Tag Archives: Tau Aggregation

Structure of Tau Filaments in Alzheimer’s Disease Discovered (MRC / BBC News / Nature / NHS Choices)

Summary Research at the MRC Laboratory of Molecular Biology has taken advantage of a “resolution revolution” in microscopy to uncover the atomic structure of Tau filaments (one of the two types of the abnormal tangles associated with Alzheimer’s Disease). “Tau forms … Continue reading

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Another Recent Alzheimer’s Disease Drug Trial Disappointment (Lancet)

Summary Researchers aimed to discover whether LMTM [Leuco-methylthioninium bis(hydromethanesulfonate] might be safe and effective for slowing disease progression in patients with mild to moderate Alzheimer’s Disease. LMTM had previously been found to work as a selective inhibitor of tau protein … Continue reading

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Patterns in the Development of Alzheimer’s Disease? (NHS Choices / Science Advances)

Summary Patterns of gene activity (gene expression) in specific areas of the brain may help explain why Alzheimer’s Disease tends to start in certain regions before spreading further through the brain. “ …those regions of the brain in which tissues … Continue reading

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Faintest Hints of Promise From a Recent Dementia Drug Trial? (BBC News / Alzheimer’s Association International Conference)

Summary Data from a recent trial involving 891 patients, presented at the Alzheimer’s Association International Conference in Toronto this week, indicates that an experimental new drug (LMTX) appears to slow the death of brain cells and preserve mental function in … Continue reading

Posted in Alzheimer’s Disease International (ADI), BBC News, Charitable Bodies, For Doctors (mostly), For Nurses and Therapists (mostly), For Researchers (mostly), In the News, International, Management of Condition, Models of Dementia Care, Pharmacological Treatments, Quick Insights, Universal Interest | Tagged , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , | Leave a comment