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Tag Archives: Progression of Mild Cognitive Impairment to Dementia
Brain Training Game May Improve Symptoms of Amnestic Mild Cognitive Impairment? (NHS Choices / International Journal of Neuropsychopharmacology)
Summary A small research study, involving older persons with mild cognitive impairment (MCI), indicates that cognitive training delivered in the form of a brain training game (the app called “Game Show”) may help improve memory and might potentially reduce / … Continue reading
Posted in For Researchers (mostly), In the News, International, Management of Condition, NHS Digital (Previously NHS Choices), Non-Pharmacological Treatments, Person-Centred Care, Quick Insights, UK, Universal Interest
Tagged Active Engagement, Amnestic Mild Cognitive Impairment (a-MCI), Amnestic Mild Cognitive Impairment (aMCI), Apathy Evaluation Scale (AES), Behind the Headlines, Brain Training, Brain Training Games, Brief Visuospatial Memory Test-Revised (BVMT-R), Cambridge and Peterborough NHS Foundation Trust, Cambridge Neuropsychological Test Automated Battery Paired Associates Learning (PAL), Cambridge University Hospitals NHS Foundation Trust, CANTAB Choice Reaction Time (CRT), CANTAB Paired Associates Learning, Cognitive Training, Cognitive Training Exercises, Computer Games, Computerised Touch Screen Games, Critical Appraisals, Dementias and Neurodegeneration NIHR Clinical Research Network (Eastern DeNDRon), Department of Clinical Neurosciences and MRC Cognition and Brain Sciences Unit: University of Cambridge, Department of Psychiatry: University of Cambridge, Department of Psychological Sciences: University of East Anglia, Effects of Cognitive Training on General Cognition and Neuropsychiatric Symptoms, Enjoyment and General Engagement, Episodic Memory, Eton College, Game Show app, Game Show Cognitive Training app, Gamification, Gamification (Improved Engagement and Motivation), Gamified Cognitive Training, Geriatric Depression Scale (GDS Short Form), Hospital Anxiety and Depression Scale (HADS), Information Technology, International Journal of Neuropsychopharmacology, Intrinsic Motivation, Involvement and Participation, Ipad Technology, Janssen Pharmaceutical, Johnson and Johnson, Mild Cognitive Impairment, Mild Cognitive Impairment (MCI), Mini Mental State Examination (MMSE), Motivational Enhancement, MRC / Wellcome Trust Behavioural and Clinical Neuroscience Institute, Neuropsychological Assessment, New Technology, Norfolk and Suffolk NHS Foundation Trust, Paired Associates Learning, Positive Engagement, Progression of Mild Cognitive Impairment to Dementia, Rates of Conversion From Mild Cognitive Impairment to Dementia, University of Cambridge, University of East Anglia, Wallitt Foundation, Wellcome Trust, Wellcome Trust Behavioural and Clinical Neuroscience Institute: University of Cambridge
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Alzheimer’s Disease: Solanezumab Drug Trial Flops (BBC News / Alzheimer’s and Dementia)
Summary The phase 3 EXPEDITION3 trial has been abandoned, as Solanezumab failed to slow cognitive decline in tests on around 2,000 patients with Alzheimer’s Disease. Several other amyloid-clearance drugs are going through trials apparently. Full Text Link Reference Walsh, F. … Continue reading
Posted in BBC News, For Researchers (mostly), In the News, International, Pharmacological Treatments, Quick Insights, Universal Interest
Tagged Alzheimer’s and Dementia (Journal), Alzheimer’s Disease Clinical Trials, Amyloid, Amyloid Beta, Amyloid Beta Protein, Amyloid Proteins, Amyloid-β (Aβ), Amyloid-β (Aβ) Accumulation, Avid Radiopharmaceuticals (Philadelphia), BBC Health News, Big Pharma, Clearance of Amyloid Beta Protein, Drug Trials, Drug Trials Failure Rate, Eli Lilly, Eli Lilly and Company (Indianapolis), EXPEDITION Studies, Intervention Trials, β-amyloid, LZAM, LZAN, Mild Alzheimer’s Disease, Misfolded Proteins, Neurofibrillary Tangles, Neuronal Loss, Progression of Mild Cognitive Impairment to Dementia, Progression to Alzheimer's Disease, Reasons for Termination of Trials, Solanezumab (Eli Lilly), Solanezumab EXPEDITION Trials, Solanezumab for Mild-to-Moderate Alzheimer’s Disease, Solanezumab Trials, Solanezumab: Humanised Monoclonal Antibody, United States, USA
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National Screening for Dementia Not Recommended (UK NSC / AHRQ / Annals of Internal Medicine / Epidemiology / International Journal of Epidemiology)
