Tag Archives: Prion Diseases

Possible Future Treatment of CJD? (BBC News)

Posted on October 10, 2018 by Dementia and Elderly Care News

Summary University College London Hospitals NHS Foundation Trust (UCLH)’s National Prion Clinic has been granted the go-ahead to test the use of a man-made antibody treatment (PRN100), with a view to halting or slowing the progression of sporadic CJD. “We … Continue reading →

Pollution of All Types: A Broad Review of the Health Implications (Department of Health / BBC News)

Posted on March 6, 2018 by Dementia and Elderly Care News

Summary The Chief Medical Officer’s latest annual report summarises the latest emerging evidence about all types of pollution. The press release talks of four main topics: Pollution arising from healthcare. Pollution and health inequalities. Emerging pollution-related issues. Pollution measurement and … Continue reading →

Posted in Acute Hospitals, BBC News, Community Care, Department of Health, Department of Health and Social Care (DHSC), For Doctors (mostly), For Nurses and Therapists (mostly), For Researchers (mostly), In the News, Integrated Care, National, NHS, Quick Insights, Standards, Statistics, Systematic Reviews, UK, Universal Interest | Tagged Air Pollution, Air Pollution and Public Health, Air Pollution and Risk of Dementia, Air Pollution Cost for Health, Air Pollution Costs, Air Pollution Economic Cost on Public Health, Air Pollution in the UK, Air Quality, Air Quality Abatement, Airborne Particulate Matter, Annual Report of the Chief Medical Officer 2017: Health Impacts of All Pollution, BBC Health News, BBC Science and Environment News, Behaviour Change Theory, Big Data on Environmental Pollution, Bioaerosols, Biocides, Biological Changes and Apical Outcomes, Biological Pollutants, Biomarkers, Bisphenols and Phthalates, Blue Light, Burden of Disease From Pollutants, Carbon Nanotubes (CNTs), Chemical Substances of Unknown or Variable Composition (UVCBs), Chief Medical Officer: Professor Dame Sally Davies, City of York Council, CleanSpace Monitoring, CleanSpace Tags, Committee on the Medical Effects of Air Pollutants (COMEAP), Communicating Complexity, Communication About Mortality Effects, Contaminated Land, Cost and Benefits of Air Quality, Department of Epidemiology and Biostatistics: Imperial College London, Department of Geology and Environmental Sciences: State University of New York in Fredonia, Department of Health Datasets, Dioxins and Polychlorinated Biphenyls (PCBs), Economic Consequences of Air Pollution, Economic Cost of Air Pollution on Health, Economic Cost of Pollution Impact on Health, Economic Valuation of Air Pollution, Endocrine-Disrupting Chemicals (EDCs), Environment Agency, Environmental and Health Service Pollution, Environmental Hazards and Emergencies Department: Public Health England, Environmental Health Professionals (EHPs), Environmental Justice, Environmental Public Health Tracking (EPHT), Environmental Risk Factors, Environmental Surveillance, Epidemiology, Epidemiology and Statistics, European Human Biomonitoring Initiative (HBM4EU), Exeter Medical School, Exeter Medical School: University of Exeter, Exposure to Fine Particulate Matter, Faculty of Health and Medicine: University of Lancaster, Flame Retardants (FR), Greenhouse Gases (GHG) in Healthcare, Health and Occupation Research (THOR) Surveillance Network, Health Based Economic Assessment of Air Pollution, Health Cost of Pollution, Health Data Research UK (HDR UK), Health Datasets, Health Economic Cost of Pollution, Health Impact of Pollution, Health Impacts of Air Pollution, Health Impacts of All Pollution, Health Inequalities, Health Pollution Cost, Imperial College Business School, Imperial College London, Indoor Air Pollution, Infection Control of CJD vCJD and Other Human Prion Diseases in Healthcare and Community Settings, International Agency for Research on Cancer (IARC), Intrinsically Photosensitive Retinal Ganglion Cells (iPRGCs), King’s College London, Lancaster Environment Centre: University of Lancaster, Lead Pollution, Light Pollution, Liveable Cities Perspective From London and Birmingham Dwellers, London Air Quality Network (LAQN), Long-Term Exposure to Ambient Air Pollution, Low Emission Strategy (LES), Magnetite (Iron Oxide Particles), Magnetite From Air Pollution, Magnetite Pollution Nanoparticles, Magnetite Pollution Particles, Microplastics, Microplastics in Bottled Water, Modifiable Risk Factors, MRC-PHE Centre for Environment and Health: Imperial College London, Nanomaterials (NMs), Nanoscale Magnetite, National Health and Nutrition Examination Survey (NHANES), Noise Pollution, Nottinghamshire Healthcare NHS Foundation Trust, Occupational Exposures, One Planet York Initiative, Open University, Orb Media, Outdoor Air Quality and Health, Overlapping Risk Factors, Particulate Matter, Perfluorinated Chemicals (PFCs), Pesticides, Pharmaceutical Pollution in England, Pharmaceutical Supply Chain Initiative (PSCI), Plastic Particles (Microplastics), Plastic Pollution, Pollution and Inequality, Pollution and Public Health, Pollution Assessment, Pollution in Health and Care, Pollution Inequalities, Pollution Interventions, Pollution Linked to One Sixth of Deaths, Pollution Measurement, Pollution of All Types, Pollution Surveillance, Polycyclicaromatic Hydrocarbons (PAHs), Potentially Modifiable Socio-Environmental Risk Factors, Potentially Modifiable Socio-Environmental Risk Factors for Dementia, Precautionary Principle, Prion Diseases, Professor Dame Sally Davies, Professor Dame Sally Davies: the Chief Medical Officer (CMO) for England, Public Health, Public Health and Health Improvement, Public Health England, Public Understanding of Risk: University of Cambridge, Radioactive Particles, Rapid Inquiry Facility (RIF), RecoMed: Helping Hospitals to Recycle PVC and Save Costs, Reducing 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International Agency for Research on Cancer (IARC), Yancheng Science Park: Jiangsu Province | Leave a comment

