for Health Research has reported a significant increase in the number of people volunteering to participate in medical research into dementia. Roughly 22,000 people are taking part in 100 different studies into the degenerative brain diseases; … Continue reading
Posted in Acute Hospitals, Alzheimer's Society, BBC News, Community Care, Diagnosis, For Carers (mostly), For Doctors (mostly), For Nurses and Therapists (mostly), For Researchers (mostly), In the News, Local Interest, Management of Condition, Mental Health, Models of Dementia Care, National, NIHR, Non-Pharmacological Treatments, Patient Care Pathway, Pharmacological Treatments, Quick Insights, Statistics, UK, Universal Interest
Tagged Ageing, Ageing and Dementia, BBC Health News, Dementia Challenge, Dementia Research, Join Dementia Research, Join Dementia Research National Service, Join Dementia Research: Clinical Trials Matchmaker Service, National Institute for Health Research (NIHR), Neurodegenerative Disease Research, Neurodegenerative Diseases, Neurodegenerative Disorders, Neurodegenerative Research, NIHR Dementia and Neurodegenerative Diseases Research Network (DeNDRoN), NIHR: National Institute for Health Research, Non-Invasive Biomarkers, Participation in Research, Participation in Research Studies, Patient Involvement in Research, Patient Participation Groups, Patient Participation Groups (PPGs), Practice Participation Groups, Pre-Dementia (MCI), Prime Minister's Challenge on Dementia, Public Involvement in Research, Public Participation in Research, Research Engagement and Involvement Activities, Science of Ageing
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Join Dementia Research: Clinical Trials Matchmaker Service (Department of Health / Dementia Challenge / BBC News / NIHR)
Summary The “Join Dementia Research” website assists people with dementia to learn about, and become involved in, dementia research. A new enhancement to this service allows people with dementia (or their families / carers for example, acting on their behalf) … Continue reading
Posted in Acute Hospitals, Alzheimer's Society, Alzheimer’s Research UK, BBC News, Charitable Bodies, Community Care, Department of Health, Diagnosis, For Carers (mostly), For Doctors (mostly), For Nurses and Therapists (mostly), For Researchers (mostly), For Social Workers (mostly), In the News, Local Interest, Management of Condition, Mental Health, Models of Dementia Care, National, NHS, NHS England, NIHR, Non-Pharmacological Treatments, Patient Care Pathway, Patient Information, Personalisation, Pharmacological Treatments, Practical Advice, Quick Insights, UK, Universal Interest
Tagged Ageing, Ageing and Dementia, Alzheimer Scotland, Alzheimer's Research UK, Alzheimer's Society, BBC Health News, Clinical Research Network (NIHR' CRN), Clinical Research Network (NIHR), Dementia Challenge, Dementia Research, Dementia Research Centre (DRC) at University College London, Dementia Research Centre: University College London, Dementias and Neurodegenerative Diseases Research Network (DeNDRoN), Department of Public Health and Policy: University of Liverpool, Hilary Evans: Charity Director of Alzheimer’s Research UK, Join Dementia Research, Join Dementia Research National Service, Join Dementia Research: Clinical Trials Matchmaker Service, Join Dementia Research: Recruitment Onto Dementia Studies, MCI: Mild Cognitive Impairment, Mild Cognitive Impairment (MCI), National Institute for Health Research (NIHR), National Institute for Health Research (NIHR): History, National Institute for Health Research (NIHR): Origins, NIHR Clinical Research Network (CRN), NIHR Research Activity League Table, NIHR: National Institute for Health Research, NIHR’s Clinical Research Networks, Non-Invasive Biomarkers, Participation in Research, Participation in Research Studies, Patient Involvement in Research, Patient Participation Groups, Patient Participation Groups (PPGs), Practice Participation Groups, Pre-Dementia (MCI), Prime Minister's Challenge on Dementia, Professor Martin Rossor: Former Director of the NIHR Dementia and Neurodegenerative Disease Research Network (DeNDRoN), Professor Martin Rossor: NIHR National Director for Dementia Research, Professor Martin Rossor: UCL Institute of Neurology, Public Involvement in Research, Public Participation in Research, Research Activity League Table (NIHR CRN), Research Engagement and Involvement Activities, Science of Ageing, Small Business Research Initiative for Healthcare (SBRI) Healthcare Programme, UCL Partners, University College London, University College London (UCL), University of Liverpool
