Tag Archives: Protein-Based Biomarkers in Blood May Deliver Accurate Diagnoses

Blood Test Able to Predict Alzheimer’s Disease Decades Before Symptoms? (BBC News / Neurology)

Summary Research published in the Neurology journal claims a significant breakthrough in the development of a blood test (for plasma Aβ42/Aβ40) which may be able to predict Alzheimer’s Disease onset with 94% accuracy. Due caution: “But it’s important to note … Continue reading

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More on Possible Blood Tests for Pre-Symptomatic Alzheimer’s Disease (NHS Digital / Nature Medicine)

Summary People with a rare hereditary form of Alzheimer’s Disease (Dominantly Inherited Alzheimer’s Disease) have raised levels of a protein called neurofilament light chain (NfC) in their blood, arising from damage to previously healthy nerve cells. These elevated levels of … Continue reading

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Blood Test for Pre-Symptomatic Alzheimer’s Disease Likely to Arrive Soon? (BBC News / Nature)

Summary A blood test developed by researchers in Australia and Japan appears to be able to predict the risk of developing Alzheimer’s Disease, with 90% accuracy. Detection of amyloid beta in the blood may be taken as a biomarker for … Continue reading

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Earlier Diagnosis Research: the Deep and Frequent Phenotyping Study (BBC News / GtR)

Summary The Deep and Frequent Phenotyping Study aims to discover new ways of diagnosing dementia, ideally decades before the symptoms become apparent in order to give future drug treatments the best chance of working. The Deep and Frequent Phenotyping Study … Continue reading

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Huntington’s Disease: a Blood Test “Speedometer”? (BBC News / Lancet Neurology)

Summary Early research shows promise that a protein biomarker in the blood, called neurofilament light chain (NFL), which is released from damaged brain cells in Huntington’s Disease, may be the basis for a blood test able to predict whether people … Continue reading

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Deep and Frequent Phenotyping Study: Dementia Early Detection and Biomarkers Research Programme (MRC / NIHR)

Summary The Deep and Frequent Phenotyping Study will explore improvements in biomarker research and the development of tests to detect Alzheimer’s Disease early on. This research programme will be funded by the National Institute of Health Research (NIHR) and the … Continue reading

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