No Room For Complacency Regarding Population Subclinical vCJD? (PLoS Pathogens)

Posted on January 22, 2018 by Dementia and Elderly Care News

Summary After a near-miss mini-epidemic of Variant Creutzfeldt-Jakob Disease (vCJD) in the 1990s, experts caution that: “It is essential that we do not become complacent and continue both surveillance and risk management strategies in both human and animal prion diseases”. … Continue reading →

Posted in Universal Interest | Tagged Biomarkers, Biotechnology and Biological Sciences Research Council (BBSRC), Blood Organ and Tissue Donation, Blood Transfusions, Blood-Based Biomarkers, Bovine Spongiform Encephalopathy (BSE), BSE Exposure, Centre for Dementia Prevention: University of Edinburgh, CJD, CJD Risk Management, CJD Surveillance, Creutzfeldt-Jakob Disease (CJD), Creuzfeldt Jacob Disease (CJD), Decontamination of Surgical Instruments, Dementia Prevention, Diack and Manson Laboratories, Donor Blood, Edinburgh Neuroscience, Edinburgh Neuroscience: University of Edinburgh, Epidemiology, Epidemiology and Statistics, Hypothetical Prodromes of Dementia, Infectivity of vCJD Infection, Mad Cow Disease, Medical Instruments, Medical Procedures, Misfolded Prion Protein (PrP), National CJD Research and Surveillance Unit (NCJDRSU), National CJD Research and Surveillance Unit: University of Edinburgh, National Institute for Health Research (NIHR) Policy Research Programme, NCJDRSU: National CJD Research and Surveillance Unit, Neurodegeneration, Neurodegenerative Disease Research, Neurodegenerative Diseases, PLoS Pathogens, Prevalence of CJD, Prion Diseases, Prionics Blood Test, Public Health, Public Health Risk, Public Health Surveillance, Roslin Institute (Edinburgh), Roslin Institute [and] R(D)SVS: University of Edinburgh, Subclinical vCJD, UK Blood Supply, University of Edinburgh, Variant CJD and Blood, Variant Creutzfeldt-Jakob Disease, vCJD Blood Testing, vCJD Carriers in UK, vCJD Infection | Leave a comment

