Tag Archives: PSEN1: Presenilin 1 Mutation

Genetic Mutation Which Delays Alzheimer’s Disease? (NHS Choices / Molecular Psychiatry)

Summary A study of 71 persons from an extended family (comprising around 5,000 people) in northern Colombia, who carry a mutation in a gene called PSEN1 (the so-called the Paisa mutation, which causes a rare, severe form of early-onset Alzheimer’s disease), … Continue reading

Posted in For Researchers (mostly), In the News, International, NHS Digital (Previously NHS Choices), Quick Insights, Statistics, Universal Interest | Tagged , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , | Leave a comment

Stages in the Progression to Alzheimer’s Disease

Abstract Mild cognitive impairment (MCI) and pre-MCI are stages which precede Alzheimer’s Disease (AD) dementia. The authors assessed descendants of individuals with a mutation in presenilin 1 (PSEN1) which causes familial Alzheimer’s Disease, hoping to identify distinct stages in the … Continue reading

Posted in For Doctors (mostly), For Researchers (mostly), Universal Interest | Tagged , , , , , , , | Leave a comment