Tag Archives: Prion Protein

Possible Future Treatment of CJD? (BBC News)

Summary University College London Hospitals NHS Foundation Trust (UCLH)’s National Prion Clinic has been granted the go-ahead to test the use of a man-made antibody treatment (PRN100), with a view to halting or slowing the progression of sporadic CJD. “We … Continue reading

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Urine Test for Creutzfeldt-Jakob Disease (CJD)? (BBC News / MRC / JAMA Neurology / NEJM)

Summary It may one day be possible to use a non-invasive diagnostic urine test to discover whether or not patients have sporadic Creutzfeldt-Jakob Disease (sCJD). Full Text Link Reference A urine test for Creutzfeldt-Jakob Disease may be possible. London: Medical … Continue reading

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Evolutionary Mutation of Human Prion Protein May Prevent Prion Diseases? (NHS Choices / BBC News / Nature)

Summary A natural human mutation (called V127) in the gene encoding prion protein may offer resistance to CJD. A study using mice with this genetic mutation appears to confirm resistance to prion diseases. This finding may in future help in … Continue reading

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Lancet Seminar on Parkinson’s Disease (Lancet / Advances in Integrative Medicine / Translational Proteomics / Parkinson’s UK / BBC News)

Summary Coinciding with Parkinson’s Awareness Week 2015 (April 20th – 26th 2015), the following Lancet review / seminar covers the clinical features, risk factors, pathology, genetics, pathogenesis, diagnosis and treatment of Parkinson’s Disease. Full Text Link (Note: This article requires … Continue reading

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The Epidemiology, Diagnosis and Management of CJD in the UK (Public Health England / NCJDRSU)

Summary “Creutzfeldt-Jakob disease (CJD) is a rare and ultimately fatal degenerative brain disease. It is one of a group of diseases called Transmissible Spongiform Encephalopathies (TSEs)”. Health Protection Agency (HPA): Part of Public Health England (Since April 2013) Information sources concerning … Continue reading

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Binding of CJD Prions and Alzheimer’s Disease Protein Blocked (NHS Choices)

[A version of this item appears in: Dementia: the Latest Evidence Newsletter (RWHT), Volume 1 Issue 12, July 2011]. Summary An unexpected discovery has allowed scientists to block Alzheimer’s disease, according to The Independent. Researchers developing drugs to treat Creutzfeldt-Jakob … Continue reading

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