Grounds for Cautious Optimism Regarding Two Drugs Re-Purposed for Neurodegenerative Diseases? (BBC News / MRC / NHS Choices / Brain)

Posted on April 20, 2017 by Dementia and Elderly Care News

Summary Animal research, involving mice, has indicated promising results for the potential of two re-purposed drugs in helping to slow or halt the progression of a number of neurodegenerative brain diseases, including dementia. “The best known drug of the pair … Continue reading →

Posted in Animal Studies, BBC News, For Researchers (mostly), In the News, National, NHS Digital (Previously NHS Choices), Parkinson's Disease, Pharmacological Treatments, Quick Insights, UK, Universal Interest | Tagged Abnormal Prion Protein, Alzheimer's Disease, Alzheimer's Research UK, Alzheimer’s Drug Discovery Foundation, Alzheimer’s Research UK (ARUK), Alzheimer’s Research UK Drug Discovery Institute, Amyloid Beta, Amyloid Beta Protein, Amyloid Proteins, Amyloid-β (Aβ), Amyloid-β (Aβ) Accumulation, Autoimmune Attacks, Autoimmune Cell Defences, BBC Health News, Behind the Headlines, Brain (Journal), Centre for Analytical Bioscience: University of Nottingham, CJD, Creutzfeldt-Jakob Disease, Creuzfeldt Jacob Disease (CJD), Department of Clinical Neurosciences: University of Cambridge, Dibenzoylmethane, Dibenzoylmethane (DBM): Potential Anti-Cancer Drug, Disease-Modifying Therapies, Disease-Modifying Therapies for Dementia, Dr David Dexter: Parkinson's UK, Dr Doug Brown: Director of Research and Development at Alzheimer's Society, Drug Discovery Programmes, eIF2a-P-Mediated Translational Repression (Pathway of Neurodegeneration), Frontotemporal Dementia (FTD), Huntingtin Protein, Huntington’s Disease, α-Synuclein, α-Synuclein Aggregation, Lentivirally Mediated RNA Interference (RNAi), Medical Research Council (MRC), Medical Research Council (UK), Medical Research Council Toxicology Unit: University of Leicester, Medical Research Council’s (MRC) Toxicology Unit, Microscopic Worms, Misfolded Prion Protein (PrP), Misfolded Proteins, Motor Neurone Disease (MND), MRC Toxicology Unit: University of Leicester, MRC: Medical Research Council, Multiple Sclerosis, National Institute for Neurological Disorders and Stroke, Neurodegeneration, Neurodegenerative Disease Research, Neurodegenerative Diseases, Neuronal Loss, Neuroprotection, Parkinson's, Potential Repurposing of Drugs to Slow Progression of Alzheimer’s Disease, Prion Diseases, Prion Protein (PrP(C)), Prion-Infected Mice, Prof. Giovanna Mallucci, Professor Giovanna Mallucci: Associate Drector of UK Dementia Research Institute, Protein Misfolding, Rare Prion Diseases, Repurposing of Drugs, Synucleinopathy, Tau, Tau Protein, Tauopathy, Translational Research, Transmissible Spongiform Encephalopathies, Trazodone, Trazodone Hydrochloride (Antidepressant), UK Dementia Research Institute, UK Dementia Research Institute (UK DRI), Unfolded Protein Response (UPR), University of Cambridge, University of Leicester, University of Nottingham, Worms: C. elegans | Leave a comment

Urine Test for Creutzfeldt-Jakob Disease (CJD)? (BBC News / MRC / JAMA Neurology / NEJM)

Posted on October 4, 2016 by Dementia and Elderly Care News

Summary It may one day be possible to use a non-invasive diagnostic urine test to discover whether or not patients have sporadic Creutzfeldt-Jakob Disease (sCJD). Full Text Link Reference A urine test for Creutzfeldt-Jakob Disease may be possible. London: Medical … Continue reading →