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National Screening for Dementia Not Recommended (UK NSC / AHRQ / Annals of Internal Medicine / Epidemiology / International Journal of Epidemiology)
Summary The UK National Screening Committee (UK NSC) has upheld previous recommendations against screening people aged 65 and over for dementia. This decision follows an extensive review of the evidence. The UK NSC has concluded that tests for dementia, which … Continue reading
Posted in Acute Hospitals, Community Care, Department of Health, Diagnosis, For Doctors (mostly), For Nurses and Therapists (mostly), For Researchers (mostly), Guidelines, Models of Dementia Care, National, NHS, Patient Care Pathway, Person-Centred Care, Practical Advice, Public Health England, Quick Insights, Standards, UK, Universal Interest
Tagged (Hepatocellular Carcinoma: Alphafetoprotein), Activities of Daily Living (ADL), Activities of Daily Living Scale, ADAS-Cog, ADAS-Cog: Alzheimer’s Disease Assessment Scale - Cognitive Subscale, Addenbrooke's Cognitive Examination (ACE), Addenbrooke's Cognitive Examination-Revised (ACE-R), Alzheimer's Disease Assessment Scale (ADAS-Cog11), Alzheimer’s Early Screening, Annals of Internal Medicine, Australia, Benefits of Detection and Early Intervention, Best Interest Decisions, Best Interests, Best Interests of Patients, Blackfriars Consensus Statement, Bond University, Brief Assessments, Cambridge Cognitive Examination (CAMCOG), CAMCOG-R: Cambridge Cognitive Examination-Revised, Case Finding, Case Finding for Patients with Dementia, Centre for Research in Evidence-Based Practice: Bond University, CERAD-NP, Clock Drawing Test, Clock Drawing Test (CDT), Cognition Disorders, Cognitive Assessment Tools, Cognitive Impairment, Complex Best Interests Decision Making, Consortium to Establish a Registry for Alzheimer’s Disease – NP (CERAD-NP), Counter-Intuitive Screening Evidence, Counterintuitive Screening Evidence, Dementia Case Finding, Dementia Case Finding Scheme, Dementia Challenge, Dementia Diagnosis, Dementia Screening, Dementia Screening Debate, DemTect, Department of Medicine: Stanford University School of Medicine, Department of Statistics: Stanford University School of Humanities and Sciences, Diagnosis and Referral, Diagnosis and Support, Diagnosis Gap, Diagnosis of Dementia, Diagnosis Rates, Difficult Conversations, Doctor-Patient Relationships, Dr Anne Mackie: Director of Programmes (UK NSC), Dr Charles Alessi: Dementia Lead for PHE, Early Diagnosis, Early Diagnosis of Alzheimer's Disease, Early Screening, Effectiveness of Early Detection and Treatment, Ethical Considerations, Ethical Dilemmas, Ethical Issues of Dementia Care, Ethics and Decision-Making, General Practice, GPs, Harms of Detection and Early Intervention or Treatment, Improving Diagnosis, Incentive Payments, International Journal of Epidemiology, International Journal of Geriatric Psychiatry, Mass Screening, MCI: Mild Cognitive Impairment, Memory Assessments, Mild Cognitive Impairment, Mild Cognitive Impairment (MCI), Montreal Cognitive Assessment (MoCA), Neuropsychological Tests, olutions for Public Health (SPH), Opinions About Meaning of Overdiagnosis: National Community Survey of Australians, PHE: Public Health England, Picture Based Assessments, Population Screening for Dementia Deyond Passive Case-Finding, Post-Diagnosis Support, Pre-Dementia (MCI), Prevalence of Cognitive Impairment, Primary Prevention Interventions, Prime Minister's Challenge on Dementia, Prime Minister’s Dementia Challenge, Progression of Mild Cognitive Impairment to Dementia, Quality Premium Payments, Recommendation against national dementia screening. London: Public Health England (PHE), Risk Assessment, Risk of Overdiagnosis Associated With Screening, Rowland Universal Dementia Assessment Scale (RUDAS), School of Public Health: University of Sydney, Screening, Screening for Cognitive Impairment, Screening for Cognitive Impairment in Older Adults, Screening for Dementia, Screening Programmes, Screening Tests, Screening: Counter-Intuitive Evidence, Screening: Counter-Intuitive Evidence (Abdominal Aortic Aneurysm), Screening: Counter-Intuitive Evidence (Abdominal Aortic Aneurysm: Ultrasound), Screening: Counter-Intuitive Evidence (Breast Cancer), Screening: Counter-Intuitive Evidence (Breast Cancer: Breast Self-Exam), Screening: Counter-Intuitive Evidence (Breast Cancer: Clinical Breast Exam), Screening: Counter-Intuitive Evidence (Breast Cancer: Mammography), Screening: Counter-Intuitive Evidence (Cardiovascular Disease), Screening: Counter-Intuitive Evidence (Cardiovascular Disease: Echocardiography), Screening: Counter-Intuitive Evidence (Cervical Cancer), Screening: Counter-Intuitive Evidence (Cervical Cancer: Cytology), Screening: Counter-Intuitive Evidence (Cervical Cancer: Human Papilloma Virus), Screening: Counter-Intuitive Evidence (Cervical Cancer: Visual Inspection), Screening: Counter-Intuitive Evidence (Colorectal Cancer), Screening: Counter-Intuitive Evidence (Colorectal Cancer: Faecal Occult Blood Test [FOBT]), Screening: Counter-Intuitive Evidence (Colorectal Cancer: Fecal Occult Blood Test [FOBT]), Screening: Counter-Intuitive Evidence (Colorectal Cancer: Flexible Sigmoidoscopy With or Without FOBT), Screening: Counter-Intuitive Evidence (Colorectal Cancer: Flexible Sigmoidoscopy), Screening: Counter-Intuitive Evidence (Colorectal Cancer: Single Flexible Sigmoidoscopy), Screening: Counter-Intuitive Evidence (Hepatocellular Carcinoma), Screening: Counter-Intuitive Evidence (Hepatocellular Carcinoma: Alphafetoprotein and Ultrasound), Screening: Counter-Intuitive Evidence (Lung Cancer), Screening: Counter-Intuitive Evidence (Lung Cancer: CA-125), Screening: Counter-Intuitive Evidence (Lung Cancer: Chest X-Ray), Screening: Counter-Intuitive Evidence (Lung Cancer: Chest X-Ray and Cytology), Screening: Counter-Intuitive Evidence (Lung Cancer: CT Scan), Screening: Counter-Intuitive Evidence (Multiple Flexible Sigmoidoscopy), Screening: Counter-Intuitive Evidence (Oral Cancer), Screening: Counter-Intuitive Evidence (Oral Cancer: Visual Exam), Screening: Counter-Intuitive Evidence (Ovarian Cancer), Screening: Counter-Intuitive Evidence (Ovarian Cancer: CA–125), Screening: Counter-Intuitive Evidence (Prostate Cancer), Screening: Counter-Intuitive Evidence (Prostate Cancer: Prostate-Specific-Antigen), Screening: Counter-Intuitive Evidence (Type 2 Diabetes), Screening: Counter-Intuitive Evidence (Type 2 Diabetes: Fasting Blood Glucose and HbA1c), Solutions for Public Health (SPH) Review, Stanford Prevention Research Center: Stanford University School of Medicine, Stanford University School of Medicine, Systematic Population Dementia Screening Programme: Not Recommended (UK NSC), Target Culture, Target-Driven Behaviour, Target-Driven Priorities, Targeted Screening, Timely Diagnosis, Trail Making Assessments, Trail Making Test, Trail Making Tests, Transition from Cognitive Impairment to Dementia, U.S. Preventive Services Task Force (USPSTF), UK National Screening Committee, UK National Screening Committee (UK NSC), United States Preventive Services Task Force, United States Preventive Services Task Force (USPSTF), University of Sydney, USA Department of Health Research and Policy, USA Department of Health Research and Policy: Stanford University School of Medicine, Verbal Fluency, Verbal Fluency Assessments
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Promoting Awareness of Current Trials and Encouraging Public Engagement in Dementia Research (NIHR / Join Dementia Research)
Summary The “Join Dementia Research” website has been designed to assist people to learn more about dementia research which is ongoing, whether in their local areas or across the UK. This service offers the public opportunities to get involved in … Continue reading
Posted in Alzheimer's Society, Alzheimer’s Research UK, Charitable Bodies, Diagnosis, For Carers (mostly), For Doctors (mostly), For Nurses and Therapists (mostly), For Social Workers (mostly), Local Interest, Management of Condition, Models of Dementia Care, National, NIHR, Non-Pharmacological Treatments, Northern Ireland, Parkinson's Disease, Patient Care Pathway, Patient Information, Pharmacological Treatments, Practical Advice, Quick Insights, UK, Universal Interest, Wales