Summary The UK National Screening Committee (UK NSC) has upheld previous recommendations against screening people aged 65 and over for dementia. This decision follows an extensive review of the evidence. The UK NSC has concluded that tests for dementia, which … Continue reading
Posted in Acute Hospitals, Community Care, Department of Health, Diagnosis, For Doctors (mostly), For Nurses and Therapists (mostly), For Researchers (mostly), Guidelines, Models of Dementia Care, National, NHS, Patient Care Pathway, Person-Centred Care, Practical Advice, Public Health England, Quick Insights, Standards, UK, Universal Interest
Tagged (Hepatocellular Carcinoma: Alphafetoprotein), Activities of Daily Living (ADL), Activities of Daily Living Scale, ADAS-Cog, ADAS-Cog: Alzheimer’s Disease Assessment Scale - Cognitive Subscale, Addenbrooke's Cognitive Examination (ACE), Addenbrooke's Cognitive Examination-Revised (ACE-R), Alzheimer's Disease Assessment Scale (ADAS-Cog11), Alzheimer’s Early Screening, Annals of Internal Medicine, Australia, Benefits of Detection and Early Intervention, Best Interest Decisions, Best Interests, Best Interests of Patients, Blackfriars Consensus Statement, Bond University, Brief Assessments, Cambridge Cognitive Examination (CAMCOG), CAMCOG-R: Cambridge Cognitive Examination-Revised, Case Finding, Case Finding for Patients with Dementia, Centre for Research in Evidence-Based Practice: Bond University, CERAD-NP, Clock Drawing Test, Clock Drawing Test (CDT), Cognition Disorders, Cognitive Assessment Tools, Cognitive Impairment, Complex Best Interests Decision Making, Consortium to Establish a Registry for Alzheimer’s Disease – NP (CERAD-NP), Counter-Intuitive Screening Evidence, Counterintuitive Screening Evidence, Dementia Case Finding, Dementia Case Finding Scheme, Dementia Challenge, Dementia Diagnosis, Dementia Screening, Dementia Screening Debate, DemTect, Department of Medicine: Stanford University School of Medicine, Department of Statistics: Stanford University School of Humanities and Sciences, Diagnosis and Referral, Diagnosis and Support, Diagnosis Gap, Diagnosis of Dementia, Diagnosis Rates, Difficult Conversations, Doctor-Patient Relationships, Dr Anne Mackie: Director of Programmes (UK NSC), Dr Charles Alessi: Dementia Lead for PHE, Early Diagnosis, Early Diagnosis of Alzheimer's Disease, Early Screening, Effectiveness of Early Detection and Treatment, Ethical Considerations, Ethical Dilemmas, Ethical Issues of Dementia Care, Ethics and Decision-Making, General Practice, GPs, Harms of Detection and Early Intervention or Treatment, Improving Diagnosis, Incentive Payments, International Journal of Epidemiology, International Journal of Geriatric Psychiatry, Mass Screening, MCI: Mild Cognitive Impairment, Memory Assessments, Mild Cognitive Impairment, Mild Cognitive Impairment (MCI), Montreal Cognitive Assessment (MoCA), Neuropsychological Tests, olutions for Public Health (SPH), Opinions About Meaning of Overdiagnosis: National Community Survey of Australians, PHE: Public Health England, Picture Based Assessments, Population Screening for Dementia Deyond Passive Case-Finding, Post-Diagnosis Support, Pre-Dementia (MCI), Prevalence of Cognitive Impairment, Primary Prevention Interventions, Prime Minister's Challenge on Dementia, Prime Minister’s Dementia Challenge, Progression of Mild Cognitive Impairment to Dementia, Quality Premium Payments, Recommendation against national dementia screening. London: Public Health England (PHE), Risk Assessment, Risk of Overdiagnosis Associated With Screening, Rowland Universal Dementia Assessment Scale (RUDAS), School of Public Health: University of Sydney, Screening, Screening for Cognitive Impairment, Screening for Cognitive Impairment in Older Adults, Screening for Dementia, Screening Programmes, Screening Tests, Screening: Counter-Intuitive Evidence, Screening: Counter-Intuitive Evidence (Abdominal Aortic Aneurysm), Screening: Counter-Intuitive Evidence (Abdominal Aortic Aneurysm: Ultrasound), Screening: Counter-Intuitive Evidence (Breast Cancer), Screening: Counter-Intuitive Evidence (Breast Cancer: Breast Self-Exam), Screening: Counter-Intuitive Evidence (Breast Cancer: Clinical Breast Exam), Screening: Counter-Intuitive Evidence (Breast Cancer: Mammography), Screening: Counter-Intuitive Evidence (Cardiovascular Disease), Screening: Counter-Intuitive Evidence (Cardiovascular Disease: