Tag Archives: SSRIs: Selective Serotonin Reuptake Inhibitors

Risk of Dementia in Patients Using Antidepressants? (Behavioural Neurology / BBC News)

Summary Evidence indicating that use of antidepressants is associated significantly with an increased risk of developing dementia: Full Text Link Reference Wang, YC. Tai, PA. [and] Poly, TN. [et al] (2018). Increased risk of dementia in patients with antidepressants: a … Continue reading

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Pharmacological Treatment of Agitation in Persons With Dementia (British Journal of Clinical Pharmacology)

Summary A systematic review and meta‐analysis of pharmaceutical treatments for alleviating agitation in dementia has been performed. Regarding the efficacy and treatment acceptability of these medications, it is reported that: “Risperidone, SSRIs as a class and Dextromethorphan / Quinidine demonstrated … Continue reading

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Use of Anti-Depressants to Slow Alzheimer’s Disease Onset? (BBC News / Science Translational Medicine / PNAS)

Summary Recent research into transgenic mice (and early, small-scale investigations with people) suggests that the anti-depressant citalopram could be used to slow the onset of Alzheimer’s Disease. This work in the United States appears to show that citalopram may counteract … Continue reading

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Recent Systematic Reviews and Meta-Analyses on Pharmacological Treatments

Some of the following articles are available freely, but a suitable Athens password, a journal subscription or one-off payment may be needed for access to the full-text of the other articles. The Bibliographic Citations Irwin, R.W. [and] Brinton, R.D. (2013). … Continue reading

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Discontinuation of Antidepressants in People with Dementia and Neuropsychiatric Symptoms (DESEP Study) (BMJ)

[A version of this item appears in: Dementia: the Latest Evidence Newsletter (RWHT), Volume 2 Issue 9, April 2012]. Summary Roughly 80% of nursing home residents have dementia in Norway. 90% have neuropsychiatric symptoms. Roughly 40% of residents in Norwegian … Continue reading

Posted in Acute Hospitals, Community Care, Depression, For Doctors (mostly), For Researchers (mostly), International, Management of Condition, Pharmacological Treatments | Tagged , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , | Leave a comment

Antidepressants for Agitation and Psychosis in Dementia (Cochrane Review)

[A version of this abstract appears in: Dementia: the Latest Evidence Newsletter (RWHT), Volume 1 Issue 9, April 2011]. Abstract Psychosis and agitation occur commonly in older adults with dementia. Medications prescribed to treat these symptoms increasingly include antidepressants. This systematic review examines … Continue reading

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