Alzheimer’s Disease Contractable Via Brain Surgery? (NHS Choices / Swiss Medical Weekly)

Posted on February 22, 2016 by Dementia and Elderly Care News

Summary Further evidence points to a theoretical risk of Alzheimer’s Disease being potentially transmissible during surgical procedures, in the manner of Creutzfeldt-Jakob disease (CJD). Full Text Link Reference New clues that Alzheimer’s may have been spread during surgery. London: NHS … Continue reading →

Posted in Acute Hospitals, For Doctors (mostly), For Nurses and Therapists (mostly), For Researchers (mostly), In the News, International, NHS Digital (Previously NHS Choices), Quick Insights, Universal Interest | Tagged Abnormal Prion Protein, Aβ Deposition in Grey Matter, Aβ in Blood Vessel Walls, Aβ Seeds, Aβ Seeds: Transmitted Iatrogenically with iCJD, Aβ-Containing Inoculates Induce Cerebral β-Amyloidosis, Alzheimer-Type Neuropathology in Iatrogenic Creutzfeldt-Jakob Disease After Dural Grafting, Alzheimer’s Disease Contracted Via Brain Surgery, Alzheimer’s Disease Transmission (Hypothesis), Amyloid, Amyloid Beta Protein, Amyloid Proteins, Amyloid-β (Aβ), Amyloid-β Protein, Austria, Behind the Headlines, Brain Parenchymal Aβ Plaques, Cleaning and Decontamination, Congophilic Amyloid Angiopathy, Contaminated Surgical Instruments, Decontamination of Surgical Instruments, Dural Grafting, Human Transmission of Aβ, Human Transmission of Amyloid-β Pathology, Human-Derived Growth Hormones, Iatrogenic CJD, Iatrogenic Creutzfeldt-Jakob Disease, Iatrogenic Creutzfeldt-Jakob Disease After Dural Grafting, Iatrogenic Routes of Prion Transmission Generalisable to Aβ (Hypothesis), Iatrogenic Routes of Prion Transmission Generalisable to Proteopathic Seeds of Neurodegenerative Disease (Hypothesis), Induction of Cerebral β-Amyloidosis: Intracerebral Versus Systemic Aβ Inoculation, Institute of Neurology: Medical University Vienna, Institute of Neuropathology: University Hospital Zurich, Medical University Vienna, Neurodegenerative Disease Research, Neurodegenerative Diseases, Neurodegenerative Disorders, Neuroepidemiology, Prion Diseases, Protein Seeds (Amyloid), Protein Seeds of Alzheimer’s Disease (Hypothesis), Proteopathic Seeds of Neurodegenerative Disease, Risk Factors and Preventive Interventions for Alzheimer Disease, Risk of Prion-Like Disease Transmission by Alzheimer- or Parkinson-Associated Protein Particles, Surgical Transmission of Prions, Swiss Medical Weekly, Switzerland, Transmissible Alzheimer's Disease (Theoretical Risk), Transmissible Spongiform Encephalopathy Agents: General Principles of Decontamination and Waste Disposal, University Hospital Zurich | Leave a comment

Potential Risk of Alzheimer’s Disease Transmission (BBC News / NHS Choices / Nature / MRC)

Posted on September 10, 2015 by Dementia and Elderly Care News

Summary There may be a theoretical risk of Alzheimer’s Disease being transmissible during surgical procedures, in the manner of Creutzfeldt-Jakob disease (CJD). This hypothesis has arisen as a result of the examination of the brains of eight patients who had … Continue reading →