Tagged 24 Days of Dementia Research: Advent Calendar 2014, Advent Calendar: 24 Days of Dementia Research (2014), AFFECT Study, Ageing, Ageing and Dementia, Amlodipine, Amyloid and Tau Imaging, Amyloid Beta, Amyloid Imaging, Amyloid Proteins, Amyloid-β (Aβ), “GE180” Study, Bangor University, Behavioural Frontotemporal Dementia (bvFTD), Behavioural Variant Frontotemporal Dementia (bvFTD), Beta-Amyloid, Beta-Amyloid Plaques, Biomarkers, Brain Beta Amyloid Load, Cognitive Rehabilitation, Cognitive Rehabilitation Therapies (CRTs), Cognitive Rehabilitation Therapy, DAPA - Dementia and Physical Activity Trial, DAPA Study, Dementia Research, Dementia Research Centre (DRC) at University College London, Dementia Research Centre: University College London, Dementia Risk Prevention, Dementias and neurodegeneration (DeNDRoN) Specialty, Dementias and Neurodegenerative Diseases Research Network (DeNDRoN), DeNDRoN: Dementias and Neurodegenerative Diseases Research Network, Diagnostic Testing, Down Syndrome, Dr Tamara Al-Janabi: University College London, Early-Onset Dementia, Environmental and Lifestyle Factors, Environmental Hazards, Environmental Issues, Epidemiology, Exercise, Exercise And Lifestyle For Older People, Exercise for Dementia, Exercise Medicine, Exercise Therapy, GE180, GE180 Tracer / Marker, Genetic Triggers, Genetics, Goal-Oriented Cognitive Rehabilitation in Early-Stage Alzheimer's Disease Trial (GREAT), GREAT Study: Goal-Oriented Cognitive Rehabilitation in EArly sTage Dementia, GREAT: Goal-Oriented Cognitive Rehabilitation in Early-Stage Alzheimer's Disease Trial, IDEAL Project, IDEAL Project: Research in Ageing and Cognitive Health at Bangor University, IDEAL Study, Imperial College London, Improving the Experience of Dementia and Enhancing Active Life (IDEAL), Inflammation, Institute of Psychiatry at King’s College London, Institute of Psychiatry: King's College London, Join Dementia Research, Join Dementia Research National Service, Join Dementia Research: Recruitment Onto Dementia Studies, Kings College London, Leuco-Methylthioninium (LMTM), Living Well with Dementia, Living Well With Memory Difficulties’ (GREAT Study), London Down Syndrome Consortium (LonDownS), MCI: Mild Cognitive Impairment, Mild Cognitive Impairment (MCI), National Institute for Health Research (NIHR), Neuroinflammation, Neuroinflammation and Amyloid Study, NIHR: National Institute for Health Research, Non-Invasive Biomarkers, Participation in Research, Participation in Research Studies, Patient Involvement in Research, Patient Participation Groups, Patient Participation Groups (PPGs), Physical Activity, Physical Activity Programmes, Physical Exercise, Practice Participation Groups, Pre-Dementia (MCI), PREVENT Study, Prevention, Prevention of Vascular Dementia, Professor Simon Lovestone: King’s College London’s Department of Old Age Psychiatry, Prophylaxis, PROTECT Study, Public Health, Public Involvement in Research, Public Participation in Research, Regular Exercise, Research Engagement and Involvement Activities, Science of Ageing, Subcortical Ischemic Vascular Dementia (SIVD), Subcortical Vascular Dementia, Talking Therapies, University College London, University College London (UCL), University of Warwick, University of Warwick Medical School, Vascular Dementia: Prevention, Warwick Medical School: University of Warwick, Young Onset Alzheimer’s Disease (YOAD) Study, Young Onset Dementia (YOD), Young-Onset Dementia
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Phase III Gantenerumab Trial for Prodromal Alzheimer’s Disease Discontinued (Biospace Inc)
Summary The Scarlet RoAD study (a Phase III trial), researching the anti-amyloid drug Gantenerumab for the possible treatment of prodromal (pre-dementia) Alzheimer’s Disease, has been abandoned following disappointing results. Gantenerumab-related research (in a different Phase III investigation) is still underway … Continue reading
Posted in For Doctors (mostly), For Researchers (mostly), In the News, International, Pharmacological Treatments, Quick Insights
Tagged Amyloid, Amyloid Beta Protein, Amyloid Proteins, Amyloid-β (Aβ), Anti-Amyloid Therapies, Antidementia Drugs, Big Pharma, Biospace, Clinical Trials (Phase I Through Phase III), Crenezumab, Drug Trials, Drug Trials Failure Rate, Drug-Development Pipeline, Gantenerumab, MorphoSys, Pharmaceutical Industry, Pharmaceuticals, Phase III MARIANNE Study (Breast Cancer), Pre-Dementia (MCI), Prodromal Alzheimer's Disease, RG1577, Roche, Scarlet RoAD Study