Echocardiography), Screening: Counter-Intuitive Evidence (Cervical Cancer), Screening: Counter-Intuitive Evidence (Cervical Cancer: Cytology), Screening: Counter-Intuitive Evidence (Cervical Cancer: Human Papilloma Virus), Screening: Counter-Intuitive Evidence (Cervical Cancer: Visual Inspection), Screening: Counter-Intuitive Evidence (Colorectal Cancer), Screening: Counter-Intuitive Evidence (Colorectal Cancer: Faecal Occult Blood Test [FOBT]), Screening: Counter-Intuitive Evidence (Colorectal Cancer: Fecal Occult Blood Test [FOBT]), Screening: Counter-Intuitive Evidence (Colorectal Cancer: Flexible Sigmoidoscopy With or Without FOBT), Screening: Counter-Intuitive Evidence (Colorectal Cancer: Flexible Sigmoidoscopy), Screening: Counter-Intuitive Evidence (Colorectal Cancer: Single Flexible Sigmoidoscopy), Screening: Counter-Intuitive Evidence (Hepatocellular Carcinoma), Screening: Counter-Intuitive Evidence (Hepatocellular Carcinoma: Alphafetoprotein and Ultrasound), Screening: Counter-Intuitive Evidence (Lung Cancer), Screening: Counter-Intuitive Evidence (Lung Cancer: CA-125), Screening: Counter-Intuitive Evidence (Lung Cancer: Chest X-Ray), Screening: Counter-Intuitive Evidence (Lung Cancer: Chest X-Ray and Cytology), Screening: Counter-Intuitive Evidence (Lung Cancer: CT Scan), Screening: Counter-Intuitive Evidence (Multiple Flexible Sigmoidoscopy), Screening: Counter-Intuitive Evidence (Oral Cancer), Screening: Counter-Intuitive Evidence (Oral Cancer: Visual Exam), Screening: Counter-Intuitive Evidence (Ovarian Cancer), Screening: Counter-Intuitive Evidence (Ovarian Cancer: CA–125), Screening: Counter-Intuitive Evidence (Prostate Cancer), Screening: Counter-Intuitive Evidence (Prostate Cancer: Prostate-Specific-Antigen), Screening: Counter-Intuitive Evidence (Type 2 Diabetes), Screening: Counter-Intuitive Evidence (Type 2 Diabetes: Fasting Blood Glucose and HbA1c), Solutions for Public Health (SPH) Review, Stanford Prevention Research Center: Stanford University School of Medicine, Stanford University School of Medicine, Systematic Population Dementia Screening Programme: Not Recommended (UK NSC), Target Culture, Target-Driven Behaviour, Target-Driven Priorities, Targeted Screening, Timely Diagnosis, Trail Making Assessments, Trail Making Test, Trail Making Tests, Transition from Cognitive Impairment to Dementia, U.S. Preventive Services Task Force (USPSTF), UK National Screening Committee, UK National Screening Committee (UK NSC), United States Preventive Services Task Force, United States Preventive Services Task Force (USPSTF), University of Sydney, USA Department of Health Research and Policy, USA Department of Health Research and Policy: Stanford University School of Medicine, Verbal Fluency, Verbal Fluency Assessments
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Mild Cognitive Impairment: Diagnosis and Management (JAMA)
Summary Mild cognitive impairment (MCI), defined as the “pre-dementia stage on the continuum of cognitive decline, characterized by objective impairment in cognition that is not severe enough to require help with usual activities of daily living”, tends to occur in … Continue reading
Posted in Community Care, For Nurses and Therapists (mostly), For Researchers (mostly), International, Non-Pharmacological Treatments, Pharmacological Treatments, Quick Insights, Systematic Reviews, Universal Interest
Tagged Aerobic Exercise, Cognitive Activity, Cognitive Decline, Department of Internal Medicine, Department of Neurology and Stroke Program: University of Michigan, Institute for Healthcare Policy and Innovation: University of Michigan, Institute for Social Research: University of Michigan, Institute of Gerontology: University of Michigan, JAMA, Late-Life Cognitive Decline, MCI, MCI: Mild Cognitive Impairment, Mental Wellbeing, Mild Cognitive Impairment, Mild Cognitive Impairment (MCI), Mild Cognitive Impairment More Prevalent in Men, National Institute on Aging (NIA), Physical Activity, Physical Activity as a Protective Factor for Cognitive Decline and Dementia, Pre-Dementia (MCI), Primary Care, Progression of Mild Cognitive Impairment to Dementia, Rates of Conversion From Mild Cognitive Impairment to Dementia, Risk and Protective Factors for Cognitive Decline and Dementia, Social Engagement, Social Inclusion, United States, University of Michigan, USA, Veterans Affairs Center for Clinical Management Research: Michigan
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