Tag Archives: University of Rochester School of Medicine and Dentistry

Pharmacological Treatment for Agitation in Alzheimer’s Disease? (JAMA)

Summary Combination dextromethorphan-quinidine shows early signs of being a safe and effective treatment option for Alzheimer’s Disease-related agitation. Full Text Link Reference Cummings, JL. Lyketsos, CG. [and] Peskind, ER. [et al] (2015). Effect of dextromethorphan-quinidine on agitation in patients with … Continue reading

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Reducing Antipsychotic Prescribing for BPSD (BMJ / JAMA / JAMA Psychiatry / BJCP)

Summary This BMJ “Change page” article discusses the potential harms associated with use of antipsychotics in people with dementia, and covers guidelines recommending restrictions in their use. Risperidone is the antipsychotic recommended for use in the treatment of aggression associated … Continue reading

Posted in Acute Hospitals, Antipsychotics, Community Care, For Doctors (mostly), For Nurses and Therapists (mostly), For Researchers (mostly), International, Management of Condition, Mental Health, Models of Dementia Care, Non-Pharmacological Treatments, Person-Centred Care, Pharmacological Treatments, Practical Advice, Quick Insights, Standards, Statistics, UK | Tagged , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , | Leave a comment

Bapineuzumab Trials Results in Mild-to-Moderate Alzheimer’s Disease (New England Journal of Medicine)

Summary Bapineuzumab is an anti-amyloid-beta monoclonal antibody, which had shown promise for the treatment of Alzheimer’s Disease. Two double-blind, randomised, placebo-controlled, phase 3 trials have been conducted, involving 2204 patients with mild-to-moderate Alzheimer’s disease. One trial involved 1121 carriers of … Continue reading

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Pesticides and Dementia

[This article first appeared in: Dementia Newsletter RWHT Volume 1 Issue 6 January 2011]. Abstract A study of 929 French vineyard workers found that those directly exposed to pesticides over a long period performed less well in tests of cognitive ability … Continue reading

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