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Mild Cognitive Impairment: Diagnosis and Management (JAMA)
Summary Mild cognitive impairment (MCI), defined as the “pre-dementia stage on the continuum of cognitive decline, characterized by objective impairment in cognition that is not severe enough to require help with usual activities of daily living”, tends to occur in … Continue reading
Posted in Community Care, For Nurses and Therapists (mostly), For Researchers (mostly), International, Non-Pharmacological Treatments, Pharmacological Treatments, Quick Insights, Systematic Reviews, Universal Interest
Tagged Aerobic Exercise, Cognitive Activity, Cognitive Decline, Department of Internal Medicine, Department of Neurology and Stroke Program: University of Michigan, Institute for Healthcare Policy and Innovation: University of Michigan, Institute for Social Research: University of Michigan, Institute of Gerontology: University of Michigan, JAMA, Late-Life Cognitive Decline, MCI, MCI: Mild Cognitive Impairment, Mental Wellbeing, Mild Cognitive Impairment, Mild Cognitive Impairment (MCI), Mild Cognitive Impairment More Prevalent in Men, National Institute on Aging (NIA), Physical Activity, Physical Activity as a Protective Factor for Cognitive Decline and Dementia, Pre-Dementia (MCI), Primary Care, Progression of Mild Cognitive Impairment to Dementia, Rates of Conversion From Mild Cognitive Impairment to Dementia, Risk and Protective Factors for Cognitive Decline and Dementia, Social Engagement, Social Inclusion, United States, University of Michigan, USA, Veterans Affairs Center for Clinical Management Research: Michigan
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Screening to Identify People at Risk of Dementia (JRCPE)
Summary This article in the Journal of the Royal College of Physicians of Edinburgh presents a balanced account of both sides of the argument with regards to whether screening for dementia might be beneficial, and concerning the recent controversy on … Continue reading
Posted in Acute Hospitals, Alzheimer's Society, Community Care, Diagnosis, For Carers (mostly), For Doctors (mostly), For Nurses and Therapists (mostly), For Researchers (mostly), National, Patient Care Pathway, Quick Insights, Scotland, UK, Universal Interest
Tagged Best Interest Decisions, Best Interests, Best Interests of Patients, Blood Pressure, Cardiovascular Risk, Cardiovascular Risk Factors and Cognitive Decline, Case Finding for Patients with Dementia, Cochrane-Registered Prevention Reviews, Complex Best Interests Decision Making, Conflicts of Interests, Continuum of Cognitive Impairment, Dementia Case Finding, Dementia Case Finding Scheme, Dementia Challenge, Dementia Diagnosis, Dementia Screening Debate, Diagnosis and Referral, Diagnosis and Support, Diagnosis of Dementia, Diagnosis Rates, Diagnosis Rates (Regional UK), Diet, Difficult Conversations, Doctor-Patient Relationships, Early Diagnosis, Early Diagnosis of Alzheimer's Disease, Early Screening, Ethical Considerations, Ethical Dilemmas, Ethical Issues of Dementia Care, Ethics and Decision-Making, Exercise, General Practice, GPs, Improving Diagnosis, Incentive Payments, Incentives, Journal of the Royal College of Physicians of Edinburgh, JRCPE: Journal of the Royal College of Physicians of Edinburgh, MCI: Mild Cognitive Impairment, Medical Ethics, Mild Cognitive Impairment (MCI), Misdiagnosis, Modifiable Risk Factors, Montreal Cognitive Assessment (MoCA), NAPC, National Association of Primary Care, National Association of Primary Care (NAPC), NHS Health Check, NHS Health Checks Programme, Norwich Medical School, Obesity, Over-Diagnosis, Perverse Incentives, Physical Activity, Physical Exercise, Post-Diagnosis Support, Post-Diagnostic Dementia Support, Post-Diagnostic Support, Potential Harms of Diagnosis, Pre-Dementia (MCI), Preventable Dementia (Public Health England), Preventative Care, Prevention, Preventive Care, Prime Minister's Challenge on Dementia, Prime Minister’s Dementia Challenge, Regular Exercise, Risk Factors, Screening, Screening for Dementia, Smoking, Target-Driven Priorities, Timely Diagnosis, University of East Anglia, Vascular Risk Factors, Vested Interests, Watling Medical Centre (UK), Western University: London Health Sciences Centre
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