Tag Archives: UK National Institute of Health Research HTA Programme

Unexpected Results From the Dementia and Physical Activity (DAPA) Trial? (Pharmacoeconomics Open / JAD)

Summary Previous research has suggested that physical exercise has the potential to slow the progression of dementia in people with pre-existing mild cognitive impairment through to moderate dementia. Evidence for the cost-effectiveness of structured physical activity programmes has been lacking, … Continue reading

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Sertraline or Mirtazapine Versus a Placebo for Treatment of Depression in Dementia (HTA-SADD Trial)

Summary This randomised control trial took place across nine English old-age psychiatry units. It examined the clinical effectiveness of sertraline and mirtazapine in reducing depression compared with a placebo. 326 patients with Alzheimer’s Disease (AD), depression and a Cornell Scale … Continue reading

Posted in Acute Hospitals, Community Care, Depression, For Doctors (mostly), For Researchers (mostly), Management of Condition, Mental Health, National, NHS, Pharmacological Treatments, Quick Insights, Systematic Reviews, UK, Universal Interest | Tagged , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , | Leave a comment

Health Technology Assessment Study into the Use of Antidepressants for Depression in Dementia (HTA-SADD)

[A version of this item appears in: Dementia: the Latest Evidence Newsletter (RWHT), Volume 2 Issue 1, August 2011]. Summary Research into the efficacy and safety of two of the most commonly prescribed drugs, sertraline and mirtazapine, has found that these treatments … Continue reading

Posted in Acute Hospitals, Community Care, Depression, For Doctors (mostly), For Researchers (mostly), In the News, Management of Condition, Pharmacological Treatments, Quick Insights, Universal Interest | Tagged , , , , , , , | Leave a comment