-
Recent Posts
- International Perspectives on the Possible Impact of the COVID-19 Pandemic and Lockdown on Abuse of the Elderly (JGCR / American Journal of Geriatric Psychiatry / JAGS)
- Updates Relating to the Lancet Commission on Dementia Prevention, Intervention, and Care (Lancet / Alzheimer’s Research and Therapy / Alzheimer’s and Dementia)
- A Brief Review of How the COVID-19 Pandemic Relates to Elderly Care and Research (JGCR)
- Some Speculated / Potential Benefits of COVID-19 (JGCR / BBC Radio 4’s Rethink / BGS)
- Timeless Good Advice? (Action for Happiness)
Archives
- August 2020
- June 2020
- April 2020
- March 2020
- February 2020
- January 2020
- December 2019
- November 2019
- October 2019
- September 2019
- August 2019
- July 2019
- June 2019
- May 2019
- April 2019
- March 2019
- February 2019
- January 2019
- December 2018
- November 2018
- October 2018
- September 2018
- August 2018
- July 2018
- June 2018
- May 2018
- April 2018
- March 2018
- February 2018
- January 2018
- December 2017
- November 2017
- October 2017
- September 2017
- August 2017
- July 2017
- June 2017
- May 2017
- April 2017
- March 2017
- February 2017
- January 2017
- December 2016
- November 2016
- October 2016
- September 2016
- August 2016
- July 2016
- June 2016
- May 2016
- April 2016
- March 2016
- February 2016
- January 2016
- December 2015
- November 2015
- October 2015
- September 2015
- August 2015
- July 2015
- June 2015
- May 2015
- April 2015
- March 2015
- February 2015
- January 2015
- December 2014
- November 2014
- October 2014
- September 2014
- August 2014
- July 2014
- June 2014
- May 2014
- April 2014
- March 2014
- February 2014
- January 2014
- December 2013
- November 2013
- October 2013
- September 2013
- August 2013
- July 2013
- June 2013
- May 2013
- April 2013
- March 2013
- February 2013
- January 2013
- December 2012
- November 2012
- October 2012
- September 2012
- August 2012
- July 2012
- June 2012
- May 2012
- April 2012
- March 2012
- February 2012
- January 2012
- December 2011
- November 2011
- October 2011
- September 2011
- August 2011
- July 2011
- June 2011
- May 2011
- April 2011
- March 2011
- February 2011
- January 2011
- December 2010
- November 2010
Categories
- Antipsychotics
- Assistive Technology
- Charitable Bodies
- Commissioning
- Delirium
- Depression
- Enhancing the Healing Environment
- Falls
- Falls Prevention
- Guidelines
- Hip Fractures
- Housing
- Hypertension
- In the News
- Integrated Care
- International
- Local Interest
- Mental Health
- Models of Dementia Care
- National
- ADASS
- All-Party Parliamentary Group (APPG) on Dementia
- BSI
- CQC: Care Quality Commission
- Department of Health
- Department of Health and Social Care (DHSC)
- Health Education England (HEE)
- Housing LIN
- MAGDR
- Mental Health Foundation
- Mental Health Network (NHS Confederation)
- MHP Health Mandate
- National Audit Office
- National Voices
- NEoLCIN
- NEoLCP
- NHS
- NHS Alliance
- NHS Confederation
- NHS Employers
- NHS England
- NHS Evidence
- NHS Improvement
- NICE Guidelines
- NIHR
- NIHRSDO
- Northern Ireland
- Patients Association
- Public Health England
- RCN
- Royal College of Physicians
- Royal College of Psychiatrists
- SCIE
- Scotland
- UK
- UK NSC
- Wales
- Non-Pharmacological Treatments
- Nutrition
- Pain
- Parkinson's Disease
- Patient Care Pathway
- Person-Centred Care
- Personalisation
- Pharmacological Treatments
- Proposed for Next Newsletter
- Quick Insights
- Standards
- Statistics
- Stroke
- Systematic Reviews
- Telecare
- Telehealth
- Universal Interest
Google Translate (100+ Languages)
Tag Archives: Protein Plaques
Patterns in the Development of Alzheimer’s Disease? (NHS Choices / Science Advances)
Summary Patterns of gene activity (gene expression) in specific areas of the brain may help explain why Alzheimer’s Disease tends to start in certain regions before spreading further through the brain. “ …those regions of the brain in which tissues … Continue reading
Posted in For Doctors (mostly), For Researchers (mostly), In the News, NHS Digital (Previously NHS Choices), Quick Insights, UK, Universal Interest
