Tag Archives: Selective Serotonin Reuptake Inhibitors (SSRIs)

Antidepressants Not Recommended for Depression in People With Dementia (NIHR Signal / Cochrane Database)

Summary A National Institute for Health Research “Signal” expert commentary refers to a systematic review which indicates that antidepressants are unsuitable / unhelpful for the treatment of depression in persons living with dementia. Full Text Link Reference Antidepressants do not … Continue reading

Posted in Acute Hospitals, Community Care, For Carers (mostly), For Doctors (mostly), For Nurses and Therapists (mostly), For Researchers (mostly), International, Management of Condition, Mental Health, Models of Dementia Care, NIHR, Person-Centred Care, Pharmacological Treatments, Quick Insights, Systematic Reviews, UK, Universal Interest | Tagged , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , | Leave a comment

Risk of Dementia in Patients Using Antidepressants? (Behavioural Neurology / BBC News)

Summary Evidence indicating that use of antidepressants is associated significantly with an increased risk of developing dementia: Full Text Link Reference Wang, YC. Tai, PA. [and] Poly, TN. [et al] (2018). Increased risk of dementia in patients with antidepressants: a … Continue reading

Posted in BBC News, For Doctors (mostly), For Nurses and Therapists (mostly), For Researchers (mostly), In the News, International, Pharmacological Treatments, Quick Insights, Systematic Reviews, Universal Interest | Tagged , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , | Leave a comment

Pharmacological Treatment of Agitation in Persons With Dementia (British Journal of Clinical Pharmacology)

Summary A systematic review and meta‐analysis of pharmaceutical treatments for alleviating agitation in dementia has been performed. Regarding the efficacy and treatment acceptability of these medications, it is reported that: “Risperidone, SSRIs as a class and Dextromethorphan / Quinidine demonstrated … Continue reading

Posted in Antipsychotics, For Doctors (mostly), For Nurses and Therapists (mostly), For Researchers (mostly), International, Mental Health, Pharmacological Treatments, Quick Insights, Systematic Reviews | Tagged , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , | Leave a comment

Use of Anti-Depressants to Slow Alzheimer’s Disease Onset? (BBC News / Science Translational Medicine / PNAS)

Summary Recent research into transgenic mice (and early, small-scale investigations with people) suggests that the anti-depressant citalopram could be used to slow the onset of Alzheimer’s Disease. This work in the United States appears to show that citalopram may counteract … Continue reading

Posted in Animal Studies, BBC News, For Researchers (mostly), In the News, International, Quick Insights, Universal Interest | Tagged , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , | Leave a comment

Recent Systematic Reviews and Meta-Analyses on Pharmacological Treatments

Some of the following articles are available freely, but a suitable Athens password, a journal subscription or one-off payment may be needed for access to the full-text of the other articles. The Bibliographic Citations Irwin, R.W. [and] Brinton, R.D. (2013). … Continue reading

Posted in For Doctors (mostly), For Researchers (mostly), International, Management of Condition, Pharmacological Treatments, Systematic Reviews | Tagged , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , | Leave a comment

Discontinuation of Antidepressants in People with Dementia and Neuropsychiatric Symptoms (DESEP Study) (BMJ)

[A version of this item appears in: Dementia: the Latest Evidence Newsletter (RWHT), Volume 2 Issue 9, April 2012]. Summary Roughly 80% of nursing home residents have dementia in Norway. 90% have neuropsychiatric symptoms. Roughly 40% of residents in Norwegian … Continue reading

Posted in Acute Hospitals, Community Care, Depression, For Doctors (mostly), For Researchers (mostly), International, Management of Condition, Pharmacological Treatments | Tagged , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , | Leave a comment

Sedative Load of Medications Prescribed for Older People with Dementia in Care Homes (BMC Geriatrics)

Summary This study measured the sedative load and use of sedative and psychotropic medications in older people with dementia living in six UK residential care homes. The sedative load model has been used previously to determine the sedative load for residents … Continue reading

Posted in Community Care, For Researchers (mostly), For Social Workers (mostly), Management of Condition, Pharmacological Treatments, Universal Interest | Tagged , , | Leave a comment