Posted in BBC News, For Doctors (mostly), For Nurses and Therapists (mostly), For Researchers (mostly), In the News, NHS Digital (Previously NHS Choices), Quick Insights, UK, Universal Interest | Tagged Abnormal Prion Protein, Aβ Deposition in Grey Matter, Aβ in Blood Vessel Walls, Aβ Seeds, Aβ Seeds: Transmitted Iatrogenically with iCJD, Aβ-Containing Inoculates Induce Cerebral β-Amyloidosis, Alzheimer-Type Neuropathology in Iatrogenic Creutzfeldt-Jakob Disease After Dural Grafting, Alzheimer’s Disease and Blood Transfusion, Alzheimer’s Disease Transmission (Hypothesis), Amyloid, Amyloid Beta Protein, Amyloid Proteins, Amyloid-Beta Deposition in APP Transgenic Mice, Amyloid-β (Aβ), Amyloid-β Protein, BBC Health News, Behind the Headlines, Brain Deposition of Amyloid, Brain-Derived Human Growth Hormone (HGH), Cadaver-Derived Growth Hormone, Cerebral Amyloid Angiopathy, Coexistence of Alzheimer-Type Neuropathology in Creutzfeldt-Jakob Disease, Consortium to Establish a Registry for Alzheimer’s Disease (CERAD), Contaminated Surgical Instruments, Contamination of Injections, Creutzfeldt Jacob Disease (CJD), Creutzfeldt-Jakob Disease (CJD), Creutzfeldt-Jakob Disease in United Kingdom Patients Treated With Human Pituitary Growth Hormone, Decontamination of Surgical Instruments, Department of Neurodegenerative Disease: UCL Institute of Neurology, Exogenous Induction of Cerebral β-Amyloidogenesis, Grey Matter and Vascular Amyloid-β (Aβ) Pathology, Human Pituitary-Derived Growth Hormone, Human Transmission of Amyloid-β Pathology, Human-Derived Growth Hormones, Iatrogenic CJD, Iatrogenic Creutzfeldt-Jakob Disease, Iatrogenic Routes of Prion Transmission Generalisable to Aβ (Hypothesis), Iatrogenic Routes of Prion Transmission Generalisable to Proteopathic Seeds of Neurodegenerative Disease (Hypothesis), Induction of Cerebral β-Amyloidosis: Intracerebral Versus Systemic Aβ Inoculation, Induction of Tau Pathology by Intracerebral Infusion of Amyloid-β-Containing Brain Extract, Medical Research Council, Medical Research Council (MRC), Medical Research Council Prion Unit, Misfolded Proteins, MRC Clinical Trials Unit at University College London, National Institute of Health Research (NIHR), National Prion Clinic: National Hospital for Neurology and Neurosurgery, National Prion Monitoring Cohort Study, Nature, Neurodegenerative Disease Research, Neurodegenerative Diseases, Neurodegenerative Disorders, Neuroepidemiology, Neuropathologic Assessment of Alzheimer’s Disease, NHS National Prion Clinic (NPC) in London, Peripheral Administration of Tau Aggregates Triggers Intracerebral Tauopathy in Transgenic Mice, Potential Infectivity of Alzheimer and Parkinson Disease Proteins in Recipients of Cadaver-Derived Human Growth Hormone, Prion Diseases, Protein Seeds (Amyloid), Protein Seeds of Alzheimer’s Disease (Hypothesis), Proteopathic Seeds of Neurodegenerative Disease, Risk Factors and Preventive Interventions for Alzheimer Disease, Risk of Prion-Like Disease Transmission by Alzheimer- or Parkinson-Associated Protein Particles, Seeded β-Amyloid in APP Transgenic Mice, Surgical Transmission of Prions, Transmissible Alzheimer's Disease (Theoretical Risk), Transmissible and Non-Transmissible Amyloidoses, UCLH / UCL Biomedical Research Centre, UCLH / UCL Dementia Biomedical Research Unit, University College London (UCL) | Leave a comment

Tag Archives: Prion Diseases

Possible Future Treatment of CJD? (BBC News)

No Room For Complacency Regarding Population Subclinical vCJD? (PLoS Pathogens)

Grounds for Cautious Optimism Regarding Two Drugs Re-Purposed for Neurodegenerative Diseases? (BBC News / MRC / NHS Choices / Brain)

Alzheimer’s Disease Contractable Via Brain Surgery? (NHS Choices / Swiss Medical Weekly)

Potential Risk of Alzheimer’s Disease Transmission (BBC News / NHS Choices / Nature / MRC)

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