Tagged Abnormal Proteins, Abnormal Proteins (Tau), Aβ Accumulation, Aβ Seeds, Aβ-Plaques, Allen Brain Atlas, Allen Brain Atlas: 3-D Digital Images of Gene Expression, Amyloid and Tau Imaging, Amyloid Beta Protein, Amyloid-β (Aβ), Amyloid-β (Aβ) Accumulation, Behind the Headlines, Braak Staging, Braak Staging of Alzheimer’s Disease, Department of Chemistry: University of Cambridge, Department of Molecular Biosciences: Northwestern University, Histopathological Staging of Alzheimer's Disease, Immune System, Immune System and Neurodegenerative Diseases, Levels of Genes Associated with Inflammation Mapped to Brain Areas, Mapping Brain Areas Affected in Early-Stage Alzheimer's Disease, Mapping Brain Areas Genetically Primed For Protein Overgrowth, Mapping Brain Areas Showing First Signs of Alzheimer's Disease, Mapping Brain Areas Susceptible to Protein Growth Due to Levels of Protein Expression, Mapping Brain Areas Vulnerable to Protein Overgrowth, Mapping Brain Areas: Allen Brain Atlas, Neurofibrillary Tangles, Northwestern University (USA), Pathological Staging, Patterns in the Development of Alzheimer’s Disease, Protein Aggregation, Protein Homeostasis, Protein Misfolding, Protein Overgrowth, Protein Plaques, Protein Seeds (Amyloid), Science Advances, Tau Aggregation, Tau Tangles, Tissue-Specific Progression of Alzheimer's Disease, University of Cambridge, USA, Vulnerability Patterns for Alzheimer's Disease
Leave a comment
EPPS Clears Amyloid Plaques in Mice: Alzheimer’s Disease Potentially Reversible? (BBC News / NHS Choices / Nature Communications)
Summary Korean researchers have identified a chemical (EPPS) which appears to be capable of clearing amyloid plaques from the brains of transgenic mice. The amount of plaques present in these animals’ brains was reduced in treated mice, and the treated … Continue reading
Posted in Animal Studies, BBC News, For Researchers (mostly), In the News, International, NHS Digital (Previously NHS Choices), Quick Insights, Universal Interest
Tagged 4-(2-hydroxyethyl)-1-piperazinepropanesulphonic acid (EPPS), Aβ-Plaques, Amyloid, Amyloid Beta Protein, Amyloid Hypothesis, Amyloid Precursor Protein (APP), Amyloid Proteins, Amyloid-Beta Clearance in APP Transgenic Mice, Amyloid-β Protein, Amyloidopathy, Anti-Amyloid Therapies, APP/PS1 Transgenic Mouse Model, BBC Health News, Behind the Headlines, Beta-Amyloid Plaques, Biological Chemistry Program: Korea University of Science and Technology (UST), Brain Science Institute: Korea Institute of Science and Technology (KIST), Center for Neuro-Medicine: Korea Institute of Science and Technology (KIST), Center for Neuroscience: Korea Institute of Science and Technology (KIST), EPPS Removal of Ab Plaques and Oligomers in APP/PS1 Mice, EPPS Rescues Hippocampus-Dependent Cognitive Deficits (in Mice), GoshenBiotech Inc, Korea, Korea Institute of Science and Technology, Korea Institute of Science and Technology (KIST), Korea University of Science and Technology (UST), Mice, Nature Communications, Neurodegeneration, Neurodegenerative Research, Protein Plaques, Republic of Korea, Research Institute: GoshenBiotech Inc., Transgenic Mice
Leave a comment
Use of Anti-Depressants to Slow Alzheimer’s Disease Onset? (BBC News / Science Translational Medicine / PNAS)
Summary Recent research into transgenic mice (and early, small-scale investigations with people) suggests that the anti-depressant citalopram could be used to slow the onset of Alzheimer’s Disease. This work in the United States appears to show that citalopram may counteract … Continue reading
Posted in Animal Studies, BBC News, For Researchers (mostly), In the News, International, Quick Insights, Universal Interest
Tagged Amyloid Beta, Amyloid Proteins, Amyloid-β (Aβ), Amyloid-β (Aβ) Accumulation, Antidepressants, Antidepressive Agents, Avid Radiopharmaceuticals, BBC Health News, Beta-Amyloid, Beta-Amyloid Plaques, Citalopram, CSF Aβ Production, Department of Neurology: Washington University, Department of Neurology: Washington University School of Medicine, Eli Lilly Inc., Genetically Engineered Mice, Hope Center for Neurological Disorders: Washington University, Hope Center for Neurological Disorders: Washington University School of Medicine, β-amyloid, Knight Alzheimer's Disease Research Center, Knight Alzheimer's Disease Research Center: Washington University Medical Center, Mice, Mouse Model of Alzheimer's Disease, Off-Label Drug Repurposing Trials, Pittsburgh Compound B (PIB), PNAS, Positron Emission Tomography (PET), Potential Repurposing of Drugs to Slow Progression of Alzheimer’s Disease, Proceedings of the National Academy of Sciences (PNAS), Proceedings of the National Academy of Sciences of the United States of America (PNAS), Protein Plaques, Repurposing of Drugs, Science Translational Medicine, Selective Serotonin Reuptake Inhibitors (SSRIs), SSRIs: Selective Serotonin Reuptake Inhibitors, Transgenic Mice, United States, University of Pennsylvania, University of Washington, USA, Washington University Medical Center, Washington University School of Medicine
Leave a comment
